Human Phenotype Ontology 
Grandparent Node:
expand
Clinical course (HP:0031797)help
Parent Node:
expand
Temporal pattern (HP:0011008)help
..Starting node
..expand
Insidious onset (HP:0003587)help
Term ID: 3587
Name: Insidious onset
Synonym: Gradual onset
Definition: Gradual, very slow onset of disease manifestations.
Comments:
Reference: HP:0003587
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAcute (HP:0011009) help
..expandChronic (HP:0011010) help
..expandDiurnal (HP:0025302) help
..expandMigratory (HP:0025279) help
..expandNocturnal (HP:0025301) help
..expandProlonged (HP:0025297) help
..expandRecurrent (HP:0031796) help
..expandSubacute (HP:0011011) help
..expandTransient (HP:0025153) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0003587HP:0003587Insidious onset0ADH1C CL E G H126251OMIM:168600Parkinson disease, late-onset.4
HP:0003587HP:0003587Insidious onset0ATL1 CL E G H5106211231OMIM:182600Spastic paraplegia 3, autosomal dominant.71
HP:0003587HP:0003587Insidious onset0ATXN2 CL E G H631110555OMIM:168600Parkinson disease, late-onset.11
HP:0003587HP:0003587Insidious onset0ATXN8OS CL E G H631510561OMIM:168600Parkinson disease, late-onset.1
HP:0003587HP:0003587Insidious onset0EIF4G1 CL E G H19813296OMIM:614251Parkinson disease 18.2
HP:0003587HP:0003587Insidious onset0GBA1 CL E G H26294177OMIM:168600Parkinson disease, late-onset.
HP:0003587HP:0003587Insidious onset0GLUD2 CL E G H27474336OMIM:168600Parkinson disease, late-onset.1
HP:0003587HP:0003587Insidious onset0MAPT CL E G H41376893OMIM:168600Parkinson disease, late-onset.140
HP:0003587HP:0003587Insidious onset0MPZ CL E G H43597225OMIM:118200Charcot-Marie-Tooth disease, demyelinating, type 1B.134
HP:0003587HP:0003587Insidious onset0NIPA1 CL E G H12360617043OMIM:600363Spastic paraplegia 6, autosomal dominant.117
HP:0003587HP:0003587Insidious onset0NR4A2 CL E G H49297981OMIM:168600Parkinson disease, late-onset.27
HP:0003587HP:0003587Insidious onset0OPA1 CL E G H49768140OMIM:165500Optic atrophy 1.214
HP:0003587HP:0003587Insidious onset0PMP22 CL E G H53769118OMIM:118220Charcot-Marie-Tooth disease, demyelinating, type 1A.79
HP:0003587HP:0003587Insidious onset0SNCA CL E G H662211138OMIM:168601Parkinson disease 1, autosomal dominant.65
HP:0003587HP:0003587Insidious onset0SNCAIP CL E G H962711139OMIM:168600Parkinson disease, late-onset.35
HP:0003587HP:0003587Insidious onset0SPAST CL E G H668311233OMIM:182601Spastic paraplegia 4, autosomal dominant.208
HP:0003587HP:0003587Insidious onset0TBP CL E G H690811588OMIM:168600Parkinson disease, late-onset.7
HP:0003587HP:0003587Insidious onset0TRNT CL E G H45767499OMIM:168600Parkinson disease, late-onset.
HP:0003587HP:0003587Insidious onset0WASHC5 CL E G H989728984OMIM:603563Spastic paraplegia 8, autosomal dominant.83


Genes (19) :ADH1C ATL1 ATXN2 ATXN8OS EIF4G1 GBA1 GLUD2 MAPT MPZ NIPA1 NR4A2 OPA1 PMP22 SNCA SNCAIP SPAST TBP TRNT WASHC5

Diseases (10) :OMIM:168600 OMIM:182600 OMIM:614251 OMIM:118200 OMIM:600363 OMIM:165500 OMIM:118220 OMIM:168601 OMIM:182601 OMIM:603563
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.