Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of the neck (HP:0000464)help
Parent Node:
expandLimitation of neck motion (HP:0005986)help
..Starting node
..expandNuchal rigidity (HP:0031179)help
Term ID: 31179
Name: Nuchal rigidity
Synonym: Meningism
Definition: Resistance of the extensor muscles of the neck to being bent forwards (i.e., impaired neck flexion) as a result of muscle spasm of the extensor muscles of the neck. Nuchal rigidity is not a fixed rigidity. Nuchal rigidity has been used as a bedside test for meningism, although its sensitivity for this purpose has been debated.
Comments:
Reference: HP:0031179
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandLimited neck flexion (HP:0005991) help
..expandLimited neck range of motion (HP:0000466) help
..expandNeck joint contracture (HP:0005997) help
..expandStiff neck (HP:0025258) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031179HP:0031179Nuchal rigidity0ATP1A2 CL E G H477800ORPHA:569Familial or sporadic hemiplegic migraineHP:0040283 - Occasional239
HP:0031179HP:0031179Nuchal rigidity0CACNA1A CL E G H7731388ORPHA:569Familial or sporadic hemiplegic migraineHP:0040283 - Occasional449
HP:0031179HP:0031179Nuchal rigidity0IRF3 CL E G H36616118OMIM:616532Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 7.1
HP:0031179HP:0031179Nuchal rigidity0PRRT2 CL E G H11247630500ORPHA:569Familial or sporadic hemiplegic migraineHP:0040283 - Occasional94
HP:0031179HP:0031179Nuchal rigidity0SCN1A CL E G H632310585ORPHA:569Familial or sporadic hemiplegic migraineHP:0040283 - Occasional1053
HP:0031179HP:0031179Nuchal rigidity0TBK1 CL E G H2911011584ORPHA:1930Herpes simplex virus encephalitisHP:0040282 - Frequent20
HP:0031179HP:0031179Nuchal rigidity0TICAM1 CL E G H14802218348ORPHA:1930Herpes simplex virus encephalitisHP:0040282 - Frequent6
HP:0031179HP:0031179Nuchal rigidity0TLR3 CL E G H709811849ORPHA:1930Herpes simplex virus encephalitisHP:0040282 - Frequent3
HP:0031179HP:0031179Nuchal rigidity0TRAF3 CL E G H718712033ORPHA:1930Herpes simplex virus encephalitisHP:0040282 - Frequent2
HP:0031179HP:0031179Nuchal rigidity0UNC93B1 CL E G H8162213481ORPHA:1930Herpes simplex virus encephalitisHP:0040282 - Frequent5


Genes (10) :ATP1A2 CACNA1A IRF3 PRRT2 SCN1A TBK1 TICAM1 TLR3 TRAF3 UNC93B1

Diseases (3) :ORPHA:569 OMIM:616532 ORPHA:1930
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.