Human Phenotype Ontology 
Grandparent Node:
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Neoplasm (HP:0002664)help
Parent Node:
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Neoplasm by anatomical site (HP:0011793)help
..Starting node
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Malignant mesothelioma (HP:0100001)help
Term ID: 100001
Name: Malignant mesothelioma
Synonym:
Definition: Malignant mesothelioma is a form of cancer that originates from the cells of the mesothelium, a thin tissue layer surrounding the body's internal organs. Malignant mesothelioma is almost exclusively caused by asbestos exposure, pleural mesothelioma beeing the most common form, affecting the lining of the lungs called the pleura. Other forms such as perioneal-, percardial- or testicular- mesothelioma are much rarer.
Comments:
Reference: HP:0100001
Genes and Diseases:
 
       Child Nodes:
........expandPleural mesothelioma (HP:0100002) help
........expandPeritoneal mesothelioma (HP:0100003) help
........expandPericardial mesothelioma (HP:0100004) help
........expandTesticular mesothelioma (HP:0100005) help

 Sister Nodes: 
..expandHematological neoplasm (HP:0004377) help
..expandNeoplasm of fatty tissue (HP:0200013) help
..expandNeoplasm of head and neck (HP:0012288) help
..expandNeoplasm of striated muscle (HP:0009728) help
..expandNeoplasm of the breast (HP:0100013) help
..expandNeoplasm of the ear (HP:0012780) help
..expandNeoplasm of the endocrine system (HP:0100568) help
..expandNeoplasm of the eye (HP:0100012) help
..expandNeoplasm of the gastrointestinal tract (HP:0007378) help
..expandNeoplasm of the genitourinary tract (HP:0007379) help
..expandNeoplasm of the heart (HP:0100544) help
..expandNeoplasm of the lip (HP:0100604) help
..expandNeoplasm of the nail (HP:0100826) help
..expandNeoplasm of the nervous system (HP:0004375) help
..expandNeoplasm of the oral cavity (HP:0100649) help
..expandNeoplasm of the pancreas (HP:0002894) help
..expandNeoplasm of the respiratory system (HP:0100606) help
..expandNeoplasm of the skeletal system (HP:0010622) help
..expandNeoplasm of the skin (HP:0008069) help
..expandNeoplasm of the thymus (HP:0100521) help
..expandRetroperitoneal chemodectomas (HP:0006729) help
..expandSoft tissue neoplasm (HP:0031459) help
..expandVascular neoplasm (HP:0100742) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0100001HP:0100001Malignant mesothelioma0BAP1 CL E G H8314950OMIM:614327Tumor predisposition syndrome184
HP:0100001HP:0100001Malignant mesothelioma0BCL10 CL E G H8915989OMIM:156240Mesothelioma, malignant.18
HP:0100001HP:0100001Malignant mesothelioma0WT1 CL E G H749012796OMIM:156240Mesothelioma, malignant.177
HP:0100001HP:0100005Testicular mesothelioma1 CL E G H
HP:0100001HP:0100004Pericardial mesothelioma1 CL E G H
HP:0100001HP:0100003Peritoneal mesothelioma1 CL E G H
HP:0100001HP:0100002Pleural mesothelioma1 CL E G H


Genes (3) :BAP1 BCL10 WT1

Diseases (2) :OMIM:614327 OMIM:156240
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.