Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Upper motor neuron dysfunction (HP:0002493)

Parent Node:
Weakness due to upper motor neuron dysfunction (HP:0010549)

..Starting node
..Hemiplegia/hemiparesis (HP:0004374)

Term ID:

4374

Name:

Hemiplegia/hemiparesis

Synonym:

Paralysis or weakness of one side of body

Definition:

Loss of strength in the arm, leg, and sometimes face on one side of the body. Hemiplegia refers to a severe or complete loss of strength, whereas hemiparesis refers to a relatively mild loss of strength.

Comments:

Reference:

HP:0004374

Genes and Diseases:

Child Nodes:

........

Hemiparesis (HP:0001269)

........

Hemiplegia (HP:0002301)

................... HP:0012194 Episodic hemiplegia
................... HP:0040292 Left hemiplegia
................... HP:0040293 Right hemiplegia

Sister Nodes:

Paraplegia/paraparesis (HP:0010551)

Tetraplegia/tetraparesis (HP:0030182)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ABCC6 CL E G H	368	57	ORPHA:758	Pseudoxanthoma elasticum	HP:0040283 - Occasional	415
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ABCD1 CL E G H	215	61	ORPHA:139396	X-linked cerebral adrenoleukodystrophy		135
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ADA2 CL E G H	51816	1839	OMIM:182410	Sneddon syndrome		22
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ADA2 CL E G H	51816	1839	ORPHA:820	Sneddon syndrome		22
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ADA2 CL E G H	51816	1839	OMIM:615688	Vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome		22
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ADAR CL E G H	103	225	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	116
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	AIPL1 CL E G H	23746	359	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	114
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	AKT1 CL E G H	207	391	ORPHA:2495	Meningioma		54
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	AKT3 CL E G H	10000	393	ORPHA:99802	Hemimegalencephaly		19
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	AMACR CL E G H	23600	451	OMIM:614307	Alpha-methylacyl-CoA racemase deficiency		44
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ANGPTL6 CL E G H	83854	23140	ORPHA:231160	Familial cerebral saccular aneurysm
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ARG1 CL E G H	383	663	ORPHA:90	Argininemia	HP:0040282 - Frequent	31
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ARHGAP31 CL E G H	57514	29216	ORPHA:974	Adams-Oliver syndrome		147
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ARNT2 CL E G H	9915	16876	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ARX CL E G H	170302	18060	ORPHA:3175	X-linked spasticity-intellectual disability-epilepsy syndrome		166
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A2 CL E G H	477	800	ORPHA:2131	Alternating hemiplegia of childhood		239
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A2 CL E G H	477	800	OMIM:104290	Alternating hemiplegia of childhood 1		239
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A2 CL E G H	477	800	ORPHA:569	Familial or sporadic hemiplegic migraine		239
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A2 CL E G H	477	800	OMIM:602481	Migraine, familial hemiplegic, 2		239
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A3 CL E G H	478	801	ORPHA:2131	Alternating hemiplegia of childhood		150
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A3 CL E G H	478	801	OMIM:614820	Alternating hemiplegia of childhood 2		150
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP1A3 CL E G H	478	801	OMIM:601338	Cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss		150
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ATP8 CL E G H	4509	7415	ORPHA:480	Kearns-Sayre syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	B3GALNT2 CL E G H	148789	28596	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	43
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	BAP1 CL E G H	8314	950	ORPHA:2495	Meningioma		184
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	BMPR1A CL E G H	657	1076	ORPHA:440437	Familial colorectal cancer Type X	HP:0040283 - Occasional	385
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	C4A CL E G H	720	1323	ORPHA:117	Behçet disease		1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CACNA1A CL E G H	773	1388	ORPHA:2131	Alternating hemiplegia of childhood		449
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CACNA1A CL E G H	773	1388	ORPHA:569	Familial or sporadic hemiplegic migraine		449
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CACNA1A CL E G H	773	1388	ORPHA:97	Familial paroxysmal ataxia		449
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CACNA1A CL E G H	773	1388	OMIM:141500	Migraine, familial hemiplegic, 1		449
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CASZ1 CL E G H	54897	26002	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CBS CL E G H	875	1550	ORPHA:394	Classic homocystinuria	HP:0040283 - Occasional	242
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CCR1 CL E G H	1230	1602	ORPHA:117	Behçet disease
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CEP290 CL E G H	80184	29021	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	342
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CFH CL E G H	3075	4883	OMIM:235400	Hemolytic uremic syndrome, atypical, susceptibility to, 1		86
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CFHR1 CL E G H	3078	4888	OMIM:235400	Hemolytic uremic syndrome, atypical, susceptibility to, 1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CFHR3 CL E G H	10878	16980	OMIM:235400	Hemolytic uremic syndrome, atypical, susceptibility to, 1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COL3A1 CL E G H	1281	2201	ORPHA:231160	Familial cerebral saccular aneurysm		749
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COL4A1 CL E G H	1282	2202	OMIM:175780	Brain small vessel disease 1 with or without ocular anomalies		193
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COL4A2 CL E G H	1284	2203	OMIM:614483	PORENCEPHALY 2; POREN2		147
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COQ2 CL E G H	27235	25223	OMIM:607426	Coenzyme Q10 deficiency, primary, 1		54
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COX1 CL E G H	4512	7419	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COX1 CL E G H	4512	7419	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COX2 CL E G H	4513	7421	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COX2 CL E G H	4513	7421	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COX3 CL E G H	4514	7422	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	COX3 CL E G H	4514	7422	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CPT1A CL E G H	1374	2328	ORPHA:156	Carnitine palmitoyl transferase 1A deficiency	HP:0040282 - Frequent	99
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CRB1 CL E G H	23418	2343	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	156
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CRX CL E G H	1406	2383	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	158
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CTC1 CL E G H	80169	26169	OMIM:612199	Cerebroretinal microangiopathy with calcifications and cysts		160
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CTLA4 CL E G H	1493	2505	ORPHA:900	Granulomatosis with polyangiitis		10
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CYP26C1 CL E G H	340665	20577	ORPHA:398189	Focal facial dermal dysplasia type IV		2
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CYTB CL E G H	4519	7427	ORPHA:137675	Histiocytoid cardiomyopathy
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	CYTB CL E G H	4519	7427	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	DCC CL E G H	1630	2701	OMIM:617542	GAZE PALSY, FAMILIAL HORIZONTAL, WITH PROGRESSIVE SCOLIOSIS, 2; HGPPS2		36
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	DLL4 CL E G H	54567	2910	ORPHA:974	Adams-Oliver syndrome		9
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	DNASE1L3 CL E G H	1776	2959	ORPHA:36412	Hypocomplementemic urticarial vasculitis	HP:0040283 - Occasional	3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	DNM1L CL E G H	10059	2973	ORPHA:98673	Autosomal dominant optic atrophy, classic form		94
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	DOCK6 CL E G H	57572	19189	ORPHA:974	Adams-Oliver syndrome		18
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	DOCK8 CL E G H	81704	19191	OMIM:243700	Hyper-Ige recurrent infection syndrome, autosomal recessive		217
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ENG CL E G H	2022	3349	ORPHA:231160	Familial cerebral saccular aneurysm		186
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ENPP1 CL E G H	5167	3356	ORPHA:758	Pseudoxanthoma elasticum	HP:0040283 - Occasional	151
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	EOGT CL E G H	285203	28526	ORPHA:974	Adams-Oliver syndrome		4
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	EPCAM CL E G H	4072	11529	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	170
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ERAP1 CL E G H	51752	18173	ORPHA:117	Behçet disease		1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	FAN1 CL E G H	22909	29170	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	15
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	FAS CL E G H	355	11920	ORPHA:117	Behçet disease		59
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	FGFR1 CL E G H	2260	3688	ORPHA:2396	Encephalocraniocutaneous lipomatosis		172
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	FGFR1 CL E G H	2260	3688	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent	172
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	FKRP CL E G H	79147	17997	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	157
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	FKTN CL E G H	2218	3622	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	184
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GABRD CL E G H	2563	4084	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	10
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GALC CL E G H	2581	4115	ORPHA:206448	Adult Krabbe disease		160
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GALC CL E G H	2581	4115	ORPHA:206443	Late-infantile/juvenile Krabbe disease		160
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GBE1 CL E G H	2632	4180	ORPHA:206583	Adult polyglucosan body disease		86
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GDF3 CL E G H	9573	4218	ORPHA:2345	Isolated Klippel-Feil syndrome	HP:0040283 - Occasional	7
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GDF6 CL E G H	392255	4221	ORPHA:2345	Isolated Klippel-Feil syndrome	HP:0040283 - Occasional	64
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GDF6 CL E G H	392255	4221	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	64
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GMPPB CL E G H	29925	22932	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	34
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GNAQ CL E G H	2776	4390	ORPHA:624	Familial multiple nevi flammei		7
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GNB1 CL E G H	2782	4396	OMIM:616973	Mental retardation, autosomal dominant 42		12
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GUCY1A1 CL E G H	2982	4685	OMIM:615750	Moyamoya disease 6 with achalasia
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	GUCY2D CL E G H	3000	4689	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	124
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HESX1 CL E G H	8820	4877	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent	21
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HLA-B CL E G H	3106	4932	ORPHA:117	Behçet disease		4
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HLA-DPA1 CL E G H	3113	4938	ORPHA:900	Granulomatosis with polyangiitis
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HLA-DPB1 CL E G H	3115	4940	ORPHA:900	Granulomatosis with polyangiitis		1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HLA-DQB1 CL E G H	3119	4944	OMIM:123400	Creutzfeldt-Jakob disease
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HMGCL CL E G H	3155	5005	ORPHA:20	3-hydroxy-3-methylglutaric aciduria		35
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HPRT1 CL E G H	3251	5157	ORPHA:510	Lesch-Nyhan syndrome	HP:0040281 - Very frequent	76
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HRAS CL E G H	3265	5173	ORPHA:2874	Phakomatosis pigmentokeratotica		113
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HSPG2 CL E G H	3339	5273	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	345
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	HTRA1 CL E G H	5654	9476	ORPHA:199354	Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy		34
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IFIH1 CL E G H	64135	18873	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	28
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IFNGR1 CL E G H	3459	5439	ORPHA:117	Behçet disease		60
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IFT140 CL E G H	9742	29077	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	148
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IKBKG CL E G H	8517	5961	ORPHA:464	Incontinentia pigmenti	HP:0040283 - Occasional	52
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IL10 CL E G H	3586	5962	ORPHA:117	Behçet disease		2
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IL12A CL E G H	3592	5969	ORPHA:117	Behçet disease
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IL12A-AS1 CL E G H	101928376	49094	ORPHA:117	Behçet disease
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IL23R CL E G H	149233	19100	ORPHA:117	Behçet disease		1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IMPDH1 CL E G H	3614	6052	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	52
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IQCB1 CL E G H	9657	28949	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	61
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	IRAK1 CL E G H	3654	6112	ORPHA:93552	Pediatric systemic lupus erythematosus
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	KCNAB2 CL E G H	8514	6229	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	KCNJ13 CL E G H	3769	6259	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	42
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	KLRC4 CL E G H	8302	6377	ORPHA:117	Behçet disease
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	KRAS CL E G H	3845	6407	ORPHA:2396	Encephalocraniocutaneous lipomatosis		196
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	KRAS CL E G H	3845	6407	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	196
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	L1CAM CL E G H	3897	6470	ORPHA:2182	Hydrocephalus with stenosis of the aqueduct of Sylvius	HP:0040281 - Very frequent	134
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	L1CAM CL E G H	3897	6470	ORPHA:2466	MASA syndrome	HP:0040281 - Very frequent	134
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	LAGE3 CL E G H	8270	26058	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	LARGE1 CL E G H	9215	6511	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	136
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	LCA5 CL E G H	167691	31923	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	70
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	LRAT CL E G H	9227	6685	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	62
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	LSM11 CL E G H	134353	30860	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	LUZP1 CL E G H	7798	14985	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MEFV CL E G H	4210	6998	ORPHA:117	Behçet disease		281
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MEOX1 CL E G H	4222	7013	ORPHA:2345	Isolated Klippel-Feil syndrome	HP:0040283 - Occasional	5
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MLH1 CL E G H	4292	7127	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	1819
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MLH3 CL E G H	27030	7128	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	131
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MMP23B CL E G H	8510	7171	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MMUT CL E G H	4594	7526	ORPHA:289916	Vitamin B12-unresponsive methylmalonic acidemia type mut0	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MSH2 CL E G H	4436	7325	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	2162
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MSH6 CL E G H	2956	7329	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	2232
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MTHFR CL E G H	4524	7436	ORPHA:395	Homocystinuria due to methylene tetrahydrofolate reductase deficiency		183
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MTOR CL E G H	2475	3942	OMIM:607341	Focal cortical dysplasia of taylor		68
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	MTOR CL E G H	2475	3942	ORPHA:99802	Hemimegalencephaly		68
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NAGA CL E G H	4668	7631	ORPHA:79279	Alpha-N-acetylgalactosaminidase deficiency type 1	HP:0040282 - Frequent	47
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND1 CL E G H	4535	7455	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND1 CL E G H	4535	7455	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND4 CL E G H	4538	7459	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND5 CL E G H	4540	7461	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND5 CL E G H	4540	7461	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND6 CL E G H	4541	7462	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	ND6 CL E G H	4541	7462	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NF2 CL E G H	4771	7773	ORPHA:2495	Meningioma		220
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NF2 CL E G H	4771	7773	ORPHA:637	Neurofibromatosis type 2		220
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NMNAT1 CL E G H	64802	17877	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	15
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NOTCH1 CL E G H	4851	7881	ORPHA:974	Adams-Oliver syndrome		452
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NOTCH3 CL E G H	4854	7883	OMIM:125310	Cerebral arteriopathy, autosomal dominant, with subcortical infarctsand leukoencephalopathy		144
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NOTCH3 CL E G H	4854	7883	ORPHA:136	Cerebral autosomal dominant arteriopathy-subcortical infarcts-leukoencephalopathy		144
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NOTCH3 CL E G H	4854	7883	ORPHA:2591	Infantile myofibromatosis	HP:0040283 - Occasional	144
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NPPA CL E G H	4878	7939	ORPHA:1344	Atrial standstill		13
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NUP107 CL E G H	57122	29914	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional	5
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	NUP133 CL E G H	55746	18016	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional	1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	OPA1 CL E G H	4976	8140	ORPHA:98673	Autosomal dominant optic atrophy, classic form		214
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	OSGEP CL E G H	55644	18028	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	OTX2 CL E G H	5015	8522	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent	41
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PAH CL E G H	5053	8582	ORPHA:79254	Classic phenylketonuria		641
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PCYT1A CL E G H	5130	8754	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	11
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PDGFB CL E G H	5155	8800	ORPHA:2495	Meningioma		9
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PDGFRB CL E G H	5159	8804	ORPHA:2591	Infantile myofibromatosis	HP:0040283 - Occasional	28
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PDPN CL E G H	10630	29602	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PEX7 CL E G H	5191	8860	ORPHA:773	Refsum disease	HP:0040281 - Very frequent	72
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PHYH CL E G H	5264	8940	ORPHA:773	Refsum disease	HP:0040281 - Very frequent	45
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PIK3CA CL E G H	5290	8975	ORPHA:99802	Hemimegalencephaly		162
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PIK3CA CL E G H	5290	8975	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	162
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PIK3CA CL E G H	5290	8975	ORPHA:2495	Meningioma		162
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PLA2G6 CL E G H	8398	9039	OMIM:612953	Parkinson disease 14, autosomal recessive		133
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PMS1 CL E G H	5378	9121	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	56
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PMS2 CL E G H	5395	9122	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	1121
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PNPLA6 CL E G H	10908	16268	ORPHA:1173	Cerebellar ataxia-hypogonadism syndrome	HP:0040282 - Frequent	103
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PNPLA8 CL E G H	50640	28900	OMIM:251950	Mitochondrial myopathy with lactic acidosis		3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	POMGNT1 CL E G H	55624	19139	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	180
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	POMT1 CL E G H	10585	9202	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	213
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	POMT2 CL E G H	29954	19743	ORPHA:588	Muscle-eye-brain disease	HP:0040283 - Occasional	221
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRDM16 CL E G H	63976	14000	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	148
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRF1 CL E G H	5551	9360	OMIM:603553	Hemophagocytic lymphohistiocytosis, familial, 2		58
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRKCZ CL E G H	5590	9412	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRNP CL E G H	5621	9449	OMIM:123400	Creutzfeldt-Jakob disease		69
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRNP CL E G H	5621	9449	ORPHA:282166	Inherited Creutzfeldt-Jakob disease		69
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PROKR2 CL E G H	128674	15836	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent	34
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRORP CL E G H	9692	19958	OMIM:619737	COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 54; COXPD54
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRRT2 CL E G H	112476	30500	ORPHA:569	Familial or sporadic hemiplegic migraine		94
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PRTN3 CL E G H	5657	9495	ORPHA:900	Granulomatosis with polyangiitis
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PTEN CL E G H	5728	9588	ORPHA:137608	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	HP:0040283 - Occasional	948
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	PTPN22 CL E G H	26191	9652	ORPHA:900	Granulomatosis with polyangiitis		3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RBPJ CL E G H	3516	5724	ORPHA:974	Adams-Oliver syndrome		3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RD3 CL E G H	343035	19689	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	95
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RDH12 CL E G H	145226	19977	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	45
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RERE CL E G H	473	9965	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	16
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RHOBTB2 CL E G H	23221	18756	OMIM:618004	Epileptic encephalopathy, early infantile, 64		1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RNASEH2A CL E G H	10535	18518	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	33
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RNASEH2B CL E G H	79621	25671	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	34
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RNASEH2C CL E G H	84153	24116	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	60
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RNF216 CL E G H	54476	21698	ORPHA:1173	Cerebellar ataxia-hypogonadism syndrome	HP:0040282 - Frequent	10
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RNU7-1 CL E G H	100147744	34033	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RPE65 CL E G H	6121	10294	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	129
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RPGRIP1 CL E G H	57096	13436	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	109
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RPS20 CL E G H	6224	10405	ORPHA:440437	Familial colorectal cancer Type X	HP:0040283 - Occasional	1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	RRM2B CL E G H	50484	17296	ORPHA:480	Kearns-Sayre syndrome	HP:0040283 - Occasional	125
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SAMHD1 CL E G H	25939	15925	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	55
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SCN1A CL E G H	6323	10585	ORPHA:569	Familial or sporadic hemiplegic migraine		1053
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SCN1A CL E G H	6323	10585	OMIM:609634	Migraine, familial hemiplegic, 3		1053
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SCN5A CL E G H	6331	10593	ORPHA:1344	Atrial standstill		1134
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SEMA4A CL E G H	64218	10729	ORPHA:440437	Familial colorectal cancer Type X	HP:0040283 - Occasional	48
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SKI CL E G H	6497	10896	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	150
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SLC12A6 CL E G H	9990	10914	ORPHA:1496	Corpus callosum agenesis-neuronopathy syndrome	HP:0040281 - Very frequent	163
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SLC1A3 CL E G H	6507	10941	ORPHA:2131	Alternating hemiplegia of childhood		63
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SLC1A3 CL E G H	6507	10941	ORPHA:209967	Episodic ataxia type 6		63
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SLC1A3 CL E G H	6507	10941	OMIM:612656	Episodic ataxia, type 6		63
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SLC2A1 CL E G H	6513	11005	ORPHA:71277	Classic glucose transporter type 1 deficiency syndrome		255
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SLC2A1 CL E G H	6513	11005	OMIM:606777	Glut1 deficiency syndrome 1		255
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SMARCAL1 CL E G H	50485	11102	ORPHA:1830	Schimke immuno-osseous dysplasia		74
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SMARCB1 CL E G H	6598	11103	ORPHA:99966	Atypical teratoid rhabdoid tumor	HP:0040282 - Frequent	87
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SMARCB1 CL E G H	6598	11103	ORPHA:2495	Meningioma		87
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SMARCE1 CL E G H	6605	11109	ORPHA:2495	Meningioma		47
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SMO CL E G H	6608	11119	ORPHA:2495	Meningioma		22
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SNORD118 CL E G H	727676	32952	OMIM:614561	Leukoencephalopathy, brain calcifications, and cysts		6
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SOX2 CL E G H	6657	11195	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent	33
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SOX3 CL E G H	6658	11199	ORPHA:3157	Septo-optic dysplasia spectrum	HP:0040282 - Frequent	24
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SP110 CL E G H	3431	5401	ORPHA:79124	Hepatic veno-occlusive disease-immunodeficiency syndrome		49
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SPATA5L1 CL E G H	79029	28762	OMIM:619616	NEURODEVELOPMENTAL DISORDER WITH HEARING LOSS AND SPASTICITY; NEDHLS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SPATA7 CL E G H	55812	20423	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	48
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SPEN CL E G H	23013	17575	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional	4
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SPOP CL E G H	8405	11254	OMIM:618829	NABAIS SA-DE VRIES SYNDROME, TYPE 2; NSDVS2		16
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SPP1 CL E G H	6696	11255	ORPHA:93552	Pediatric systemic lupus erythematosus
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	STAT4 CL E G H	6775	11365	ORPHA:117	Behçet disease		2
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	STAT4 CL E G H	6775	11365	ORPHA:93552	Pediatric systemic lupus erythematosus		2
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SUFU CL E G H	51684	16466	ORPHA:2495	Meningioma		124
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	SUOX CL E G H	6821	11460	OMIM:272300	SULFOCYSTEINURIA		40
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TBC1D24 CL E G H	57465	29203	OMIM:615338	Epileptic encephalopathy, early infantile, 16		271
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TBC1D24 CL E G H	57465	29203	ORPHA:352596	Progressive myoclonic epilepsy with dystonia		271
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TBK1 CL E G H	29110	11584	OMIM:617900	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8		20
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TBX1 CL E G H	6899	11592	OMIM:188400	Digeorge syndrome		32
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TERT CL E G H	7015	11730	ORPHA:2495	Meningioma		238
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TGFBR2 CL E G H	7048	11773	ORPHA:144	Lynch syndrome	HP:0040283 - Occasional	253
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TGFBR3 CL E G H	7049	11774	ORPHA:231160	Familial cerebral saccular aneurysm		1
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	THSD1 CL E G H	55901	17754	ORPHA:231160	Familial cerebral saccular aneurysm		2
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TLR3 CL E G H	7098	11849	OMIM:613002	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 2		3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TLR4 CL E G H	7099	11850	ORPHA:117	Behçet disease		3
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TP53 CL E G H	7157	11998	ORPHA:2807	Papilloma of choroid plexus	HP:0040283 - Occasional	911
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TP53RK CL E G H	112858	16197	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TPP2 CL E G H	7174	12016	ORPHA:444463	Autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TPRKB CL E G H	51002	24259	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRAF7 CL E G H	84231	20456	ORPHA:2495	Meningioma
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TREX1 CL E G H	11277	12269	ORPHA:51	Aicardi-Goutières syndrome	HP:0040282 - Frequent	56
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TREX1 CL E G H	11277	12269	ORPHA:247691	Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations		56
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TREX1 CL E G H	11277	12269	OMIM:192315	Vasculopathy, retinal, with cerebral leukodystrophy		56
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNC CL E G H	4511	7477	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNF CL E G H	4558	7481	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNF CL E G H	4558	7481	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNH CL E G H	4564	7487	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNK CL E G H	4566	7489	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNL1 CL E G H	4567	7490	ORPHA:480	Kearns-Sayre syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNL1 CL E G H	4567	7490	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNL1 CL E G H	4567	7490	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNQ CL E G H	4572	7495	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNQ CL E G H	4572	7495	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNS1 CL E G H	4574	7497	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNS1 CL E G H	4574	7497	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNS2 CL E G H	4575	7498	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNS2 CL E G H	4575	7498	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNV CL E G H	4577	7500	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNW CL E G H	4578	7501	ORPHA:550	MELAS
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TRNW CL E G H	4578	7501	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TSC1 CL E G H	7248	12362	OMIM:607341	Focal cortical dysplasia of taylor		1090
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TSC2 CL E G H	7249	12363	OMIM:607341	Focal cortical dysplasia of taylor		2738
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TTPA CL E G H	7274	12404	ORPHA:96	Ataxia with vitamin E deficiency	HP:0040283 - Occasional	62
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TTR CL E G H	7276	12405	OMIM:105210	Amyloidosis, hereditary, transthyretin-related		107
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TUBB2B CL E G H	347733	30829	OMIM:610031	Cortical dysplasia, complex, with other brain malformations 7		39
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TUBB2B CL E G H	347733	30829	ORPHA:300573	Polymicrogyria due to TUBB2B mutation		39
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TUBB4B CL E G H	10383	20771	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	TULP1 CL E G H	7287	12423	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent	66
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	UBAC2 CL E G H	337867	20486	ORPHA:117	Behçet disease
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	UBE4B CL E G H	10277	12500	ORPHA:1606	1p36 deletion syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	USP45 CL E G H	85015	20080	ORPHA:65	Leber congenital amaurosis	HP:0040282 - Frequent
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	WDR4 CL E G H	10785	12756	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	WDR62 CL E G H	284403	24502	OMIM:604317	Microcephaly 2, primary, autosomal recessive, with or without cortical malformations		224
HP:0004374	HP:0004374	Hemiplegia/hemiparesis	0	WDR73 CL E G H	84942	25928	ORPHA:2065	Galloway-Mowat syndrome	HP:0040283 - Occasional	14
HP:0004374	HP:0001269	Hemiparesis	1	ABCD1 CL E G H	215	61	ORPHA:139396	X-linked cerebral adrenoleukodystrophy	HP:0040283 - Occasional	135
HP:0004374	HP:0001269	Hemiparesis	1	ADA2 CL E G H	51816	1839	ORPHA:820	Sneddon syndrome	HP:0040282 - Frequent	22
HP:0004374	HP:0002301	Hemiplegia	1	ADA2 CL E G H	51816	1839	OMIM:182410	Sneddon syndrome		22
HP:0004374	HP:0002301	Hemiplegia	1	ADA2 CL E G H	51816	1839	OMIM:615688	Vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome		22
HP:0004374	HP:0001269	Hemiparesis	1	AKT1 CL E G H	207	391	ORPHA:2495	Meningioma	HP:0040283 - Occasional	54
HP:0004374	HP:0001269	Hemiparesis	1	AKT3 CL E G H	10000	393	ORPHA:99802	Hemimegalencephaly	HP:0040283 - Occasional	19
HP:0004374	HP:0001269	Hemiparesis	1	AMACR CL E G H	23600	451	OMIM:614307	Alpha-methylacyl-CoA racemase deficiency		44
HP:0004374	HP:0001269	Hemiparesis	1	ANGPTL6 CL E G H	83854	23140	ORPHA:231160	Familial cerebral saccular aneurysm	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	ARHGAP31 CL E G H	57514	29216	ORPHA:974	Adams-Oliver syndrome	HP:0040283 - Occasional	147
HP:0004374	HP:0002301	Hemiplegia	1	ARX CL E G H	170302	18060	ORPHA:3175	X-linked spasticity-intellectual disability-epilepsy syndrome	HP:0040281 - Very frequent	166
HP:0004374	HP:0002301	Hemiplegia	1	ATP1A2 CL E G H	477	800	ORPHA:2131	Alternating hemiplegia of childhood		239
HP:0004374	HP:0002301	Hemiplegia	1	ATP1A2 CL E G H	477	800	OMIM:104290	Alternating hemiplegia of childhood 1		239
HP:0004374	HP:0002301	Hemiplegia	1	ATP1A2 CL E G H	477	800	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040283 - Occasional	239
HP:0004374	HP:0001269	Hemiparesis	1	ATP1A2 CL E G H	477	800	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040282 - Frequent	239
HP:0004374	HP:0002301	Hemiplegia	1	ATP1A2 CL E G H	477	800	OMIM:602481	Migraine, familial hemiplegic, 2	.	239
HP:0004374	HP:0001269	Hemiparesis	1	ATP1A2 CL E G H	477	800	OMIM:602481	Migraine, familial hemiplegic, 2	.	239
HP:0004374	HP:0002301	Hemiplegia	1	ATP1A3 CL E G H	478	801	ORPHA:2131	Alternating hemiplegia of childhood		150
HP:0004374	HP:0002301	Hemiplegia	1	ATP1A3 CL E G H	478	801	OMIM:614820	Alternating hemiplegia of childhood 2	.	150
HP:0004374	HP:0001269	Hemiparesis	1	ATP1A3 CL E G H	478	801	OMIM:601338	Cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss	.	150
HP:0004374	HP:0001269	Hemiparesis	1	BAP1 CL E G H	8314	950	ORPHA:2495	Meningioma	HP:0040283 - Occasional	184
HP:0004374	HP:0001269	Hemiparesis	1	C4A CL E G H	720	1323	ORPHA:117	Behçet disease	HP:0040282 - Frequent	1
HP:0004374	HP:0002301	Hemiplegia	1	CACNA1A CL E G H	773	1388	ORPHA:2131	Alternating hemiplegia of childhood		449
HP:0004374	HP:0001269	Hemiparesis	1	CACNA1A CL E G H	773	1388	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040282 - Frequent	449
HP:0004374	HP:0002301	Hemiplegia	1	CACNA1A CL E G H	773	1388	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040283 - Occasional	449
HP:0004374	HP:0002301	Hemiplegia	1	CACNA1A CL E G H	773	1388	ORPHA:97	Familial paroxysmal ataxia	HP:0040282 - Frequent	449
HP:0004374	HP:0002301	Hemiplegia	1	CACNA1A CL E G H	773	1388	OMIM:141500	Migraine, familial hemiplegic, 1	.	449
HP:0004374	HP:0001269	Hemiparesis	1	CACNA1A CL E G H	773	1388	OMIM:141500	Migraine, familial hemiplegic, 1	.	449
HP:0004374	HP:0001269	Hemiparesis	1	CCR1 CL E G H	1230	1602	ORPHA:117	Behçet disease	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	CFH CL E G H	3075	4883	OMIM:235400	Hemolytic uremic syndrome, atypical, susceptibility to, 1	.	86
HP:0004374	HP:0001269	Hemiparesis	1	CFHR1 CL E G H	3078	4888	OMIM:235400	Hemolytic uremic syndrome, atypical, susceptibility to, 1	.
HP:0004374	HP:0001269	Hemiparesis	1	CFHR3 CL E G H	10878	16980	OMIM:235400	Hemolytic uremic syndrome, atypical, susceptibility to, 1	.
HP:0004374	HP:0001269	Hemiparesis	1	COL3A1 CL E G H	1281	2201	ORPHA:231160	Familial cerebral saccular aneurysm	HP:0040282 - Frequent	749
HP:0004374	HP:0001269	Hemiparesis	1	COL4A1 CL E G H	1282	2202	OMIM:175780	Brain small vessel disease 1 with or without ocular anomalies	.	193
HP:0004374	HP:0002301	Hemiplegia	1	COL4A1 CL E G H	1282	2202	OMIM:175780	Brain small vessel disease 1 with or without ocular anomalies	.	193
HP:0004374	HP:0002301	Hemiplegia	1	COL4A2 CL E G H	1284	2203	OMIM:614483	PORENCEPHALY 2; POREN2		147
HP:0004374	HP:0002301	Hemiplegia	1	COQ2 CL E G H	27235	25223	OMIM:607426	Coenzyme Q10 deficiency, primary, 1		54
HP:0004374	HP:0001269	Hemiparesis	1	COX1 CL E G H	4512	7419	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	COX1 CL E G H	4512	7419	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	COX2 CL E G H	4513	7421	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	COX2 CL E G H	4513	7421	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	COX3 CL E G H	4514	7422	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	COX3 CL E G H	4514	7422	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0002301	Hemiplegia	1	CTC1 CL E G H	80169	26169	OMIM:612199	Cerebroretinal microangiopathy with calcifications and cysts	.	160
HP:0004374	HP:0002301	Hemiplegia	1	CTLA4 CL E G H	1493	2505	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional	10
HP:0004374	HP:0001269	Hemiparesis	1	CYP26C1 CL E G H	340665	20577	ORPHA:398189	Focal facial dermal dysplasia type IV	HP:0040282 - Frequent	2
HP:0004374	HP:0002301	Hemiplegia	1	CYTB CL E G H	4519	7427	ORPHA:137675	Histiocytoid cardiomyopathy	HP:0040284 - Very rare
HP:0004374	HP:0001269	Hemiparesis	1	CYTB CL E G H	4519	7427	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	DCC CL E G H	1630	2701	OMIM:617542	GAZE PALSY, FAMILIAL HORIZONTAL, WITH PROGRESSIVE SCOLIOSIS, 2; HGPPS2		36
HP:0004374	HP:0001269	Hemiparesis	1	DLL4 CL E G H	54567	2910	ORPHA:974	Adams-Oliver syndrome	HP:0040283 - Occasional	9
HP:0004374	HP:0001269	Hemiparesis	1	DNM1L CL E G H	10059	2973	ORPHA:98673	Autosomal dominant optic atrophy, classic form	HP:0040284 - Very rare	94
HP:0004374	HP:0001269	Hemiparesis	1	DOCK6 CL E G H	57572	19189	ORPHA:974	Adams-Oliver syndrome	HP:0040283 - Occasional	18
HP:0004374	HP:0002301	Hemiplegia	1	DOCK8 CL E G H	81704	19191	OMIM:243700	Hyper-Ige recurrent infection syndrome, autosomal recessive	.	217
HP:0004374	HP:0001269	Hemiparesis	1	ENG CL E G H	2022	3349	ORPHA:231160	Familial cerebral saccular aneurysm	HP:0040282 - Frequent	186
HP:0004374	HP:0001269	Hemiparesis	1	EOGT CL E G H	285203	28526	ORPHA:974	Adams-Oliver syndrome	HP:0040283 - Occasional	4
HP:0004374	HP:0001269	Hemiparesis	1	ERAP1 CL E G H	51752	18173	ORPHA:117	Behçet disease	HP:0040282 - Frequent	1
HP:0004374	HP:0001269	Hemiparesis	1	FAS CL E G H	355	11920	ORPHA:117	Behçet disease	HP:0040282 - Frequent	59
HP:0004374	HP:0001269	Hemiparesis	1	FGFR1 CL E G H	2260	3688	ORPHA:2396	Encephalocraniocutaneous lipomatosis	HP:0040283 - Occasional	172
HP:0004374	HP:0002301	Hemiplegia	1	FGFR1 CL E G H	2260	3688	ORPHA:2396	Encephalocraniocutaneous lipomatosis	HP:0040283 - Occasional	172
HP:0004374	HP:0002301	Hemiplegia	1	GALC CL E G H	2581	4115	ORPHA:206448	Adult Krabbe disease	HP:0040284 - Very rare	160
HP:0004374	HP:0002301	Hemiplegia	1	GALC CL E G H	2581	4115	ORPHA:206443	Late-infantile/juvenile Krabbe disease	HP:0040283 - Occasional	160
HP:0004374	HP:0001269	Hemiparesis	1	GBE1 CL E G H	2632	4180	ORPHA:206583	Adult polyglucosan body disease	HP:0040281 - Very frequent	86
HP:0004374	HP:0002301	Hemiplegia	1	GNAQ CL E G H	2776	4390	ORPHA:624	Familial multiple nevi flammei	HP:0040283 - Occasional	7
HP:0004374	HP:0001269	Hemiparesis	1	GNAQ CL E G H	2776	4390	ORPHA:624	Familial multiple nevi flammei	HP:0040283 - Occasional	7
HP:0004374	HP:0002301	Hemiplegia	1	GNB1 CL E G H	2782	4396	OMIM:616973	Mental retardation, autosomal dominant 42		12
HP:0004374	HP:0001269	Hemiparesis	1	GUCY1A1 CL E G H	2982	4685	OMIM:615750	Moyamoya disease 6 with achalasia	HP:0040283 - Occasional
HP:0004374	HP:0001269	Hemiparesis	1	HLA-B CL E G H	3106	4932	ORPHA:117	Behçet disease	HP:0040282 - Frequent	4
HP:0004374	HP:0002301	Hemiplegia	1	HLA-DPA1 CL E G H	3113	4938	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional
HP:0004374	HP:0002301	Hemiplegia	1	HLA-DPB1 CL E G H	3115	4940	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional	1
HP:0004374	HP:0001269	Hemiparesis	1	HLA-DQB1 CL E G H	3119	4944	OMIM:123400	Creutzfeldt-Jakob disease	.
HP:0004374	HP:0001269	Hemiparesis	1	HMGCL CL E G H	3155	5005	ORPHA:20	3-hydroxy-3-methylglutaric aciduria		35
HP:0004374	HP:0001269	Hemiparesis	1	HRAS CL E G H	3265	5173	ORPHA:2874	Phakomatosis pigmentokeratotica		113
HP:0004374	HP:0001269	Hemiparesis	1	HTRA1 CL E G H	5654	9476	ORPHA:199354	Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy		34
HP:0004374	HP:0001269	Hemiparesis	1	IFNGR1 CL E G H	3459	5439	ORPHA:117	Behçet disease	HP:0040282 - Frequent	60
HP:0004374	HP:0001269	Hemiparesis	1	IL10 CL E G H	3586	5962	ORPHA:117	Behçet disease	HP:0040282 - Frequent	2
HP:0004374	HP:0001269	Hemiparesis	1	IL12A CL E G H	3592	5969	ORPHA:117	Behçet disease	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	IL12A-AS1 CL E G H	101928376	49094	ORPHA:117	Behçet disease	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	IL23R CL E G H	149233	19100	ORPHA:117	Behçet disease	HP:0040282 - Frequent	1
HP:0004374	HP:0002301	Hemiplegia	1	IRAK1 CL E G H	3654	6112	ORPHA:93552	Pediatric systemic lupus erythematosus	HP:0040283 - Occasional
HP:0004374	HP:0001269	Hemiparesis	1	KLRC4 CL E G H	8302	6377	ORPHA:117	Behçet disease	HP:0040282 - Frequent
HP:0004374	HP:0002301	Hemiplegia	1	KRAS CL E G H	3845	6407	ORPHA:2396	Encephalocraniocutaneous lipomatosis	HP:0040283 - Occasional	196
HP:0004374	HP:0001269	Hemiparesis	1	KRAS CL E G H	3845	6407	ORPHA:2396	Encephalocraniocutaneous lipomatosis	HP:0040283 - Occasional	196
HP:0004374	HP:0001269	Hemiparesis	1	MEFV CL E G H	4210	6998	ORPHA:117	Behçet disease	HP:0040282 - Frequent	281
HP:0004374	HP:0001269	Hemiparesis	1	MTHFR CL E G H	4524	7436	ORPHA:395	Homocystinuria due to methylene tetrahydrofolate reductase deficiency	HP:0040283 - Occasional	183
HP:0004374	HP:0001269	Hemiparesis	1	MTOR CL E G H	2475	3942	OMIM:607341	Focal cortical dysplasia of taylor	.	68
HP:0004374	HP:0001269	Hemiparesis	1	MTOR CL E G H	2475	3942	ORPHA:99802	Hemimegalencephaly	HP:0040283 - Occasional	68
HP:0004374	HP:0001269	Hemiparesis	1	ND1 CL E G H	4535	7455	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	ND1 CL E G H	4535	7455	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	ND4 CL E G H	4538	7459	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	ND5 CL E G H	4540	7461	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	ND5 CL E G H	4540	7461	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	ND6 CL E G H	4541	7462	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	ND6 CL E G H	4541	7462	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	NF2 CL E G H	4771	7773	ORPHA:2495	Meningioma	HP:0040283 - Occasional	220
HP:0004374	HP:0001269	Hemiparesis	1	NF2 CL E G H	4771	7773	ORPHA:637	Neurofibromatosis type 2	HP:0040283 - Occasional	220
HP:0004374	HP:0001269	Hemiparesis	1	NOTCH1 CL E G H	4851	7881	ORPHA:974	Adams-Oliver syndrome	HP:0040283 - Occasional	452
HP:0004374	HP:0001269	Hemiparesis	1	NOTCH3 CL E G H	4854	7883	OMIM:125310	Cerebral arteriopathy, autosomal dominant, with subcortical infarctsand leukoencephalopathy		144
HP:0004374	HP:0002301	Hemiplegia	1	NOTCH3 CL E G H	4854	7883	ORPHA:136	Cerebral autosomal dominant arteriopathy-subcortical infarcts-leukoencephalopathy	HP:0040283 - Occasional	144
HP:0004374	HP:0002301	Hemiplegia	1	NPPA CL E G H	4878	7939	ORPHA:1344	Atrial standstill	HP:0040283 - Occasional	13
HP:0004374	HP:0001269	Hemiparesis	1	OPA1 CL E G H	4976	8140	ORPHA:98673	Autosomal dominant optic atrophy, classic form	HP:0040284 - Very rare	214
HP:0004374	HP:0002301	Hemiplegia	1	PAH CL E G H	5053	8582	ORPHA:79254	Classic phenylketonuria	HP:0040283 - Occasional	641
HP:0004374	HP:0001269	Hemiparesis	1	PDGFB CL E G H	5155	8800	ORPHA:2495	Meningioma	HP:0040283 - Occasional	9
HP:0004374	HP:0001269	Hemiparesis	1	PIK3CA CL E G H	5290	8975	ORPHA:99802	Hemimegalencephaly	HP:0040283 - Occasional	162
HP:0004374	HP:0001269	Hemiparesis	1	PIK3CA CL E G H	5290	8975	ORPHA:2495	Meningioma	HP:0040283 - Occasional	162
HP:0004374	HP:0001269	Hemiparesis	1	PLA2G6 CL E G H	8398	9039	OMIM:612953	Parkinson disease 14, autosomal recessive		133
HP:0004374	HP:0001269	Hemiparesis	1	PNPLA8 CL E G H	50640	28900	OMIM:251950	Mitochondrial myopathy with lactic acidosis	.	3
HP:0004374	HP:0002301	Hemiplegia	1	PRF1 CL E G H	5551	9360	OMIM:603553	Hemophagocytic lymphohistiocytosis, familial, 2	.	58
HP:0004374	HP:0001269	Hemiparesis	1	PRNP CL E G H	5621	9449	OMIM:123400	Creutzfeldt-Jakob disease	.	69
HP:0004374	HP:0001269	Hemiparesis	1	PRNP CL E G H	5621	9449	ORPHA:282166	Inherited Creutzfeldt-Jakob disease		69
HP:0004374	HP:0001269	Hemiparesis	1	PRORP CL E G H	9692	19958	OMIM:619737	COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 54; COXPD54
HP:0004374	HP:0001269	Hemiparesis	1	PRRT2 CL E G H	112476	30500	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040282 - Frequent	94
HP:0004374	HP:0002301	Hemiplegia	1	PRRT2 CL E G H	112476	30500	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040283 - Occasional	94
HP:0004374	HP:0002301	Hemiplegia	1	PRTN3 CL E G H	5657	9495	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional
HP:0004374	HP:0002301	Hemiplegia	1	PTPN22 CL E G H	26191	9652	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional	3
HP:0004374	HP:0001269	Hemiparesis	1	RBPJ CL E G H	3516	5724	ORPHA:974	Adams-Oliver syndrome	HP:0040283 - Occasional	3
HP:0004374	HP:0001269	Hemiparesis	1	RHOBTB2 CL E G H	23221	18756	OMIM:618004	Epileptic encephalopathy, early infantile, 64	.	1
HP:0004374	HP:0001269	Hemiparesis	1	SCN1A CL E G H	6323	10585	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040282 - Frequent	1053
HP:0004374	HP:0002301	Hemiplegia	1	SCN1A CL E G H	6323	10585	ORPHA:569	Familial or sporadic hemiplegic migraine	HP:0040283 - Occasional	1053
HP:0004374	HP:0001269	Hemiparesis	1	SCN1A CL E G H	6323	10585	OMIM:609634	Migraine, familial hemiplegic, 3	.	1053
HP:0004374	HP:0002301	Hemiplegia	1	SCN1A CL E G H	6323	10585	OMIM:609634	Migraine, familial hemiplegic, 3	.	1053
HP:0004374	HP:0002301	Hemiplegia	1	SCN5A CL E G H	6331	10593	ORPHA:1344	Atrial standstill	HP:0040283 - Occasional	1134
HP:0004374	HP:0002301	Hemiplegia	1	SLC1A3 CL E G H	6507	10941	ORPHA:2131	Alternating hemiplegia of childhood		63
HP:0004374	HP:0002301	Hemiplegia	1	SLC1A3 CL E G H	6507	10941	ORPHA:209967	Episodic ataxia type 6	HP:0040283 - Occasional	63
HP:0004374	HP:0002301	Hemiplegia	1	SLC1A3 CL E G H	6507	10941	OMIM:612656	Episodic ataxia, type 6	.	63
HP:0004374	HP:0001269	Hemiparesis	1	SLC1A3 CL E G H	6507	10941	OMIM:612656	Episodic ataxia, type 6	.	63
HP:0004374	HP:0001269	Hemiparesis	1	SLC2A1 CL E G H	6513	11005	ORPHA:71277	Classic glucose transporter type 1 deficiency syndrome	HP:0040282 - Frequent	255
HP:0004374	HP:0001269	Hemiparesis	1	SLC2A1 CL E G H	6513	11005	OMIM:606777	Glut1 deficiency syndrome 1	.	255
HP:0004374	HP:0002301	Hemiplegia	1	SMARCAL1 CL E G H	50485	11102	ORPHA:1830	Schimke immuno-osseous dysplasia	HP:0040283 - Occasional	74
HP:0004374	HP:0001269	Hemiparesis	1	SMARCAL1 CL E G H	50485	11102	ORPHA:1830	Schimke immuno-osseous dysplasia	HP:0040283 - Occasional	74
HP:0004374	HP:0001269	Hemiparesis	1	SMARCB1 CL E G H	6598	11103	ORPHA:2495	Meningioma	HP:0040283 - Occasional	87
HP:0004374	HP:0001269	Hemiparesis	1	SMARCE1 CL E G H	6605	11109	ORPHA:2495	Meningioma	HP:0040283 - Occasional	47
HP:0004374	HP:0001269	Hemiparesis	1	SMO CL E G H	6608	11119	ORPHA:2495	Meningioma	HP:0040283 - Occasional	22
HP:0004374	HP:0002301	Hemiplegia	1	SNORD118 CL E G H	727676	32952	OMIM:614561	Leukoencephalopathy, brain calcifications, and cysts	.	6
HP:0004374	HP:0001269	Hemiparesis	1	SP110 CL E G H	3431	5401	ORPHA:79124	Hepatic veno-occlusive disease-immunodeficiency syndrome	HP:0040283 - Occasional	49
HP:0004374	HP:0001269	Hemiparesis	1	SPATA5L1 CL E G H	79029	28762	OMIM:619616	NEURODEVELOPMENTAL DISORDER WITH HEARING LOSS AND SPASTICITY; NEDHLS
HP:0004374	HP:0001269	Hemiparesis	1	SPOP CL E G H	8405	11254	OMIM:618829	NABAIS SA-DE VRIES SYNDROME, TYPE 2; NSDVS2		16
HP:0004374	HP:0002301	Hemiplegia	1	SPP1 CL E G H	6696	11255	ORPHA:93552	Pediatric systemic lupus erythematosus	HP:0040283 - Occasional
HP:0004374	HP:0001269	Hemiparesis	1	STAT4 CL E G H	6775	11365	ORPHA:117	Behçet disease	HP:0040282 - Frequent	2
HP:0004374	HP:0002301	Hemiplegia	1	STAT4 CL E G H	6775	11365	ORPHA:93552	Pediatric systemic lupus erythematosus	HP:0040283 - Occasional	2
HP:0004374	HP:0001269	Hemiparesis	1	SUFU CL E G H	51684	16466	ORPHA:2495	Meningioma	HP:0040283 - Occasional	124
HP:0004374	HP:0002301	Hemiplegia	1	SUOX CL E G H	6821	11460	OMIM:272300	SULFOCYSTEINURIA	.	40
HP:0004374	HP:0001269	Hemiparesis	1	TBC1D24 CL E G H	57465	29203	OMIM:615338	Epileptic encephalopathy, early infantile, 16	.	271
HP:0004374	HP:0002301	Hemiplegia	1	TBC1D24 CL E G H	57465	29203	ORPHA:352596	Progressive myoclonic epilepsy with dystonia	HP:0040283 - Occasional	271
HP:0004374	HP:0001269	Hemiparesis	1	TBC1D24 CL E G H	57465	29203	ORPHA:352596	Progressive myoclonic epilepsy with dystonia	HP:0040283 - Occasional	271
HP:0004374	HP:0001269	Hemiparesis	1	TBK1 CL E G H	29110	11584	OMIM:617900	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8	.	20
HP:0004374	HP:0001269	Hemiparesis	1	TBX1 CL E G H	6899	11592	OMIM:188400	Digeorge syndrome		32
HP:0004374	HP:0001269	Hemiparesis	1	TERT CL E G H	7015	11730	ORPHA:2495	Meningioma	HP:0040283 - Occasional	238
HP:0004374	HP:0001269	Hemiparesis	1	TGFBR3 CL E G H	7049	11774	ORPHA:231160	Familial cerebral saccular aneurysm	HP:0040282 - Frequent	1
HP:0004374	HP:0001269	Hemiparesis	1	THSD1 CL E G H	55901	17754	ORPHA:231160	Familial cerebral saccular aneurysm	HP:0040282 - Frequent	2
HP:0004374	HP:0001269	Hemiparesis	1	TLR3 CL E G H	7098	11849	OMIM:613002	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 2	HP:0040284 - Very rare	3
HP:0004374	HP:0001269	Hemiparesis	1	TLR4 CL E G H	7099	11850	ORPHA:117	Behçet disease	HP:0040282 - Frequent	3
HP:0004374	HP:0001269	Hemiparesis	1	TPP2 CL E G H	7174	12016	ORPHA:444463	Autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRAF7 CL E G H	84231	20456	ORPHA:2495	Meningioma	HP:0040283 - Occasional
HP:0004374	HP:0001269	Hemiparesis	1	TREX1 CL E G H	11277	12269	ORPHA:247691	Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	HP:0040283 - Occasional	56
HP:0004374	HP:0001269	Hemiparesis	1	TREX1 CL E G H	11277	12269	OMIM:192315	Vasculopathy, retinal, with cerebral leukodystrophy	.	56
HP:0004374	HP:0001269	Hemiparesis	1	TRNC CL E G H	4511	7477	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNF CL E G H	4558	7481	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNF CL E G H	4558	7481	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNH CL E G H	4564	7487	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNK CL E G H	4566	7489	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNL1 CL E G H	4567	7490	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNL1 CL E G H	4567	7490	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNQ CL E G H	4572	7495	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNQ CL E G H	4572	7495	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNS1 CL E G H	4574	7497	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNS1 CL E G H	4574	7497	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNS2 CL E G H	4575	7498	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNS2 CL E G H	4575	7498	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNV CL E G H	4577	7500	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TRNW CL E G H	4578	7501	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	TRNW CL E G H	4578	7501	OMIM:540000	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	.
HP:0004374	HP:0001269	Hemiparesis	1	TSC1 CL E G H	7248	12362	OMIM:607341	Focal cortical dysplasia of taylor	.	1090
HP:0004374	HP:0001269	Hemiparesis	1	TSC2 CL E G H	7249	12363	OMIM:607341	Focal cortical dysplasia of taylor	.	2738
HP:0004374	HP:0001269	Hemiparesis	1	TTR CL E G H	7276	12405	OMIM:105210	Amyloidosis, hereditary, transthyretin-related	.	107
HP:0004374	HP:0001269	Hemiparesis	1	TUBB2B CL E G H	347733	30829	OMIM:610031	Cortical dysplasia, complex, with other brain malformations 7	.	39
HP:0004374	HP:0001269	Hemiparesis	1	TUBB2B CL E G H	347733	30829	ORPHA:300573	Polymicrogyria due to TUBB2B mutation	HP:0040282 - Frequent	39
HP:0004374	HP:0001269	Hemiparesis	1	UBAC2 CL E G H	337867	20486	ORPHA:117	Behçet disease	HP:0040282 - Frequent
HP:0004374	HP:0001269	Hemiparesis	1	WDR62 CL E G H	284403	24502	OMIM:604317	Microcephaly 2, primary, autosomal recessive, with or without cortical malformations	.	224
HP:0004374	HP:0040292	Left hemiplegia	2	CL E G H
HP:0004374	HP:0012194	Episodic hemiplegia	2	ATP1A2 CL E G H	477	800	ORPHA:2131	Alternating hemiplegia of childhood	HP:0040281 - Very frequent	239
HP:0004374	HP:0012194	Episodic hemiplegia	2	ATP1A2 CL E G H	477	800	OMIM:104290	Alternating hemiplegia of childhood 1	.	239
HP:0004374	HP:0012194	Episodic hemiplegia	2	ATP1A3 CL E G H	478	801	ORPHA:2131	Alternating hemiplegia of childhood	HP:0040281 - Very frequent	150
HP:0004374	HP:0012194	Episodic hemiplegia	2	CACNA1A CL E G H	773	1388	ORPHA:2131	Alternating hemiplegia of childhood	HP:0040281 - Very frequent	449
HP:0004374	HP:0040293	Right hemiplegia	2	COQ2 CL E G H	27235	25223	OMIM:607426	Coenzyme Q10 deficiency, primary, 1		54
HP:0004374	HP:0011099	Spastic hemiparesis	2	HMGCL CL E G H	3155	5005	ORPHA:20	3-hydroxy-3-methylglutaric aciduria	HP:0040284 - Very rare	35
HP:0004374	HP:0011099	Spastic hemiparesis	2	PRNP CL E G H	5621	9449	ORPHA:282166	Inherited Creutzfeldt-Jakob disease	HP:0040282 - Frequent	69
HP:0004374	HP:0012194	Episodic hemiplegia	2	SLC1A3 CL E G H	6507	10941	ORPHA:2131	Alternating hemiplegia of childhood	HP:0040281 - Very frequent	63
HP:0004374	HP:0011099	Spastic hemiparesis	2	SPATA5L1 CL E G H	79029	28762	OMIM:619616	NEURODEVELOPMENTAL DISORDER WITH HEARING LOSS AND SPASTICITY; NEDHLS

Genes (227) :ABCC6 ABCD1 ADA2 ADAR AIPL1 AKT1 AKT3 AMACR ANGPTL6 ARG1 ARHGAP31 ARNT2 ARX ATP1A2 ATP1A3 ATP8 B3GALNT2 BAP1 BMPR1A C4A CACNA1A CASZ1 CBS CCR1 CEP290 CFH CFHR1 CFHR3 COL3A1 COL4A1 COL4A2 COQ2 COX1 COX2 COX3 CPT1A CRB1 CRX CTC1 CTLA4 CYP26C1 CYTB DCC DLL4 DNASE1L3 DNM1L DOCK6 DOCK8 ENG ENPP1 EOGT EPCAM ERAP1 FAN1 FAS FGFR1 FKRP FKTN GABRD GALC GBE1 GDF3 GDF6 GMPPB GNAQ GNB1 GUCY1A1 GUCY2D HESX1 HLA-B HLA-DPA1 HLA-DPB1 HLA-DQB1 HMGCL HPRT1 HRAS HSPG2 HTRA1 IFIH1 IFNGR1 IFT140 IKBKG IL10 IL12A IL12A-AS1 IL23R IMPDH1 IQCB1 IRAK1 KCNAB2 KCNJ13 KLRC4 KRAS L1CAM LAGE3 LARGE1 LCA5 LRAT LSM11 LUZP1 MEFV MEOX1 MLH1 MLH3 MMP23B MMUT MSH2 MSH6 MTHFR MTOR NAGA ND1 ND4 ND5 ND6 NF2 NMNAT1 NOTCH1 NOTCH3 NPPA NUP107 NUP133 OPA1 OSGEP OTX2 PAH PCYT1A PDGFB PDGFRB PDPN PEX7 PHYH PIK3CA PLA2G6 PMS1 PMS2 PNPLA6 PNPLA8 POMGNT1 POMT1 POMT2 PRDM16 PRF1 PRKCZ PRNP PROKR2 PRORP PRRT2 PRTN3 PTEN PTPN22 RBPJ RD3 RDH12 RERE RHOBTB2 RNASEH2A RNASEH2B RNASEH2C RNF216 RNU7-1 RPE65 RPGRIP1 RPS20 RRM2B SAMHD1 SCN1A SCN5A SEMA4A SKI SLC12A6 SLC1A3 SLC2A1 SMARCAL1 SMARCB1 SMARCE1 SMO SNORD118 SOX2 SOX3 SP110 SPATA5L1 SPATA7 SPEN SPOP SPP1 STAT4 SUFU SUOX TBC1D24 TBK1 TBX1 TERT TGFBR2 TGFBR3 THSD1 TLR3 TLR4 TP53 TP53RK TPP2 TPRKB TRAF7 TREX1 TRNC TRNF TRNH TRNK TRNL1 TRNQ TRNS1 TRNS2 TRNV TRNW TSC1 TSC2 TTPA TTR TUBB2B TUBB4B TULP1 UBAC2 UBE4B USP45 WDR4 WDR62 WDR73

Diseases (109) :ORPHA:758 ORPHA:139396 OMIM:182410 ORPHA:820 OMIM:615688 ORPHA:51 ORPHA:65 ORPHA:2495 ORPHA:99802 OMIM:614307 ORPHA:231160 ORPHA:90 ORPHA:974 ORPHA:3157 ORPHA:3175 ORPHA:2131 OMIM:104290 ORPHA:569 OMIM:602481 OMIM:614820 OMIM:601338 ORPHA:480 ORPHA:588 ORPHA:440437 ORPHA:117 ORPHA:97 OMIM:141500 ORPHA:1606 ORPHA:394 OMIM:235400 OMIM:175780 OMIM:614483 OMIM:607426 ORPHA:550 OMIM:540000 ORPHA:156 OMIM:612199 ORPHA:900 ORPHA:398189 ORPHA:137675 OMIM:617542 ORPHA:36412 ORPHA:98673 OMIM:243700 ORPHA:144 ORPHA:2396 ORPHA:206448 ORPHA:206443 ORPHA:206583 ORPHA:2345 ORPHA:624 OMIM:616973 OMIM:615750 OMIM:123400 ORPHA:20 ORPHA:510 ORPHA:2874 ORPHA:199354 ORPHA:464 ORPHA:93552 ORPHA:2182 ORPHA:2466 ORPHA:2065 ORPHA:289916 ORPHA:395 OMIM:607341 ORPHA:79279 ORPHA:637 OMIM:125310 ORPHA:136 ORPHA:2591 ORPHA:1344 ORPHA:79254 ORPHA:773 OMIM:612953 ORPHA:1173 OMIM:251950 OMIM:603553 ORPHA:282166 OMIM:619737 ORPHA:137608 OMIM:618004 OMIM:609634 ORPHA:1496 ORPHA:209967 OMIM:612656 ORPHA:71277 OMIM:606777 ORPHA:1830 ORPHA:99966 OMIM:614561 ORPHA:79124 OMIM:619616 OMIM:618829 OMIM:272300 OMIM:615338 ORPHA:352596 OMIM:617900 OMIM:188400 OMIM:613002 ORPHA:2807 ORPHA:444463 ORPHA:247691 OMIM:192315 ORPHA:96 OMIM:105210 OMIM:610031 ORPHA:300573 OMIM:604317

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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