Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal urinary electrolyte concentration (HP:0012591)

Parent Node:
Abnormal urine potassium concentration (HP:0012598)

..Starting node
..Decreased urinary potassium (HP:0012364)

Term ID:

12364

Name:

Decreased urinary potassium

Synonym:

Decreased urinary K; Hypokaliuria; Hypokaluria; Low urine potassium levels

Definition:

A decreased concentration of potassium(1+) in the urine.

Comments:

Reference:

HP:0012364

Genes and Diseases:

Child Nodes:

Sister Nodes:

Increased urinary potassium (HP:0003081)

Renal potassium wasting (HP:0000128)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012364	HP:0012364	Decreased urinary potassium	0	CACNA1S CL E G H	779	1397	ORPHA:79102	Thyrotoxic periodic paralysis	HP:0040281 - Very frequent	247
HP:0012364	HP:0012364	Decreased urinary potassium	0	CLCNKB CL E G H	1188	2027	ORPHA:358	Gitelman syndrome	HP:0040284 - Very rare	27
HP:0012364	HP:0012364	Decreased urinary potassium	0	GABRA3 CL E G H	2556	4077	ORPHA:79102	Thyrotoxic periodic paralysis	HP:0040281 - Very frequent
HP:0012364	HP:0012364	Decreased urinary potassium	0	KCNJ18 CL E G H	100134444	39080	ORPHA:79102	Thyrotoxic periodic paralysis	HP:0040281 - Very frequent	10
HP:0012364	HP:0012364	Decreased urinary potassium	0	SERPINA6 CL E G H	866	1540	OMIM:611489	Corticosteroid-binding globulin deficiency		4
HP:0012364	HP:0012364	Decreased urinary potassium	0	SLC12A3 CL E G H	6559	10912	ORPHA:358	Gitelman syndrome	HP:0040284 - Very rare	145

Genes (6) :CACNA1S CLCNKB GABRA3 KCNJ18 SERPINA6 SLC12A3

Diseases (3) :ORPHA:79102 ORPHA:358 OMIM:611489

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.