Term ID: |
31919 |
Name: |
Juvenile type ovarian granulosa cell tumor |
Synonym: |
Juvenile type ovarian granulosa cell tumour; Ovarian juvenile granulosa cell tumor; Ovarian juvenile granulosa cell tumour |
Definition: |
Juvenile granulosa cell ovarian tumor (JGCOT) is a rare sex cord stromal tumor, occuring most frequently in premenarchal girls or young women. In contrast to adult granulosa cell tumor, JGCOT has a high mitotic index and more aggressive tumor growth. Microscopically it is seen as diffuse and regularly distributed neoplastic cells with a wide cytoplasm and pleomorphic hyperchromatic nucleus. Follicle formation, in various sizes and shapes, is important in JGCOT. Call-Exner bodies are infrequently seen in JGCOT in contrast to the adult type. |
Comments: |
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Reference: |
HP:0031919 |
Genes and Diseases: | |
Child Nodes: |
Sister Nodes: |
Genes (1) :MBD4
Diseases (1) :OMIM:619975 |
Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.
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