Human Phenotype Ontology 
..Starting node
..expand
Juvenile type ovarian granulosa cell tumor (HP:0031919)help
Term ID: 31919
Name: Juvenile type ovarian granulosa cell tumor
Synonym: Juvenile type ovarian granulosa cell tumour; Ovarian juvenile granulosa cell tumor; Ovarian juvenile granulosa cell tumour
Definition: Juvenile granulosa cell ovarian tumor (JGCOT) is a rare sex cord stromal tumor, occuring most frequently in premenarchal girls or young women. In contrast to adult granulosa cell tumor, JGCOT has a high mitotic index and more aggressive tumor growth. Microscopically it is seen as diffuse and regularly distributed neoplastic cells with a wide cytoplasm and pleomorphic hyperchromatic nucleus. Follicle formation, in various sizes and shapes, is important in JGCOT. Call-Exner bodies are infrequently seen in JGCOT in contrast to the adult type.
Comments:
Reference: HP:0031919
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031919HP:0031919Juvenile type ovarian granulosa cell tumor0MBD4 CL E G H89306919OMIM:6199751


Genes (1) :MBD4

Diseases (1) :OMIM:619975
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.