Human Phenotype Ontology 
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Reduced forced expiratory volume in one second (HP:0032342)help
Term ID: 32342
Name: Reduced forced expiratory volume in one second
Synonym: Reduced FEV1
Definition: An abnormal reduction in the amount of air a person can forcefully expel in one second.
Comments:
Reference: HP:0032342
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0032342HP:0032342Reduced forced expiratory volume in one second0CEACAM3 CL E G H10841815ORPHA:586Cystic fibrosis
HP:0032342HP:0032342Reduced forced expiratory volume in one second0CEACAM6 CL E G H46801818ORPHA:586Cystic fibrosis1
HP:0032342HP:0032342Reduced forced expiratory volume in one second0CFTR CL E G H10801884OMIM:219700Cystic fibrosis1371
HP:0032342HP:0032342Reduced forced expiratory volume in one second0CFTR CL E G H10801884ORPHA:586Cystic fibrosis1371
HP:0032342HP:0032342Reduced forced expiratory volume in one second0CLCA4 CL E G H228022018ORPHA:586Cystic fibrosis
HP:0032342HP:0032342Reduced forced expiratory volume in one second0CSF2RA CL E G H14382435OMIM:300770SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 4; SMDP415
HP:0032342HP:0032342Reduced forced expiratory volume in one second0DCTN4 CL E G H5116415518ORPHA:586Cystic fibrosis
HP:0032342HP:0032342Reduced forced expiratory volume in one second0DNAH9 CL E G H17702953OMIM:618300Ciliary dyskinesia, primary, 4018
HP:0032342HP:0032342Reduced forced expiratory volume in one second0EDNRA CL E G H19093179ORPHA:586Cystic fibrosis3
HP:0032342HP:0032342Reduced forced expiratory volume in one second0FCGR2A CL E G H22123616OMIM:219700Cystic fibrosis6
HP:0032342HP:0032342Reduced forced expiratory volume in one second0GCLC CL E G H27294311ORPHA:586Cystic fibrosis2
HP:0032342HP:0032342Reduced forced expiratory volume in one second0GSTM3 CL E G H29474635ORPHA:586Cystic fibrosis1
HP:0032342HP:0032342Reduced forced expiratory volume in one second0HFE CL E G H30774886ORPHA:586Cystic fibrosis38
HP:0032342HP:0032342Reduced forced expiratory volume in one second0HMOX1 CL E G H31625013ORPHA:586Cystic fibrosis3
HP:0032342HP:0032342Reduced forced expiratory volume in one second0ITCH CL E G H8373713890OMIM:613385AUTOIMMUNE DISEASE, MULTISYSTEM, WITH FACIAL DYSMORPHISM; ADMFD3
HP:0032342HP:0032342Reduced forced expiratory volume in one second0KCNN4 CL E G H37836293ORPHA:586Cystic fibrosis3
HP:0032342HP:0032342Reduced forced expiratory volume in one second0MIF CL E G H42827097ORPHA:586Cystic fibrosis1
HP:0032342HP:0032342Reduced forced expiratory volume in one second0NEK10 CL E G H15211018592OMIM:618781CILIARY DYSKINESIA, PRIMARY, 44; CILD44
HP:0032342HP:0032342Reduced forced expiratory volume in one second0PARN CL E G H50738609OMIM:616371PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 4; PFBMFT426
HP:0032342HP:0032342Reduced forced expiratory volume in one second0RTEL1 CL E G H5175015888OMIM:616373PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 3; PFBMFT377
HP:0032342HP:0032342Reduced forced expiratory volume in one second0SERPINA1 CL E G H52658941ORPHA:586Cystic fibrosis131
HP:0032342HP:0032342Reduced forced expiratory volume in one second0SLC11A1 CL E G H655610907ORPHA:586Cystic fibrosis2
HP:0032342HP:0032342Reduced forced expiratory volume in one second0SLC26A9 CL E G H11501914469ORPHA:586Cystic fibrosis5
HP:0032342HP:0032342Reduced forced expiratory volume in one second0SLC6A14 CL E G H1125411047ORPHA:586Cystic fibrosis
HP:0032342HP:0032342Reduced forced expiratory volume in one second0SLC9A3 CL E G H655011073ORPHA:586Cystic fibrosis7
HP:0032342HP:0032342Reduced forced expiratory volume in one second0STK36 CL E G H2714817209OMIM:619436CILIARY DYSKINESIA, PRIMARY, 46; CILD463
HP:0032342HP:0032342Reduced forced expiratory volume in one second0STX1A CL E G H680411433ORPHA:586Cystic fibrosis
HP:0032342HP:0032342Reduced forced expiratory volume in one second0TGFB1 CL E G H704011766OMIM:219700Cystic fibrosis13
HP:0032342HP:0032342Reduced forced expiratory volume in one second0TGFB1 CL E G H704011766ORPHA:586Cystic fibrosis13
HP:0032342HP:0032358Decreased post-bronchodilator forced expiratory volume in one second1 CL E G H


Genes (27) :CEACAM3 CEACAM6 CFTR CLCA4 CSF2RA DCTN4 DNAH9 EDNRA FCGR2A GCLC GSTM3 HFE HMOX1 ITCH KCNN4 MIF NEK10 PARN RTEL1 SERPINA1 SLC11A1 SLC26A9 SLC6A14 SLC9A3 STK36 STX1A TGFB1

Diseases (9) :ORPHA:586 OMIM:219700 OMIM:300770 OMIM:618300 OMIM:613385 OMIM:618781 OMIM:616371 OMIM:616373 OMIM:619436
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.