Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of the skull base (HP:0002693)help
Parent Node:
expandAbnormal posterior cranial fossa morphology (HP:0000932)help
..Starting node
..expandAbnormality of the clivus (HP:0010558)help
Term ID: 10558
Name: Abnormality of the clivus
Synonym:
Definition: An abnormality of the clivus, which is the inclined bony region of the posterior cranial fossa located between the sella turcica and the foramen magnum.
Comments:
Reference: HP:0010558
Genes and Diseases:
 
       Child Nodes:
........expandVertical clivus (HP:0010559) help

 Sister Nodes: 
..expandBasilar impression (HP:0005758) help
..expandBasilar invagination (HP:0012366) help
..expandEnlarged posterior fossa (HP:0005445) help
..expandFlat posterior fossa (HP:0040011) help
..expandPosterior fossa cyst (HP:0007291) help
..expandSmall posterior fossa (HP:0040010) help
..expandThinning and bulging of the posterior fossa bones (HP:0000931) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0010558HP:0010558Abnormality of the clivus0DKK1 CL E G H229432891ORPHA:268882Arnold-Chiari malformation type IHP:0040282 - Frequent
HP:0010558HP:0010558Abnormality of the clivus0FLNA CL E G H23163754OMIM:304120Otopalatodigital syndrome, type II493
HP:0010558HP:0010558Abnormality of the clivus0ZSWIM6 CL E G H5768829316OMIM:603671Acromelic frontonasal dysostosis5
HP:0010558HP:0010559Vertical clivus1FLNA CL E G H23163754OMIM:304120Otopalatodigital syndrome, type II.493
HP:0010558HP:0010559Vertical clivus1ZSWIM6 CL E G H5768829316OMIM:603671Acromelic frontonasal dysostosisHP:0040283 - Occasional5


Genes (3) :DKK1 FLNA ZSWIM6

Diseases (3) :ORPHA:268882 OMIM:304120 OMIM:603671
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.