Human Phenotype Ontology 
Grandparent Node:
expand
Abnormality of movement (HP:0100022)help
Parent Node:
expand
Hyperreflexia (HP:0001347)help
Parent Node:
expand
Involuntary movements (HP:0004305)help
..Starting node
..expand
Clonus (HP:0002169)help
Term ID: 2169
Name: Clonus
Synonym: Involuntary rhythmic muscular contractions and relaxations
Definition: A series of rhythmic and involuntary muscle contractions (at a frequency of about 5 to 7 Hz) that occur in response to an abruptly applied and sustained stretch.
Comments:
Reference: HP:0002169
Genes and Diseases:
 
       Child Nodes:
........expandAnkle clonus (HP:0011448) help
........expandKnee clonus (HP:0011449) help
........expandElbow clonus (HP:0011728) help

 Sister Nodes: 
..expandAthetosis (HP:0002305) help
..expandChorea (HP:0002072) help
..expandFasciculations (HP:0002380) help
..expandHemiballismus (HP:0100248) help
..expandIntermittent painful muscle spasms (HP:0011964) help
..expandMyoclonus (HP:0001336) help
..expandParoxysmal dyskinesia (HP:0007166) help
..expandSelf-mutilation of tongue and lips due to involuntary movements (HP:0008767) help
..expandStereotypy (HP:0000733) help
..expandTics (HP:0100033) help
..expandTremor (HP:0001337) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0002169HP:0002169Clonus0ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM125148300135
HP:0002169HP:0002169Clonus0ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM124648300135
HP:0002169HP:0002169Clonus0AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1230469102771
HP:0002169HP:0002169Clonus0AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1172469102771
HP:0002169HP:0002169Clonus0BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM184721701614506
HP:0002169HP:0002169Clonus0BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM172521701614506
HP:0002169HP:0002169Clonus0C12orf65 CL E G H91574615035Spastic paraplegia 55, autosomal recessive615035C3539506OMIM126784613541
HP:0002169HP:0002169Clonus0CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1851527601047
HP:0002169HP:0002169Clonus0CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1811527601047
HP:0002169HP:0002169Clonus0CCT5 CL E G H22948139578ORPHA13061618610150
HP:0002169HP:0002169Clonus0CCT5 CL E G H22948139578ORPHA12931618610150
HP:0002169HP:0002169Clonus0CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM13061618610150
HP:0002169HP:0002169Clonus0CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM12931618610150
HP:0002169HP:0002169Clonus0ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM18416947611604
HP:0002169HP:0002169Clonus0ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM15916947611604
HP:0002169HP:0002169Clonus0HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM14326938614908
HP:0002169HP:0002169Clonus0HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM13526938614908
HP:0002169HP:0002169Clonus0KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1147618865608167
HP:0002169HP:0002169Clonus0KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1130318865608167
HP:0002169HP:0002169Clonus0KIF1C CL E G H10749397946ORPHA13356317603060
HP:0002169HP:0002169Clonus0KIF1C CL E G H10749397946ORPHA12866317603060
HP:0002169HP:0002169Clonus0MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12822375603810
HP:0002169HP:0002169Clonus0MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12482375603810
HP:0002169HP:0002169Clonus0MT-CO1 CL E G H4512550ORPHA17419516030
HP:0002169HP:0002169Clonus0MT-CO2 CL E G H4513550ORPHA17421516040
HP:0002169HP:0002169Clonus0MT-CO3 CL E G H4514550ORPHA17422516050
HP:0002169HP:0002169Clonus0MT-ND1 CL E G H4535550ORPHA17455516000
HP:0002169HP:0002169Clonus0MT-ND4 CL E G H4538550ORPHA17459516003
HP:0002169HP:0002169Clonus0MT-ND5 CL E G H4540550ORPHA17461516005
HP:0002169HP:0002169Clonus0MT-ND6 CL E G H4541550ORPHA17462516006
HP:0002169HP:0002169Clonus0MT-TF CL E G H4558550ORPHA17481590070
HP:0002169HP:0002169Clonus0MT-TH CL E G H4564550ORPHA17487590040
HP:0002169HP:0002169Clonus0MT-TL1 CL E G H4567550ORPHA17490590050
HP:0002169HP:0002169Clonus0MT-TQ CL E G H4572550ORPHA17495590030
HP:0002169HP:0002169Clonus0MT-TS1 CL E G H4574550ORPHA17497590080
HP:0002169HP:0002169Clonus0MT-TS2 CL E G H4575550ORPHA17498590085
HP:0002169HP:0002169Clonus0MT-TW CL E G H4578550ORPHA17501590095
HP:0002169HP:0002169Clonus0NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM155717043608145
HP:0002169HP:0002169Clonus0NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM152617043608145
HP:0002169HP:0002169Clonus0OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14758108300535
HP:0002169HP:0002169Clonus0OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14258108300535
HP:0002169HP:0002169Clonus0OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM119121652607649
HP:0002169HP:0002169Clonus0OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM114621652607649
HP:0002169HP:0002169Clonus0PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM16438636608786
HP:0002169HP:0002169Clonus0PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM15748636608786
HP:0002169HP:0002169Clonus0PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1829457604436
HP:0002169HP:0002169Clonus0PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1809457604436
HP:0002169HP:0002169Clonus0PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13513420617413
HP:0002169HP:0002169Clonus0PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13413420617413
HP:0002169HP:0002169Clonus0RTN2 CL E G H6253100993ORPHA117210468603183
HP:0002169HP:0002169Clonus0RTN2 CL E G H6253100993ORPHA115210468603183
HP:0002169HP:0002169Clonus0SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM132930605613009
HP:0002169HP:0002169Clonus0SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM129230605613009
HP:0002169HP:0002169Clonus0SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM131810923300095
HP:0002169HP:0002169Clonus0SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM129010923300095
HP:0002169HP:0002169Clonus0SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM130410985603861
HP:0002169HP:0002169Clonus0SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM128210985603861
HP:0002169HP:0002169Clonus0SLC33A1 CL E G H9197171863ORPHA112695603690
HP:0002169HP:0002169Clonus0SLC33A1 CL E G H9197171863ORPHA110195603690
HP:0002169HP:0002169Clonus0SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM112611056601019
HP:0002169HP:0002169Clonus0SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM19111056601019
HP:0002169HP:0002169Clonus0TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM155025439616830
HP:0002169HP:0002169Clonus0TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM148025439616830
HP:0002169HP:0002169Clonus0TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM17129947608112
HP:0002169HP:0002169Clonus0TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM14029947608112
HP:0002169HP:0002169Clonus0TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM122828422608753
HP:0002169HP:0002169Clonus0TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM120828422608753
HP:0002169HP:0002169Clonus0UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12226941610554
HP:0002169HP:0002169Clonus0UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12026941610554
HP:0002169HP:0002169Clonus0USP8 CL E G H9101401795ORPHA111512631603158
HP:0002169HP:0002169Clonus0USP8 CL E G H9101401795ORPHA19812631603158
HP:0002169HP:0002169Clonus0VPS37A CL E G H137492319199ORPHA118824928609927
HP:0002169HP:0002169Clonus0VPS37A CL E G H137492319199ORPHA117324928609927
HP:0002169HP:0002169Clonus0VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM118824928609927
HP:0002169HP:0002169Clonus0VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM117324928609927
HP:0002169HP:0002169Clonus0ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1145720761612012
HP:0002169HP:0002169Clonus0ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1126420761612012
HP:0002169HP:0011448Ankle clonus1ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM125148300135
HP:0002169HP:0011449Knee clonus1ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM125148300135
HP:0002169HP:0011448Ankle clonus1ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM124648300135
HP:0002169HP:0011449Knee clonus1ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM124648300135
HP:0002169HP:0011728Elbow clonus1ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM125148300135
HP:0002169HP:0011728Elbow clonus1ABCB7 CL E G H22301310Anemia sideroblastic and spinocerebellar ataxia301310C1845028OMIM124648300135
HP:0002169HP:0011448Ankle clonus1AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1230469102771
HP:0002169HP:0011449Knee clonus1AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1230469102771
HP:0002169HP:0011448Ankle clonus1AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1172469102771
HP:0002169HP:0011449Knee clonus1AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1172469102771
HP:0002169HP:0011728Elbow clonus1AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1230469102771
HP:0002169HP:0011728Elbow clonus1AMPD2 CL E G H271615809Pontocerebellar hypoplasia, type 9615809C4014354OMIM1172469102771
HP:0002169HP:0011448Ankle clonus1BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM184721701614506
HP:0002169HP:0011449Knee clonus1BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM184721701614506
HP:0002169HP:0011448Ankle clonus1BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM172521701614506
HP:0002169HP:0011449Knee clonus1BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM172521701614506
HP:0002169HP:0011728Elbow clonus1BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM184721701614506
HP:0002169HP:0011728Elbow clonus1BRAT1 CL E G H221927614498Rigidity and multifocal seizure syndrome, lethal neonatal614498C3281029OMIM172521701614506
HP:0002169HP:0011728Elbow clonus1C12orf65 CL E G H91574615035Spastic paraplegia 55, autosomal recessive615035C3539506OMIM126784613541
HP:0002169HP:0011448Ankle clonus1C12orf65 CL E G H91574615035Spastic paraplegia 55, autosomal recessive615035C3539506OMIM126784613541
HP:0002169HP:0011449Knee clonus1C12orf65 CL E G H91574615035Spastic paraplegia 55, autosomal recessive615035C3539506OMIM126784613541
HP:0002169HP:0011449Knee clonus1CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1851527601047
HP:0002169HP:0011448Ankle clonus1CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1851527601047
HP:0002169HP:0011449Knee clonus1CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1811527601047
HP:0002169HP:0011448Ankle clonus1CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1811527601047
HP:0002169HP:0011728Elbow clonus1CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1851527601047
HP:0002169HP:0011728Elbow clonus1CAV1 CL E G H857606721Partial lipodystrophy, congenital cataracts, and neurodegeneration syndrome606721C1847582OMIM1811527601047
HP:0002169HP:0011448Ankle clonus1CCT5 CL E G H22948139578ORPHA13061618610150
HP:0002169HP:0011449Knee clonus1CCT5 CL E G H22948139578ORPHA13061618610150
HP:0002169HP:0011448Ankle clonus1CCT5 CL E G H22948139578ORPHA12931618610150
HP:0002169HP:0011449Knee clonus1CCT5 CL E G H22948139578ORPHA12931618610150
HP:0002169HP:0011728Elbow clonus1CCT5 CL E G H22948139578ORPHA13061618610150
HP:0002169HP:0011728Elbow clonus1CCT5 CL E G H22948139578ORPHA12931618610150
HP:0002169HP:0011448Ankle clonus1CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM13061618610150
HP:0002169HP:0011449Knee clonus1CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM13061618610150
HP:0002169HP:0011448Ankle clonus1CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM12931618610150
HP:0002169HP:0011449Knee clonus1CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM12931618610150
HP:0002169HP:0011728Elbow clonus1CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM13061618610150
HP:0002169HP:0011728Elbow clonus1CCT5 CL E G H22948256840Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive256840C1850395OMIM12931618610150
HP:0002169HP:0011448Ankle clonus1ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM18416947611604
HP:0002169HP:0011449Knee clonus1ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM18416947611604
HP:0002169HP:0011448Ankle clonus1ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM15916947611604
HP:0002169HP:0011449Knee clonus1ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM15916947611604
HP:0002169HP:0011728Elbow clonus1ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM18416947611604
HP:0002169HP:0011728Elbow clonus1ERLIN1 CL E G H10613615681Spastic paraplegia 62, autosomal recessive615681C4284588OMIM15916947611604
HP:0002169HP:0011448Ankle clonus1HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM14326938614908
HP:0002169HP:0011449Knee clonus1HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM14326938614908
HP:0002169HP:0011448Ankle clonus1HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM13526938614908
HP:0002169HP:0011449Knee clonus1HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM13526938614908
HP:0002169HP:0011728Elbow clonus1HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM14326938614908
HP:0002169HP:0011728Elbow clonus1HIKESHI CL E G H51501616881Leukodystrophy, hypomyelinating, 13616881C4225170OMIM13526938614908
HP:0002169HP:0011448Ankle clonus1KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1147618865608167
HP:0002169HP:0011449Knee clonus1KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1147618865608167
HP:0002169HP:0011448Ankle clonus1KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1130318865608167
HP:0002169HP:0011449Knee clonus1KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1130318865608167
HP:0002169HP:0011728Elbow clonus1KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1147618865608167
HP:0002169HP:0011728Elbow clonus1KCNT1 CL E G H57582614959Early infantile epileptic encephalopathy 14614959C3554195OMIM1130318865608167
HP:0002169HP:0011449Knee clonus1KIF1C CL E G H10749397946ORPHA13356317603060
HP:0002169HP:0011448Ankle clonus1KIF1C CL E G H10749397946ORPHA13356317603060
HP:0002169HP:0011449Knee clonus1KIF1C CL E G H10749397946ORPHA12866317603060
HP:0002169HP:0011448Ankle clonus1KIF1C CL E G H10749397946ORPHA12866317603060
HP:0002169HP:0011728Elbow clonus1KIF1C CL E G H10749397946ORPHA13356317603060
HP:0002169HP:0011728Elbow clonus1KIF1C CL E G H10749397946ORPHA12866317603060
HP:0002169HP:0011449Knee clonus1MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12822375603810
HP:0002169HP:0011448Ankle clonus1MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12822375603810
HP:0002169HP:0011448Ankle clonus1MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12482375603810
HP:0002169HP:0011449Knee clonus1MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12482375603810
HP:0002169HP:0011728Elbow clonus1MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12822375603810
HP:0002169HP:0011728Elbow clonus1MED17 CL E G H9440613668Microcephaly, postnatal progressive, with seizures and brain atrophy613668C3150921OMIM12482375603810
HP:0002169HP:0011728Elbow clonus1MT-CO1 CL E G H4512550ORPHA17419516030
HP:0002169HP:0011448Ankle clonus1MT-CO1 CL E G H4512550ORPHA17419516030
HP:0002169HP:0011449Knee clonus1MT-CO1 CL E G H4512550ORPHA17419516030
HP:0002169HP:0011728Elbow clonus1MT-CO2 CL E G H4513550ORPHA17421516040
HP:0002169HP:0011448Ankle clonus1MT-CO2 CL E G H4513550ORPHA17421516040
HP:0002169HP:0011449Knee clonus1MT-CO2 CL E G H4513550ORPHA17421516040
HP:0002169HP:0011728Elbow clonus1MT-CO3 CL E G H4514550ORPHA17422516050
HP:0002169HP:0011448Ankle clonus1MT-CO3 CL E G H4514550ORPHA17422516050
HP:0002169HP:0011449Knee clonus1MT-CO3 CL E G H4514550ORPHA17422516050
HP:0002169HP:0011728Elbow clonus1MT-ND1 CL E G H4535550ORPHA17455516000
HP:0002169HP:0011448Ankle clonus1MT-ND1 CL E G H4535550ORPHA17455516000
HP:0002169HP:0011449Knee clonus1MT-ND1 CL E G H4535550ORPHA17455516000
HP:0002169HP:0011728Elbow clonus1MT-ND4 CL E G H4538550ORPHA17459516003
HP:0002169HP:0011448Ankle clonus1MT-ND4 CL E G H4538550ORPHA17459516003
HP:0002169HP:0011449Knee clonus1MT-ND4 CL E G H4538550ORPHA17459516003
HP:0002169HP:0011728Elbow clonus1MT-ND5 CL E G H4540550ORPHA17461516005
HP:0002169HP:0011448Ankle clonus1MT-ND5 CL E G H4540550ORPHA17461516005
HP:0002169HP:0011449Knee clonus1MT-ND5 CL E G H4540550ORPHA17461516005
HP:0002169HP:0011728Elbow clonus1MT-ND6 CL E G H4541550ORPHA17462516006
HP:0002169HP:0011448Ankle clonus1MT-ND6 CL E G H4541550ORPHA17462516006
HP:0002169HP:0011449Knee clonus1MT-ND6 CL E G H4541550ORPHA17462516006
HP:0002169HP:0011728Elbow clonus1MT-TF CL E G H4558550ORPHA17481590070
HP:0002169HP:0011448Ankle clonus1MT-TF CL E G H4558550ORPHA17481590070
HP:0002169HP:0011449Knee clonus1MT-TF CL E G H4558550ORPHA17481590070
HP:0002169HP:0011728Elbow clonus1MT-TH CL E G H4564550ORPHA17487590040
HP:0002169HP:0011448Ankle clonus1MT-TH CL E G H4564550ORPHA17487590040
HP:0002169HP:0011449Knee clonus1MT-TH CL E G H4564550ORPHA17487590040
HP:0002169HP:0011728Elbow clonus1MT-TL1 CL E G H4567550ORPHA17490590050
HP:0002169HP:0011448Ankle clonus1MT-TL1 CL E G H4567550ORPHA17490590050
HP:0002169HP:0011449Knee clonus1MT-TL1 CL E G H4567550ORPHA17490590050
HP:0002169HP:0011728Elbow clonus1MT-TQ CL E G H4572550ORPHA17495590030
HP:0002169HP:0011448Ankle clonus1MT-TQ CL E G H4572550ORPHA17495590030
HP:0002169HP:0011449Knee clonus1MT-TQ CL E G H4572550ORPHA17495590030
HP:0002169HP:0011728Elbow clonus1MT-TS1 CL E G H4574550ORPHA17497590080
HP:0002169HP:0011448Ankle clonus1MT-TS1 CL E G H4574550ORPHA17497590080
HP:0002169HP:0011449Knee clonus1MT-TS1 CL E G H4574550ORPHA17497590080
HP:0002169HP:0011728Elbow clonus1MT-TS2 CL E G H4575550ORPHA17498590085
HP:0002169HP:0011448Ankle clonus1MT-TS2 CL E G H4575550ORPHA17498590085
HP:0002169HP:0011449Knee clonus1MT-TS2 CL E G H4575550ORPHA17498590085
HP:0002169HP:0011728Elbow clonus1MT-TW CL E G H4578550ORPHA17501590095
HP:0002169HP:0011448Ankle clonus1MT-TW CL E G H4578550ORPHA17501590095
HP:0002169HP:0011449Knee clonus1MT-TW CL E G H4578550ORPHA17501590095
HP:0002169HP:0011448Ankle clonus1NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM155717043608145
HP:0002169HP:0011449Knee clonus1NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM155717043608145
HP:0002169HP:0011448Ankle clonus1NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM152617043608145
HP:0002169HP:0011449Knee clonus1NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM152617043608145
HP:0002169HP:0011728Elbow clonus1NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM155717043608145
HP:0002169HP:0011728Elbow clonus1NIPA1 CL E G H123606600363Spastic paraplegia 6600363C1838192OMIM152617043608145
HP:0002169HP:0011449Knee clonus1OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14758108300535
HP:0002169HP:0011448Ankle clonus1OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14758108300535
HP:0002169HP:0011449Knee clonus1OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14258108300535
HP:0002169HP:0011448Ankle clonus1OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14258108300535
HP:0002169HP:0011728Elbow clonus1OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14758108300535
HP:0002169HP:0011728Elbow clonus1OCRL CL E G H4952534Acute myeloblastic leukemia without maturationORPHA14258108300535
HP:0002169HP:0011449Knee clonus1OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM119121652607649
HP:0002169HP:0011448Ankle clonus1OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM119121652607649
HP:0002169HP:0011449Knee clonus1OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM114621652607649
HP:0002169HP:0011448Ankle clonus1OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM114621652607649
HP:0002169HP:0011728Elbow clonus1OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM119121652607649
HP:0002169HP:0011728Elbow clonus1OSTM1 CL E G H28962259720Osteopetrosis, autosomal recessive 5259720C1968603OMIM114621652607649
HP:0002169HP:0011448Ankle clonus1PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM16438636608786
HP:0002169HP:0011449Knee clonus1PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM16438636608786
HP:0002169HP:0011448Ankle clonus1PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM15748636608786
HP:0002169HP:0011449Knee clonus1PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM15748636608786
HP:0002169HP:0011728Elbow clonus1PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM16438636608786
HP:0002169HP:0011728Elbow clonus1PC CL E G H5091266150Pyruvate carboxylase deficiency266150C0034341OMIM15748636608786
HP:0002169HP:0011449Knee clonus1PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1829457604436
HP:0002169HP:0011448Ankle clonus1PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1829457604436
HP:0002169HP:0011449Knee clonus1PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1809457604436
HP:0002169HP:0011448Ankle clonus1PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1809457604436
HP:0002169HP:0011728Elbow clonus1PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1829457604436
HP:0002169HP:0011728Elbow clonus1PLPBP CL E G H11212617290Epilepsy, early-onset, vitamin b6-dependent617290C4310632OMIM1809457604436
HP:0002169HP:0011448Ankle clonus1PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13513420617413
HP:0002169HP:0011449Knee clonus1PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13513420617413
HP:0002169HP:0011448Ankle clonus1PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13413420617413
HP:0002169HP:0011449Knee clonus1PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13413420617413
HP:0002169HP:0011728Elbow clonus1PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13513420617413
HP:0002169HP:0011728Elbow clonus1PRUNE1 CL E G H58497617481Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies617481C4479566OMIM13413420617413
HP:0002169HP:0011448Ankle clonus1RTN2 CL E G H6253100993ORPHA117210468603183
HP:0002169HP:0011449Knee clonus1RTN2 CL E G H6253100993ORPHA117210468603183
HP:0002169HP:0011448Ankle clonus1RTN2 CL E G H6253100993ORPHA115210468603183
HP:0002169HP:0011449Knee clonus1RTN2 CL E G H6253100993ORPHA115210468603183
HP:0002169HP:0011728Elbow clonus1RTN2 CL E G H6253100993ORPHA117210468603183
HP:0002169HP:0011728Elbow clonus1RTN2 CL E G H6253100993ORPHA115210468603183
HP:0002169HP:0011448Ankle clonus1SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM132930605613009
HP:0002169HP:0011449Knee clonus1SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM132930605613009
HP:0002169HP:0011448Ankle clonus1SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM129230605613009
HP:0002169HP:0011449Knee clonus1SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM129230605613009
HP:0002169HP:0011728Elbow clonus1SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM132930605613009
HP:0002169HP:0011728Elbow clonus1SEPSECS CL E G H51091613811Pontocerebellar hypoplasia type 2D613811C3151140OMIM129230605613009
HP:0002169HP:0011448Ankle clonus1SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM131810923300095
HP:0002169HP:0011449Knee clonus1SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM131810923300095
HP:0002169HP:0011448Ankle clonus1SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM129010923300095
HP:0002169HP:0011449Knee clonus1SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM129010923300095
HP:0002169HP:0011728Elbow clonus1SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM131810923300095
HP:0002169HP:0011728Elbow clonus1SLC16A2 CL E G H6567300523Allan-Herndon-Dudley syndrome300523C0795889OMIM129010923300095
HP:0002169HP:0011448Ankle clonus1SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM130410985603861
HP:0002169HP:0011449Knee clonus1SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM130410985603861
HP:0002169HP:0011448Ankle clonus1SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM128210985603861
HP:0002169HP:0011449Knee clonus1SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM128210985603861
HP:0002169HP:0011728Elbow clonus1SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM130410985603861
HP:0002169HP:0011728Elbow clonus1SLC25A15 CL E G H10166238970Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome238970C0268540OMIM128210985603861
HP:0002169HP:0011448Ankle clonus1SLC33A1 CL E G H9197171863ORPHA112695603690
HP:0002169HP:0011449Knee clonus1SLC33A1 CL E G H9197171863ORPHA112695603690
HP:0002169HP:0011449Knee clonus1SLC33A1 CL E G H9197171863ORPHA110195603690
HP:0002169HP:0011448Ankle clonus1SLC33A1 CL E G H9197171863ORPHA110195603690
HP:0002169HP:0011728Elbow clonus1SLC33A1 CL E G H9197171863ORPHA112695603690
HP:0002169HP:0011728Elbow clonus1SLC33A1 CL E G H9197171863ORPHA110195603690
HP:0002169HP:0011448Ankle clonus1SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM112611056601019
HP:0002169HP:0011449Knee clonus1SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM112611056601019
HP:0002169HP:0011448Ankle clonus1SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM19111056601019
HP:0002169HP:0011449Knee clonus1SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM19111056601019
HP:0002169HP:0011728Elbow clonus1SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM112611056601019
HP:0002169HP:0011728Elbow clonus1SLC6A9 CL E G H6536617301Glycine encephalopathy with normal serum glycine617301C4310943OMIM19111056601019
HP:0002169HP:0011448Ankle clonus1TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM155025439616830
HP:0002169HP:0011449Knee clonus1TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM155025439616830
HP:0002169HP:0011449Knee clonus1TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM148025439616830
HP:0002169HP:0011448Ankle clonus1TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM148025439616830
HP:0002169HP:0011728Elbow clonus1TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM155025439616830
HP:0002169HP:0011728Elbow clonus1TANGO2 CL E G H128989616878TANGO2-Related Metabolic Encephalopathy and Arrhythmias616878C4225171OMIM148025439616830
HP:0002169HP:0011448Ankle clonus1TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM17129947608112
HP:0002169HP:0011449Knee clonus1TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM17129947608112
HP:0002169HP:0011449Knee clonus1TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM14029947608112
HP:0002169HP:0011448Ankle clonus1TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM14029947608112
HP:0002169HP:0011728Elbow clonus1TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM17129947608112
HP:0002169HP:0011728Elbow clonus1TRAK1 CL E G H22906618201EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 68618201OMIM14029947608112
HP:0002169HP:0011448Ankle clonus1TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM122828422608753
HP:0002169HP:0011449Knee clonus1TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM122828422608753
HP:0002169HP:0011448Ankle clonus1TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM120828422608753
HP:0002169HP:0011449Knee clonus1TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM120828422608753
HP:0002169HP:0011728Elbow clonus1TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM122828422608753
HP:0002169HP:0011728Elbow clonus1TSEN2 CL E G H80746612389Pontocerebellar hypoplasia type 2B612389C2676466OMIM120828422608753
HP:0002169HP:0011448Ankle clonus1UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12226941610554
HP:0002169HP:0011449Knee clonus1UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12226941610554
HP:0002169HP:0011448Ankle clonus1UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12026941610554
HP:0002169HP:0011449Knee clonus1UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12026941610554
HP:0002169HP:0011728Elbow clonus1UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12226941610554
HP:0002169HP:0011728Elbow clonus1UFC1 CL E G H51506618076NEURODEVELOPMENTAL DISORDER WITH SPASTICITY AND POOR GROWTH618076CN252685OMIM12026941610554
HP:0002169HP:0011448Ankle clonus1USP8 CL E G H9101401795ORPHA111512631603158
HP:0002169HP:0011449Knee clonus1USP8 CL E G H9101401795ORPHA111512631603158
HP:0002169HP:0011448Ankle clonus1USP8 CL E G H9101401795ORPHA19812631603158
HP:0002169HP:0011449Knee clonus1USP8 CL E G H9101401795ORPHA19812631603158
HP:0002169HP:0011728Elbow clonus1USP8 CL E G H9101401795ORPHA111512631603158
HP:0002169HP:0011728Elbow clonus1USP8 CL E G H9101401795ORPHA19812631603158
HP:0002169HP:0011448Ankle clonus1VPS37A CL E G H137492319199ORPHA118824928609927
HP:0002169HP:0011449Knee clonus1VPS37A CL E G H137492319199ORPHA118824928609927
HP:0002169HP:0011448Ankle clonus1VPS37A CL E G H137492319199ORPHA117324928609927
HP:0002169HP:0011449Knee clonus1VPS37A CL E G H137492319199ORPHA117324928609927
HP:0002169HP:0011728Elbow clonus1VPS37A CL E G H137492319199ORPHA118824928609927
HP:0002169HP:0011728Elbow clonus1VPS37A CL E G H137492319199ORPHA117324928609927
HP:0002169HP:0011448Ankle clonus1VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM118824928609927
HP:0002169HP:0011449Knee clonus1VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM118824928609927
HP:0002169HP:0011448Ankle clonus1VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM117324928609927
HP:0002169HP:0011449Knee clonus1VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM117324928609927
HP:0002169HP:0011728Elbow clonus1VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM118824928609927
HP:0002169HP:0011728Elbow clonus1VPS37A CL E G H137492614898Spastic paraplegia 53, autosomal recessive614898C3539494OMIM117324928609927
HP:0002169HP:0011449Knee clonus1ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1145720761612012
HP:0002169HP:0011448Ankle clonus1ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1145720761612012
HP:0002169HP:0011448Ankle clonus1ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1126420761612012
HP:0002169HP:0011449Knee clonus1ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1126420761612012
HP:0002169HP:0011728Elbow clonus1ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1145720761612012
HP:0002169HP:0011728Elbow clonus1ZFYVE26 CL E G H23503270700Spastic paraplegia 15270700C1849128OMIM1126420761612012
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0002169HP:0002169Clonus0ERLIN1 CL E G H10613401785ORPHA08416947611604
HP:0002169HP:0002169Clonus0ERLIN1 CL E G H10613401785ORPHA05916947611604
HP:0002169HP:0002169Clonus0NDP CL E G H4693649ORPHA02637678300658
HP:0002169HP:0002169Clonus0NDP CL E G H4693649ORPHA02457678300658
HP:0002169HP:0002169Clonus0PTS CL E G H580513Brain malformationC0266449ORPHA01859689612719
HP:0002169HP:0002169Clonus0PTS CL E G H580513Brain malformationC0266449ORPHA01649689612719
HP:0002169HP:0002169Clonus0SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM01087445608465
HP:0002169HP:0002169Clonus0SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM0941445608465
HP:0002169HP:0002169Clonus0TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM013523656607381
HP:0002169HP:0002169Clonus0TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM05223656607381
HP:0002169HP:0002169Clonus0WASHC5 CL E G H9897100989ORPHA049328984610657
HP:0002169HP:0002169Clonus0WASHC5 CL E G H9897100989ORPHA045728984610657
HP:0002169HP:0011448Ankle clonus1ERLIN1 CL E G H10613401785ORPHA08416947611604
HP:0002169HP:0011449Knee clonus1ERLIN1 CL E G H10613401785ORPHA08416947611604
HP:0002169HP:0011448Ankle clonus1ERLIN1 CL E G H10613401785ORPHA05916947611604
HP:0002169HP:0011449Knee clonus1ERLIN1 CL E G H10613401785ORPHA05916947611604
HP:0002169HP:0011728Elbow clonus1ERLIN1 CL E G H10613401785ORPHA08416947611604
HP:0002169HP:0011728Elbow clonus1ERLIN1 CL E G H10613401785ORPHA05916947611604
HP:0002169HP:0011448Ankle clonus1NDP CL E G H4693649ORPHA02637678300658
HP:0002169HP:0011449Knee clonus1NDP CL E G H4693649ORPHA02637678300658
HP:0002169HP:0011448Ankle clonus1NDP CL E G H4693649ORPHA02457678300658
HP:0002169HP:0011449Knee clonus1NDP CL E G H4693649ORPHA02457678300658
HP:0002169HP:0011728Elbow clonus1NDP CL E G H4693649ORPHA02637678300658
HP:0002169HP:0011728Elbow clonus1NDP CL E G H4693649ORPHA02457678300658
HP:0002169HP:0011448Ankle clonus1PTS CL E G H580513Brain malformationC0266449ORPHA01859689612719
HP:0002169HP:0011449Knee clonus1PTS CL E G H580513Brain malformationC0266449ORPHA01859689612719
HP:0002169HP:0011448Ankle clonus1PTS CL E G H580513Brain malformationC0266449ORPHA01649689612719
HP:0002169HP:0011449Knee clonus1PTS CL E G H580513Brain malformationC0266449ORPHA01649689612719
HP:0002169HP:0011728Elbow clonus1PTS CL E G H580513Brain malformationC0266449ORPHA01859689612719
HP:0002169HP:0011728Elbow clonus1PTS CL E G H580513Brain malformationC0266449ORPHA01649689612719
HP:0002169HP:0011448Ankle clonus1SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM01087445608465
HP:0002169HP:0011449Knee clonus1SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM01087445608465
HP:0002169HP:0011448Ankle clonus1SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM0941445608465
HP:0002169HP:0011449Knee clonus1SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM0941445608465
HP:0002169HP:0011728Elbow clonus1SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM01087445608465
HP:0002169HP:0011728Elbow clonus1SETX CL E G H23064602433Amyotrophic lateral sclerosis type 4602433C1865409OMIM0941445608465
HP:0002169HP:0011448Ankle clonus1TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM013523656607381
HP:0002169HP:0011449Knee clonus1TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM013523656607381
HP:0002169HP:0011448Ankle clonus1TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM05223656607381
HP:0002169HP:0011449Knee clonus1TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM05223656607381
HP:0002169HP:0011728Elbow clonus1TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM013523656607381
HP:0002169HP:0011728Elbow clonus1TIMM50 CL E G H926096176983-METHYLGLUTACONIC ACIDURIA, TYPE IX617698C4540171OMIM05223656607381
HP:0002169HP:0011448Ankle clonus1WASHC5 CL E G H9897100989ORPHA049328984610657
HP:0002169HP:0011449Knee clonus1WASHC5 CL E G H9897100989ORPHA049328984610657
HP:0002169HP:0011448Ankle clonus1WASHC5 CL E G H9897100989ORPHA045728984610657
HP:0002169HP:0011449Knee clonus1WASHC5 CL E G H9897100989ORPHA045728984610657
HP:0002169HP:0011728Elbow clonus1WASHC5 CL E G H9897100989ORPHA049328984610657
HP:0002169HP:0011728Elbow clonus1WASHC5 CL E G H9897100989ORPHA045728984610657


Genes (87) :ABCB7 ADGRG1 AMPD2 ANO10 ATL1 ATP6AP2 BRAT1 C12ORF65 C12orf65 CAPN1 CAV1 CCT5 COX1 COX2 COX3 CYP7B1 ERLIN1 FA2H GBA2 HIKESHI HTT KCNT1 KIF1A KIF1C KIF5A MED17 MT-CO1 MT-CO2 MT-CO3 MT-ND1 MT-ND4 MT-ND5 MT-ND6 MT-TF MT-TH MT-TL1 MT-TQ MT-TS1 MT-TS2 MT-TW ND1 ND4 ND5 ND6 NDP NIPA1 OCRL OSTM1 PC PIGT PLPBP PRUNE1 PTS RAB18 REEP1 RTN2 SAMD9L SEPSECS SETX SLC16A2 SLC25A15 SLC33A1 SLC39A14 SLC52A3 SLC6A9 SPART SPAST SPG11 STUB1 TANGO2 TIMM50 TRAK1 TRNF TRNH TRNL1 TRNQ TRNS1 TRNS2 TRNW TSEN2 UCHL1 UFC1 USP8 VPS37A WASHC5 ZFYVE26 ZFYVE27

Diseases (66) :301310 615809 614498 615035 606721 139578 256840 550 401785 615681 616881 614959 397946 613668 649 600363 534 259720 266150 617290 617481 13 100993 613811 602433 300523 238970 171863 617301 616878 617698 618201 612389 618076 401795 319199 614898 100989 270700 606854 284289 100984 363654 488594 100986 171629 612319 614409 617435 610357 604187 615398 614222 610250 604805 159550 617013 211530 101000 275900 100985 604360 412057 615768 615491 610244
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.