Human Phenotype Ontology 
Grandparent Node:
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Hypopigmentation of hair (HP:0005599)help
Parent Node:
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Patchy hypopigmentation of hair (HP:0011365)help
..Starting node
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White forelock (HP:0002211)help
Term ID: 2211
Name: White forelock
Synonym: Poliosis of anterior hair; Poliosis of forelock hair; White part of hair above forehead
Definition: A triangular depigmented region of white hairs located in the anterior midline of the scalp.
Comments:
Reference: HP:0002211
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandPoliosis (HP:0002290) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002211HP:0002211White forelock0EDN3 CL E G H19083178OMIM:613265Waardenburg syndrome, type 4B.67
HP:0002211HP:0002211White forelock0EDN3 CL E G H19083178ORPHA:897Waardenburg-Shah syndromeHP:0040281 - Very frequent67
HP:0002211HP:0002211White forelock0EDNRB CL E G H19103180ORPHA:895Waardenburg syndrome type 2HP:0040282 - Frequent55
HP:0002211HP:0002211White forelock0EDNRB CL E G H19103180OMIM:277580Waardenburg-Shah syndrome.55
HP:0002211HP:0002211White forelock0EDNRB CL E G H19103180ORPHA:897Waardenburg-Shah syndromeHP:0040281 - Very frequent55
HP:0002211HP:0002211White forelock0KIT CL E G H38156342OMIM:172800Piebald trait.327
HP:0002211HP:0002211White forelock0KIT CL E G H38156342ORPHA:2884PiebaldismHP:0040281 - Very frequent327
HP:0002211HP:0002211White forelock0KITLG CL E G H42546343OMIM:6199479
HP:0002211HP:0002211White forelock0KITLG CL E G H42546343ORPHA:895Waardenburg syndrome type 2HP:0040282 - Frequent9
HP:0002211HP:0002211White forelock0LMNA CL E G H40006636ORPHA:79474Atypical Werner syndromeHP:0040281 - Very frequent645
HP:0002211HP:0002211White forelock0MITF CL E G H42867105ORPHA:895Waardenburg syndrome type 2HP:0040282 - Frequent91
HP:0002211HP:0002211White forelock0MITF CL E G H42867105OMIM:193510Waardenburg syndrome, type 2A.91
HP:0002211HP:0002211White forelock0MITF CL E G H42867105ORPHA:897Waardenburg-Shah syndromeHP:0040281 - Very frequent91
HP:0002211HP:0002211White forelock0PAX3 CL E G H50778617ORPHA:894Waardenburg syndrome type 1HP:0040281 - Very frequent59
HP:0002211HP:0002211White forelock0PAX3 CL E G H50778617OMIM:193500Waardenburg syndrome, type 1.59
HP:0002211HP:0002211White forelock0PAX3 CL E G H50778617OMIM:148820Waardenburg syndrome, type 3.59
HP:0002211HP:0002211White forelock0PEPD CL E G H51848840ORPHA:742Prolidase deficiencyHP:0040282 - Frequent66
HP:0002211HP:0002211White forelock0SNAI2 CL E G H659111094OMIM:172800Piebald trait.19
HP:0002211HP:0002211White forelock0SNAI2 CL E G H659111094ORPHA:2884PiebaldismHP:0040281 - Very frequent19
HP:0002211HP:0002211White forelock0SNAI2 CL E G H659111094ORPHA:895Waardenburg syndrome type 2HP:0040282 - Frequent19
HP:0002211HP:0002211White forelock0SOX10 CL E G H666311190OMIM:609136Peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease.61
HP:0002211HP:0002211White forelock0SOX10 CL E G H666311190ORPHA:895Waardenburg syndrome type 2HP:0040282 - Frequent61
HP:0002211HP:0002211White forelock0SOX10 CL E G H666311190OMIM:611584Waardenburg syndrome, type 2E.61
HP:0002211HP:0002211White forelock0SOX10 CL E G H666311190OMIM:613266Waardenburg syndrome, type 4C.61
HP:0002211HP:0002211White forelock0SOX10 CL E G H666311190ORPHA:897Waardenburg-Shah syndromeHP:0040281 - Very frequent61
HP:0002211HP:0002211White forelock0TERT CL E G H701511730OMIM:613989Dyskeratosis congenita, autosomal dominant 2238
HP:0002211HP:0002211White forelock0TFAP2A CL E G H702011742OMIM:113620Branchiooculofacial syndrome.12
HP:0002211HP:0002211White forelock0TYR CL E G H729912442ORPHA:895Waardenburg syndrome type 2HP:0040282 - Frequent146
HP:0002211HP:0002211White forelock0WRN CL E G H748612791ORPHA:902Werner syndromeHP:0040281 - Very frequent310


Genes (14) :EDN3 EDNRB KIT KITLG LMNA MITF PAX3 PEPD SNAI2 SOX10 TERT TFAP2A TYR WRN

Diseases (19) :OMIM:613265 ORPHA:897 ORPHA:895 OMIM:277580 OMIM:172800 ORPHA:2884 OMIM:619947 ORPHA:79474 OMIM:193510 ORPHA:894 OMIM:193500 OMIM:148820 ORPHA:742 OMIM:609136 OMIM:611584 OMIM:613266 OMIM:613989 OMIM:113620 ORPHA:902
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.