Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of immune system physiology (HP:0010978)help
Parent Node:
expandRecurrent infections (HP:0002719)help
..Starting node
..expandRecurrent protozoan infections (HP:0005386)help
Term ID: 5386
Name: Recurrent protozoan infections
Synonym:
Definition: Increased susceptibility to protozoan infections, as manifested by recurrent episodes of protozoan infection.
Comments:
Reference: HP:0005386
Genes and Diseases:
 
       Child Nodes:
........expandTegumentary leishmaniasis susceptibility (HP:0007408) help

 Sister Nodes: 
..expandFailure to thrive secondary to recurrent infections (HP:0008866) help
..expandRecurrent abscess formation (HP:0002722) help
..expandRecurrent bacterial infections (HP:0002718) help
..expandRecurrent ear infections (HP:0410018) help
..expandRecurrent fungal infections (HP:0002841) help
..expandRecurrent infection of the gastrointestinal tract (HP:0004798) help
..expandRecurrent infections in infancy and early childhood (HP:0005437) help
..expandRecurrent infections of the middle ear (HP:0040268) help
..expandRecurrent opportunistic infections (HP:0005390) help
..expandRecurrent otitis media (HP:0000403) help
..expandRecurrent parasitic infections (HP:0030885) help
..expandRecurrent respiratory infections (HP:0002205) help
..expandRecurrent urinary tract infections (HP:0000010) help
..expandRecurrent viral infections (HP:0004429) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0005386HP:0005386Recurrent protozoan infections0CIITA CL E G H42617067OMIM:209920Bare lymphocyte syndrome, type II.118
HP:0005386HP:0005386Recurrent protozoan infections0CIITA CL E G H42617067ORPHA:572Immunodeficiency by defective expression of MHC class IIHP:0040282 - Frequent118
HP:0005386HP:0005386Recurrent protozoan infections0IL12RB1 CL E G H35945971ORPHA:319552Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency46
HP:0005386HP:0005386Recurrent protozoan infections0RFX5 CL E G H59939986OMIM:209920Bare lymphocyte syndrome, type II.38
HP:0005386HP:0005386Recurrent protozoan infections0RFX5 CL E G H59939986ORPHA:572Immunodeficiency by defective expression of MHC class IIHP:0040282 - Frequent38
HP:0005386HP:0005386Recurrent protozoan infections0RFXANK CL E G H86259987OMIM:209920Bare lymphocyte syndrome, type II.26
HP:0005386HP:0005386Recurrent protozoan infections0RFXANK CL E G H86259987ORPHA:572Immunodeficiency by defective expression of MHC class IIHP:0040282 - Frequent26
HP:0005386HP:0005386Recurrent protozoan infections0RFXAP CL E G H59949988OMIM:209920Bare lymphocyte syndrome, type II.34
HP:0005386HP:0005386Recurrent protozoan infections0RFXAP CL E G H59949988ORPHA:572Immunodeficiency by defective expression of MHC class IIHP:0040282 - Frequent34
HP:0005386HP:0007408Tegumentary leishmaniasis susceptibility1IL12RB1 CL E G H35945971ORPHA:319552Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiencyHP:0040283 - Occasional46


Genes (5) :CIITA IL12RB1 RFX5 RFXANK RFXAP

Diseases (3) :OMIM:209920 ORPHA:572 ORPHA:319552
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.