Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abdominal symptom (HP:0011458)

Parent Node:
Feeding difficulties (HP:0011968)

..Starting node
..Nasogastric tube feeding (HP:0040288)

Term ID:

40288

Name:

Nasogastric tube feeding

Synonym:

Definition:

The condition of inability to eat normally treated by placement of a thin tube through the nose into the stomach that is then used to carry food.

Comments:

Reference:

HP:0040288

Genes and Diseases:

Child Nodes:

Sister Nodes:

Delayed self-feeding during toddler years (HP:0012381)

Feeding difficulties in infancy (HP:0008872)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0040288	HP:0040288	Nasogastric tube feeding	0	AASS CL E G H	10157	17366	ORPHA:2203	Hyperlysinemia	HP:0040283 - Occasional	15
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ABCD1 CL E G H	215	61	ORPHA:139396	X-linked cerebral adrenoleukodystrophy	HP:0040283 - Occasional	135
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ACSF3 CL E G H	197322	27288	ORPHA:289504	Combined malonic and methylmalonic acidemia	HP:0040283 - Occasional	68
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ALG2 CL E G H	85365	23159	OMIM:607906	Congenital disorder of glycosylation, type Ii		46
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ANAPC1 CL E G H	64682	19988	ORPHA:221008	Rothmund-Thomson syndrome type 1	HP:0040283 - Occasional	2
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ASPA CL E G H	443	756	ORPHA:314911	Severe Canavan disease	HP:0040283 - Occasional	48
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ASXL3 CL E G H	80816	29357	OMIM:615485	BAINBRIDGE-ROPERS SYNDROME; BRPS		49
HP:0040288	HP:0040288	Nasogastric tube feeding	0	BSND CL E G H	7809	16512	ORPHA:89938	Infantile Bartter syndrome with sensorineural deafness	HP:0040283 - Occasional	53
HP:0040288	HP:0040288	Nasogastric tube feeding	0	CARS2 CL E G H	79587	25695	ORPHA:477774	Combined oxidative phosphorylation defect type 27	HP:0040283 - Occasional	35
HP:0040288	HP:0040288	Nasogastric tube feeding	0	CLCNKA CL E G H	1187	2026	ORPHA:89938	Infantile Bartter syndrome with sensorineural deafness	HP:0040283 - Occasional	9
HP:0040288	HP:0040288	Nasogastric tube feeding	0	CLCNKB CL E G H	1188	2027	ORPHA:89938	Infantile Bartter syndrome with sensorineural deafness	HP:0040283 - Occasional	27
HP:0040288	HP:0040288	Nasogastric tube feeding	0	COL4A5 CL E G H	1287	2207	ORPHA:1018	X-linked Alport syndrome-diffuse leiomyomatosis	HP:0040283 - Occasional	678
HP:0040288	HP:0040288	Nasogastric tube feeding	0	COL4A6 CL E G H	1288	2208	ORPHA:1018	X-linked Alport syndrome-diffuse leiomyomatosis	HP:0040283 - Occasional	18
HP:0040288	HP:0040288	Nasogastric tube feeding	0	DPM2 CL E G H	8818	3006	ORPHA:329178	Congenital muscular dystrophy with intellectual disability and severe epilepsy	HP:0040283 - Occasional	26
HP:0040288	HP:0040288	Nasogastric tube feeding	0	EPM2A CL E G H	7957	3413	ORPHA:501	Lafora disease	HP:0040282 - Frequent	83
HP:0040288	HP:0040288	Nasogastric tube feeding	0	FOXP3 CL E G H	50943	6106	ORPHA:37042	Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome	HP:0040284 - Very rare	32
HP:0040288	HP:0040288	Nasogastric tube feeding	0	GNB2 CL E G H	2783	4398	OMIM:619503	NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND DYSMORPHIC FACIES; NEDHYDF
HP:0040288	HP:0040288	Nasogastric tube feeding	0	GRIN1 CL E G H	2902	4584	ORPHA:208447	Bilateral generalized polymicrogyria	HP:0040283 - Occasional	108
HP:0040288	HP:0040288	Nasogastric tube feeding	0	HECW2 CL E G H	57520	29853	OMIM:617268	Neurodevelopmental disorder with hypotonia, seizures, and absent language		11
HP:0040288	HP:0040288	Nasogastric tube feeding	0	KCNK9 CL E G H	51305	6283	ORPHA:166108	Intellectual disability, Birk-Barel type	HP:0040282 - Frequent	4
HP:0040288	HP:0040288	Nasogastric tube feeding	0	KNSTRN CL E G H	90417	30767	ORPHA:221139	Combined immunodeficiency with faciooculoskeletal anomalies	HP:0040282 - Frequent	1
HP:0040288	HP:0040288	Nasogastric tube feeding	0	MAGEL2 CL E G H	54551	6814	ORPHA:398069	MAGEL2-related Prader-Willi-like syndrome	HP:0040282 - Frequent	63
HP:0040288	HP:0040288	Nasogastric tube feeding	0	MFF CL E G H	56947	24858	ORPHA:485421	MFF-related encephalopathy due to mitochondrial and peroxisomal fission defect	HP:0040282 - Frequent	17
HP:0040288	HP:0040288	Nasogastric tube feeding	0	MOGS CL E G H	7841	24862	ORPHA:79330	MOGS-CDG	HP:0040283 - Occasional	37
HP:0040288	HP:0040288	Nasogastric tube feeding	0	MPDU1 CL E G H	9526	7207	ORPHA:79323	MPDU1-CDG		32
HP:0040288	HP:0040288	Nasogastric tube feeding	0	MYL1 CL E G H	4632	7582	OMIM:618414	Myopathy, congenital, with fast-twitch (type ii) fiber atrophy
HP:0040288	HP:0040288	Nasogastric tube feeding	0	NACC1 CL E G H	112939	20967	ORPHA:500545	Severe neurodevelopmental disorder with feeding difficulties-stereotypic hand movement-bilateral cataract	HP:0040283 - Occasional	1
HP:0040288	HP:0040288	Nasogastric tube feeding	0	NHLRC1 CL E G H	378884	21576	ORPHA:501	Lafora disease	HP:0040282 - Frequent	77
HP:0040288	HP:0040288	Nasogastric tube feeding	0	NONO CL E G H	4841	7871	ORPHA:466791	Macrocephaly-intellectual disability-left ventricular non compaction syndrome	HP:0040283 - Occasional	10
HP:0040288	HP:0040288	Nasogastric tube feeding	0	PACS1 CL E G H	55690	30032	ORPHA:329224	Intellectual disability-craniofacial dysmorphism-cryptorchidism syndrome	HP:0040283 - Occasional	24
HP:0040288	HP:0040288	Nasogastric tube feeding	0	PIK3CD CL E G H	5293	8977	ORPHA:221139	Combined immunodeficiency with faciooculoskeletal anomalies	HP:0040282 - Frequent	9
HP:0040288	HP:0040288	Nasogastric tube feeding	0	PLP1 CL E G H	5354	9086	ORPHA:280210	Pelizaeus-Merzbacher disease, connatal form	HP:0040283 - Occasional	60
HP:0040288	HP:0040288	Nasogastric tube feeding	0	PSAT1 CL E G H	29968	19129	ORPHA:284417	Phosphoserine aminotransferase deficiency, infantile/juvenile form	HP:0040283 - Occasional	27
HP:0040288	HP:0040288	Nasogastric tube feeding	0	PTCD3 CL E G H	55037	24717	OMIM:619057	COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 51; COXPD51
HP:0040288	HP:0040288	Nasogastric tube feeding	0	RECQL4 CL E G H	9401	9949	ORPHA:221016	Rothmund-Thomson syndrome type 2	HP:0040283 - Occasional	445
HP:0040288	HP:0040288	Nasogastric tube feeding	0	SIM1 CL E G H	6492	10882	ORPHA:398079	SIM1-related Prader-Willi-like syndrome	HP:0040282 - Frequent	40
HP:0040288	HP:0040288	Nasogastric tube feeding	0	SLC35A2 CL E G H	7355	11022	ORPHA:356961	SLC35A2-CDG	HP:0040282 - Frequent	27
HP:0040288	HP:0040288	Nasogastric tube feeding	0	SRCAP CL E G H	10847	16974	ORPHA:2044	Floating-Harbor syndrome	HP:0040283 - Occasional	138
HP:0040288	HP:0040288	Nasogastric tube feeding	0	VPS50 CL E G H	55610	25956	OMIM:619685	NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, SEIZURES, AND NEONATAL CHOLESTASIS; NEDMSC
HP:0040288	HP:0040288	Nasogastric tube feeding	0	WAC CL E G H	51322	17327	ORPHA:466950	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation	HP:0040283 - Occasional	20
HP:0040288	HP:0040288	Nasogastric tube feeding	0	ZNF699 CL E G H	374879	24750	OMIM:619488	DEGCAGS SYNDROME; DEGCAGS

Genes (41) :AASS ABCD1 ACSF3 ALG2 ANAPC1 ASPA ASXL3 BSND CARS2 CLCNKA CLCNKB COL4A5 COL4A6 DPM2 EPM2A FOXP3 GNB2 GRIN1 HECW2 KCNK9 KNSTRN MAGEL2 MFF MOGS MPDU1 MYL1 NACC1 NHLRC1 NONO PACS1 PIK3CD PLP1 PSAT1 PTCD3 RECQL4 SIM1 SLC35A2 SRCAP VPS50 WAC ZNF699

Diseases (36) :ORPHA:2203 ORPHA:139396 ORPHA:289504 OMIM:607906 ORPHA:221008 ORPHA:314911 OMIM:615485 ORPHA:89938 ORPHA:477774 ORPHA:1018 ORPHA:329178 ORPHA:501 ORPHA:37042 OMIM:619503 ORPHA:208447 OMIM:617268 ORPHA:166108 ORPHA:221139 ORPHA:398069 ORPHA:485421 ORPHA:79330 ORPHA:79323 OMIM:618414 ORPHA:500545 ORPHA:466791 ORPHA:329224 ORPHA:280210 ORPHA:284417 OMIM:619057 ORPHA:221016 ORPHA:398079 ORPHA:356961 ORPHA:2044 OMIM:619685 ORPHA:466950 OMIM:619488

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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