Human Phenotype Ontology 
Grandparent Node:
expandAbnormal renal glomerulus morphology (HP:0000095)help
Parent Node:
expandAbnormal glomerular mesangium morphology (HP:0001966)help
..Starting node
..expandMesangial hypercellularity (HP:0012574)help
Term ID: 12574
Name: Mesangial hypercellularity
Synonym: Mesangial proliferation
Definition: Increased numbers of mesangial cells per glomerulus, defined as more than 3 nuclei fully surrounded by matrix in one or more mesangial areas, not including perihilar region, on a standard 3-micron-thick tissue section, best evaluated on periodic acid-Schiff (PAS) stain.
Comments:
Reference: HP:0012574
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandDiffuse mesangial sclerosis (HP:0001967) help
..expandMesangiolysis (HP:0030762) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012574HP:0012574Mesangial hypercellularity0APOE CL E G H348613OMIM:611771LIPOPROTEIN GLOMERULOPATHY; LPG39
HP:0012574HP:0012574Mesangial hypercellularity0COPA CL E G H13142230OMIM:616414AUTOIMMUNE INTERSTITIAL LUNG, JOINT, AND KIDNEY DISEASE; AILJK5
HP:0012574HP:0012574Mesangial hypercellularity0KIRREL1 CL E G H5524315734OMIM:619201NEPHROTIC SYNDROME, TYPE 23; NPHS23
HP:0012574HP:0012574Mesangial hypercellularity0SGPL1 CL E G H887910817OMIM:617575Nephrotic syndrome, type 148
HP:0012574HP:0012574Mesangial hypercellularity0SPRY2 CL E G H1025311270OMIM:616818Iga nephropathy, susceptibility to, 31


Genes (5) :APOE COPA KIRREL1 SGPL1 SPRY2

Diseases (5) :OMIM:611771 OMIM:616414 OMIM:619201 OMIM:617575 OMIM:616818
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.