Human Phenotype Ontology 
Grandparent Node:
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Abnormal lung morphology (HP:0002088)help
Grandparent Node:
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Neoplasm of the respiratory system (HP:0100606)help
Parent Node:
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Neoplasm of the lung (HP:0100526)help
..Starting node
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Non-small cell lung carcinoma (HP:0030358)help
Term ID: 30358
Name: Non-small cell lung carcinoma
Synonym: Non-small cell lung cancer
Definition:
Comments:
Reference: HP:0030358
Genes and Diseases:
 
       Child Nodes:
........expandLung adenocarcinoma (HP:0030078) help
........expandSquamous cell lung carcinoma (HP:0030359) help
........expandLarge cell lung carcinoma (HP:0030360) help

 Sister Nodes: 
..expandBronchial neoplasm (HP:0030077) help
..expandLung fibroma (HP:0010616) help
..expandNeoplasm of the tracheobronchial system (HP:0100552) help
..expandPulmonary chondroma (HP:0031474) help
..expandPulmonary lymphangiomyomatosis (HP:0012798) help
..expandPulmonary lymphoma (HP:0011953) help
..expandPulmonary paraglioma (HP:0100636) help
..expandSmall cell lung carcinoma (HP:0030357) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0030358HP:0030358Non-small cell lung carcinoma0BAP1 CL E G H8314950OMIM:614327Tumor predisposition syndrome184
HP:0030358HP:0030358Non-small cell lung carcinoma0BRAF CL E G H6731097OMIM:211980Lung cancer, susceptibility to.276
HP:0030358HP:0030358Non-small cell lung carcinoma0CASP8 CL E G H8411509OMIM:211980Lung cancer, susceptibility to.37
HP:0030358HP:0030358Non-small cell lung carcinoma0CDKN2A CL E G H10291787ORPHA:1501Adrenocortical carcinoma289
HP:0030358HP:0030358Non-small cell lung carcinoma0CTNNB1 CL E G H14992514ORPHA:1501Adrenocortical carcinoma88
HP:0030358HP:0030358Non-small cell lung carcinoma0CYP2A6 CL E G H15482610OMIM:211980Lung cancer, susceptibility to.6
HP:0030358HP:0030358Non-small cell lung carcinoma0EGFR CL E G H19563236OMIM:211980Lung cancer, susceptibility to.257
HP:0030358HP:0030358Non-small cell lung carcinoma0ERBB2 CL E G H20643430OMIM:211980Lung cancer, susceptibility to.77
HP:0030358HP:0030358Non-small cell lung carcinoma0ERCC6 CL E G H20743438OMIM:211980Lung cancer, susceptibility to.199
HP:0030358HP:0030358Non-small cell lung carcinoma0FASLG CL E G H35611936OMIM:211980Lung cancer, susceptibility to.37
HP:0030358HP:0030358Non-small cell lung carcinoma0IRF1 CL E G H36596116OMIM:211980Lung cancer, susceptibility to.2
HP:0030358HP:0030358Non-small cell lung carcinoma0KRAS CL E G H38456407OMIM:211980Lung cancer, susceptibility to.196
HP:0030358HP:0030358Non-small cell lung carcinoma0MAP3K8 CL E G H13266860OMIM:211980Lung cancer, susceptibility to.
HP:0030358HP:0030358Non-small cell lung carcinoma0NDUFAF6 CL E G H13768228625OMIM:618913FANCONI RENOTUBULAR SYNDROME 5; FRTS539
HP:0030358HP:0030358Non-small cell lung carcinoma0PIK3CA CL E G H52908975OMIM:211980Lung cancer, susceptibility to.162
HP:0030358HP:0030358Non-small cell lung carcinoma0PPP2R1B CL E G H55199303OMIM:211980Lung cancer, susceptibility to.1
HP:0030358HP:0030358Non-small cell lung carcinoma0PRKAR1A CL E G H55739388ORPHA:1501Adrenocortical carcinoma134
HP:0030358HP:0030358Non-small cell lung carcinoma0PRKN CL E G H50718607OMIM:211980Lung cancer, susceptibility to.138
HP:0030358HP:0030358Non-small cell lung carcinoma0SLC22A18 CL E G H500210964OMIM:211980Lung cancer, susceptibility to.3
HP:0030358HP:0030358Non-small cell lung carcinoma0SPRED1 CL E G H16174220249ORPHA:137605Legius syndrome136
HP:0030358HP:0030358Non-small cell lung carcinoma0TERT CL E G H701511730ORPHA:1501Adrenocortical carcinoma238
HP:0030358HP:0030358Non-small cell lung carcinoma0TP53 CL E G H715711998ORPHA:1501Adrenocortical carcinoma911
HP:0030358HP:0030358Non-small cell lung carcinoma0TP53 CL E G H715711998OMIM:151623Li-Fraumeni syndrome911
HP:0030358HP:0030358Non-small cell lung carcinoma0ZNRF3 CL E G H8413318126ORPHA:1501Adrenocortical carcinoma
HP:0030358HP:0030360Large cell lung carcinoma1 CL E G H
HP:0030358HP:0030359Squamous cell lung carcinoma1 CL E G H
HP:0030358HP:0030078Lung adenocarcinoma1BAP1 CL E G H8314950OMIM:614327Tumor predisposition syndrome.184
HP:0030358HP:0030078Lung adenocarcinoma1BRAF CL E G H6731097OMIM:211980Lung cancer, susceptibility to.276
HP:0030358HP:0030078Lung adenocarcinoma1CASP8 CL E G H8411509OMIM:211980Lung cancer, susceptibility to.37
HP:0030358HP:0030078Lung adenocarcinoma1CDKN2A CL E G H10291787ORPHA:1501Adrenocortical carcinomaHP:0040282 - Frequent289
HP:0030358HP:0030078Lung adenocarcinoma1CTNNB1 CL E G H14992514ORPHA:1501Adrenocortical carcinomaHP:0040282 - Frequent88
HP:0030358HP:0030078Lung adenocarcinoma1CYP2A6 CL E G H15482610OMIM:211980Lung cancer, susceptibility to.6
HP:0030358HP:0030078Lung adenocarcinoma1EGFR CL E G H19563236OMIM:211980Lung cancer, susceptibility to.257
HP:0030358HP:0030078Lung adenocarcinoma1ERBB2 CL E G H20643430OMIM:211980Lung cancer, susceptibility to.77
HP:0030358HP:0030078Lung adenocarcinoma1ERCC6 CL E G H20743438OMIM:211980Lung cancer, susceptibility to.199
HP:0030358HP:0030078Lung adenocarcinoma1FASLG CL E G H35611936OMIM:211980Lung cancer, susceptibility to.37
HP:0030358HP:0030078Lung adenocarcinoma1IRF1 CL E G H36596116OMIM:211980Lung cancer, susceptibility to.2
HP:0030358HP:0030078Lung adenocarcinoma1KRAS CL E G H38456407OMIM:211980Lung cancer, susceptibility to.196
HP:0030358HP:0030078Lung adenocarcinoma1MAP3K8 CL E G H13266860OMIM:211980Lung cancer, susceptibility to.
HP:0030358HP:0030078Lung adenocarcinoma1NDUFAF6 CL E G H13768228625OMIM:618913FANCONI RENOTUBULAR SYNDROME 5; FRTS539
HP:0030358HP:0030078Lung adenocarcinoma1PIK3CA CL E G H52908975OMIM:211980Lung cancer, susceptibility to.162
HP:0030358HP:0030078Lung adenocarcinoma1PPP2R1B CL E G H55199303OMIM:211980Lung cancer, susceptibility to.1
HP:0030358HP:0030078Lung adenocarcinoma1PRKAR1A CL E G H55739388ORPHA:1501Adrenocortical carcinomaHP:0040282 - Frequent134
HP:0030358HP:0030078Lung adenocarcinoma1PRKN CL E G H50718607OMIM:211980Lung cancer, susceptibility to.138
HP:0030358HP:0030078Lung adenocarcinoma1SLC22A18 CL E G H500210964OMIM:211980Lung cancer, susceptibility to.3
HP:0030358HP:0030078Lung adenocarcinoma1TERT CL E G H701511730ORPHA:1501Adrenocortical carcinomaHP:0040282 - Frequent238
HP:0030358HP:0030078Lung adenocarcinoma1TP53 CL E G H715711998ORPHA:1501Adrenocortical carcinomaHP:0040282 - Frequent911
HP:0030358HP:0030078Lung adenocarcinoma1TP53 CL E G H715711998OMIM:151623Li-Fraumeni syndrome.911
HP:0030358HP:0030078Lung adenocarcinoma1ZNRF3 CL E G H8413318126ORPHA:1501Adrenocortical carcinomaHP:0040282 - Frequent


Genes (23) :BAP1 BRAF CASP8 CDKN2A CTNNB1 CYP2A6 EGFR ERBB2 ERCC6 FASLG IRF1 KRAS MAP3K8 NDUFAF6 PIK3CA PPP2R1B PRKAR1A PRKN SLC22A18 SPRED1 TERT TP53 ZNRF3

Diseases (6) :OMIM:614327 OMIM:211980 ORPHA:1501 OMIM:618913 ORPHA:137605 OMIM:151623
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.