Human Phenotype Ontology 
Grandparent Node:
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Abnormal autonomic nervous system physiology (HP:0012332)help
Grandparent Node:
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Hypotension (HP:0002615)help
Parent Node:
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Orthostatic hypotension (HP:0001278)help
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Orthostatic hypotension due to autonomic dysfunction (HP:0004926)help
Term ID: 4926
Name: Orthostatic hypotension due to autonomic dysfunction
Synonym:
Definition:
Comments:
Reference: HP:0004926
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandPostural hypotension with compensatory tachycardia (HP:0005307) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0ARSA CL E G H410713ORPHA:309271Metachromatic leukodystrophy, adult formHP:0040284 - Very rare253
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0COQ2 CL E G H2723525223ORPHA:227510Multiple system atrophy, cerebellar typeHP:0040282 - Frequent54
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0COQ2 CL E G H2723525223ORPHA:98933Multiple system atrophy, parkinsonian typeHP:0040282 - Frequent54
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0DNAJC13 CL E G H2331730343ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional2
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0EIF4G1 CL E G H19813296ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional2
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0GBA1 CL E G H26294177ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0GIGYF2 CL E G H2605811960ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional8
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0GSN CL E G H29344620ORPHA:85448AGel amyloidosisHP:0040283 - Occasional53
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0LEP CL E G H39526553ORPHA:66628Obesity due to congenital leptin deficiencyHP:0040282 - Frequent47
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0LEPR CL E G H39536554ORPHA:179494Obesity due to leptin receptor gene deficiencyHP:0040282 - Frequent46
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0LMNB1 CL E G H40016637OMIM:169500Leukodystrophy, adult-onset, autosomal dominant44
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0LRRK2 CL E G H12089218618ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional221
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0NTRK1 CL E G H49148031ORPHA:642Hereditary sensory and autonomic neuropathy type 4HP:0040283 - Occasional97
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0PSAP CL E G H56609498ORPHA:309271Metachromatic leukodystrophy, adult formHP:0040284 - Very rare81
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0SNCA CL E G H662211138ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional65
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0TTR CL E G H727612405OMIM:105210Amyloidosis, hereditary, transthyretin-related.107
HP:0004926HP:0004926Orthostatic hypotension due to autonomic dysfunction0VPS35 CL E G H5573713487ORPHA:411602Hereditary late-onset Parkinson diseaseHP:0040283 - Occasional37


Genes (16) :ARSA COQ2 DNAJC13 EIF4G1 GBA1 GIGYF2 GSN LEP LEPR LMNB1 LRRK2 NTRK1 PSAP SNCA TTR VPS35

Diseases (10) :ORPHA:309271 ORPHA:227510 ORPHA:98933 ORPHA:411602 ORPHA:85448 ORPHA:66628 ORPHA:179494 OMIM:169500 ORPHA:642 OMIM:105210
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.