MSeqDR Central Portal

About
MSeqDR-LSDB
Tools
- Quick-Mitome for WES
- Quick-Mitome
- Quick-Mitome Report
- mtDNA Tool:
- mvTool
- Phy-Mer
- MToolBox
- mvTool for Haplogroup
- mvTool with HmtDB
- MitoMaster
- MitoTIP tRNA Scoring
- MSeq-OpenCGA
- Variant Tool:
- VariantOneStop
- HBCR Exome (Retired)
- POLG Patho. Server
- Data - Awsomics GeEx
- Expert Panel
- Panel Tool:
- Gene Panel Examiner
- Transgenomic_NuclearMitome
- Pedigree Maker
- json2table
Phenome-Disease
Collaboration
- Genesis (GEM.App)
- LeighMap
- Expert Panel
- Collaboration Zone
Submission
- Submit_Interpret_Variant
- Instructions

Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

MSeqDR Central Portal

MSeqDR Data Summary for the Term ENSG00000187554:

Ensembl Gene ID	Associated Gene Name	LSDB Genes	LSDB Variants	clinVar hits	Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID	Description	Chr	Gene Start	Gene End	Strand	Band	Transcript Start bp	Transcript End bp	Associated Gene Name	Associated Transcript Name	Associated Gene DB	Associated Transcript DB	Transcript count	pct GC content	Gene Biotype	Transcript Biotype	Source Gene	Source Transcript	Status gene	Status transcript	EntrezGene ID	HGNC ID	HGNC Symbol	RefSeq mRNA	Seq region id
ENSG00000187554	TLR5	0	0	2	ENSG00000187554	ENST00000366881	ENSP00000355846	toll-like receptor 5 [Source:HGNC Symbol;Acc:11851]	1	223282748	223316624	-1	q41	223283647	223316624	TLR5	TLR5-001	HGNC Symbol	HGNC transcript name	6	46.61	protein_coding	protein_coding	ensembl_hava	havana	KNOWN	KNOWN	7100	11851	TLR5	NM_003268	27511

MSeqDR Master Exome Data Set M1: 122 entries from same gene

No.	Chr	Position	Reference	Variant	EnsemblTranscriptID	EnsemblGeneID	Gene_Start	Gene_End	EnsemblProteinID	Gene	strand	Uniprot	cChange	pChange	Nature	dbSNP	Freq	EVS	phastCons	SIFT	Polyphen	HGMD	type	samples
1	1	223283653	C	T	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	rs5744179	0.0057	-	-	-	-	-	het	1
2	1	223283653	C	T	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	rs5744179	0.0057	-	-	-	-	-	het	1
3	1	223283694	G	+A	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
4	1	223283694	G	+A	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
5	1	223283761	T	C	ENST00000342210	ENSG00000187554	223282748	223316624	ENSP00000340089	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	rs5744178	0.0057	C=0/T=8600;C=48/T=4358;C=48/T=12958	-	-	-	-	het	1
6	1	223283761	T	C	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	rs5744178	0.0057	C=0/T=8600;C=48/T=4358;C=48/T=12958	-	-	-	-	het	1
7	1	223283761	T	C	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	-	-	3'_UTR	rs5744178	0.0057	C=0/T=8600;C=48/T=4358;C=48/T=12958	-	-	-	-	het	1
8	1	223283837	T	C	ENST00000342210	ENSG00000187554	223282748	223316624	ENSP00000340089	TLR5	-1	TLR5_HUMAN	c.2537A>G	p.D846G	non-syn	rs5744177	0.00543	C=87/T=8513;C=36/T=4370;C=123/T=12883	-	TOLERATED	P	-	het	22
9	1	223283837	T	C	ENST00000342210	ENSG00000187554	223282748	223316624	ENSP00000340089	TLR5	-1	TLR5_HUMAN	c.2537A>G	p.D846G	non-syn	rs5744177	0.00543	C=87/T=8513;C=36/T=4370;C=123/T=12883	-	TOLERATED	P	-	hom	1
10	1	223283837	T	C	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	c.2537A>G	p.D846G	non-syn	rs5744177	0.00543	C=87/T=8513;C=36/T=4370;C=123/T=12883	-	TOLERATED	P	-	het	22
11	1	223283837	T	C	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	c.2537A>G	p.D846G	non-syn	rs5744177	0.00543	C=87/T=8513;C=36/T=4370;C=123/T=12883	-	TOLERATED	P	-	hom	1
12	1	223283837	T	C	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	c.2537A>G	p.D846G	non-syn	rs5744177	0.00543	C=87/T=8513;C=36/T=4370;C=123/T=12883	-	TOLERATED	P	-	het	22
13	1	223283837	T	C	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	c.2537A>G	p.D846G	non-syn	rs5744177	0.00543	C=87/T=8513;C=36/T=4370;C=123/T=12883	-	TOLERATED	P	-	hom	1
14	1	223283851	T	C	ENST00000342210	ENSG00000187554	223282748	223316624	ENSP00000340089	TLR5	-1	TLR5_HUMAN	c.2523A>G	p.K841K	syn	rs1053954	0.08743	C=880/T=7720;C=67/T=4339;C=947/T=12059	-	-	-	-	het	120
15	1	223283851	T	C	ENST00000342210	ENSG00000187554	223282748	223316624	ENSP00000340089	TLR5	-1	TLR5_HUMAN	c.2523A>G	p.K841K	syn	rs1053954	0.08743	C=880/T=7720;C=67/T=4339;C=947/T=12059	-	-	-	-	hom	11
16	1	223283851	T	C	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	c.2523A>G	p.K841K	syn	rs1053954	0.08743	C=880/T=7720;C=67/T=4339;C=947/T=12059	-	-	-	-	het	120
17	1	223283851	T	C	ENST00000366881	ENSG00000187554	223282748	223316624	ENSP00000355846	TLR5	-1	TLR5_HUMAN	c.2523A>G	p.K841K	syn	rs1053954	0.08743	C=880/T=7720;C=67/T=4339;C=947/T=12059	-	-	-	-	hom	11
18	1	223283851	T	C	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	c.2523A>G	p.K841K	syn	rs1053954	0.08743	C=880/T=7720;C=67/T=4339;C=947/T=12059	-	-	-	-	het	120
19	1	223283851	T	C	ENST00000540964	ENSG00000187554	223282748	223316624	ENSP00000440643	TLR5	-1	TLR5_HUMAN	c.2523A>G	p.K841K	syn	rs1053954	0.08743	C=880/T=7720;C=67/T=4339;C=947/T=12059	-	-	-	-	hom	11
20	1	223283881	T	C	ENST00000342210	ENSG00000187554	223282748	223316624	ENSP00000340089	TLR5	-1	TLR5_HUMAN	c.2493A>G	p.K831K	syn	rs75283814	0.00457	C=86/T=8514;C=12/T=4394;C=98/T=12908	lod=27:321	-	-	-	het	18

** A friendly reminder: guest user can access up to first 20 entries per gene from MSeqDR Master Exome Data Set M1. To gain access to the full power of MSeqDR, please login, or register, then request access to data.

As MSeqDR registered user , your accessible protected data set after login:

Select a dataset from the above drop-down list,
**click here to view variant details for this gene in selected data set**,
and click "Export" button to save as csv.

Transcripts and variants in the surrounding TLR5 1:223282748..223316624 region Gbrowse