Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal liver morphology (HP:0410042)

Grandparent Node:
Increased inflammatory response (HP:0012649)

Parent Node:
Fulminant hepatic failure (HP:0004448)

Parent Node:
Hepatitis (HP:0012115)

..Starting node
..Fulminant hepatitis (HP:0004787)

Term ID:

4787

Name:

Fulminant hepatitis

Synonym:

Definition:

Acute hepatitis complicated by acute liver failure with hepatic encephalopathy occurring less than 8 weeks after the onset of jaundice.

Comments:

Reference:

HP:0004787

Genes and Diseases:

Child Nodes:

Sister Nodes:

Acute hepatitis (HP:0200119)

Atypical or prolonged hepatitis (HP:0200122)

Chronic hepatitis (HP:0200123)

Giant cell hepatitis (HP:0200084)

Viral hepatitis (HP:0006562)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004787	HP:0004787	Fulminant hepatitis	0	IL18BP CL E G H	10068	5987	OMIM:618549	HEPATITIS, FULMINANT VIRAL, SUSCEPTIBILITY TO; FVH
HP:0004787	HP:0004787	Fulminant hepatitis	0	KRT18 CL E G H	3875	6430	OMIM:215600	Cirrhosis, familial	19
HP:0004787	HP:0004787	Fulminant hepatitis	0	SH2D1A CL E G H	4068	10820	OMIM:308240	Lymphoproliferative syndrome, X-linked, 1	37
HP:0004787	HP:0004787	Fulminant hepatitis	0	XIAP CL E G H	331	592	OMIM:308240	Lymphoproliferative syndrome, X-linked, 1	81

Genes (4) :IL18BP KRT18 SH2D1A XIAP

Diseases (3) :OMIM:618549 OMIM:215600 OMIM:308240

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.