Term ID: |
8866 |
Name: |
Failure to thrive secondary to recurrent infections |
Synonym: |
Faltering weight secondary to recurrent infections; Weight faltering secondary to recurrent infections |
Definition: |
Insufficient weight gain or inappropriate weight loss for a child, that is attributed to an endogenous recurrent infections. |
Comments: |
|
Reference: |
HP:0008866 |
Genes and Diseases: | |
Child Nodes: |
Sister Nodes: |
..Recurrent abscess formation (HP:0002722)
|
..Recurrent bacterial infections (HP:0002718)
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..Recurrent ear infections (HP:0410018)
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..Recurrent fungal infections (HP:0002841)
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..Recurrent infection of the gastrointestinal tract (HP:0004798)
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..Recurrent infections in infancy and early childhood (HP:0005437)
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..Recurrent infections of the middle ear (HP:0040268)
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..Recurrent opportunistic infections (HP:0005390)
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..Recurrent otitis media (HP:0000403)
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..Recurrent parasitic infections (HP:0030885)
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..Recurrent protozoan infections (HP:0005386)
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..Recurrent respiratory infections (HP:0002205)
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..Recurrent urinary tract infections (HP:0000010)
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..Recurrent viral infections (HP:0004429)
|
Input | HPO ID | HPO term | Distance | Gene | Gene id entrez | HGNC ID | DiseaseId | DiseaseName | Frequency | Onset | HGMD variants | ClinVar variants |
---|
HPO disease - gene - phenotype typical associations: | HPO disease - gene - phenotype less frequent non-typical associations: | HP:0008866 | HP:0008866 | Failure to thrive secondary to recurrent infections | 0 | CD247 CL E G H | 919 | 1677 | ORPHA:169160 | T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta | HP:0040282 - Frequent | | | 8 | | | HP:0008866 | HP:0008866 | Failure to thrive secondary to recurrent infections | 0 | CD3D CL E G H | 915 | 1673 | ORPHA:169160 | T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta | HP:0040282 - Frequent | | | 18 | | | HP:0008866 | HP:0008866 | Failure to thrive secondary to recurrent infections | 0 | CD3E CL E G H | 916 | 1674 | ORPHA:169160 | T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta | HP:0040282 - Frequent | | | 24 | | | HP:0008866 | HP:0008866 | Failure to thrive secondary to recurrent infections | 0 | IL7R CL E G H | 3575 | 6024 | OMIM:608971 | Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, NK cell-positive | . | | | 94 | | | HP:0008866 | HP:0008866 | Failure to thrive secondary to recurrent infections | 0 | RAG1 CL E G H | 5896 | 9831 | OMIM:601457 | Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive | . | | | 127 | | | HP:0008866 | HP:0008866 | Failure to thrive secondary to recurrent infections | 0 | RAG2 CL E G H | 5897 | 9832 | OMIM:601457 | Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive | . | | | 50 | | |
Genes (6) :CD247 CD3D CD3E IL7R RAG1 RAG2
Diseases (3) :ORPHA:169160 OMIM:608971 OMIM:601457 |
Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.
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