Human Phenotype Ontology 
Grandparent Node:
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Abnormality of skin adnexa morphology (HP:0011138)help
Parent Node:
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Abnormality of the nail (HP:0001597)help
..Starting node
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Thin nail (HP:0001816)help
Term ID: 1816
Name: Thin nail
Synonym: Thin nail; Thin nails
Definition: Nail that appears thin when viewed on end.
Comments:
Reference: HP:0001816
Genes and Diseases:
 
       Child Nodes:
........expandThin fingernail (HP:0012742) help
........expandThin toenail (HP:0012746) help

 Sister Nodes: 
..expandAbnormal fingernail morphology (HP:0001231) help
..expandAbnormal nail growth (HP:0030807) help
..expandAbnormal toenail morphology (HP:0008388) help
..expandAbnormality of nail color (HP:0100643) help
..expandAbnormality of the periungual region (HP:0100803) help
..expandAbnormality of the subungual region (HP:0009723) help
..expandAbsent lunula (HP:0030805) help
..expandAplasia/Hypoplasia of the nails (HP:0008386) help
..expandBeaked nails (HP:0030817) help
..expandChronic monilial nail infection (HP:0008396) help
..expandFragile nails (HP:0001808) help
..expandIngrown nail (HP:0012710) help
..expandNail bed hemorrhage (HP:0030254) help
..expandNail bed telangiectasia (HP:0001232) help
..expandNail dysplasia (HP:0002164) help
..expandNail dystrophy (HP:0008404) help
..expandNeoplasm of the nail (HP:0100826) help
..expandOnychogryposis (HP:0001805) help
..expandOnycholysis (HP:0001806) help
..expandPterygium of nails (HP:0002165) help
..expandPyramidal skinfold extending from the base to the top of the nails (HP:0009758) help
..expandRagged cuticle (HP:0030808) help
..expandRecurrent loss of toenails and fingernails (HP:0008390) help
..expandSki jump nail (HP:0030819) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0001816HP:0001816Thin nail0EED CL E G H87263447ORPHA1863188605984
HP:0001816HP:0001816Thin nail0EED CL E G H87263447ORPHA1803188605984
HP:0001816HP:0001816Thin nail0EED CL E G H8726617561Cohen-Gibson syndrome617561C4479654OMIM1803188605984
HP:0001816HP:0001816Thin nail0EED CL E G H8726617561Cohen-Gibson syndrome617561C4479654OMIM1863188605984
HP:0001816HP:0001816Thin nail0EZH2 CL E G H21463447ORPHA13293527601573
HP:0001816HP:0001816Thin nail0EZH2 CL E G H21463447ORPHA13643527601573
HP:0001816HP:0001816Thin nail0EZH2 CL E G H2146277590Weaver syndrome277590C0265210OMIM13643527601573
HP:0001816HP:0001816Thin nail0EZH2 CL E G H2146277590Weaver syndrome277590C0265210OMIM13293527601573
HP:0001816HP:0001816Thin nail0HRAS CL E G H3265218040Costello syndrome218040C0587248OMIM14115173190020
HP:0001816HP:0001816Thin nail0HRAS CL E G H3265218040Costello syndrome218040C0587248OMIM14675173190020
HP:0001816HP:0001816Thin nail0IFT122 CL E G H55764218330Cranioectodermal dysplasia 1218330C0432235OMIM139113556606045
HP:0001816HP:0001816Thin nail0IFT122 CL E G H55764218330Cranioectodermal dysplasia 1218330C0432235OMIM131713556606045
HP:0001816HP:0001816Thin nail0LMNA CL E G H4000740Aortic arch interruptionORPHA114866636150330
HP:0001816HP:0001816Thin nail0LMNA CL E G H4000740Aortic arch interruptionORPHA113476636150330
HP:0001816HP:0001816Thin nail0NSD1 CL E G H643243447ORPHA1124014234606681
HP:0001816HP:0001816Thin nail0NSD1 CL E G H643243447ORPHA1115414234606681
HP:0001816HP:0001816Thin nail0SUZ12 CL E G H235123447ORPHA18817101606245
HP:0001816HP:0001816Thin nail0SUZ12 CL E G H235123447ORPHA19317101606245
HP:0001816HP:0001816Thin nail0TRPS1 CL E G H7227190350Trichorhinophalangeal dysplasia type I190350C0432233OMIM133612340604386
HP:0001816HP:0001816Thin nail0TRPS1 CL E G H7227190350Trichorhinophalangeal dysplasia type I190350C0432233OMIM127012340604386
HP:0001816HP:0001816Thin nail0WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM129113829606268
HP:0001816HP:0001816Thin nail0WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM130913829606268
HP:0001816HP:0001816Thin nail0ZMPSTE24 CL E G H10269740Aortic arch interruptionORPHA114912877606480
HP:0001816HP:0001816Thin nail0ZMPSTE24 CL E G H10269740Aortic arch interruptionORPHA116712877606480
HP:0001816HP:0012746Thin toenail1EED CL E G H87263447ORPHA1803188605984
HP:0001816HP:0012742Thin fingernail1EED CL E G H87263447ORPHA1863188605984
HP:0001816HP:0012742Thin fingernail1EED CL E G H87263447ORPHA1803188605984
HP:0001816HP:0012746Thin toenail1EED CL E G H87263447ORPHA1863188605984
HP:0001816HP:0012742Thin fingernail1EED CL E G H8726617561Cohen-Gibson syndrome617561C4479654OMIM1803188605984
HP:0001816HP:0012746Thin toenail1EED CL E G H8726617561Cohen-Gibson syndrome617561C4479654OMIM1863188605984
HP:0001816HP:0012746Thin toenail1EED CL E G H8726617561Cohen-Gibson syndrome617561C4479654OMIM1803188605984
HP:0001816HP:0012742Thin fingernail1EED CL E G H8726617561Cohen-Gibson syndrome617561C4479654OMIM1863188605984
HP:0001816HP:0012742Thin fingernail1EZH2 CL E G H21463447ORPHA13293527601573
HP:0001816HP:0012746Thin toenail1EZH2 CL E G H21463447ORPHA13643527601573
HP:0001816HP:0012746Thin toenail1EZH2 CL E G H21463447ORPHA13293527601573
HP:0001816HP:0012742Thin fingernail1EZH2 CL E G H21463447ORPHA13643527601573
HP:0001816HP:0012746Thin toenail1EZH2 CL E G H2146277590Weaver syndrome277590C0265210OMIM13293527601573
HP:0001816HP:0012742Thin fingernail1EZH2 CL E G H2146277590Weaver syndrome277590C0265210OMIM13643527601573
HP:0001816HP:0012742Thin fingernail1EZH2 CL E G H2146277590Weaver syndrome277590C0265210OMIM13293527601573
HP:0001816HP:0012746Thin toenail1EZH2 CL E G H2146277590Weaver syndrome277590C0265210OMIM13643527601573
HP:0001816HP:0012742Thin fingernail1HRAS CL E G H3265218040Costello syndrome218040C0587248OMIM14115173190020
HP:0001816HP:0012746Thin toenail1HRAS CL E G H3265218040Costello syndrome218040C0587248OMIM14675173190020
HP:0001816HP:0012746Thin toenail1HRAS CL E G H3265218040Costello syndrome218040C0587248OMIM14115173190020
HP:0001816HP:0012742Thin fingernail1HRAS CL E G H3265218040Costello syndrome218040C0587248OMIM14675173190020
HP:0001816HP:0012746Thin toenail1IFT122 CL E G H55764218330Cranioectodermal dysplasia 1218330C0432235OMIM131713556606045
HP:0001816HP:0012742Thin fingernail1IFT122 CL E G H55764218330Cranioectodermal dysplasia 1218330C0432235OMIM139113556606045
HP:0001816HP:0012742Thin fingernail1IFT122 CL E G H55764218330Cranioectodermal dysplasia 1218330C0432235OMIM131713556606045
HP:0001816HP:0012746Thin toenail1IFT122 CL E G H55764218330Cranioectodermal dysplasia 1218330C0432235OMIM139113556606045
HP:0001816HP:0012746Thin toenail1LMNA CL E G H4000740Aortic arch interruptionORPHA113476636150330
HP:0001816HP:0012742Thin fingernail1LMNA CL E G H4000740Aortic arch interruptionORPHA114866636150330
HP:0001816HP:0012742Thin fingernail1LMNA CL E G H4000740Aortic arch interruptionORPHA113476636150330
HP:0001816HP:0012746Thin toenail1LMNA CL E G H4000740Aortic arch interruptionORPHA114866636150330
HP:0001816HP:0012746Thin toenail1NSD1 CL E G H643243447ORPHA1115414234606681
HP:0001816HP:0012742Thin fingernail1NSD1 CL E G H643243447ORPHA1124014234606681
HP:0001816HP:0012742Thin fingernail1NSD1 CL E G H643243447ORPHA1115414234606681
HP:0001816HP:0012746Thin toenail1NSD1 CL E G H643243447ORPHA1124014234606681
HP:0001816HP:0012742Thin fingernail1SUZ12 CL E G H235123447ORPHA18817101606245
HP:0001816HP:0012746Thin toenail1SUZ12 CL E G H235123447ORPHA19317101606245
HP:0001816HP:0012746Thin toenail1SUZ12 CL E G H235123447ORPHA18817101606245
HP:0001816HP:0012742Thin fingernail1SUZ12 CL E G H235123447ORPHA19317101606245
HP:0001816HP:0012746Thin toenail1TRPS1 CL E G H7227190350Trichorhinophalangeal dysplasia type I190350C0432233OMIM127012340604386
HP:0001816HP:0012742Thin fingernail1TRPS1 CL E G H7227190350Trichorhinophalangeal dysplasia type I190350C0432233OMIM133612340604386
HP:0001816HP:0012742Thin fingernail1TRPS1 CL E G H7227190350Trichorhinophalangeal dysplasia type I190350C0432233OMIM127012340604386
HP:0001816HP:0012746Thin toenail1TRPS1 CL E G H7227190350Trichorhinophalangeal dysplasia type I190350C0432233OMIM133612340604386
HP:0001816HP:0012742Thin fingernail1WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM129113829606268
HP:0001816HP:0012746Thin toenail1WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM130913829606268
HP:0001816HP:0012746Thin toenail1WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM129113829606268
HP:0001816HP:0012742Thin fingernail1WNT10A CL E G H80326224750Schopf-Schulz-Passarge syndrome224750C1857069OMIM130913829606268
HP:0001816HP:0012742Thin fingernail1ZMPSTE24 CL E G H10269740Aortic arch interruptionORPHA114912877606480
HP:0001816HP:0012746Thin toenail1ZMPSTE24 CL E G H10269740Aortic arch interruptionORPHA116712877606480
HP:0001816HP:0012746Thin toenail1ZMPSTE24 CL E G H10269740Aortic arch interruptionORPHA114912877606480
HP:0001816HP:0012742Thin fingernail1ZMPSTE24 CL E G H10269740Aortic arch interruptionORPHA116712877606480
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0001816HP:0001816Thin nail0ALOX12B CL E G H242242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM0291430603741
HP:0001816HP:0001816Thin nail0ALOX12B CL E G H242242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM0285430603741
HP:0001816HP:0001816Thin nail0ALOXE3 CL E G H59344242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM020213743607206
HP:0001816HP:0001816Thin nail0ALOXE3 CL E G H59344242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM020913743607206
HP:0001816HP:0012746Thin toenail1ALOX12B CL E G H242242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM0285430603741
HP:0001816HP:0012742Thin fingernail1ALOX12B CL E G H242242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM0291430603741
HP:0001816HP:0012742Thin fingernail1ALOX12B CL E G H242242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM0285430603741
HP:0001816HP:0012746Thin toenail1ALOX12B CL E G H242242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM0291430603741
HP:0001816HP:0012742Thin fingernail1ALOXE3 CL E G H59344242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM020213743607206
HP:0001816HP:0012746Thin toenail1ALOXE3 CL E G H59344242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM020913743607206
HP:0001816HP:0012746Thin toenail1ALOXE3 CL E G H59344242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM020213743607206
HP:0001816HP:0012742Thin fingernail1ALOXE3 CL E G H59344242100Autosomal recessive congenital ichthyosis 2242100C1855792OMIM020913743607206


Genes (15) :ALOX12B ALOXE3 EED EZH2 HRAS IFT122 LMNA MBTPS2 MECP2 MSX1 NSD1 SUZ12 TRPS1 WNT10A ZMPSTE24

Diseases (12) :242100 3447 617561 277590 218040 218330 740 190350 224750 2273 778 2228
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.