Human Phenotype Ontology 
Grandparent Node:
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Abnormality of movement (HP:0100022)help
Parent Node:
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Involuntary movements (HP:0004305)help
..Starting node
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Tics (HP:0100033)help
Term ID: 100033
Name: Tics
Synonym: Tic disorder; Tics
Definition: Repeated, individually recognizable, intermittent movements or movement fragments that are almost always briefly suppresable and are usually associated with awareness of an urge to perform the movement.
Comments:
Reference: HP:0100033
Genes and Diseases:
 
       Child Nodes:
........expandMotor tics (HP:0100034) help
........expandPhonic tics (HP:0100035) help

 Sister Nodes: 
..expandAthetosis (HP:0002305) help
..expandChorea (HP:0002072) help
..expandClonus (HP:0002169) help
..expandFasciculations (HP:0002380) help
..expandHemiballismus (HP:0100248) help
..expandIntermittent painful muscle spasms (HP:0011964) help
..expandMyoclonus (HP:0001336) help
..expandParoxysmal dyskinesia (HP:0007166) help
..expandSelf-mutilation of tongue and lips due to involuntary movements (HP:0008767) help
..expandStereotypy (HP:0000733) help
..expandTremor (HP:0001337) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0100033HP:0100033Tics0ARID2 CL E G H196528617808COFFIN-SIRIS SYNDROME 6617808C4540499OMIM118618037609539
HP:0100033HP:0100033Tics0ARID2 CL E G H196528617808COFFIN-SIRIS SYNDROME 6617808C4540499OMIM117918037609539
HP:0100033HP:0100033Tics0VPS13A CL E G H23230200150Choreoacanthocytosis200150C0393576OMIM113741908605978
HP:0100033HP:0100033Tics0VPS13A CL E G H23230200150Choreoacanthocytosis200150C0393576OMIM112461908605978
HP:0100033HP:0100033Tics0ZSWIM6 CL E G H57688617865NEURODEVELOPMENTAL DISORDER WITH MOVEMENT ABNORMALITIES, ABNORMAL GAIT, AND AUTISTIC FEATURES617865CN800196OMIM111629316615951
HP:0100033HP:0100033Tics0ZSWIM6 CL E G H57688617865NEURODEVELOPMENTAL DISORDER WITH MOVEMENT ABNORMALITIES, ABNORMAL GAIT, AND AUTISTIC FEATURES617865CN800196OMIM125829316615951
HP:0100033HP:0100035Phonic tics1ARID2 CL E G H196528617808COFFIN-SIRIS SYNDROME 6617808C4540499OMIM117918037609539
HP:0100033HP:0100034Motor tics1ARID2 CL E G H196528617808COFFIN-SIRIS SYNDROME 6617808C4540499OMIM118618037609539
HP:0100033HP:0100034Motor tics1ARID2 CL E G H196528617808COFFIN-SIRIS SYNDROME 6617808C4540499OMIM117918037609539
HP:0100033HP:0100035Phonic tics1ARID2 CL E G H196528617808COFFIN-SIRIS SYNDROME 6617808C4540499OMIM118618037609539
HP:0100033HP:0100035Phonic tics1VPS13A CL E G H23230200150Choreoacanthocytosis200150C0393576OMIM112461908605978
HP:0100033HP:0100034Motor tics1VPS13A CL E G H23230200150Choreoacanthocytosis200150C0393576OMIM113741908605978
HP:0100033HP:0100034Motor tics1VPS13A CL E G H23230200150Choreoacanthocytosis200150C0393576OMIM112461908605978
HP:0100033HP:0100035Phonic tics1VPS13A CL E G H23230200150Choreoacanthocytosis200150C0393576OMIM113741908605978
HP:0100033HP:0100034Motor tics1ZSWIM6 CL E G H57688617865NEURODEVELOPMENTAL DISORDER WITH MOVEMENT ABNORMALITIES, ABNORMAL GAIT, AND AUTISTIC FEATURES617865CN800196OMIM111629316615951
HP:0100033HP:0100035Phonic tics1ZSWIM6 CL E G H57688617865NEURODEVELOPMENTAL DISORDER WITH MOVEMENT ABNORMALITIES, ABNORMAL GAIT, AND AUTISTIC FEATURES617865CN800196OMIM125829316615951
HP:0100033HP:0100035Phonic tics1ZSWIM6 CL E G H57688617865NEURODEVELOPMENTAL DISORDER WITH MOVEMENT ABNORMALITIES, ABNORMAL GAIT, AND AUTISTIC FEATURES617865CN800196OMIM111629316615951
HP:0100033HP:0100034Motor tics1ZSWIM6 CL E G H57688617865NEURODEVELOPMENTAL DISORDER WITH MOVEMENT ABNORMALITIES, ABNORMAL GAIT, AND AUTISTIC FEATURES617865CN800196OMIM125829316615951
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0100033HP:0100033Tics0BCR CL E G H613261330ORPHA02171014151410
HP:0100033HP:0100033Tics0BCR CL E G H613261330ORPHA02141014151410
HP:0100033HP:0100033Tics0CRKL CL E G H1399261330ORPHA03982363602007
HP:0100033HP:0100033Tics0CRKL CL E G H1399261330ORPHA04062363602007
HP:0100033HP:0100033Tics0GATAD2B CL E G H57459615074Mental retardation, autosomal dominant 18615074C3554448OMIM015930778614998
HP:0100033HP:0100033Tics0GATAD2B CL E G H57459615074Mental retardation, autosomal dominant 18615074C3554448OMIM021230778614998
HP:0100033HP:0100033Tics0MAPK1 CL E G H5594261330ORPHA01206871176948
HP:0100033HP:0100033Tics0MAPK1 CL E G H5594261330ORPHA01176871176948
HP:0100033HP:0100033Tics0PUF60 CL E G H22827508488ORPHA015117042604819
HP:0100033HP:0100033Tics0PUF60 CL E G H22827508488ORPHA016317042604819
HP:0100033HP:0100035Phonic tics1BCR CL E G H613261330ORPHA02141014151410
HP:0100033HP:0100034Motor tics1BCR CL E G H613261330ORPHA02171014151410
HP:0100033HP:0100034Motor tics1BCR CL E G H613261330ORPHA02141014151410
HP:0100033HP:0100035Phonic tics1BCR CL E G H613261330ORPHA02171014151410
HP:0100033HP:0100034Motor tics1CRKL CL E G H1399261330ORPHA03982363602007
HP:0100033HP:0100035Phonic tics1CRKL CL E G H1399261330ORPHA04062363602007
HP:0100033HP:0100035Phonic tics1CRKL CL E G H1399261330ORPHA03982363602007
HP:0100033HP:0100034Motor tics1CRKL CL E G H1399261330ORPHA04062363602007
HP:0100033HP:0100034Motor tics1GATAD2B CL E G H57459615074Mental retardation, autosomal dominant 18615074C3554448OMIM015930778614998
HP:0100033HP:0100035Phonic tics1GATAD2B CL E G H57459615074Mental retardation, autosomal dominant 18615074C3554448OMIM021230778614998
HP:0100033HP:0100035Phonic tics1GATAD2B CL E G H57459615074Mental retardation, autosomal dominant 18615074C3554448OMIM015930778614998
HP:0100033HP:0100034Motor tics1GATAD2B CL E G H57459615074Mental retardation, autosomal dominant 18615074C3554448OMIM021230778614998
HP:0100033HP:0100035Phonic tics1MAPK1 CL E G H5594261330ORPHA01176871176948
HP:0100033HP:0100034Motor tics1MAPK1 CL E G H5594261330ORPHA01206871176948
HP:0100033HP:0100034Motor tics1MAPK1 CL E G H5594261330ORPHA01176871176948
HP:0100033HP:0100035Phonic tics1MAPK1 CL E G H5594261330ORPHA01206871176948
HP:0100033HP:0100034Motor tics1PUF60 CL E G H22827508488ORPHA015117042604819
HP:0100033HP:0100035Phonic tics1PUF60 CL E G H22827508488ORPHA016317042604819
HP:0100033HP:0100035Phonic tics1PUF60 CL E G H22827508488ORPHA015117042604819
HP:0100033HP:0100034Motor tics1PUF60 CL E G H22827508488ORPHA016317042604819


Genes (11) :ARID2 BCR CRKL GATAD2B MAPK1 PANK2 PDGFB PUF60 SLITRK1 VPS13A ZSWIM6

Diseases (9) :617808 261330 615074 508488 200150 617865 234200 615483 137580
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.