Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of the lymph nodes (HP:0002733)

Parent Node:
Lymphadenopathy (HP:0002716)

..Starting node
..Chronic noninfectious lymphadenopathy (HP:0002730)

Term ID:

2730

Name:

Chronic noninfectious lymphadenopathy

Synonym:

Definition:

A chronic form of lymphadenopathy that is not related to infection.

Comments:

Reference:

HP:0002730

Genes and Diseases:

Child Nodes:

Sister Nodes:

Cervical lymphadenopathy (HP:0025289)

Follicular hyperplasia (HP:0002729)

Generalized lymphadenopathy (HP:0008940)

Mediastinal lymphadenopathy (HP:0100721)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	ABCA1 CL E G H	19	29	ORPHA:31150	Tangier disease	HP:0040282 - Frequent	191
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	ATRX CL E G H	546	886	ORPHA:100075	Neuroendocrine tumor of stomach	HP:0040283 - Occasional	169
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	CASP10 CL E G H	843	1500	ORPHA:3261	Autoimmune lymphoproliferative syndrome	HP:0040281 - Very frequent	87
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	CASP10 CL E G H	843	1500	OMIM:603909	Autoimmune lymphoproliferative syndrome, type IIA	.	87
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	DAXX CL E G H	1616	2681	ORPHA:100075	Neuroendocrine tumor of stomach	HP:0040283 - Occasional
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	FAS CL E G H	355	11920	OMIM:601859	Autoimmune lymphoproliferative syndrome	.	59
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	FAS CL E G H	355	11920	ORPHA:3261	Autoimmune lymphoproliferative syndrome	HP:0040281 - Very frequent	59
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	FASLG CL E G H	356	11936	ORPHA:3261	Autoimmune lymphoproliferative syndrome	HP:0040281 - Very frequent	37
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	FASLG CL E G H	356	11936	OMIM:601859	Autoimmune lymphoproliferative syndrome	.	37
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	FOXE1 CL E G H	2304	3806	ORPHA:319487	Familial papillary or follicular thyroid carcinoma	HP:0040282 - Frequent	9
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	HABP2 CL E G H	3026	4798	ORPHA:319487	Familial papillary or follicular thyroid carcinoma	HP:0040282 - Frequent	58
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	MINPP1 CL E G H	9562	7102	ORPHA:319487	Familial papillary or follicular thyroid carcinoma	HP:0040282 - Frequent	3
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	PRKCD CL E G H	5580	9399	ORPHA:3261	Autoimmune lymphoproliferative syndrome	HP:0040281 - Very frequent	10
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	RASGRP1 CL E G H	10125	9878	ORPHA:3261	Autoimmune lymphoproliferative syndrome	HP:0040281 - Very frequent
HP:0002730	HP:0002730	Chronic noninfectious lymphadenopathy	0	SDHD CL E G H	6392	10683	ORPHA:100093	Carcinoid syndrome	HP:0040283 - Occasional	129

Genes (12) :ABCA1 ATRX CASP10 DAXX FAS FASLG FOXE1 HABP2 MINPP1 PRKCD RASGRP1 SDHD

Diseases (7) :ORPHA:31150 ORPHA:100075 ORPHA:3261 OMIM:603909 OMIM:601859 ORPHA:319487 ORPHA:100093

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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