Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Behavioral abnormality (HP:0000708)

Parent Node:
Abnormal emotion/affect behavior (HP:0100851)

..Starting node
..Mood swings (HP:0000720)

Term ID:

720

Name:

Mood swings

Synonym:

Mood swings

Definition:

An exaggeration of emotional affects such as laughing crying, or yawning beyond what the person feels.

Comments:

Reference:

HP:0000720

Genes and Diseases:

Child Nodes:

Sister Nodes:

Abnormal aggressive, impulsive or violent behavior (HP:0006919)

Conspicuously happy disposition (HP:0100024)

Diminished motivation (HP:0000745)

Emotional blunting (HP:0030213)

Euphoria (HP:0031844)

Happy demeanor (HP:0040082)

Irritability (HP:0000737)

obsolete Mood changes (HP:0001575)

Suicidal ideation (HP:0031589)

Unhappy demeanor (HP:0031588)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	DiseaseId	DiseaseName	DiseaseMIM	ConceptID	Source	Typical association	ClinVar variants	HGNC ID	GeneMIM
HPO disease - gene - phenotype typical associations:
HP:0000720	HP:0000720	Mood swings	0	CUL4B CL E G H	8450	300354	Syndromic X-linked mental retardation, Cabezas type	300354	C1845861	OMIM	1	415	2555	300304
HP:0000720	HP:0000720	Mood swings	0	DEAF1 CL E G H	10522	617171	Dyskinesia, seizures, and intellectual developmental disorder	617171	C4310683	OMIM	1	695	14677	602635
HP:0000720	HP:0000720	Mood swings	0	DEAF1 CL E G H	10522	615828	Mental retardation, autosomal dominant 24	615828	C4014414	OMIM	1	695	14677	602635
HP:0000720	HP:0000720	Mood swings	0	DGCR2 CL E G H	9993	192430	Shprintzen syndrome	192430	C0220704	OMIM	1	458	2845	600594
HP:0000720	HP:0000720	Mood swings	0	DGCR6 CL E G H	8214	192430	Shprintzen syndrome	192430	C0220704	OMIM	1	361	2846	601279
HP:0000720	HP:0000720	Mood swings	0	DGCR8 CL E G H	54487	192430	Shprintzen syndrome	192430	C0220704	OMIM	1	442	2847	609030
HP:0000720	HP:0000720	Mood swings	0	ESS2 CL E G H	8220	192430	Shprintzen syndrome	192430	C0220704	OMIM	1	443	16817	601755
HP:0000720	HP:0000720	Mood swings	0	TBX1 CL E G H	6899	192430	Shprintzen syndrome	192430	C0220704	OMIM	1	1169	11592	602054
HP:0000720	HP:0000720	Mood swings	0	ZFYVE26 CL E G H	23503	270700	Spastic paraplegia 15	270700	C1849128	OMIM	1	2408	20761	612012
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000720	HP:0000720	Mood swings	0	BPTF CL E G H	2186	529962				ORPHA	0	573	3581	601819
HP:0000720	HP:0000720	Mood swings	0	PSMD12 CL E G H	5718	529962				ORPHA	0	84	9557	604450

Genes (10) :BPTF CUL4B DEAF1 DGCR2 DGCR6 DGCR8 ESS2 PSMD12 TBX1 ZFYVE26

Diseases (6) :529962 300354 617171 615828 192430 270700

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.

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