Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of higher mental function (HP:0011446)

Parent Node:
Neurological speech impairment (HP:0002167)

..Starting node
..Incomprehensible speech (HP:0002546)

Term ID:

2546

Name:

Incomprehensible speech

Synonym:

Incomprehensible speech

Definition:

Comments:

Reference:

HP:0002546

Genes and Diseases:

Child Nodes:

Sister Nodes:

Absent speech (HP:0001344)

Alexia (HP:0010523)

Anarthria (HP:0002425)

Anomic aphasia (HP:0030784)

Aphasia (HP:0002381)

Deficit in nonword repetition (HP:0002526)

Dysarthria (HP:0001260)

Dysgraphia (HP:0010526)

Dysphasia (HP:0002357)

Dysphonia (HP:0001618)

Echolalia (HP:0010529)

Grammar-specific speech disorder (HP:0006977)

Loss of speech (HP:0002371)

Mutism (HP:0002300)

Palilalia (HP:0031814)

Poor speech (HP:0002465)

Scanning speech (HP:0002168)

Stuttering (HP:0025268)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	DiseaseId	DiseaseName	DiseaseMIM	ConceptID	Source	Typical association	ClinVar variants	HGNC ID	GeneMIM
HPO disease - gene - phenotype typical associations:
HP:0002546	HP:0002546	Incomprehensible speech	0	CC2D1A CL E G H	54862	608443	Mental retardation, autosomal recessive 3	608443	C1838023	OMIM	1	263	30237	610055
HP:0002546	HP:0002546	Incomprehensible speech	0	FOXP2 CL E G H	93986	602081	Speech-language disorder 1	602081	C0750927	OMIM	1	376	13875	605317
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002546	HP:0002546	Incomprehensible speech	0	FXN CL E G H	2395	95				ORPHA	0	158	3951	606829
HP:0002546	HP:0002546	Incomprehensible speech	0	SATB2 CL E G H	23314	251019				ORPHA	0	684	21637	608148

Genes (4) :CC2D1A FOXP2 FXN SATB2

Diseases (4) :608443 602081 95 251019

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.