Human Phenotype Ontology 
Grandparent Node:
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Abnormally lax or hyperextensible skin (HP:0008067)help
Grandparent Node:
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Premature skin wrinkling (HP:0100678)help
Parent Node:
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Abnormal skin morphology of the palm (HP:0040211)help
Parent Node:
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Excessive wrinkled skin (HP:0007392)help
..Starting node
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Excessive wrinkling of palmar skin (HP:0007605)help
Term ID: 7605
Name: Excessive wrinkling of palmar skin
Synonym: Redundant, wrinkled skin of palms
Definition:
Comments:
Reference: HP:0007605
Genes and Diseases:
 
       Child Nodes:
........expandPalmoplantar cutis laxa (HP:0007517) help

 Sister Nodes: 
..expandExcessive skin wrinkling on dorsum of hands and fingers (HP:0007407) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007605HP:0007605Excessive wrinkling of palmar skin0ATP6V0A2 CL E G H2354518481OMIM:278250Wrinkly skin syndrome140
HP:0007605HP:0007605Excessive wrinkling of palmar skin0C1R CL E G H7151246OMIM:130080Ehlers-Danlos syndrome, periodontal type, 115
HP:0007605HP:0007605Excessive wrinkling of palmar skin0CSTA CL E G H14752481ORPHA:263534Acral peeling skin syndromeHP:0040283 - Occasional4
HP:0007605HP:0007605Excessive wrinkling of palmar skin0FGFR2 CL E G H22633689OMIM:123790Beare-Stevenson cutis gyrata syndrome175
HP:0007605HP:0007605Excessive wrinkling of palmar skin0LZTR1 CL E G H82166742OMIM:616564Noonan syndrome 1043
HP:0007605HP:0007605Excessive wrinkling of palmar skin0LZTR1 CL E G H82166742OMIM:605275Noonan syndrome 243
HP:0007605HP:0007605Excessive wrinkling of palmar skin0MRAS CL E G H228087227OMIM:618499NOONAN SYNDROME 11; NS11
HP:0007605HP:0007605Excessive wrinkling of palmar skin0PLOD1 CL E G H53519081OMIM:225400Ehlers-Danlos syndrome, kyphoscoliotic type, 1105
HP:0007605HP:0007605Excessive wrinkling of palmar skin0RIT1 CL E G H601610023OMIM:615355NOONAN SYNDROME 8; NS839
HP:0007605HP:0007605Excessive wrinkling of palmar skin0TBL1XR1 CL E G H7971829529ORPHA:487825Pierpont syndromeHP:0040282 - Frequent22
HP:0007605HP:0007605Excessive wrinkling of palmar skin0TGM5 CL E G H933311781ORPHA:263534Acral peeling skin syndromeHP:0040283 - Occasional44
HP:0007605HP:0007605Excessive wrinkling of palmar skin0ZNF469 CL E G H8462723216OMIM:229200Brittle cornea syndrome397
HP:0007605HP:0007517Palmoplantar cutis laxa1ATP6V0A2 CL E G H2354518481OMIM:278250Wrinkly skin syndrome.140
HP:0007605HP:0007517Palmoplantar cutis laxa1C1R CL E G H7151246OMIM:130080Ehlers-Danlos syndrome, periodontal type, 1.15
HP:0007605HP:0007517Palmoplantar cutis laxa1FGFR2 CL E G H22633689OMIM:123790Beare-Stevenson cutis gyrata syndrome.175
HP:0007605HP:0007517Palmoplantar cutis laxa1LZTR1 CL E G H82166742OMIM:616564Noonan syndrome 1043
HP:0007605HP:0007517Palmoplantar cutis laxa1LZTR1 CL E G H82166742OMIM:605275Noonan syndrome 243
HP:0007605HP:0007517Palmoplantar cutis laxa1MRAS CL E G H228087227OMIM:618499NOONAN SYNDROME 11; NS11
HP:0007605HP:0007517Palmoplantar cutis laxa1PLOD1 CL E G H53519081OMIM:225400Ehlers-Danlos syndrome, kyphoscoliotic type, 1.105
HP:0007605HP:0007517Palmoplantar cutis laxa1RIT1 CL E G H601610023OMIM:615355NOONAN SYNDROME 8; NS839
HP:0007605HP:0007517Palmoplantar cutis laxa1ZNF469 CL E G H8462723216OMIM:229200Brittle cornea syndrome.397


Genes (11) :ATP6V0A2 C1R CSTA FGFR2 LZTR1 MRAS PLOD1 RIT1 TBL1XR1 TGM5 ZNF469

Diseases (11) :OMIM:278250 OMIM:130080 ORPHA:263534 OMIM:123790 OMIM:616564 OMIM:605275 OMIM:618499 OMIM:225400 OMIM:615355 ORPHA:487825 OMIM:229200
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.