Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of skin morphology (HP:0011121)help
Parent Node:
expandAbnormal epidermal morphology (HP:0011124)help
..Starting node
..expandCivatte bodies (HP:0025115)help
Term ID: 25115
Name: Civatte bodies
Synonym: Colloid bodies; Colloid bodies of Civatte; Cytoid bodies; Hyaline bodies
Definition: Eosinophilic hyaline ovoid bodies which are often found in the subepidermal papillary regions or sometimes in the epidermis. Civatte bodies (CBs) are seen as rounded, homogenous, eosinophilic masses on routine H and E staining lying in the deeper parts of epidermis/epithelium and more frequently in dermis/connective tissue. They are known as CBs (in epithelium/epidermis), colloid bodies, or hyaline bodies (in connective tissue). They are 10-25 micrometers in diameter and situated mostly within or above the inflammatory cell infiltrate. In lichen planus, the number of necrotic keratinocytes may be so large that they are seen lying in clusters in the uppermost dermis. These bodies show a positive periodic acid Schiff reaction and are diastase resistant
Comments:
Reference: HP:0025115
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAcantholysis (HP:0100792) help
..expandEpidermal acanthosis (HP:0025092) help
..expandRete ridge flattening (HP:0025117) help
..expandScaling skin (HP:0040189) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0025115HP:0025115Civatte bodies0ABCC6 CL E G H36857OMIM:264800PSEUDOXANTHOMA ELASTICUM; PXE415
HP:0025115HP:0025115Civatte bodies0XYLT1 CL E G H6413115516OMIM:264800PSEUDOXANTHOMA ELASTICUM; PXE14
HP:0025115HP:0025115Civatte bodies0XYLT2 CL E G H6413215517OMIM:264800PSEUDOXANTHOMA ELASTICUM; PXE5


Genes (3) :ABCC6 XYLT1 XYLT2

Diseases (1) :OMIM:264800
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.