Human Phenotype Ontology 
Grandparent Node:
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Hyperreflexia (HP:0001347)help
Grandparent Node:
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Involuntary movements (HP:0004305)help
Parent Node:
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Clonus (HP:0002169)help
..Starting node
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Knee clonus (HP:0011449)help
Term ID: 11449
Name: Knee clonus
Synonym: Patellar clonus
Definition: Clonus is an involuntary tendon reflex that causes repeated flexion and extension of the foot. Knee clonus can be tested by rapidly pushing the patella towards the toes.
Comments:
Reference: HP:0011449
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAnkle clonus (HP:0011448) help
..expandElbow clonus (HP:0011728) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0011449HP:0011449Knee clonus0GBA2 CL E G H57704614409Spastic paraplegia 46, autosomal recessive614409C2828721OMIM127718986609471
HP:0011449HP:0011449Knee clonus0KIF5A CL E G H3798604187Spastic paraplegia 10604187C1858712OMIM17446323602821
HP:0011449HP:0011449Knee clonus0RTN2 CL E G H6253604805Spastic paraplegia 12604805C1858106OMIM118410468603183
HP:0011449HP:0011449Knee clonus0SLC52A3 CL E G H113278211530Brown-Vialetto-Van Laere syndrome 1211530CN029849OMIM139916187613350
HP:0011449HP:0011449Knee clonus0SPART CL E G H23111275900Troyer syndrome275900C0393559OMIM127418514607111
HP:0011449HP:0011449Knee clonus0SPG11 CL E G H80208604360Spastic paraplegia 11, autosomal recessive604360C1858479OMIM1216511226610844
 
HPO disease - gene - phenotype less frequent non-typical associations:


Genes (6) :GBA2 KIF5A RTN2 SLC52A3 SPART SPG11

Diseases (6) :614409 604187 604805 211530 275900 604360
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.