Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal male reproductive system physiology (HP:0012874)

Parent Node:
Functional abnormality of male internal genitalia (HP:0000025)

..Starting node
..Abnormal sperm motility (HP:0012206)

Term ID:

12206

Name:

Abnormal sperm motility

Synonym:

Abnormal sperm motility

Definition:

An anomaly of the mobility of ejaculated sperm.

Comments:

Reference:

HP:0012206

Genes and Diseases:

Child Nodes:

........

Reduced sperm motility (HP:0012207)

........

Nonmotile sperm (HP:0012208)

Sister Nodes:

Abnormal spermatogenesis (HP:0008669)

Male hypogonadism (HP:0000026)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012206	HP:0012206	Abnormal sperm motility	0	ALG5 CL E G H	29880	20266	ORPHA:730	Autosomal dominant polycystic kidney disease
HP:0012206	HP:0012206	Abnormal sperm motility	0	ALG9 CL E G H	79796	15672	ORPHA:730	Autosomal dominant polycystic kidney disease		93
HP:0012206	HP:0012206	Abnormal sperm motility	0	ARMC2 CL E G H	84071	23045	OMIM:618433	SPERMATOGENIC FAILURE 38; SPGF38
HP:0012206	HP:0012206	Abnormal sperm motility	0	BICC1 CL E G H	80114	19351	ORPHA:730	Autosomal dominant polycystic kidney disease		5
HP:0012206	HP:0012206	Abnormal sperm motility	0	BRDT CL E G H	676	1105	OMIM:617644	Spermatogenic failure 21		1
HP:0012206	HP:0012206	Abnormal sperm motility	0	CATIP CL E G H	375307	25062	OMIM:619379	SPERMATOGENIC FAILURE 54; SPGF54
HP:0012206	HP:0012206	Abnormal sperm motility	0	CATSPER1 CL E G H	117144	17116	OMIM:612997	Spermatogenic failure 7		45
HP:0012206	HP:0012206	Abnormal sperm motility	0	CATSPER2 CL E G H	117155	18810	OMIM:611102	Deafness, sensorineural, and male infertility		12
HP:0012206	HP:0012206	Abnormal sperm motility	0	CATSPER2 CL E G H	117155	18810	OMIM:612997	Spermatogenic failure 7		12
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC103 CL E G H	388389	32700	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	36
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC34 CL E G H	91057	25079	OMIM:620084
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC39 CL E G H	339829	25244	OMIM:613807	Ciliary dyskinesia, primary, 14		126
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC39 CL E G H	339829	25244	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	126
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC40 CL E G H	55036	26090	OMIM:613808	CILIARY DYSKINESIA, PRIMARY, 15; CILD15		182
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC40 CL E G H	55036	26090	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	182
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCDC65 CL E G H	85478	29937	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	23
HP:0012206	HP:0012206	Abnormal sperm motility	0	CCNO CL E G H	10309	18576	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	23
HP:0012206	HP:0012206	Abnormal sperm motility	0	CDC14A CL E G H	8556	1718	OMIM:608653	Deafness, autosomal recessive 32, with or without immotile sperm		2
HP:0012206	HP:0012206	Abnormal sperm motility	0	CEP112 CL E G H	201134	28514	OMIM:619044	SPERMATOGENIC FAILURE 44; SPGF44		1
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP221 CL E G H	200373	33720	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP298 CL E G H	56683	1301	OMIM:615500	Ciliary dyskinesia, primary, 26
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP298 CL E G H	56683	1301	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP300 CL E G H	85016	28188	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP410 CL E G H	755	1260	OMIM:602271	Spondylometaphyseal dysplasia, axial
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP43 CL E G H	80217	26684	OMIM:617592	Spermatogenic failure 19		6
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP45 CL E G H	25790	17229	OMIM:619608	HETEROTAXY, VISCERAL, 11, AUTOSOMAL, WITH MALE INFERTILITY; HTX11
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP47 CL E G H	286464	26708	OMIM:301059	SPERMATOGENIC FAILURE, X-LINKED, 3; SPGFX3		1
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP58 CL E G H	159686	26676	OMIM:619144	SPERMATOGENIC FAILURE 49; SPGF49
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP65 CL E G H	255101	25325	OMIM:618664	SPERMATOGENIC FAILURE 40; SPGF40		1
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP69 CL E G H	79846	26107	OMIM:617959	SPERMATOGENIC FAILURE 24; SPGF24
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP70 CL E G H	118491	30726	OMIM:618670	SPERMATOGENIC FAILURE 41; SPGF41
HP:0012206	HP:0012206	Abnormal sperm motility	0	CFAP91 CL E G H	89876	24010	OMIM:619177	SPERMATOGENIC FAILURE 51; SPGF51
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF1 CL E G H	123872	30539	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	116
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF11 CL E G H	23639	16725	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF2 CL E G H	55172	20188	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	78
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF3 CL E G H	352909	30492	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	63
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF4 CL E G H	161582	21493	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	27
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF5 CL E G H	54919	26013	OMIM:614874	Ciliary dyskinesia, primary, 18		62
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF5 CL E G H	54919	26013	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	62
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAAF6 CL E G H	139212	28570	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH1 CL E G H	25981	2940	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	21
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH10 CL E G H	196385	2941	OMIM:619515	SPERMATOGENIC FAILURE 56; SPGF56		18
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH11 CL E G H	8701	2942	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	542
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH17 CL E G H	8632	2946	OMIM:618643	SPERMATOGENIC FAILURE 39; SPGF39		37
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH2 CL E G H	146754	2948	OMIM:619094	SPERMATOGENIC FAILURE 45; SPGF45		15
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH5 CL E G H	1767	2950	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	527
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH8 CL E G H	1769	2952	OMIM:619095	SPERMATOGENIC FAILURE 46; SPGF46		153
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAH9 CL E G H	1770	2953	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	18
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAI1 CL E G H	27019	2954	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	73
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAI2 CL E G H	64446	18744	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	104
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAJB11 CL E G H	51726	14889	ORPHA:730	Autosomal dominant polycystic kidney disease
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAJB13 CL E G H	374407	30718	OMIM:617091	CILIARY DYSKINESIA, PRIMARY, 34; CILD34		2
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAJB13 CL E G H	374407	30718	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	2
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNAL1 CL E G H	83544	23247	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	167
HP:0012206	HP:0012206	Abnormal sperm motility	0	DNHD1 CL E G H	144132	26532	OMIM:619712	SPERMATOGENIC FAILURE 65; SPGF65
HP:0012206	HP:0012206	Abnormal sperm motility	0	DRC1 CL E G H	92749	24245	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	44
HP:0012206	HP:0012206	Abnormal sperm motility	0	DZIP1 CL E G H	22873	20908	OMIM:619102	SPERMATOGENIC FAILURE 47; SPGF47
HP:0012206	HP:0012206	Abnormal sperm motility	0	FBXO43 CL E G H	286151	28521	OMIM:619696	SPERMATOGENIC FAILURE 64; SPGF64
HP:0012206	HP:0012206	Abnormal sperm motility	0	FOXJ1 CL E G H	2302	3816	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	GANAB CL E G H	23193	4138	ORPHA:730	Autosomal dominant polycystic kidney disease		6
HP:0012206	HP:0012206	Abnormal sperm motility	0	GAS2L2 CL E G H	246176	24846	OMIM:618449	Ciliary dyskinesia, primary, 41		1
HP:0012206	HP:0012206	Abnormal sperm motility	0	GAS2L2 CL E G H	246176	24846	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	1
HP:0012206	HP:0012206	Abnormal sperm motility	0	GAS8 CL E G H	2622	4166	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	9
HP:0012206	HP:0012206	Abnormal sperm motility	0	GBA2 CL E G H	57704	18986	ORPHA:320391	Autosomal recessive spastic paraplegia type 46		30
HP:0012206	HP:0012206	Abnormal sperm motility	0	HNF1B CL E G H	6928	11630	OMIM:137920	Renal cysts and diabetes syndrome		90
HP:0012206	HP:0012206	Abnormal sperm motility	0	HYDIN CL E G H	54768	19368	OMIM:608647	Ciliary dyskinesia, primary, 5		21
HP:0012206	HP:0012206	Abnormal sperm motility	0	HYDIN CL E G H	54768	19368	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	21
HP:0012206	HP:0012206	Abnormal sperm motility	0	IFT140 CL E G H	9742	29077	ORPHA:730	Autosomal dominant polycystic kidney disease		148
HP:0012206	HP:0012206	Abnormal sperm motility	0	IFT74 CL E G H	80173	21424	OMIM:619585	SPERMATOGENIC FAILURE 58; SPGF58		3
HP:0012206	HP:0012206	Abnormal sperm motility	0	KLHL10 CL E G H	317719	18829	OMIM:615081	SPERMATOGENIC FAILURE 11; SPGF11		3
HP:0012206	HP:0012206	Abnormal sperm motility	0	LRRC56 CL E G H	115399	25430	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	MCIDAS CL E G H	345643	40050	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	13
HP:0012206	HP:0012206	Abnormal sperm motility	0	NEK10 CL E G H	152110	18592	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	NME8 CL E G H	51314	16473	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	50
HP:0012206	HP:0012206	Abnormal sperm motility	0	ODAD1 CL E G H	93233	26560	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	ODAD2 CL E G H	55130	25583	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	ODAD3 CL E G H	115948	28303	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	ODAD4 CL E G H	83538	25280	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	OFD1 CL E G H	8481	2567	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	201
HP:0012206	HP:0012206	Abnormal sperm motility	0	PDE11A CL E G H	50940	8773	ORPHA:1359	Carney complex		13
HP:0012206	HP:0012206	Abnormal sperm motility	0	PDHA2 CL E G H	5161	8807	OMIM:619828	SPERMATOGENIC FAILURE 70; SPGF70
HP:0012206	HP:0012206	Abnormal sperm motility	0	PKD1 CL E G H	5310	9008	ORPHA:730	Autosomal dominant polycystic kidney disease		342
HP:0012206	HP:0012206	Abnormal sperm motility	0	PKD2 CL E G H	5311	9009	ORPHA:730	Autosomal dominant polycystic kidney disease		106
HP:0012206	HP:0012206	Abnormal sperm motility	0	PMFBP1 CL E G H	83449	17728	ORPHA:529970	Male infertility due to acephalic spermatozoa
HP:0012206	HP:0012206	Abnormal sperm motility	0	PRKAR1A CL E G H	5573	9388	ORPHA:1359	Carney complex		134
HP:0012206	HP:0012206	Abnormal sperm motility	0	RPGR CL E G H	6103	10295	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	200
HP:0012206	HP:0012206	Abnormal sperm motility	0	RPL10L CL E G H	140801	17976	OMIM:619689	SPERMATOGENIC FAILURE 63; SPGF63		2
HP:0012206	HP:0012206	Abnormal sperm motility	0	RSPH1 CL E G H	89765	12371	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	31
HP:0012206	HP:0012206	Abnormal sperm motility	0	RSPH3 CL E G H	83861	21054	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	5
HP:0012206	HP:0012206	Abnormal sperm motility	0	RSPH4A CL E G H	345895	21558	OMIM:612649	Ciliary dyskinesia, primary, 11		58
HP:0012206	HP:0012206	Abnormal sperm motility	0	RSPH4A CL E G H	345895	21558	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	58
HP:0012206	HP:0012206	Abnormal sperm motility	0	RSPH9 CL E G H	221421	21057	OMIM:612650	CILIARY DYSKINESIA, PRIMARY, 12; CILD12		20
HP:0012206	HP:0012206	Abnormal sperm motility	0	RSPH9 CL E G H	221421	21057	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	20
HP:0012206	HP:0012206	Abnormal sperm motility	0	SLC26A8 CL E G H	116369	14468	OMIM:606766	Spermatogenic failure 3		3
HP:0012206	HP:0012206	Abnormal sperm motility	0	SPAG1 CL E G H	6674	11212	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	45
HP:0012206	HP:0012206	Abnormal sperm motility	0	SPAG17 CL E G H	200162	26620	OMIM:619380	SPERMATOGENIC FAILURE 55; SPGF55		2
HP:0012206	HP:0012206	Abnormal sperm motility	0	SPEF2 CL E G H	79925	26293	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	15
HP:0012206	HP:0012206	Abnormal sperm motility	0	SPEF2 CL E G H	79925	26293	OMIM:618751	SPERMATOGENIC FAILURE 43; SPGF43		15
HP:0012206	HP:0012206	Abnormal sperm motility	0	STK36 CL E G H	27148	17209	OMIM:619436	CILIARY DYSKINESIA, PRIMARY, 46; CILD46		3
HP:0012206	HP:0012206	Abnormal sperm motility	0	STK36 CL E G H	27148	17209	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	3
HP:0012206	HP:0012206	Abnormal sperm motility	0	STRC CL E G H	161497	16035	OMIM:611102	Deafness, sensorineural, and male infertility		78
HP:0012206	HP:0012206	Abnormal sperm motility	0	STRC CL E G H	161497	16035	OMIM:612997	Spermatogenic failure 7		78
HP:0012206	HP:0012206	Abnormal sperm motility	0	SUN5 CL E G H	140732	16252	ORPHA:529970	Male infertility due to acephalic spermatozoa		6
HP:0012206	HP:0012206	Abnormal sperm motility	0	SUN5 CL E G H	140732	16252	OMIM:617187	Spermatogenic failure 16		6
HP:0012206	HP:0012206	Abnormal sperm motility	0	TTC12 CL E G H	54970	23700	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent
HP:0012206	HP:0012206	Abnormal sperm motility	0	TTC21A CL E G H	199223	30761	OMIM:618429	Spermatogenic failure 37
HP:0012206	HP:0012206	Abnormal sperm motility	0	TTC29 CL E G H	83894	29936	OMIM:618745	SPERMATOGENIC FAILURE 42; SPGF42
HP:0012206	HP:0012206	Abnormal sperm motility	0	WDR19 CL E G H	57728	18340	OMIM:619867			95
HP:0012206	HP:0012206	Abnormal sperm motility	0	ZMYND10 CL E G H	51364	19412	OMIM:615444	Ciliary dyskinesia, primary, 22		20
HP:0012206	HP:0012206	Abnormal sperm motility	0	ZMYND10 CL E G H	51364	19412	ORPHA:244	Primary ciliary dyskinesia	HP:0040282 - Frequent	20
HP:0012206	HP:0012207	Reduced sperm motility	1	ALG5 CL E G H	29880	20266	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional
HP:0012206	HP:0012207	Reduced sperm motility	1	ALG9 CL E G H	79796	15672	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional	93
HP:0012206	HP:0012207	Reduced sperm motility	1	ARMC2 CL E G H	84071	23045	OMIM:618433	SPERMATOGENIC FAILURE 38; SPGF38
HP:0012206	HP:0012207	Reduced sperm motility	1	BICC1 CL E G H	80114	19351	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional	5
HP:0012206	HP:0012207	Reduced sperm motility	1	BRDT CL E G H	676	1105	OMIM:617644	Spermatogenic failure 21	.	1
HP:0012206	HP:0012207	Reduced sperm motility	1	CATIP CL E G H	375307	25062	OMIM:619379	SPERMATOGENIC FAILURE 54; SPGF54
HP:0012206	HP:0012207	Reduced sperm motility	1	CATSPER1 CL E G H	117144	17116	OMIM:612997	Spermatogenic failure 7	.	45
HP:0012206	HP:0012208	Immotile sperm	1	CATSPER1 CL E G H	117144	17116	OMIM:612997	Spermatogenic failure 7	.	45
HP:0012206	HP:0012207	Reduced sperm motility	1	CATSPER2 CL E G H	117155	18810	OMIM:611102	Deafness, sensorineural, and male infertility	.	12
HP:0012206	HP:0012208	Immotile sperm	1	CATSPER2 CL E G H	117155	18810	OMIM:612997	Spermatogenic failure 7	.	12
HP:0012206	HP:0012207	Reduced sperm motility	1	CATSPER2 CL E G H	117155	18810	OMIM:612997	Spermatogenic failure 7	.	12
HP:0012206	HP:0012207	Reduced sperm motility	1	CCDC34 CL E G H	91057	25079	OMIM:620084
HP:0012206	HP:0012208	Immotile sperm	1	CCDC39 CL E G H	339829	25244	OMIM:613807	Ciliary dyskinesia, primary, 14		126
HP:0012206	HP:0012207	Reduced sperm motility	1	CCDC39 CL E G H	339829	25244	OMIM:613807	Ciliary dyskinesia, primary, 14		126
HP:0012206	HP:0012208	Immotile sperm	1	CCDC40 CL E G H	55036	26090	OMIM:613808	CILIARY DYSKINESIA, PRIMARY, 15; CILD15		182
HP:0012206	HP:0012208	Immotile sperm	1	CDC14A CL E G H	8556	1718	OMIM:608653	Deafness, autosomal recessive 32, with or without immotile sperm		2
HP:0012206	HP:0012207	Reduced sperm motility	1	CEP112 CL E G H	201134	28514	OMIM:619044	SPERMATOGENIC FAILURE 44; SPGF44		1
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP298 CL E G H	56683	1301	OMIM:615500	Ciliary dyskinesia, primary, 26	.
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP410 CL E G H	755	1260	OMIM:602271	Spondylometaphyseal dysplasia, axial	.
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP43 CL E G H	80217	26684	OMIM:617592	Spermatogenic failure 19		6
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	CFAP45 CL E G H	25790	17229	OMIM:619608	HETEROTAXY, VISCERAL, 11, AUTOSOMAL, WITH MALE INFERTILITY; HTX11
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP47 CL E G H	286464	26708	OMIM:301059	SPERMATOGENIC FAILURE, X-LINKED, 3; SPGFX3		1
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP58 CL E G H	159686	26676	OMIM:619144	SPERMATOGENIC FAILURE 49; SPGF49
HP:0012206	HP:0012208	Immotile sperm	1	CFAP65 CL E G H	255101	25325	OMIM:618664	SPERMATOGENIC FAILURE 40; SPGF40		1
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP69 CL E G H	79846	26107	OMIM:617959	SPERMATOGENIC FAILURE 24; SPGF24
HP:0012206	HP:0012208	Immotile sperm	1	CFAP70 CL E G H	118491	30726	OMIM:618670	SPERMATOGENIC FAILURE 41; SPGF41
HP:0012206	HP:0012207	Reduced sperm motility	1	CFAP91 CL E G H	89876	24010	OMIM:619177	SPERMATOGENIC FAILURE 51; SPGF51
HP:0012206	HP:0012208	Immotile sperm	1	DNAAF5 CL E G H	54919	26013	OMIM:614874	Ciliary dyskinesia, primary, 18	.	62
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	DNAH10 CL E G H	196385	2941	OMIM:619515	SPERMATOGENIC FAILURE 56; SPGF56		18
HP:0012206	HP:0012207	Reduced sperm motility	1	DNAH10 CL E G H	196385	2941	OMIM:619515	SPERMATOGENIC FAILURE 56; SPGF56		18
HP:0012206	HP:0012207	Reduced sperm motility	1	DNAH17 CL E G H	8632	2946	OMIM:618643	SPERMATOGENIC FAILURE 39; SPGF39		37
HP:0012206	HP:0012207	Reduced sperm motility	1	DNAH2 CL E G H	146754	2948	OMIM:619094	SPERMATOGENIC FAILURE 45; SPGF45		15
HP:0012206	HP:0012207	Reduced sperm motility	1	DNAH8 CL E G H	1769	2952	OMIM:619095	SPERMATOGENIC FAILURE 46; SPGF46		153
HP:0012206	HP:0012207	Reduced sperm motility	1	DNAJB11 CL E G H	51726	14889	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional
HP:0012206	HP:0012208	Immotile sperm	1	DNAJB13 CL E G H	374407	30718	OMIM:617091	CILIARY DYSKINESIA, PRIMARY, 34; CILD34		2
HP:0012206	HP:0012207	Reduced sperm motility	1	DNHD1 CL E G H	144132	26532	OMIM:619712	SPERMATOGENIC FAILURE 65; SPGF65
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	DNHD1 CL E G H	144132	26532	OMIM:619712	SPERMATOGENIC FAILURE 65; SPGF65
HP:0012206	HP:0012208	Immotile sperm	1	DZIP1 CL E G H	22873	20908	OMIM:619102	SPERMATOGENIC FAILURE 47; SPGF47
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	FBXO43 CL E G H	286151	28521	OMIM:619696	SPERMATOGENIC FAILURE 64; SPGF64
HP:0012206	HP:0012207	Reduced sperm motility	1	GANAB CL E G H	23193	4138	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional	6
HP:0012206	HP:0012208	Immotile sperm	1	GAS2L2 CL E G H	246176	24846	OMIM:618449	Ciliary dyskinesia, primary, 41		1
HP:0012206	HP:0012207	Reduced sperm motility	1	GBA2 CL E G H	57704	18986	ORPHA:320391	Autosomal recessive spastic paraplegia type 46	HP:0040283 - Occasional	30
HP:0012206	HP:0012207	Reduced sperm motility	1	HNF1B CL E G H	6928	11630	OMIM:137920	Renal cysts and diabetes syndrome	.	90
HP:0012206	HP:0012207	Reduced sperm motility	1	HYDIN CL E G H	54768	19368	OMIM:608647	Ciliary dyskinesia, primary, 5		21
HP:0012206	HP:0012207	Reduced sperm motility	1	IFT140 CL E G H	9742	29077	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional	148
HP:0012206	HP:0012208	Immotile sperm	1	IFT74 CL E G H	80173	21424	OMIM:619585	SPERMATOGENIC FAILURE 58; SPGF58		3
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	IFT74 CL E G H	80173	21424	OMIM:619585	SPERMATOGENIC FAILURE 58; SPGF58		3
HP:0012206	HP:0012207	Reduced sperm motility	1	KLHL10 CL E G H	317719	18829	OMIM:615081	SPERMATOGENIC FAILURE 11; SPGF11		3
HP:0012206	HP:0012207	Reduced sperm motility	1	PDHA2 CL E G H	5161	8807	OMIM:619828	SPERMATOGENIC FAILURE 70; SPGF70
HP:0012206	HP:0012207	Reduced sperm motility	1	PKD1 CL E G H	5310	9008	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional	342
HP:0012206	HP:0012207	Reduced sperm motility	1	PKD2 CL E G H	5311	9009	ORPHA:730	Autosomal dominant polycystic kidney disease	HP:0040283 - Occasional	106
HP:0012206	HP:0012207	Reduced sperm motility	1	PMFBP1 CL E G H	83449	17728	ORPHA:529970	Male infertility due to acephalic spermatozoa	HP:0040282 - Frequent
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	RPL10L CL E G H	140801	17976	OMIM:619689	SPERMATOGENIC FAILURE 63; SPGF63		2
HP:0012206	HP:0012207	Reduced sperm motility	1	RSPH4A CL E G H	345895	21558	OMIM:612649	Ciliary dyskinesia, primary, 11		58
HP:0012206	HP:0012207	Reduced sperm motility	1	RSPH9 CL E G H	221421	21057	OMIM:612650	CILIARY DYSKINESIA, PRIMARY, 12; CILD12		20
HP:0012206	HP:0012208	Immotile sperm	1	RSPH9 CL E G H	221421	21057	OMIM:612650	CILIARY DYSKINESIA, PRIMARY, 12; CILD12		20
HP:0012206	HP:0012207	Reduced sperm motility	1	SLC26A8 CL E G H	116369	14468	OMIM:606766	Spermatogenic failure 3		3
HP:0012206	HP:0012207	Reduced sperm motility	1	SPAG17 CL E G H	200162	26620	OMIM:619380	SPERMATOGENIC FAILURE 55; SPGF55		2
HP:0012206	HP:0012207	Reduced sperm motility	1	SPEF2 CL E G H	79925	26293	OMIM:618751	SPERMATOGENIC FAILURE 43; SPGF43		15
HP:0012206	HP:0012207	Reduced sperm motility	1	STK36 CL E G H	27148	17209	OMIM:619436	CILIARY DYSKINESIA, PRIMARY, 46; CILD46		3
HP:0012206	HP:0012207	Reduced sperm motility	1	STRC CL E G H	161497	16035	OMIM:611102	Deafness, sensorineural, and male infertility	.	78
HP:0012206	HP:0012208	Immotile sperm	1	STRC CL E G H	161497	16035	OMIM:612997	Spermatogenic failure 7	.	78
HP:0012206	HP:0012207	Reduced sperm motility	1	STRC CL E G H	161497	16035	OMIM:612997	Spermatogenic failure 7	.	78
HP:0012206	HP:0012207	Reduced sperm motility	1	SUN5 CL E G H	140732	16252	ORPHA:529970	Male infertility due to acephalic spermatozoa	HP:0040282 - Frequent	6
HP:0012206	HP:0012207	Reduced sperm motility	1	SUN5 CL E G H	140732	16252	OMIM:617187	Spermatogenic failure 16	.	6
HP:0012206	HP:0012207	Reduced sperm motility	1	TTC21A CL E G H	199223	30761	OMIM:618429	Spermatogenic failure 37
HP:0012206	HP:0012207	Reduced sperm motility	1	TTC29 CL E G H	83894	29936	OMIM:618745	SPERMATOGENIC FAILURE 42; SPGF42
HP:0012206	HP:0034011	Reduced progressive sperm motility	1	WDR19 CL E G H	57728	18340	OMIM:619867			95
HP:0012206	HP:0012207	Reduced sperm motility	1	ZMYND10 CL E G H	51364	19412	OMIM:615444	Ciliary dyskinesia, primary, 22	.	20

Genes (95) :ALG5 ALG9 ARMC2 BICC1 BRDT CATIP CATSPER1 CATSPER2 CCDC103 CCDC34 CCDC39 CCDC40 CCDC65 CCNO CDC14A CEP112 CFAP221 CFAP298 CFAP300 CFAP410 CFAP43 CFAP45 CFAP47 CFAP58 CFAP65 CFAP69 CFAP70 CFAP91 DNAAF1 DNAAF11 DNAAF2 DNAAF3 DNAAF4 DNAAF5 DNAAF6 DNAH1 DNAH10 DNAH11 DNAH17 DNAH2 DNAH5 DNAH8 DNAH9 DNAI1 DNAI2 DNAJB11 DNAJB13 DNAL1 DNHD1 DRC1 DZIP1 FBXO43 FOXJ1 GANAB GAS2L2 GAS8 GBA2 HNF1B HYDIN IFT140 IFT74 KLHL10 LRRC56 MCIDAS NEK10 NME8 ODAD1 ODAD2 ODAD3 ODAD4 OFD1 PDE11A PDHA2 PKD1 PKD2 PMFBP1 PRKAR1A RPGR RPL10L RSPH1 RSPH3 RSPH4A RSPH9 SLC26A8 SPAG1 SPAG17 SPEF2 STK36 STRC SUN5 TTC12 TTC21A TTC29 WDR19 ZMYND10

Diseases (52) :ORPHA:730 OMIM:618433 OMIM:617644 OMIM:619379 OMIM:612997 OMIM:611102 ORPHA:244 OMIM:620084 OMIM:613807 OMIM:613808 OMIM:608653 OMIM:619044 OMIM:615500 OMIM:602271 OMIM:617592 OMIM:619608 OMIM:301059 OMIM:619144 OMIM:618664 OMIM:617959 OMIM:618670 OMIM:619177 OMIM:614874 OMIM:619515 OMIM:618643 OMIM:619094 OMIM:619095 OMIM:617091 OMIM:619712 OMIM:619102 OMIM:619696 OMIM:618449 ORPHA:320391 OMIM:137920 OMIM:608647 OMIM:619585 OMIM:615081 ORPHA:1359 OMIM:619828 ORPHA:529970 OMIM:619689 OMIM:612649 OMIM:612650 OMIM:606766 OMIM:619380 OMIM:618751 OMIM:619436 OMIM:617187 OMIM:618429 OMIM:618745 OMIM:619867 OMIM:615444

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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