Human Phenotype Ontology

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0010051	HP:0010051	Deviation of the hallux	0	ACVR1 CL E G H	90	171	OMIM:135100	Fibrodysplasia ossificans progressiva		49
HP:0010051	HP:0010051	Deviation of the hallux	0	ACVR1 CL E G H	90	171	ORPHA:337	Fibrodysplasia ossificans progressiva		49
HP:0010051	HP:0010051	Deviation of the hallux	0	AEBP1 CL E G H	165	303	ORPHA:536532	Classical-like Ehlers-Danlos syndrome type 2
HP:0010051	HP:0010051	Deviation of the hallux	0	AEBP1 CL E G H	165	303	OMIM:618000	Ehlers-Danlos syndrome, classic-like, 2
HP:0010051	HP:0010051	Deviation of the hallux	0	AKT1 CL E G H	207	391	ORPHA:744	Proteus syndrome		54
HP:0010051	HP:0010051	Deviation of the hallux	0	ATL3 CL E G H	25923	24526	OMIM:615632	Neuropathy, hereditary sensory, type IF		5
HP:0010051	HP:0010051	Deviation of the hallux	0	ATP6V1B2 CL E G H	526	854	ORPHA:3473	Zimmermann-Laband syndrome		5
HP:0010051	HP:0010051	Deviation of the hallux	0	B3GALT6 CL E G H	126792	17978	ORPHA:536467	B3GALT6-related spondylodysplastic Ehlers-Danlos syndrome		38
HP:0010051	HP:0010051	Deviation of the hallux	0	B3GALT6 CL E G H	126792	17978	OMIM:271640	Spondyloepimetaphyseal dysplasia with joint laxity, type 1, with or without fractures		38
HP:0010051	HP:0010051	Deviation of the hallux	0	B3GAT3 CL E G H	26229	923	OMIM:245600	Multiple joint dislocations, short stature, craniofacial dysmorphism, with or without congenital heart defects		5
HP:0010051	HP:0010051	Deviation of the hallux	0	BAZ1B CL E G H	9031	961	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	BCL7B CL E G H	9275	1005	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	BMP2 CL E G H	650	1069	OMIM:112600	Brachydactyly, type A2		13
HP:0010051	HP:0010051	Deviation of the hallux	0	BMPR1B CL E G H	658	1077	OMIM:112600	Brachydactyly, type A2		90
HP:0010051	HP:0010051	Deviation of the hallux	0	BUD23 CL E G H	114049	16405	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	C2CD3 CL E G H	26005	24564	ORPHA:434179	Orofaciodigital syndrome type 14	HP:0040282 - Frequent	27
HP:0010051	HP:0010051	Deviation of the hallux	0	CDKL5 CL E G H	6792	11411	ORPHA:505652	CDKL5-deficiency disorder		405
HP:0010051	HP:0010051	Deviation of the hallux	0	CHST11 CL E G H	50515	17422	OMIM:618167	Osteochondrodysplasia, brachydactyly, and overlapping malformed digits		1
HP:0010051	HP:0010051	Deviation of the hallux	0	CHST3 CL E G H	9469	1971	OMIM:245600	Multiple joint dislocations, short stature, craniofacial dysmorphism, with or without congenital heart defects		165
HP:0010051	HP:0010051	Deviation of the hallux	0	CLIP2 CL E G H	7461	2586	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	COL1A2 CL E G H	1278	2198	ORPHA:230851	Cardiac-valvular Ehlers-Danlos syndrome		243
HP:0010051	HP:0010051	Deviation of the hallux	0	COL1A2 CL E G H	1278	2198	OMIM:617821	Ehlers-Danlos syndrome, arthrochalasia type, 2		243
HP:0010051	HP:0010051	Deviation of the hallux	0	CREBBP CL E G H	1387	2348	ORPHA:353277	Rubinstein-Taybi syndrome due to CREBBP mutations	HP:0040283 - Occasional	291
HP:0010051	HP:0010051	Deviation of the hallux	0	CWC27 CL E G H	10283	10664	ORPHA:166035	Brachydactyly-short stature-retinitis pigmentosa syndrome		4
HP:0010051	HP:0010051	Deviation of the hallux	0	DNAJC30 CL E G H	84277	16410	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	DYRK1A CL E G H	1859	3091	ORPHA:268261	DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion		134
HP:0010051	HP:0010051	Deviation of the hallux	0	DYRK1A CL E G H	1859	3091	OMIM:614104	Mental retardation, autosomal dominant 7		134
HP:0010051	HP:0010051	Deviation of the hallux	0	EIF4H CL E G H	7458	12741	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	ELN CL E G H	2006	3327	ORPHA:904	Williams syndrome		172
HP:0010051	HP:0010051	Deviation of the hallux	0	ELN CL E G H	2006	3327	OMIM:194050	Williams-Beuren syndrome		172
HP:0010051	HP:0010051	Deviation of the hallux	0	EP300 CL E G H	2033	3373	ORPHA:353284	Rubinstein-Taybi syndrome due to EP300 haploinsufficiency	HP:0040283 - Occasional	250
HP:0010051	HP:0010051	Deviation of the hallux	0	ERF CL E G H	2077	3444	OMIM:617180	Chitayat syndrome		12
HP:0010051	HP:0010051	Deviation of the hallux	0	ERMARD CL E G H	55780	21056	ORPHA:75857	6q terminal deletion syndrome		36
HP:0010051	HP:0010051	Deviation of the hallux	0	FGF9 CL E G H	2254	3687	OMIM:612961	Multiple synostoses syndrome 3		75
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR1 CL E G H	2260	3688	OMIM:123150	Jackson-Weiss syndrome		172
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR1 CL E G H	2260	3688	ORPHA:93258	Pfeiffer syndrome type 1		172
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR2 CL E G H	2263	3689	OMIM:123150	Jackson-Weiss syndrome		175
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR2 CL E G H	2263	3689	ORPHA:93258	Pfeiffer syndrome type 1		175
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR2 CL E G H	2263	3689	ORPHA:93259	Pfeiffer syndrome type 2		175
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR2 CL E G H	2263	3689	ORPHA:93260	Pfeiffer syndrome type 3		175
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR2 CL E G H	2263	3689	OMIM:101400	Saethre-Chotzen syndrome		175
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR2 CL E G H	2263	3689	ORPHA:794	Saethre-Chotzen syndrome		175
HP:0010051	HP:0010051	Deviation of the hallux	0	FGFR3 CL E G H	2261	3690	ORPHA:794	Saethre-Chotzen syndrome		145
HP:0010051	HP:0010051	Deviation of the hallux	0	FHL1 CL E G H	2273	3702	OMIM:300280	Uruguay faciocardiomusculoskeletal syndrome		68
HP:0010051	HP:0010051	Deviation of the hallux	0	FKBP6 CL E G H	8468	3722	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	GBA1 CL E G H	2629	4177	ORPHA:2072	Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	GDF5 CL E G H	8200	4220	OMIM:112600	Brachydactyly, type A2		52
HP:0010051	HP:0010051	Deviation of the hallux	0	GTF2I CL E G H	2969	4659	ORPHA:904	Williams syndrome		1
HP:0010051	HP:0010051	Deviation of the hallux	0	GTF2IRD1 CL E G H	9569	4661	ORPHA:904	Williams syndrome		1
HP:0010051	HP:0010051	Deviation of the hallux	0	GTF2IRD2 CL E G H	84163	30775	ORPHA:904	Williams syndrome		1
HP:0010051	HP:0010051	Deviation of the hallux	0	H4C9 CL E G H	8294	4793	OMIM:619951
HP:0010051	HP:0010051	Deviation of the hallux	0	HEATR3 CL E G H	55027	26087	OMIM:620072
HP:0010051	HP:0010051	Deviation of the hallux	0	HOXA13 CL E G H	3209	5102	OMIM:140000	Hand-Foot-Genital syndrome		11
HP:0010051	HP:0010051	Deviation of the hallux	0	HOXA13 CL E G H	3209	5102	ORPHA:2438	Hand-foot-genital syndrome		11
HP:0010051	HP:0010051	Deviation of the hallux	0	HOXD13 CL E G H	3239	5136	ORPHA:93409	Brachydactyly-syndactyly, Zhao type		25
HP:0010051	HP:0010051	Deviation of the hallux	0	IL11RA CL E G H	3590	5967	OMIM:614188	Craniosynostosis and dental anomalies		8
HP:0010051	HP:0010051	Deviation of the hallux	0	ITCH CL E G H	83737	13890	OMIM:613385	AUTOIMMUNE DISEASE, MULTISYSTEM, WITH FACIAL DYSMORPHISM; ADMFD		3
HP:0010051	HP:0010051	Deviation of the hallux	0	KAT6A CL E G H	7994	13013	OMIM:616268	Arboleda-Tham syndrome		34
HP:0010051	HP:0010051	Deviation of the hallux	0	KCNH1 CL E G H	3756	6250	ORPHA:3473	Zimmermann-Laband syndrome		13
HP:0010051	HP:0010051	Deviation of the hallux	0	KCNN3 CL E G H	3782	6292	ORPHA:3473	Zimmermann-Laband syndrome		7
HP:0010051	HP:0010051	Deviation of the hallux	0	LIMK1 CL E G H	3984	6613	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	METTL27 CL E G H	155368	19068	ORPHA:904	Williams syndrome		1
HP:0010051	HP:0010051	Deviation of the hallux	0	MLXIPL CL E G H	51085	12744	ORPHA:904	Williams syndrome		1
HP:0010051	HP:0010051	Deviation of the hallux	0	MLXIPL CL E G H	51085	12744	OMIM:194050	Williams-Beuren syndrome		1
HP:0010051	HP:0010051	Deviation of the hallux	0	MYH3 CL E G H	4621	7573	OMIM:618436	Arthrogryposis, distal, type 2B3		166
HP:0010051	HP:0010051	Deviation of the hallux	0	NCF1 CL E G H	653361	7660	ORPHA:904	Williams syndrome		13
HP:0010051	HP:0010051	Deviation of the hallux	0	NFIX CL E G H	4784	7788	OMIM:602535	Marshall-Smith syndrome		40
HP:0010051	HP:0010051	Deviation of the hallux	0	NONO CL E G H	4841	7871	ORPHA:466791	Macrocephaly-intellectual disability-left ventricular non compaction syndrome		10
HP:0010051	HP:0010051	Deviation of the hallux	0	NONO CL E G H	4841	7871	OMIM:300967	MENTAL RETARDATION, X-LINKED, SYNDROMIC 34; MRXS34		10
HP:0010051	HP:0010051	Deviation of the hallux	0	NUP107 CL E G H	57122	29914	OMIM:618348	Galloway-Mowat syndrome 7		5
HP:0010051	HP:0010051	Deviation of the hallux	0	PCDHGC4 CL E G H	56098	8717	OMIM:619880
HP:0010051	HP:0010051	Deviation of the hallux	0	PRDM5 CL E G H	11107	9349	ORPHA:90354	Brittle cornea syndrome		58
HP:0010051	HP:0010051	Deviation of the hallux	0	PSMB8 CL E G H	5696	9545	OMIM:256040	Proteasome-associated autoinflammatory syndrome 1 and digenic forms		20
HP:0010051	HP:0010051	Deviation of the hallux	0	PTEN CL E G H	5728	9588	ORPHA:744	Proteus syndrome		948
HP:0010051	HP:0010051	Deviation of the hallux	0	RBBP8 CL E G H	5932	9891	OMIM:251255	Jawad syndrome		68
HP:0010051	HP:0010051	Deviation of the hallux	0	RFC2 CL E G H	5982	9970	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	SCARF2 CL E G H	91179	19869	OMIM:600920	Van den Ende-Gupta syndrome		11
HP:0010051	HP:0010051	Deviation of the hallux	0	SF3B4 CL E G H	10262	10771	OMIM:154400	Acrofacial dysostosis 1, Nager type		49
HP:0010051	HP:0010051	Deviation of the hallux	0	SLC16A2 CL E G H	6567	10923	OMIM:300523	Allan-Herndon-Dudley syndrome		57
HP:0010051	HP:0010051	Deviation of the hallux	0	SLC29A3 CL E G H	55315	23096	ORPHA:168569	H syndrome		68
HP:0010051	HP:0010051	Deviation of the hallux	0	SLC29A3 CL E G H	55315	23096	OMIM:602782	Histiocytosis-lymphadenopathy plus syndrome		68
HP:0010051	HP:0010051	Deviation of the hallux	0	SMARCA2 CL E G H	6595	11098	OMIM:601358	Nicolaides-Baraitser syndrome		146
HP:0010051	HP:0010051	Deviation of the hallux	0	SOX9 CL E G H	6662	11204	OMIM:114290	Campomelic dysplasia		109
HP:0010051	HP:0010051	Deviation of the hallux	0	SRY CL E G H	6736	11311	ORPHA:1772	45,X/46,XY mixed gonadal dysgenesis		23
HP:0010051	HP:0010051	Deviation of the hallux	0	STX1A CL E G H	6804	11433	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	TBC1D2B CL E G H	23102	29183	ORPHA:397973	Intellectual disability-obesity-prognathism-eye and skin anomalies syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	TBL2 CL E G H	26608	11586	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	TCF12 CL E G H	6938	11623	OMIM:615314	Craniosynostosis 3		28
HP:0010051	HP:0010051	Deviation of the hallux	0	TMEM270 CL E G H	135886	23018	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	TP63 CL E G H	8626	15979	OMIM:603543	Limb-Mammary syndrome		140
HP:0010051	HP:0010051	Deviation of the hallux	0	TTI2 CL E G H	80185	26262	OMIM:615541	Mental retardation, autosomal recessive 39		11
HP:0010051	HP:0010051	Deviation of the hallux	0	TWIST1 CL E G H	7291	12428	OMIM:101400	Saethre-Chotzen syndrome		18
HP:0010051	HP:0010051	Deviation of the hallux	0	TWIST1 CL E G H	7291	12428	ORPHA:794	Saethre-Chotzen syndrome		18
HP:0010051	HP:0010051	Deviation of the hallux	0	USP7 CL E G H	7874	12630	OMIM:616863	Chromosome 16p13.2 deletion syndrome		2
HP:0010051	HP:0010051	Deviation of the hallux	0	USP9X CL E G H	8239	12632	ORPHA:480880	X-linked female restricted facial dysmorphism-short stature-choanal atresia-intellectual disability		27
HP:0010051	HP:0010051	Deviation of the hallux	0	VPS37D CL E G H	155382	18287	ORPHA:904	Williams syndrome
HP:0010051	HP:0010051	Deviation of the hallux	0	YY1 CL E G H	7528	12856	ORPHA:506358	Gabriele-de Vries syndrome		7
HP:0010051	HP:0010051	Deviation of the hallux	0	YY1 CL E G H	7528	12856	OMIM:617557	Gabriele-De vries syndrome		7
HP:0010051	HP:0010051	Deviation of the hallux	0	ZEB2 CL E G H	9839	14881	ORPHA:261552	Mowat-Wilson syndrome due to a ZEB2 point mutation		362
HP:0010051	HP:0010051	Deviation of the hallux	0	ZEB2 CL E G H	9839	14881	ORPHA:261537	Mowat-Wilson syndrome due to monosomy 2q22		362
HP:0010051	HP:0010051	Deviation of the hallux	0	ZMIZ1 CL E G H	57178	16493	OMIM:618659	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND DISTAL SKELETAL ANOMALIES; NEDDFSA
HP:0010051	HP:0010051	Deviation of the hallux	0	ZNF469 CL E G H	84627	23216	ORPHA:90354	Brittle cornea syndrome		397
HP:0010051	HP:0040018	Clinodactyly of hallux	1	CL E G H
HP:0010051	HP:0011926	Proximal placement of hallux	1	CL E G H
HP:0010051	HP:0001822	Hallux valgus	1	ACVR1 CL E G H	90	171	ORPHA:337	Fibrodysplasia ossificans progressiva	HP:0040283 - Occasional	49
HP:0010051	HP:0001822	Hallux valgus	1	ACVR1 CL E G H	90	171	OMIM:135100	Fibrodysplasia ossificans progressiva	.	49
HP:0010051	HP:0001822	Hallux valgus	1	AEBP1 CL E G H	165	303	ORPHA:536532	Classical-like Ehlers-Danlos syndrome type 2	HP:0040281 - Very frequent
HP:0010051	HP:0001822	Hallux valgus	1	AEBP1 CL E G H	165	303	OMIM:618000	Ehlers-Danlos syndrome, classic-like, 2	.
HP:0010051	HP:0001822	Hallux valgus	1	AKT1 CL E G H	207	391	ORPHA:744	Proteus syndrome	HP:0040283 - Occasional	54
HP:0010051	HP:0001822	Hallux valgus	1	ATL3 CL E G H	25923	24526	OMIM:615632	Neuropathy, hereditary sensory, type IF	.	5
HP:0010051	HP:0001822	Hallux valgus	1	ATP6V1B2 CL E G H	526	854	ORPHA:3473	Zimmermann-Laband syndrome	HP:0040283 - Occasional	5
HP:0010051	HP:0001822	Hallux valgus	1	B3GALT6 CL E G H	126792	17978	ORPHA:536467	B3GALT6-related spondylodysplastic Ehlers-Danlos syndrome	HP:0040282 - Frequent	38
HP:0010051	HP:0001822	Hallux valgus	1	B3GALT6 CL E G H	126792	17978	OMIM:271640	Spondyloepimetaphyseal dysplasia with joint laxity, type 1, with or without fractures	.	38
HP:0010051	HP:0001822	Hallux valgus	1	B3GAT3 CL E G H	26229	923	OMIM:245600	Multiple joint dislocations, short stature, craniofacial dysmorphism, with or without congenital heart defects		5
HP:0010051	HP:0001822	Hallux valgus	1	BAZ1B CL E G H	9031	961	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	BCL7B CL E G H	9275	1005	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	BMP2 CL E G H	650	1069	OMIM:112600	Brachydactyly, type A2		13
HP:0010051	HP:0001822	Hallux valgus	1	BMPR1B CL E G H	658	1077	OMIM:112600	Brachydactyly, type A2		90
HP:0010051	HP:0001822	Hallux valgus	1	BUD23 CL E G H	114049	16405	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	CDKL5 CL E G H	6792	11411	ORPHA:505652	CDKL5-deficiency disorder	HP:0040283 - Occasional	405
HP:0010051	HP:0001822	Hallux valgus	1	CHST11 CL E G H	50515	17422	OMIM:618167	Osteochondrodysplasia, brachydactyly, and overlapping malformed digits	.	1
HP:0010051	HP:0001822	Hallux valgus	1	CHST3 CL E G H	9469	1971	OMIM:245600	Multiple joint dislocations, short stature, craniofacial dysmorphism, with or without congenital heart defects		165
HP:0010051	HP:0001822	Hallux valgus	1	CLIP2 CL E G H	7461	2586	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	COL1A2 CL E G H	1278	2198	ORPHA:230851	Cardiac-valvular Ehlers-Danlos syndrome	HP:0040282 - Frequent	243
HP:0010051	HP:0001822	Hallux valgus	1	COL1A2 CL E G H	1278	2198	OMIM:617821	Ehlers-Danlos syndrome, arthrochalasia type, 2	.	243
HP:0010051	HP:0001822	Hallux valgus	1	CWC27 CL E G H	10283	10664	ORPHA:166035	Brachydactyly-short stature-retinitis pigmentosa syndrome	HP:0040283 - Occasional	4
HP:0010051	HP:0001822	Hallux valgus	1	DNAJC30 CL E G H	84277	16410	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	DYRK1A CL E G H	1859	3091	ORPHA:268261	DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion	HP:0040283 - Occasional	134
HP:0010051	HP:0001822	Hallux valgus	1	DYRK1A CL E G H	1859	3091	OMIM:614104	Mental retardation, autosomal dominant 7	.	134
HP:0010051	HP:0001822	Hallux valgus	1	EIF4H CL E G H	7458	12741	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	ELN CL E G H	2006	3327	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	172
HP:0010051	HP:0001822	Hallux valgus	1	ELN CL E G H	2006	3327	OMIM:194050	Williams-Beuren syndrome		172
HP:0010051	HP:0001822	Hallux valgus	1	ERF CL E G H	2077	3444	OMIM:617180	Chitayat syndrome		12
HP:0010051	HP:0001822	Hallux valgus	1	ERMARD CL E G H	55780	21056	ORPHA:75857	6q terminal deletion syndrome	HP:0040283 - Occasional	36
HP:0010051	HP:0008080	Hallux varus	1	FGF9 CL E G H	2254	3687	OMIM:612961	Multiple synostoses syndrome 3	HP:0040284 - Very rare	75
HP:0010051	HP:0008080	Hallux varus	1	FGFR1 CL E G H	2260	3688	OMIM:123150	Jackson-Weiss syndrome	.	172
HP:0010051	HP:0008080	Hallux varus	1	FGFR1 CL E G H	2260	3688	ORPHA:93258	Pfeiffer syndrome type 1	HP:0040281 - Very frequent	172
HP:0010051	HP:0008080	Hallux varus	1	FGFR2 CL E G H	2263	3689	OMIM:123150	Jackson-Weiss syndrome	.	175
HP:0010051	HP:0008080	Hallux varus	1	FGFR2 CL E G H	2263	3689	ORPHA:93258	Pfeiffer syndrome type 1	HP:0040281 - Very frequent	175
HP:0010051	HP:0008080	Hallux varus	1	FGFR2 CL E G H	2263	3689	ORPHA:93259	Pfeiffer syndrome type 2	HP:0040281 - Very frequent	175
HP:0010051	HP:0008080	Hallux varus	1	FGFR2 CL E G H	2263	3689	ORPHA:93260	Pfeiffer syndrome type 3	HP:0040281 - Very frequent	175
HP:0010051	HP:0001822	Hallux valgus	1	FGFR2 CL E G H	2263	3689	ORPHA:794	Saethre-Chotzen syndrome	HP:0040283 - Occasional	175
HP:0010051	HP:0001822	Hallux valgus	1	FGFR2 CL E G H	2263	3689	OMIM:101400	Saethre-Chotzen syndrome	.	175
HP:0010051	HP:0001822	Hallux valgus	1	FGFR3 CL E G H	2261	3690	ORPHA:794	Saethre-Chotzen syndrome	HP:0040283 - Occasional	145
HP:0010051	HP:0001822	Hallux valgus	1	FHL1 CL E G H	2273	3702	OMIM:300280	Uruguay faciocardiomusculoskeletal syndrome	.	68
HP:0010051	HP:0001822	Hallux valgus	1	FKBP6 CL E G H	8468	3722	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	GBA1 CL E G H	2629	4177	ORPHA:2072	Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome	HP:0040283 - Occasional
HP:0010051	HP:0001822	Hallux valgus	1	GDF5 CL E G H	8200	4220	OMIM:112600	Brachydactyly, type A2		52
HP:0010051	HP:0001822	Hallux valgus	1	GTF2I CL E G H	2969	4659	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	1
HP:0010051	HP:0001822	Hallux valgus	1	GTF2IRD1 CL E G H	9569	4661	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	1
HP:0010051	HP:0001822	Hallux valgus	1	GTF2IRD2 CL E G H	84163	30775	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	1
HP:0010051	HP:0001822	Hallux valgus	1	H4C9 CL E G H	8294	4793	OMIM:619951
HP:0010051	HP:0001822	Hallux valgus	1	HEATR3 CL E G H	55027	26087	OMIM:620072
HP:0010051	HP:0008080	Hallux varus	1	HOXA13 CL E G H	3209	5102	ORPHA:2438	Hand-foot-genital syndrome	HP:0040282 - Frequent	11
HP:0010051	HP:0008080	Hallux varus	1	HOXA13 CL E G H	3209	5102	OMIM:140000	Hand-Foot-Genital syndrome	.	11
HP:0010051	HP:0001822	Hallux valgus	1	HOXD13 CL E G H	3239	5136	ORPHA:93409	Brachydactyly-syndactyly, Zhao type	HP:0040282 - Frequent	25
HP:0010051	HP:0001822	Hallux valgus	1	IL11RA CL E G H	3590	5967	OMIM:614188	Craniosynostosis and dental anomalies	HP:0040283 - Occasional	8
HP:0010051	HP:0001822	Hallux valgus	1	ITCH CL E G H	83737	13890	OMIM:613385	AUTOIMMUNE DISEASE, MULTISYSTEM, WITH FACIAL DYSMORPHISM; ADMFD		3
HP:0010051	HP:0001822	Hallux valgus	1	KCNH1 CL E G H	3756	6250	ORPHA:3473	Zimmermann-Laband syndrome	HP:0040283 - Occasional	13
HP:0010051	HP:0001822	Hallux valgus	1	KCNN3 CL E G H	3782	6292	ORPHA:3473	Zimmermann-Laband syndrome	HP:0040283 - Occasional	7
HP:0010051	HP:0001822	Hallux valgus	1	LIMK1 CL E G H	3984	6613	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	METTL27 CL E G H	155368	19068	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	1
HP:0010051	HP:0001822	Hallux valgus	1	MLXIPL CL E G H	51085	12744	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	1
HP:0010051	HP:0001822	Hallux valgus	1	MLXIPL CL E G H	51085	12744	OMIM:194050	Williams-Beuren syndrome		1
HP:0010051	HP:0001822	Hallux valgus	1	MYH3 CL E G H	4621	7573	OMIM:618436	Arthrogryposis, distal, type 2B3	.	166
HP:0010051	HP:0001822	Hallux valgus	1	NCF1 CL E G H	653361	7660	ORPHA:904	Williams syndrome	HP:0040282 - Frequent	13
HP:0010051	HP:0001822	Hallux valgus	1	NFIX CL E G H	4784	7788	OMIM:602535	Marshall-Smith syndrome		40
HP:0010051	HP:0001822	Hallux valgus	1	NONO CL E G H	4841	7871	ORPHA:466791	Macrocephaly-intellectual disability-left ventricular non compaction syndrome	HP:0040283 - Occasional	10
HP:0010051	HP:0001822	Hallux valgus	1	NONO CL E G H	4841	7871	OMIM:300967	MENTAL RETARDATION, X-LINKED, SYNDROMIC 34; MRXS34		10
HP:0010051	HP:0001822	Hallux valgus	1	NUP107 CL E G H	57122	29914	OMIM:618348	Galloway-Mowat syndrome 7		5
HP:0010051	HP:0001822	Hallux valgus	1	PCDHGC4 CL E G H	56098	8717	OMIM:619880
HP:0010051	HP:0001822	Hallux valgus	1	PRDM5 CL E G H	11107	9349	ORPHA:90354	Brittle cornea syndrome	HP:0040283 - Occasional	58
HP:0010051	HP:0001822	Hallux valgus	1	PSMB8 CL E G H	5696	9545	OMIM:256040	Proteasome-associated autoinflammatory syndrome 1 and digenic forms		20
HP:0010051	HP:0001822	Hallux valgus	1	PTEN CL E G H	5728	9588	ORPHA:744	Proteus syndrome	HP:0040283 - Occasional	948
HP:0010051	HP:0001822	Hallux valgus	1	RBBP8 CL E G H	5932	9891	OMIM:251255	Jawad syndrome	.	68
HP:0010051	HP:0001822	Hallux valgus	1	RFC2 CL E G H	5982	9970	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	SCARF2 CL E G H	91179	19869	OMIM:600920	Van den Ende-Gupta syndrome	.	11
HP:0010051	HP:0001822	Hallux valgus	1	SF3B4 CL E G H	10262	10771	OMIM:154400	Acrofacial dysostosis 1, Nager type	.	49
HP:0010051	HP:0001822	Hallux valgus	1	SLC16A2 CL E G H	6567	10923	OMIM:300523	Allan-Herndon-Dudley syndrome	.	57
HP:0010051	HP:0001822	Hallux valgus	1	SLC29A3 CL E G H	55315	23096	ORPHA:168569	H syndrome	HP:0040283 - Occasional	68
HP:0010051	HP:0001822	Hallux valgus	1	SLC29A3 CL E G H	55315	23096	OMIM:602782	Histiocytosis-lymphadenopathy plus syndrome		68
HP:0010051	HP:0001822	Hallux valgus	1	SMARCA2 CL E G H	6595	11098	OMIM:601358	Nicolaides-Baraitser syndrome		146
HP:0010051	HP:0001822	Hallux valgus	1	SOX9 CL E G H	6662	11204	OMIM:114290	Campomelic dysplasia		109
HP:0010051	HP:0001822	Hallux valgus	1	SRY CL E G H	6736	11311	ORPHA:1772	45,X/46,XY mixed gonadal dysgenesis	HP:0040283 - Occasional	23
HP:0010051	HP:0001822	Hallux valgus	1	STX1A CL E G H	6804	11433	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	TBC1D2B CL E G H	23102	29183	ORPHA:397973	Intellectual disability-obesity-prognathism-eye and skin anomalies syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	TBL2 CL E G H	26608	11586	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	TCF12 CL E G H	6938	11623	OMIM:615314	Craniosynostosis 3	HP:0040283 - Occasional	28
HP:0010051	HP:0001822	Hallux valgus	1	TMEM270 CL E G H	135886	23018	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	TP63 CL E G H	8626	15979	OMIM:603543	Limb-Mammary syndrome	.	140
HP:0010051	HP:0001822	Hallux valgus	1	TTI2 CL E G H	80185	26262	OMIM:615541	Mental retardation, autosomal recessive 39		11
HP:0010051	HP:0001822	Hallux valgus	1	TWIST1 CL E G H	7291	12428	OMIM:101400	Saethre-Chotzen syndrome	.	18
HP:0010051	HP:0001822	Hallux valgus	1	TWIST1 CL E G H	7291	12428	ORPHA:794	Saethre-Chotzen syndrome	HP:0040283 - Occasional	18
HP:0010051	HP:0001822	Hallux valgus	1	USP7 CL E G H	7874	12630	OMIM:616863	Chromosome 16p13.2 deletion syndrome		2
HP:0010051	HP:0001822	Hallux valgus	1	USP9X CL E G H	8239	12632	ORPHA:480880	X-linked female restricted facial dysmorphism-short stature-choanal atresia-intellectual disability	HP:0040283 - Occasional	27
HP:0010051	HP:0001822	Hallux valgus	1	VPS37D CL E G H	155382	18287	ORPHA:904	Williams syndrome	HP:0040282 - Frequent
HP:0010051	HP:0001822	Hallux valgus	1	YY1 CL E G H	7528	12856	ORPHA:506358	Gabriele-de Vries syndrome	HP:0040283 - Occasional	7
HP:0010051	HP:0001822	Hallux valgus	1	YY1 CL E G H	7528	12856	OMIM:617557	Gabriele-De vries syndrome		7
HP:0010051	HP:0001822	Hallux valgus	1	ZEB2 CL E G H	9839	14881	ORPHA:261552	Mowat-Wilson syndrome due to a ZEB2 point mutation	HP:0040283 - Occasional	362
HP:0010051	HP:0001822	Hallux valgus	1	ZEB2 CL E G H	9839	14881	ORPHA:261537	Mowat-Wilson syndrome due to monosomy 2q22	HP:0040283 - Occasional	362
HP:0010051	HP:0001822	Hallux valgus	1	ZMIZ1 CL E G H	57178	16493	OMIM:618659	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND DISTAL SKELETAL ANOMALIES; NEDDFSA
HP:0010051	HP:0001822	Hallux valgus	1	ZNF469 CL E G H	84627	23216	ORPHA:90354	Brittle cornea syndrome	HP:0040283 - Occasional	397