Human Phenotype Ontology 
Grandparent Node:
expandAbnormal leukocyte count (HP:0011893)help
Grandparent Node:
expandAbnormal monocyte morphology (HP:0012144)help
Parent Node:
expandAbnormal monocyte count (HP:0012310)help
..Starting node
..expandMonocytosis (HP:0012311)help
Term ID: 12311
Name: Monocytosis
Synonym: High blood monocyte number
Definition: An increased number of circulating monocytes.
Comments:
Reference: HP:0012311
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandMonocytopenia (HP:0012312) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012311HP:0012311Monocytosis0CLPB CL E G H8157030664ORPHA:486Autosomal dominant severe congenital neutropeniaHP:0040282 - Frequent38
HP:0012311HP:0012311Monocytosis0DDX41 CL E G H5142818674OMIM:616871Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to23
HP:0012311HP:0012311Monocytosis0ELANE CL E G H19913309ORPHA:486Autosomal dominant severe congenital neutropeniaHP:0040282 - Frequent79
HP:0012311HP:0012311Monocytosis0ELANE CL E G H19913309OMIM:202700Neutropenia, severe congenital, 1, autosomal dominant.79
HP:0012311HP:0012311Monocytosis0G6PC3 CL E G H9257924861OMIM:612541Neutropenia, severe congenital, 4, autosomal recessive.37
HP:0012311HP:0012311Monocytosis0GFI1 CL E G H26724237ORPHA:486Autosomal dominant severe congenital neutropeniaHP:0040282 - Frequent56
HP:0012311HP:0012311Monocytosis0GFI1 CL E G H26724237OMIM:613107Neutropenia, severe congenital, 2, autosomal dominant.56
HP:0012311HP:0012311Monocytosis0KRAS CL E G H38456407OMIM:614470RAS-associated autoimmune lymphoproliferative syndrome type IV, somatic.196
HP:0012311HP:0012311Monocytosis0NRAS CL E G H48937989OMIM:614470RAS-associated autoimmune lymphoproliferative syndrome type IV, somatic.102
HP:0012311HP:0012311Monocytosis0PIK3CD CL E G H52938977OMIM:619281IMMUNODEFICIENCY 14B, AUTOSOMAL RECESSIVE; IMD14B9
HP:0012311HP:0012311Monocytosis0SRP54 CL E G H672911301ORPHA:486Autosomal dominant severe congenital neutropeniaHP:0040282 - Frequent
HP:0012311HP:0012311Monocytosis0TCIRG1 CL E G H1031211647ORPHA:486Autosomal dominant severe congenital neutropeniaHP:0040282 - Frequent82
HP:0012311HP:0012311Monocytosis0ZNFX1 CL E G H5716929271OMIM:619644IMMUNODEFICIENCY 91 AND HYPERINFLAMMATION; IMD91


Genes (11) :CLPB DDX41 ELANE G6PC3 GFI1 KRAS NRAS PIK3CD SRP54 TCIRG1 ZNFX1

Diseases (8) :ORPHA:486 OMIM:616871 OMIM:202700 OMIM:612541 OMIM:613107 OMIM:614470 OMIM:619281 OMIM:619644
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.