Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of skin physiology (HP:0011122)

Parent Node:
Pruritus (HP:0000989)

..Starting node
..Pruritis on hand (HP:0030899)

Term ID:

30899

Name:

Pruritis on hand

Synonym:

Definition:

Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased sensation of itching over the skin of the hand.

Comments:

Reference:

HP:0030899

Genes and Diseases:

Child Nodes:

........

Palmar pruritus (HP:0031248)

Sister Nodes:

Pruritis on abdomen (HP:0030898)

Pruritis on breast (HP:0030901)

Pruritus on foot (HP:0030900)

Vaginal pruritus (HP:0030161)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0030899	HP:0030899	Pruritis on hand	0	ABCB11 CL E G H	8647	42	ORPHA:69665	Intrahepatic cholestasis of pregnancy		146
HP:0030899	HP:0030899	Pruritis on hand	0	ABCB4 CL E G H	5244	45	ORPHA:69665	Intrahepatic cholestasis of pregnancy		111
HP:0030899	HP:0030899	Pruritis on hand	0	ATP8B1 CL E G H	5205	3706	ORPHA:69665	Intrahepatic cholestasis of pregnancy		144
HP:0030899	HP:0030899	Pruritis on hand	0	CFTR CL E G H	1080	1884	ORPHA:498359	Aquagenic palmoplantar keratoderma		1371
HP:0030899	HP:0030899	Pruritis on hand	0	NR1H4 CL E G H	9971	7967	ORPHA:69665	Intrahepatic cholestasis of pregnancy		14
HP:0030899	HP:0031248	Palmar pruritus	1	ABCB11 CL E G H	8647	42	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040283 - Occasional	146
HP:0030899	HP:0031248	Palmar pruritus	1	ABCB4 CL E G H	5244	45	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040283 - Occasional	111
HP:0030899	HP:0031248	Palmar pruritus	1	ATP8B1 CL E G H	5205	3706	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040283 - Occasional	144
HP:0030899	HP:0031248	Palmar pruritus	1	CFTR CL E G H	1080	1884	ORPHA:498359	Aquagenic palmoplantar keratoderma	HP:0040282 - Frequent	1371
HP:0030899	HP:0031248	Palmar pruritus	1	NR1H4 CL E G H	9971	7967	ORPHA:69665	Intrahepatic cholestasis of pregnancy	HP:0040283 - Occasional	14

Genes (5) :ABCB11 ABCB4 ATP8B1 CFTR NR1H4

Diseases (2) :ORPHA:69665 ORPHA:498359

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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