Human Phenotype Ontology 
Grandparent Node:
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Behavioral abnormality (HP:0000708)help
Parent Node:
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Obsessive-compulsive behavior (HP:0000722)help
..Starting node
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Obsessive-compulsive trait (HP:0008770)help
Term ID: 8770
Name: Obsessive-compulsive trait
Synonym: Obsessive-compulsive trait; Obsessive-compulsive traits
Definition: The presence of one or more obsessive-compulsive personality traits. Obsessions refer to persistent intrusive thoughts, and compulsions to intrusive behaviors, which the affected person experiences as involuntary, senseless, or repugnant.
Comments:
Reference: HP:0008770
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandCollectionism (HP:0030212) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0008770HP:0008770Obsessive-compulsive trait0ADGRV1 CL E G H8405917416ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare530
HP:0008770HP:0008770Obsessive-compulsive trait0ASH1L CL E G H5587019088OMIM:617796Mental retardation, autosomal dominant 521
HP:0008770HP:0008770Obsessive-compulsive trait0CLN5 CL E G H12032076ORPHA:228360CLN5 diseaseHP:0040283 - Occasional141
HP:0008770HP:0008770Obsessive-compulsive trait0DMPK CL E G H17602933OMIM:160900Myotonic dystrophy 1.152
HP:0008770HP:0008770Obsessive-compulsive trait0ELN CL E G H20063327OMIM:194050Williams-Beuren syndrome.172
HP:0008770HP:0008770Obsessive-compulsive trait0FMO3 CL E G H23283771ORPHA:468726Severe primary trimethylaminuriaHP:0040283 - Occasional55
HP:0008770HP:0008770Obsessive-compulsive trait0FMR1 CL E G H23323775OMIM:300623Fragile X tremor/ataxia syndrome30
HP:0008770HP:0008770Obsessive-compulsive trait0GABRA1 CL E G H25544075ORPHA:33069Dravet syndromeHP:0040282 - Frequent134
HP:0008770HP:0008770Obsessive-compulsive trait0GABRD CL E G H25634084ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare10
HP:0008770HP:0008770Obsessive-compulsive trait0GABRG2 CL E G H25664087ORPHA:33069Dravet syndromeHP:0040282 - Frequent139
HP:0008770HP:0008770Obsessive-compulsive trait0GABRG2 CL E G H25664087ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare139
HP:0008770HP:0008770Obsessive-compulsive trait0GATAD2B CL E G H5745930778ORPHA:363686Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndromeHP:0040283 - Occasional33
HP:0008770HP:0008770Obsessive-compulsive trait0HCN1 CL E G H3489804845ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare54
HP:0008770HP:0008770Obsessive-compulsive trait0MAGEL2 CL E G H545516814ORPHA:177901Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1HP:0040282 - Frequent63
HP:0008770HP:0008770Obsessive-compulsive trait0MAGEL2 CL E G H545516814ORPHA:177904Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2HP:0040282 - Frequent63
HP:0008770HP:0008770Obsessive-compulsive trait0MLXIPL CL E G H5108512744OMIM:194050Williams-Beuren syndrome.1
HP:0008770HP:0008770Obsessive-compulsive trait0NDN CL E G H46927675ORPHA:177901Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1HP:0040282 - Frequent
HP:0008770HP:0008770Obsessive-compulsive trait0NDN CL E G H46927675ORPHA:177904Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2HP:0040282 - Frequent
HP:0008770HP:0008770Obsessive-compulsive trait0OCA2 CL E G H49488101ORPHA:177901Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1HP:0040282 - Frequent121
HP:0008770HP:0008770Obsessive-compulsive trait0OCA2 CL E G H49488101ORPHA:177904Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2HP:0040282 - Frequent121
HP:0008770HP:0008770Obsessive-compulsive trait0PANK2 CL E G H8002515894OMIM:234200Neurodegeneration with brain iron accumulation 1.55
HP:0008770HP:0008770Obsessive-compulsive trait0PCDH19 CL E G H5752614270ORPHA:33069Dravet syndromeHP:0040282 - Frequent225
HP:0008770HP:0008770Obsessive-compulsive trait0SCN1A CL E G H632310585ORPHA:33069Dravet syndromeHP:0040282 - Frequent1053
HP:0008770HP:0008770Obsessive-compulsive trait0SCN1A CL E G H632310585ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare1053
HP:0008770HP:0008770Obsessive-compulsive trait0SCN1B CL E G H632410586ORPHA:33069Dravet syndromeHP:0040282 - Frequent126
HP:0008770HP:0008770Obsessive-compulsive trait0SCN1B CL E G H632410586ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare126
HP:0008770HP:0008770Obsessive-compulsive trait0SCN2A CL E G H632610588ORPHA:33069Dravet syndromeHP:0040282 - Frequent427
HP:0008770HP:0008770Obsessive-compulsive trait0SCN2A CL E G H632610588ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare427
HP:0008770HP:0008770Obsessive-compulsive trait0SCN9A CL E G H633510597ORPHA:33069Dravet syndromeHP:0040282 - Frequent318
HP:0008770HP:0008770Obsessive-compulsive trait0SCN9A CL E G H633510597ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare318
HP:0008770HP:0008770Obsessive-compulsive trait0SLC45A1 CL E G H5065117939OMIM:617532Intellectual developmental disorder with neuropsychiatric features.2
HP:0008770HP:0008770Obsessive-compulsive trait0SNRPN CL E G H663811164ORPHA:177901Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1HP:0040282 - Frequent37
HP:0008770HP:0008770Obsessive-compulsive trait0SNRPN CL E G H663811164ORPHA:177904Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2HP:0040282 - Frequent37
HP:0008770HP:0008770Obsessive-compulsive trait0STX1B CL E G H11275518539ORPHA:36387Generalized epilepsy with febrile seizures-plusHP:0040284 - Very rare9
HP:0008770HP:0008770Obsessive-compulsive trait0SYNGAP1 CL E G H883111497ORPHA:544254SYNGAP1-related developmental and epileptic encephalopathyHP:0040283 - Occasional108
HP:0008770HP:0008770Obsessive-compulsive trait0TIAM1 CL E G H707411805OMIM:6199082
HP:0008770HP:0008770Obsessive-compulsive trait0TRIO CL E G H720412303OMIM:618825INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 63, WITH MACROCEPHALY; MRD638
HP:0008770HP:0008770Obsessive-compulsive trait0USP7 CL E G H787412630ORPHA:50005516p13.2 microdeletion syndromeHP:0040283 - Occasional2
HP:0008770HP:0008770Obsessive-compulsive trait0YWHAG CL E G H753212852OMIM:617665Epileptic encephalopathy, early infantile, 56.


Genes (30) :ADGRV1 ASH1L CLN5 DMPK ELN FMO3 FMR1 GABRA1 GABRD GABRG2 GATAD2B HCN1 MAGEL2 MLXIPL NDN OCA2 PANK2 PCDH19 SCN1A SCN1B SCN2A SCN9A SLC45A1 SNRPN STX1B SYNGAP1 TIAM1 TRIO USP7 YWHAG

Diseases (18) :ORPHA:36387 OMIM:617796 ORPHA:228360 OMIM:160900 OMIM:194050 ORPHA:468726 OMIM:300623 ORPHA:33069 ORPHA:363686 ORPHA:177901 ORPHA:177904 OMIM:234200 OMIM:617532 ORPHA:544254 OMIM:619908 OMIM:618825 ORPHA:500055 OMIM:617665
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.