Human Phenotype Ontology 
Grandparent Node:
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Abnormal nervous system physiology (HP:0012638)help
Parent Node:
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Abnormality of movement (HP:0100022)help
..Starting node
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Primitive reflex (HP:0002476)help
Term ID: 2476
Name: Primitive reflex
Synonym: Archaic reflex; Primitive reflexes
Definition: The primitive reflexes are a group of behavioural motor responses which are found in normal early development, are subsequently inhibited, but may be released from inhibition by cerebral, usually frontal, damage. They are thus part of a broader group of reflexes which reflect release phenomena, such as exaggerated stretch reflexes and extensor plantars. They do however involve more complex motor responses than such simple stretch reflexes, and are often a normal feature in the neonate or infant.
Comments:
Reference: HP:0002476
Genes and Diseases:
 
       Child Nodes:
........expandPalmomental reflex (HP:0030902) help
........expandGrasp reflex (HP:0030903) help
........expandGlabellar reflex (HP:0030904) help
........expandSnout reflex (HP:0030905) help
........expandSuck reflex (HP:0030906) help

 Sister Nodes: 
..expandAbnormal head movements (HP:0002457) help
..expandAbnormal posturing (HP:0002533) help
..expandAbnormal reflex (HP:0031826) help
..expandAstasia (HP:0020037) help
..expandAsterixis (HP:0012164) help
..expandBimanual synkinesia (HP:0001335) help
..expandCerebral palsy (HP:0100021) help
..expandDiminished movement (HP:0002374) help
..expandDyskinesia (HP:0100660) help
..expandDystonia (HP:0001332) help
..expandFrontal release signs (HP:0000743) help
..expandGait disturbance (HP:0001288) help
..expandHyperactivity (HP:0000752) help
..expandHyperkinetic movements (HP:0002487) help
..expandInvoluntary movements (HP:0004305) help
..expandMuscle fibrillation (HP:0010546) help
..expandMyokymia (HP:0002411) help
..expandPostural instability (HP:0002172) help
..expandStooped posture (HP:0025403) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0002476HP:0002476Primitive reflex0CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0002476Primitive reflex0CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0002476Primitive reflex0DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0002476Primitive reflex0DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0002476Primitive reflex0DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0002476Primitive reflex0DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0002476Primitive reflex0GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0002476Primitive reflex0GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0002476Primitive reflex0MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0002476Primitive reflex0MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0002476Primitive reflex0MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0002476Primitive reflex0MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0002476Primitive reflex0PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0002476Primitive reflex0PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0002476Primitive reflex0PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0002476Primitive reflex0PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0002476Primitive reflex0PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0002476Primitive reflex0PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0002476Primitive reflex0SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0002476Primitive reflex0SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0002476Primitive reflex0ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0002476Primitive reflex0ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0002476Primitive reflex0TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0002476Primitive reflex0TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
HP:0002476HP:0030906Suck reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0030903Grasp reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0030905Snout reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0030904Glabellar reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0030902Palmomental reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0030905Snout reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0030904Glabellar reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0030902Palmomental reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11292531603539
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0030906Suck reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0030903Grasp reflex1CTSF CL E G H8722615362Ceroid lipofuscinosis, neuronal, 13615362C3715049OMIM11402531603539
HP:0002476HP:0030904Glabellar reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0030902Palmomental reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0030905Snout reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0030903Grasp reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0030906Suck reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0030903Grasp reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0030906Suck reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM17492976126375
HP:0002476HP:0030904Glabellar reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0030902Palmomental reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0030905Snout reflex1DNMT1 CL E G H1786604121Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant604121C1858804OMIM18322976126375
HP:0002476HP:0030902Palmomental reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0030905Snout reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0030904Glabellar reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0030903Grasp reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0030906Suck reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0030903Grasp reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0030906Suck reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11133006603564
HP:0002476HP:0030902Palmomental reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0030905Snout reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0030904Glabellar reflex1DPM2 CL E G H8818615042Congenital disorder of glycosylation type 1u615042C3554385OMIM11233006603564
HP:0002476HP:0030903Grasp reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0030906Suck reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0030904Glabellar reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0030902Palmomental reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0030905Snout reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0030904Glabellar reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0030902Palmomental reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0030905Snout reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11424367613109
HP:0002476HP:0030903Grasp reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0030906Suck reflex1GM2A CL E G H2760272750Tay-Sachs disease, variant AB272750C0268275OMIM11534367613109
HP:0002476HP:0030902Palmomental reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0030905Snout reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0030904Glabellar reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0030903Grasp reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0030906Suck reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0030903Grasp reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0030906Suck reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14656893157140
HP:0002476HP:0030902Palmomental reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0030905Snout reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0030904Glabellar reflex1MAPT CL E G H4137600274Frontotemporal dementia600274C0338451OMIM14886893157140
HP:0002476HP:0030904Glabellar reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0030902Palmomental reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0030905Snout reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0030903Grasp reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0030906Suck reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0030903Grasp reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0030906Suck reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14656893157140
HP:0002476HP:0030904Glabellar reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0030902Palmomental reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0030905Snout reflex1MAPT CL E G H4137172700Pick's disease172700C0236642OMIM14886893157140
HP:0002476HP:0030906Suck reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0030903Grasp reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0030905Snout reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0030904Glabellar reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0030902Palmomental reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0030905Snout reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0030904Glabellar reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0030902Palmomental reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM167226270613629
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0030906Suck reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0030903Grasp reflex1PIEZO2 CL E G H63895248700Marden-Walker syndrome248700C0796033OMIM170926270613629
HP:0002476HP:0030906Suck reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0030903Grasp reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0030905Snout reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0030904Glabellar reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0030902Palmomental reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0030905Snout reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0030904Glabellar reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0030902Palmomental reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14089508104311
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0030906Suck reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0030903Grasp reflex1PSEN1 CL E G H5663600274Frontotemporal dementia600274C0338451OMIM14319508104311
HP:0002476HP:0030903Grasp reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0030906Suck reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0030904Glabellar reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0030902Palmomental reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0030905Snout reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0030904Glabellar reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0030902Palmomental reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0030905Snout reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14089508104311
HP:0002476HP:0030903Grasp reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0030906Suck reflex1PSEN1 CL E G H5663172700Pick's disease172700C0236642OMIM14319508104311
HP:0002476HP:0030906Suck reflex1SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0030903Grasp reflex1SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0030905Snout reflex1SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0030904Glabellar reflex1SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0030902Palmomental reflex1SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0030905Snout reflex1SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0030904Glabellar reflex1SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0030902Palmomental reflex1SPG21 CL E G H51324101001ORPHA112220373608181
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0030906Suck reflex1SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0030903Grasp reflex1SPG21 CL E G H51324101001ORPHA114020373608181
HP:0002476HP:0030903Grasp reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0030906Suck reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0030904Glabellar reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0030902Palmomental reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0030905Snout reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0030904Glabellar reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0030902Palmomental reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0030905Snout reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM118110866606494
HP:0002476HP:0030903Grasp reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0030906Suck reflex1ST3GAL3 CL E G H6487615006Early infantile epileptic encephalopathy 15615006C3554316OMIM122910866606494
HP:0002476HP:0030902Palmomental reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0030905Snout reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0030904Glabellar reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0030903Grasp reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
HP:0002476HP:0030906Suck reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
HP:0002476HP:0030903Grasp reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0030906Suck reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM15212449604142
HP:0002476HP:0030902Palmomental reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
HP:0002476HP:0030905Snout reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
HP:0002476HP:0030904Glabellar reflex1TYROBP CL E G H7305221770Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy221770C1857316OMIM17312449604142
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002476HP:0002476Primitive reflex0ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0002476Primitive reflex0ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0002476Primitive reflex0DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0002476Primitive reflex0DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0002476Primitive reflex0HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0002476Primitive reflex0HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0002476Primitive reflex0HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0002476Primitive reflex0HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0002476Primitive reflex0JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0002476Primitive reflex0JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0002476Primitive reflex0SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0002476Primitive reflex0SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181
HP:0002476HP:0030903Grasp reflex1ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0030906Suck reflex1ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0030904Glabellar reflex1ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0030902Palmomental reflex1ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0030905Snout reflex1ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0030904Glabellar reflex1ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0030902Palmomental reflex1ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0030905Snout reflex1ALDH18A1 CL E G H5832447760ORPHA03469722138250
HP:0002476HP:0030903Grasp reflex1ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0030906Suck reflex1ALDH18A1 CL E G H5832447760ORPHA03929722138250
HP:0002476HP:0030904Glabellar reflex1DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0030902Palmomental reflex1DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0030905Snout reflex1DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0030906Suck reflex1DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0030903Grasp reflex1DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0030903Grasp reflex1DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0030906Suck reflex1DNMT1 CL E G H1786314404ORPHA07492976126375
HP:0002476HP:0030904Glabellar reflex1DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0030902Palmomental reflex1DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0030905Snout reflex1DNMT1 CL E G H1786314404ORPHA08322976126375
HP:0002476HP:0030904Glabellar reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0030902Palmomental reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0030905Snout reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0030906Suck reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0030903Grasp reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0030903Grasp reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0030906Suck reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA04774801600890
HP:0002476HP:0030904Glabellar reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0030902Palmomental reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0030905Snout reflex1HADHA CL E G H3030746Apert like polydactyly syndromeORPHA05274801600890
HP:0002476HP:0030903Grasp reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0030906Suck reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0030904Glabellar reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0030902Palmomental reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0030905Snout reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0030904Glabellar reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0030902Palmomental reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0030905Snout reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02134803143450
HP:0002476HP:0030903Grasp reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0030906Suck reflex1HADHB CL E G H3032746Apert like polydactyly syndromeORPHA02424803143450
HP:0002476HP:0030902Palmomental reflex1JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0030905Snout reflex1JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0030904Glabellar reflex1JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0030903Grasp reflex1JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0030906Suck reflex1JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0030903Grasp reflex1JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0030906Suck reflex1JPH3 CL E G H5733898934ORPHA012214203605268
HP:0002476HP:0030902Palmomental reflex1JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0030905Snout reflex1JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0030904Glabellar reflex1JPH3 CL E G H5733898934ORPHA012314203605268
HP:0002476HP:0030904Glabellar reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0030902Palmomental reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0030905Snout reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0030903Grasp reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181
HP:0002476HP:0030906Suck reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181
HP:0002476HP:0030903Grasp reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0032549Persistent asymmetrical tonic neck reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0030906Suck reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM012220373608181
HP:0002476HP:0030904Glabellar reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181
HP:0002476HP:0030902Palmomental reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181
HP:0002476HP:0030905Snout reflex1SPG21 CL E G H51324248900Mast syndrome248900C1855346OMIM014020373608181


Genes (18) :ALDH18A1 CTSF DNMT1 DPM2 ERLIN2 GLRB GM2A HADHA HADHB JPH3 MAPT NGLY1 PIEZO2 PSEN1 SPG21 ST3GAL3 TUBB3 TYROBP

Diseases (20) :447760 615362 314404 604121 615042 272750 746 98934 600274 172700 248700 101001 248900 615006 221770 209951 614619 309246 615273 300570
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.