Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of the musculature of the hand (HP:0001421)

Parent Node:
Hand muscle weakness (HP:0030237)

..Starting node
..Finger flexor weakness (HP:0031177)

Term ID:

31177

Name:

Finger flexor weakness

Synonym:

Definition:

Reduced ability to flex (bend) the fingers. This can manifest as incomplete closure of the hand due to weakness in finger flexion.

Comments:

Reference:

HP:0031177

Genes and Diseases:

Child Nodes:

Sister Nodes:

Thenar muscle weakness (HP:0003427)

Weakness of long finger extensor muscles (HP:0009077)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031177	HP:0031177	Finger flexor weakness	0	DYSF CL E G H	8291	3097	ORPHA:178400	Distal myopathy with anterior tibial onset	HP:0040284 - Very rare	600
HP:0031177	HP:0031177	Finger flexor weakness	0	FLNC CL E G H	2318	3756	ORPHA:63273	Distal myopathy with posterior leg and anterior hand involvement	HP:0040282 - Frequent	197

Genes (2) :DYSF FLNC

Diseases (2) :ORPHA:178400 ORPHA:63273

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.