CCAM; Congenital cystic adenomatoid malformation of the lung; Congenital cystic disease of the lung; Cystic adenomatoid lung disease
Definition:
Congenital pulmonary airway malformation (CPAM) - previously known as congenital cystic adenomatoid malformation (CCAM) - is a relatively rare developmental malformation of the lower respiratory tract. It is a hamartomatous, dysplastic developmental abnormality of the lung characterized by abnormal airway patterning during lung branching morphogenesis and is formed by abnormal branching of the immature bronchioles.