Human Phenotype Ontology 
Grandparent Node:
expandAbnormal cell morphology (HP:0025461)help
Grandparent Node:
expandAbnormal heart morphology (HP:0001627)help
Parent Node:
expandAbnormal cardiomyocyte morphology (HP:0031331)help
..Starting node
..expandMyocardial sarcomeric disarray (HP:0031333)help
Term ID: 31333
Name: Myocardial sarcomeric disarray
Synonym: Cardiac biopsy: myocyte disarray; Cardiomyocyte disarray; Myocardial sarcomere disarray
Definition: A disruption of the structure of the sarcomeres of cardiomyocytes. The sarcomere is the repeating unit between two Z lines comprised largely of myosin and actin that mediates contractility, and normally sarcomeres are aligned with the long axis of cells, with the Z bands being in register throughout the length of the cardiac myocytes.
Comments:
Reference: HP:0031333
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal cadiomyocyte dystrophin staining (HP:0031339) help
..expandAbnormal cardiomyocyte connexin43 staining (HP:0031337) help
..expandAbnormal cardiomyocyte mitochondrial morphology (HP:0031335) help
..expandAbnormal cardiomyocyte plakoglobin staining (HP:0031338) help
..expandCardiomyocyte degeneration (HP:0031332) help
..expandCardiomyocyte hypertrophy (HP:0031319) help
..expandCardiomyocyte inclusion bodies (HP:0031334) help
..expandCardiomyocyte mitochondrial proliferation (HP:0031320) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031333HP:0031333Myocardial sarcomeric disarray0LMOD2 CL E G H4427216648OMIM:619897


Genes (1) :LMOD2

Diseases (1) :OMIM:619897
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.