Human Phenotype Ontology 
Grandparent Node:
expandAbnormal retinal morphology (HP:0000479)help
Grandparent Node:
expandAbnormality of the vasculature of the eye (HP:0008047)help
Parent Node:
expandAbnormal retinal vascular morphology (HP:0008046)help
..Starting node
..expandAttenuation of retinal blood vessels (HP:0007843)help
Term ID: 7843
Name: Attenuation of retinal blood vessels
Synonym: Narrowing of blood vessels in back of eye
Definition:
Comments:
Reference: HP:0007843
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal distribution of retinal arterioles and venules (HP:0007815) help
..expandAbnormal retinal artery morphology (HP:0000630) help
..expandHypertensive retinopathy (HP:0001095) help
..expandIncreased retinal vascularity (HP:0007986) help
..expandLipemia retinalis (HP:0000660) help
..expandPeripheral retinal avascularization (HP:0007685) help
..expandRetinal neovascularization (HP:0030666) help
..expandRetinal telangiectasia (HP:0007763) help
..expandRetinal vascular malformation (HP:0007797) help
..expandRetinal vascular proliferation (HP:0007850) help
..expandRetinal vascular tortuosity (HP:0012841) help
..expandRetinal vasculitis (HP:0025188) help
..expandRetinal vein occlusion (HP:0012636) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007843HP:0007843Attenuation of retinal blood vessels0ABCA4 CL E G H2434OMIM:604116CONE-ROD DYSTROPHY 3; CORD3826
HP:0007843HP:0007843Attenuation of retinal blood vessels0ABCA4 CL E G H2434OMIM:601718Retinitis pigmentosa 19.826
HP:0007843HP:0007843Attenuation of retinal blood vessels0AGBL5 CL E G H6050926147OMIM:617023Retinitis pigmentosa 752
HP:0007843HP:0007843Attenuation of retinal blood vessels0AIPL1 CL E G H23746359OMIM:604393Leber congenital amaurosis 4.114
HP:0007843HP:0007843Attenuation of retinal blood vessels0ARL3 CL E G H403694OMIM:618173RETINITIS PIGMENTOSA 83; RP831
HP:0007843HP:0007843Attenuation of retinal blood vessels0ARL6 CL E G H8410013210OMIM:209900Bardet-Biedl syndrome 129
HP:0007843HP:0007843Attenuation of retinal blood vessels0ATF6 CL E G H22926791ORPHA:49382AchromatopsiaHP:0040283 - Occasional10
HP:0007843HP:0007843Attenuation of retinal blood vessels0BBS1 CL E G H582966OMIM:209900Bardet-Biedl syndrome 1114
HP:0007843HP:0007843Attenuation of retinal blood vessels0BBS9 CL E G H2724130000OMIM:615986BARDET-BIEDL SYNDROME 9; BBS9119
HP:0007843HP:0007843Attenuation of retinal blood vessels0BEST1 CL E G H743912703OMIM:613194Retinitis pigmentosa-50182
HP:0007843HP:0007843Attenuation of retinal blood vessels0CCDC28B CL E G H7914028163OMIM:209900Bardet-Biedl syndrome 14
HP:0007843HP:0007843Attenuation of retinal blood vessels0CDHR1 CL E G H9221114550OMIM:613660CONE-ROD DYSTROPHY 15; CORD15147
HP:0007843HP:0007843Attenuation of retinal blood vessels0CERKL CL E G H37529821699OMIM:608380Retinitis pigmentosa 2671
HP:0007843HP:0007843Attenuation of retinal blood vessels0CFAP418 CL E G H15765727232OMIM:614500Cone-Rod dystrophy 16
HP:0007843HP:0007843Attenuation of retinal blood vessels0CHM CL E G H11211940OMIM:303100CHOROIDEREMIA47
HP:0007843HP:0007843Attenuation of retinal blood vessels0CLCC1 CL E G H2315529675OMIM:609913RETINITIS PIGMENTOSA 32; RP32
HP:0007843HP:0007843Attenuation of retinal blood vessels0CLRN1 CL E G H740112605OMIM:614180Retinitis pigmentosa 6160
HP:0007843HP:0007843Attenuation of retinal blood vessels0CNGA1 CL E G H12592148OMIM:613756RETINITIS PIGMENTOSA 49; RP4944
HP:0007843HP:0007843Attenuation of retinal blood vessels0CNGA3 CL E G H12612150ORPHA:49382AchromatopsiaHP:0040283 - Occasional82
HP:0007843HP:0007843Attenuation of retinal blood vessels0CNGB3 CL E G H547142153ORPHA:49382AchromatopsiaHP:0040283 - Occasional194
HP:0007843HP:0007843Attenuation of retinal blood vessels0CNNM4 CL E G H26504105OMIM:217080Jalili syndrome61
HP:0007843HP:0007843Attenuation of retinal blood vessels0COL18A1 CL E G H807812195OMIM:267750Knobloch syndrome 1177
HP:0007843HP:0007843Attenuation of retinal blood vessels0CRB1 CL E G H234182343OMIM:600105Retinitis pigmentosa 12156
HP:0007843HP:0007843Attenuation of retinal blood vessels0ERCC4 CL E G H20723436OMIM:610965XFE progeroid syndrome158
HP:0007843HP:0007843Attenuation of retinal blood vessels0EYS CL E G H34600721555OMIM:602772Retinitis pigmentosa 25209
HP:0007843HP:0007843Attenuation of retinal blood vessels0FLVCR1 CL E G H2898224682OMIM:609033Ataxia, posterior column, with retinitis pigmentosa111
HP:0007843HP:0007843Attenuation of retinal blood vessels0FSCN2 CL E G H257943960OMIM:607921RETINITIS PIGMENTOSA 30; RP3026
HP:0007843HP:0007843Attenuation of retinal blood vessels0GGCX CL E G H26774247ORPHA:436274Pseudoxanthoma elasticum-like skin manifestations with retinitis pigmentosaHP:0040281 - Very frequent129
HP:0007843HP:0007843Attenuation of retinal blood vessels0GNAT2 CL E G H27804394ORPHA:49382AchromatopsiaHP:0040283 - Occasional19
HP:0007843HP:0007843Attenuation of retinal blood vessels0GUCY2D CL E G H30004689OMIM:601777Cone-Rod dystrophy 6124
HP:0007843HP:0007843Attenuation of retinal blood vessels0GUCY2D CL E G H30004689OMIM:204000Leber congenital amaurosis, type I124
HP:0007843HP:0007843Attenuation of retinal blood vessels0HK1 CL E G H30984922OMIM:617460Retinitis pigmentosa 7911
HP:0007843HP:0007843Attenuation of retinal blood vessels0HLA-A CL E G H31054931ORPHA:179Birdshot chorioretinopathyHP:0040282 - Frequent4
HP:0007843HP:0007843Attenuation of retinal blood vessels0IDH3A CL E G H34195384OMIM:619007RETINITIS PIGMENTOSA 90; RP90
HP:0007843HP:0007843Attenuation of retinal blood vessels0IDH3B CL E G H34205385OMIM:612572RETINITIS PIGMENTOSA 46; RP4630
HP:0007843HP:0007843Attenuation of retinal blood vessels0IFT140 CL E G H974229077OMIM:617781Retinitis pigmentosa 80148
HP:0007843HP:0007843Attenuation of retinal blood vessels0IFT140 CL E G H974229077OMIM:266920Short-rib thoracic dysplasia 9 with or without polydactyly148
HP:0007843HP:0007843Attenuation of retinal blood vessels0IFT172 CL E G H2616030391OMIM:616394Retinitis pigmentosa 71.48
HP:0007843HP:0007843Attenuation of retinal blood vessels0IMPDH1 CL E G H36146052OMIM:180105Retinitis pigmentosa 1052
HP:0007843HP:0007843Attenuation of retinal blood vessels0IMPG2 CL E G H5093918362OMIM:613581RETINITIS PIGMENTOSA 56; RP56120
HP:0007843HP:0007843Attenuation of retinal blood vessels0KIAA1549 CL E G H5767022219OMIM:618613RETINITIS PIGMENTOSA 86; RP86
HP:0007843HP:0007843Attenuation of retinal blood vessels0LCA5 CL E G H16769131923ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040282 - Frequent70
HP:0007843HP:0007843Attenuation of retinal blood vessels0LRAT CL E G H92276685ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040282 - Frequent62
HP:0007843HP:0007843Attenuation of retinal blood vessels0MAK CL E G H41176816OMIM:614181Retinitis pigmentosa 6253
HP:0007843HP:0007843Attenuation of retinal blood vessels0MKS1 CL E G H549037121OMIM:615990BARDET-BIEDL SYNDROME 13; BBS13127
HP:0007843HP:0007843Attenuation of retinal blood vessels0MVK CL E G H45987530OMIM:610377Mevalonic aciduria150
HP:0007843HP:0007843Attenuation of retinal blood vessels0NMNAT1 CL E G H6480217877OMIM:608553Leber congenital amaurosis 9.15
HP:0007843HP:0007843Attenuation of retinal blood vessels0NMNAT1 CL E G H6480217877OMIM:619260SPONDYLOEPIPHYSEAL DYSPLASIA, SENSORINEURAL HEARING LOSS, IMPAIRED INTELLECTUAL DEVELOPMENT, AND LEBER CONGENITAL AMAUROSIS; SHILCA15
HP:0007843HP:0007843Attenuation of retinal blood vessels0OFD1 CL E G H84812567OMIM:300424Retinitis pigmentosa 23201
HP:0007843HP:0007843Attenuation of retinal blood vessels0PCARE CL E G H38893934383OMIM:613428Retinitis pigmentosa 54.
HP:0007843HP:0007843Attenuation of retinal blood vessels0PDE6A CL E G H51458785OMIM:613810RETINITIS PIGMENTOSA 43; RP43116
HP:0007843HP:0007843Attenuation of retinal blood vessels0PDE6B CL E G H51588786OMIM:613801Retinitis pigmentosa 40126
HP:0007843HP:0007843Attenuation of retinal blood vessels0PDE6C CL E G H51468787ORPHA:49382AchromatopsiaHP:0040283 - Occasional80
HP:0007843HP:0007843Attenuation of retinal blood vessels0PDE6G CL E G H51488789OMIM:613582Retinitis pigmentosa 57.18
HP:0007843HP:0007843Attenuation of retinal blood vessels0PDE6H CL E G H51498790ORPHA:49382AchromatopsiaHP:0040283 - Occasional14
HP:0007843HP:0007843Attenuation of retinal blood vessels0PRCD CL E G H76820632528OMIM:610599Retinitis pigmentosa 36.39
HP:0007843HP:0007843Attenuation of retinal blood vessels0PROM1 CL E G H88429454OMIM:612095RETINITIS PIGMENTOSA 41; RP41110
HP:0007843HP:0007843Attenuation of retinal blood vessels0PRPF8 CL E G H1059417340OMIM:600059Retinitis pigmentosa 1394
HP:0007843HP:0007843Attenuation of retinal blood vessels0PRPH2 CL E G H59619942OMIM:608133Retinitis pigmentosa 7159
HP:0007843HP:0007843Attenuation of retinal blood vessels0PRPH2 CL E G H59619942ORPHA:52427Retinitis punctata albescensHP:0040282 - Frequent159
HP:0007843HP:0007843Attenuation of retinal blood vessels0RAX2 CL E G H8483918286OMIM:62010252
HP:0007843HP:0007843Attenuation of retinal blood vessels0RDH12 CL E G H14522619977OMIM:612712Leber congenital amaurosis 1345
HP:0007843HP:0007843Attenuation of retinal blood vessels0RDH5 CL E G H59599940ORPHA:52427Retinitis punctata albescensHP:0040282 - Frequent32
HP:0007843HP:0007843Attenuation of retinal blood vessels0RGR CL E G H59959990OMIM:613769RETINITIS PIGMENTOSA 44; RP4428
HP:0007843HP:0007843Attenuation of retinal blood vessels0RHO CL E G H601010012OMIM:613731Retinitis pigmentosa 4107
HP:0007843HP:0007843Attenuation of retinal blood vessels0RHO CL E G H601010012ORPHA:52427Retinitis punctata albescensHP:0040282 - Frequent107
HP:0007843HP:0007843Attenuation of retinal blood vessels0RLBP1 CL E G H601710024ORPHA:52427Retinitis punctata albescensHP:0040282 - Frequent47
HP:0007843HP:0007843Attenuation of retinal blood vessels0ROM1 CL E G H609410254OMIM:608133Retinitis pigmentosa 738
HP:0007843HP:0007843Attenuation of retinal blood vessels0RP1 CL E G H610110263OMIM:180100Retinitis pigmentosa 1111
HP:0007843HP:0007843Attenuation of retinal blood vessels0RP1L1 CL E G H9413715946OMIM:618826RETINITIS PIGMENTOSA 88; RP88284
HP:0007843HP:0007843Attenuation of retinal blood vessels0RPE65 CL E G H612110294OMIM:204100Leber congenital amaurosis, type II129
HP:0007843HP:0007843Attenuation of retinal blood vessels0RPE65 CL E G H612110294OMIM:613794Retinitis pigmentosa 20.129
HP:0007843HP:0007843Attenuation of retinal blood vessels0RPE65 CL E G H612110294ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040282 - Frequent129
HP:0007843HP:0007843Attenuation of retinal blood vessels0RPGR CL E G H610310295ORPHA:49382AchromatopsiaHP:0040283 - Occasional200
HP:0007843HP:0007843Attenuation of retinal blood vessels0RPGRIP1 CL E G H5709613436OMIM:613826Leber congenital amaurosis 6.109
HP:0007843HP:0007843Attenuation of retinal blood vessels0RTTN CL E G H2591418654ORPHA:468631Microcephalic cortical malformations-short stature due to RTTN deficiencyHP:0040283 - Occasional113
HP:0007843HP:0007843Attenuation of retinal blood vessels0SCAPER CL E G H4985513081OMIM:618195Intellectual developmental disorder and retinitis pigmentosa
HP:0007843HP:0007843Attenuation of retinal blood vessels0SEMA4A CL E G H6421810729OMIM:610283Cone-Rod dystrophy 1048
HP:0007843HP:0007843Attenuation of retinal blood vessels0SLC6A6 CL E G H653311052OMIM:145350Hypotaurinemic retinal degeneration and cardiomyopathy
HP:0007843HP:0007843Attenuation of retinal blood vessels0SNRNP200 CL E G H2302030859OMIM:610359Retinitis pigmentosa 3383
HP:0007843HP:0007843Attenuation of retinal blood vessels0SPATA7 CL E G H5581220423ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040282 - Frequent48
HP:0007843HP:0007843Attenuation of retinal blood vessels0TLCD3B CL E G H8372325295OMIM:619531CONE-ROD DYSTROPHY 22; CORD22
HP:0007843HP:0007843Attenuation of retinal blood vessels0TOPORS CL E G H1021021653OMIM:609923Retinitis pigmentosa 3161
HP:0007843HP:0007843Attenuation of retinal blood vessels0TTC8 CL E G H12301620087OMIM:613464Retinitis pigmentosa 51.41
HP:0007843HP:0007843Attenuation of retinal blood vessels0TUB CL E G H727512406OMIM:616188Retinal dystrophy and obesity1
HP:0007843HP:0007843Attenuation of retinal blood vessels0USH2A CL E G H739912601OMIM:613809Retinitis pigmentosa 39.777
HP:0007843HP:0007843Attenuation of retinal blood vessels0USP45 CL E G H8501520080OMIM:618513LEBER CONGENITAL AMAUROSIS 19; LCA19
HP:0007843HP:0007843Attenuation of retinal blood vessels0WDR19 CL E G H5772818340OMIM:614376Short-Rib thoracic dysplasia 5 with or without polydactyly95
HP:0007843HP:0007843Attenuation of retinal blood vessels0ZNF408 CL E G H7979720041OMIM:616469Retinitis pigmentosa 7214
HP:0007843HP:0007843Attenuation of retinal blood vessels0ZNF513 CL E G H13055726498OMIM:613617Retinitis pigmentosa 58.27


Genes (82) :ABCA4 AGBL5 AIPL1 ARL3 ARL6 ATF6 BBS1 BBS9 BEST1 CCDC28B CDHR1 CERKL CFAP418 CHM CLCC1 CLRN1 CNGA1 CNGA3 CNGB3 CNNM4 COL18A1 CRB1 ERCC4 EYS FLVCR1 FSCN2 GGCX GNAT2 GUCY2D HK1 HLA-A IDH3A IDH3B IFT140 IFT172 IMPDH1 IMPG2 KIAA1549 LCA5 LRAT MAK MKS1 MVK NMNAT1 OFD1 PCARE PDE6A PDE6B PDE6C PDE6G PDE6H PRCD PROM1 PRPF8 PRPH2 RAX2 RDH12 RDH5 RGR RHO RLBP1 ROM1 RP1 RP1L1 RPE65 RPGR RPGRIP1 RTTN SCAPER SEMA4A SLC6A6 SNRNP200 SPATA7 TLCD3B TOPORS TTC8 TUB USH2A USP45 WDR19 ZNF408 ZNF513

Diseases (75) :OMIM:604116 OMIM:601718 OMIM:617023 OMIM:604393 OMIM:618173 OMIM:209900 ORPHA:49382 OMIM:615986 OMIM:613194 OMIM:613660 OMIM:608380 OMIM:614500 OMIM:303100 OMIM:609913 OMIM:614180 OMIM:613756 OMIM:217080 OMIM:267750 OMIM:600105 OMIM:610965 OMIM:602772 OMIM:609033 OMIM:607921 ORPHA:436274 OMIM:601777 OMIM:204000 OMIM:617460 ORPHA:179 OMIM:619007 OMIM:612572 OMIM:617781 OMIM:266920 OMIM:616394 OMIM:180105 OMIM:613581 OMIM:618613 ORPHA:364055 OMIM:614181 OMIM:615990 OMIM:610377 OMIM:608553 OMIM:619260 OMIM:300424 OMIM:613428 OMIM:613810 OMIM:613801 OMIM:613582 OMIM:610599 OMIM:612095 OMIM:600059 OMIM:608133 ORPHA:52427 OMIM:620102 OMIM:612712 OMIM:613769 OMIM:613731 OMIM:180100 OMIM:618826 OMIM:204100 OMIM:613794 OMIM:613826 ORPHA:468631 OMIM:618195 OMIM:610283 OMIM:145350 OMIM:610359 OMIM:619531 OMIM:609923 OMIM:613464 OMIM:616188 OMIM:613809 OMIM:618513 OMIM:614376 OMIM:616469 OMIM:613617
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.