Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Human Phenotype Ontology

Grandparent Node:
All (HP:0000001)

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Parent Node:
Phenotypic abnormality (HP:0000118)

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..Starting node
..Abnormality of blood and blood-forming tissues (HP:0001871)

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Term ID:	1871
Name:	Abnormality of blood and blood-forming tissues
Synonym:	Abnormality of blood and blood-forming tissues; Abnormality of the haematopoietic system; Abnormality of the hematopoietic system; Haematological abnormality; Hematologic disease; Hematological abnormality
Definition:	An abnormality of the hematopoietic system.
Comments:
Reference:	HP:0001871
Genes and Diseases:	There are 825 terms for your input, too many to show detail here. Please try its child terms.
Child Nodes:
........Abnormal thrombocyte morphology (HP:0001872) ................... HP:0011869 Abnormal platelet function ................... HP:0011873 Abnormal platelet count ................... HP:0011875 Abnormal platelet morphology ................... HP:0011876 Abnormal platelet volume
........Abnormal erythrocyte morphology (HP:0001877) ................... HP:0001901 Polycythemia ................... HP:0001903 Anemia ................... HP:0004312 Abnormality of reticulocytes ................... HP:0004447 Poikilocytosis ................... HP:0004825 Increased hemoglobin oxygen affinity ................... HP:0005502 Increased red cell osmotic fragility ................... HP:0005546 Increased red cell osmotic resistance ................... HP:0010970 Blood group antigen abnormality ................... HP:0011273 Anisocytosis ................... HP:0011902 Abnormal hemoglobin ................... HP:0012131 Abnormal number of erythroid precursors ................... HP:0012134 Dysplastic erythropoesis ................... HP:0025065 Abnormal erythrocyte volume ................... HP:0030271 Reduced erythrocyte 2,3-diphosphoglycerate concentration ................... HP:0030272 Abnormal erythrocyte enzyme activity ................... HP:0031850 Abnormal hematocrit ................... HP:0031898 Rouleaux formation
........Abnormal leukocyte morphology (HP:0001881) ................... HP:0001909 Leukemia ................... HP:0004332 Abnormal lymphocyte morphology ................... HP:0010974 Abnormality of myeloid leukocytes ................... HP:0011893 Abnormal leukocyte count ................... HP:0012144 Abnormality monocyte morphology
........Abnormal bleeding (HP:0001892) ................... HP:0000132 Menorrhagia ................... HP:0000225 Gingival bleeding ................... HP:0000421 Epistaxis ................... HP:0001933 Subcutaneous hemorrhage ................... HP:0001934 Persistent bleeding after trauma ................... HP:0003010 Prolonged bleeding time ................... HP:0011029 Internal hemorrhage ................... HP:0011884 Abnormal umbilical stump bleeding ................... HP:0011888 Bleeding requiring red cell transfusion ................... HP:0011889 Bleeding with minor or no trauma ................... HP:0011890 Prolonged bleeding following procedure ................... HP:0012541 Cephalohematoma ................... HP:0030138 Excessive bleeding from superficial cuts ................... HP:0030139 Excessive bleeding after a venipuncture ................... HP:0030140 Oral cavity bleeding ................... HP:0040231 Abnormal onset of bleeding
........Abnormality of coagulation (HP:0001928) ................... HP:0003256 Abnormality of the coagulation cascade ................... HP:0003645 Prolonged partial thromboplastin time ................... HP:0005542 Prolonged whole-blood clotting time ................... HP:0040224 Abnormality of fibrinolysis ................... HP:0100724 Hypercoagulability
........Abnormal thrombosis (HP:0001977) ................... HP:0001907 Thromboembolism ................... HP:0002641 Peripheral thrombosis ................... HP:0004420 Arterial thrombosis ................... HP:0004936 Venous thrombosis ................... HP:0005521 Disseminated intravascular coagulation
........Extramedullary hematopoiesis (HP:0001978)
........Hematological neoplasm (HP:0004377) ................... HP:0001909 Leukemia ................... HP:0002665 Lymphoma ................... HP:0002863 Myelodysplasia ................... HP:0005523 Lymphoproliferative disorder ................... HP:0006775 Multiple myeloma ................... HP:0006782 Malignant eosinophil proliferation ................... HP:0011857 Plasmacytoma
........Abnormality of bone marrow cell morphology (HP:0005561) ................... HP:0012129 Abnormality of bone marrow stromal cells ................... HP:0012135 Abnormal granulocytopoietic cell morphology ................... HP:0012143 Abnormal megakaryocyte morphology ................... HP:0012145 Abnormality of multiple cell lineages in the bone marrow ................... HP:0020048 Reduced bone-marrow pro-B cell count
........Abnormal myeloid cell morphology (HP:0020047) ................... HP:0012130 Abnormal erythroid lineage cell morphology
Sister Nodes:
..Abnormal cellular phenotype (HP:0025354)
..Abnormality of connective tissue (HP:0003549)
..Abnormality of head or neck (HP:0000152)
..Abnormality of limbs (HP:0040064)
..Abnormality of metabolism/homeostasis (HP:0001939)
..Abnormality of prenatal development or birth (HP:0001197)
..Abnormality of the breast (HP:0000769)
..Abnormality of the cardiovascular system (HP:0001626)
..Abnormality of the digestive system (HP:0025031)
..Abnormality of the ear (HP:0000598)
..Abnormality of the endocrine system (HP:0000818)
..Abnormality of the eye (HP:0000478)
..Abnormality of the genitourinary system (HP:0000119)
..Abnormality of the immune system (HP:0002715)
..Abnormality of the integument (HP:0001574)
..Abnormality of the musculature (HP:0003011)
..Abnormality of the nervous system (HP:0000707)
..Abnormality of the respiratory system (HP:0002086)
..Abnormality of the skeletal system (HP:0000924)
..Abnormality of the thoracic cavity (HP:0045027)
..Abnormality of the voice (HP:0001608)
..Constitutional symptom (HP:0025142)
..Growth abnormality (HP:0001507)
..Neoplasm (HP:0002664)
..obsolete Abnormal test result (HP:0500014)
Genes (0) : Diseases (0) :
Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.

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