Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of the plantar skin of foot (HP:0100872)

Grandparent Node:
Hyperkeratosis (HP:0000962)

Parent Node:
Palmar hyperkeratosis (HP:0010765)

Parent Node:
Plantar hyperkeratosis (HP:0007556)

..Starting node
..Palmoplantar hyperkeratosis (HP:0000972)

Term ID:

972

Name:

Palmoplantar hyperkeratosis

Synonym:

Hyperkeratosis of palms and soles; Hyperkeratosis of the palms and soles; Palmoplantar keratoses; Palmoplantar keratosis; Thick palms and soles; Thickened palms and soles; Thickening of the outer layer of the skin of the palms and soles

Definition:

Abnormal thickening of the skin localized to the palm of the hand and the sole of the foot.

Comments:

Reference:

HP:0000972

Genes and Diseases:

Child Nodes:

........

Diffuse palmoplantar hyperkeratosis (HP:0007447)

........

Focal friction-related palmoplantar hyperkeratosis (HP:0007497)

........

Punctate palmoplantar hyperkeratosis (HP:0007530)

........

Congenital palmoplantar keratosis (HP:0007545)

........

Palmoplantar keratosis with erythema and scale (HP:0007548)

........

Congenital symmetrical palmoplantar keratosis (HP:0007553)

........

Spinous keratoses of palms and soles (HP:0007613)

Sister Nodes:

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	DiseaseId	DiseaseName	DiseaseMIM	ConceptID	Source	Typical association	ClinVar variants	HGNC ID	GeneMIM
HPO disease - gene - phenotype typical associations:
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	AAAS CL E G H	8086	231550	Glucocorticoid deficiency with achalasia	231550	C0271742	OMIM	1	187	13666	605378
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	AKT1 CL E G H	207	615109	Cowden syndrome 6	615109	C3554519	OMIM	1	634	391	164730
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	COG6 CL E G H	57511	615328	Shaheen syndrome	615328	C3809160	OMIM	1	315	18621	606977
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	CTSC CL E G H	1075	678				ORPHA	1	268	2528	602365
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	CTSC CL E G H	1075	245000	Papillon-Lefèvre syndrome	245000	C0030360	OMIM	1	268	2528	602365
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	FERMT1 CL E G H	55612	173650	Kindler's syndrome	173650	C0406557	OMIM	1	421	15889	607900
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	GJA1 CL E G H	2697	1010				ORPHA	1	221	4274	121014
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	GJA1 CL E G H	2697	104100	Alopecia congenita keratosis palmoplantaris	104100	C1863093	OMIM	1	221	4274	121014
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	GJB2 CL E G H	2706	148350	Keratoderma palmoplantar deafness	148350	C1835672	OMIM	1	516	4284	121011
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	GJB6 CL E G H	10804	129500	Hidrotic ectodermal dysplasia syndrome	129500	C0162361	OMIM	1	235	4288	604418
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	HPGD CL E G H	3248	259100	Pachydermoperiostosis syndrome	259100	C0029411	OMIM	1	196	5154	601688
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KDSR CL E G H	2531	617526	Erythrokeratodermia variabilis et progressiva 4	617526	C4479620	OMIM	1	99	4021	136440
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	155	6412	139350
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT1 CL E G H	3848	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	155	6412	139350
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT1 CL E G H	3848	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	155	6412	139350
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT10 CL E G H	3858	113800	Bullous ichthyosiform erythroderma	113800	C0079153	OMIM	1	127	6413	148080
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	609165	Erythroderma, ichthyosiform, congenital reticular	609165	C1836681	OMIM	1	127	6413	148080
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT10 CL E G H	3858	607602	Ichthyosis, cyclic, with epidermolytic hyperkeratosis	607602	C1843463	OMIM	1	127	6413	148080
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT14 CL E G H	3861	125595	Dermatopathia pigmentosa reticularis	125595	C0406778	OMIM	1	167	6416	148066
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT14 CL E G H	3861	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	167	6416	148066
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT14 CL E G H	3861	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	167	6416	148066
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT16 CL E G H	3868	167200	Pachyonychia congenita 1	167200	C1706595	OMIM	1	72	6423	148067
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT17 CL E G H	3872	167210	Pachyonychia congenita 2	167210	C1721007	OMIM	1	69	6427	148069
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT5 CL E G H	3852	131760	Epidermolysis bullosa herpetiformis, Dowling-Meara	131760	C0079295	OMIM	1	258	6442	148040
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT5 CL E G H	3852	131900	Epidermolysis bullosa simplex, Koebner type	131900	C0079299	OMIM	1	258	6442	148040
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT83 CL E G H	3889	617756	ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA 5	617756	C4540331	OMIM	1	125	6460	602765
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	KRT9 CL E G H	3857	144200	Localized epidermolytic hyperkeratosis	144200	C1721006	OMIM	1	137	6447	607606
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	MBTPS2 CL E G H	51360	300918	Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked	300918	C3806745	OMIM	1	248	15455	300294
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	NECTIN1 CL E G H	5818	225060	Cleft lip/palate-ectodermal dysplasia syndrome	225060	C2931488	OMIM	1	208	9706	600644
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	PIGL CL E G H	9487	280000	Zunich neuroectodermal syndrome	280000	C1848392	OMIM	1	127	8966	605947
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	PIK3CA CL E G H	5290	615108	Cowden syndrome 5	615108	C3554518	OMIM	1	975	8975	171834
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	PLEC CL E G H	5339	226670	Epidermolysa bullosa simplex and limb girdle muscular dystrophy	226670	C2931072	OMIM	1	4152	9069	601282
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	PTEN CL E G H	5728	158350	Cowden syndrome 1	158350	CN072330	OMIM	1	2750	9588	601728
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	SDR9C7 CL E G H	121214	617574	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 13	617574	C4539772	OMIM	1	36	29958	609769
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0000972	Palmoplantar hyperkeratosis	0	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	NECTIN1 CL E G H	5818	3253	Limb dystonia			ORPHA	0	208	9706	600644
HP:0000972	HP:0007447	Diffuse palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0000982	Palmoplantar keratoderma	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007613	Spinous keratoses of palms and soles	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007553	Congenital symmetrical palmoplantar keratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007404	Nonepidermolytic palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007530	Punctate palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007545	Congenital palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007465	Honeycomb palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0005588	Patchy palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007497	Focal friction-related palmoplantar hyperkeratosis	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195
HP:0000972	HP:0007548	Palmoplantar keratosis with erythema and scale	1	TGM1 CL E G H	7051	242300	Autosomal recessive congenital ichthyosis 1	242300	C3536797	OMIM	0	620	11777	190195

Genes (145) :AAAS AAGAB ABCA12 ABCC9 ACTC1 ACTN2 AKT1 ALOX12B ALOXE3 ANKRD1 ATP2A2 BAG3 BRAF CARD14 CAST CD28 CERS3 COG6 COL14A1 COL17A1 CRYAB CSRP3 CSTA CTC1 CTLA4 CTSC CYP4F22 DES DKC1 DMD DOLK DSC2 DSG1 DSG2 DSP ENPP1 FERMT1 FGFR2 FHL2 FKTN GATAD1 GJA1 GJB2 GJB3 GJB4 GJB6 GMPPA HPGD ITGB4 JUP KANK2 KDSR KLLN KRAS KRT1 KRT10 KRT14 KRT16 KRT17 KRT2 KRT5 KRT6A KRT6B KRT6C KRT83 KRT9 LAMA3 LAMA4 LAMB3 LAMC2 LDB3 LEMD3 LOR MAP2K1 MAP2K2 MBTPS2 MCOLN1 MYBPC3 MYH6 MYH7 MYPN NEBL NECTIN1 NEXN NHP2 NIPAL4 NLRP1 NOP10 PARN PEPD PIGL PIK3CA PKP1 PLEC PLN PNPLA1 POMP PPCS PRDM16 PSEN1 PSEN2 PTEN RAF1 RBM20 RECQL4 RHBDF2 RSPO1 RTEL1 SCN5A SDHA SDHB SDHC SDHD SDR9C7 SEC23B SERPINB7 SGCD SLCO2A1 SLURP1 SMARCAD1 SNAP29 TAF1A TAT TAZ TCAP TERC TERT TGM1 TINF2 TMPO TNFRSF1B TNNC1 TNNI3 TNNT2 TP63 TPM1 TRAPPC11 TRNS1 TRPV3 TTN TXNRD2 USB1 VCL WNT10A WRAP53

Diseases (125) :231550 615109 615328 678 245000 173650 1010 104100 148350 129500 259100 617526 113800 607602 144200 609165 125595 131760 131900 167200 167210 617756 300918 225060 3253 280000 615108 226670 158350 617574 242300 869 79501 148600 79394 601277 154 201 242100 606545 218 1340 2897 173200 616295 3162 79402 607936 1775 245010 604777 610476 50942 615508 148700 65282 615821 605676 612908 607655 615522 2908 1555 617525 2710 317 2698 494 477 2202 602540 124500 133200 617524 189 2796 34217 601214 616099 316 312 2199 607654 600962 89838 79400 79399 79397 79396 161000 2309 613000 455 131960 615726 615728 615735 1306 79395 659 308800 578 612281 615225 742 158668 615024 281201 601952 221016 2198 148500 85112 610644 140966 248300 384 609528 28378 1071 106260 614594 616400 50944 224750

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.

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