Human Phenotype Ontology 
Grandparent Node:
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Abnormal retinal morphology (HP:0000479)help
Parent Node:
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Retinal detachment (HP:0000541)help
..Starting node
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Tractional retinal detachment (HP:0007917)help
Term ID: 7917
Name: Tractional retinal detachment
Synonym:
Definition: A type of retinal detachment arising due to a combination of contracting retinal membranes, abnormal vitreoretinal adhesions, and vitreous changes. It is usually seen in the context of diseases that induce a fibrovascular response, e.g. diabetes.
Comments:
Reference: HP:0007917
Genes and Diseases:
 
       Child Nodes:
........expandPeripheral tractional retinal detachment (HP:0007643) help

 Sister Nodes: 
..expandExudative retinal detachment (HP:0012231) help
..expandPeripheral retinal detachment (HP:0007929) help
..expandRetinal nonattachment (HP:0007899) help
..expandRhegmatogenous retinal detachment (HP:0012230) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007917HP:0007917Tractional retinal detachment0ATOH7 CL E G H22020213907ORPHA:91495Persistent hyperplastic primary vitreous4
HP:0007917HP:0007917Tractional retinal detachment0CTNNB1 CL E G H14992514ORPHA:891Familial exudative vitreoretinopathyHP:0040282 - Frequent88
HP:0007917HP:0007917Tractional retinal detachment0FZD4 CL E G H83224042ORPHA:891Familial exudative vitreoretinopathyHP:0040282 - Frequent109
HP:0007917HP:0007917Tractional retinal detachment0FZD4 CL E G H83224042ORPHA:91495Persistent hyperplastic primary vitreous109
HP:0007917HP:0007917Tractional retinal detachment0FZD4 CL E G H83224042ORPHA:90050Retinopathy of prematurityHP:0040283 - Occasional109
HP:0007917HP:0007917Tractional retinal detachment0LRP5 CL E G H40416697OMIM:601813Exudative vitreoretinopathy 4.125
HP:0007917HP:0007917Tractional retinal detachment0LRP5 CL E G H40416697ORPHA:891Familial exudative vitreoretinopathyHP:0040282 - Frequent125
HP:0007917HP:0007917Tractional retinal detachment0LRP5 CL E G H40416697ORPHA:90050Retinopathy of prematurityHP:0040283 - Occasional125
HP:0007917HP:0007917Tractional retinal detachment0NDP CL E G H46937678ORPHA:891Familial exudative vitreoretinopathyHP:0040282 - Frequent39
HP:0007917HP:0007917Tractional retinal detachment0NDP CL E G H46937678ORPHA:91495Persistent hyperplastic primary vitreous39
HP:0007917HP:0007917Tractional retinal detachment0NDP CL E G H46937678ORPHA:90050Retinopathy of prematurityHP:0040283 - Occasional39
HP:0007917HP:0007917Tractional retinal detachment0TSPAN12 CL E G H2355421641OMIM:613310Exudative vitreoretinopathy 5HP:0040283 - Occasional39
HP:0007917HP:0007917Tractional retinal detachment0TSPAN12 CL E G H2355421641ORPHA:891Familial exudative vitreoretinopathyHP:0040282 - Frequent39
HP:0007917HP:0007917Tractional retinal detachment0VCAN CL E G H14622464OMIM:143200Wagner vitreoretinopathy180
HP:0007917HP:0007917Tractional retinal detachment0ZNF408 CL E G H7979720041ORPHA:891Familial exudative vitreoretinopathyHP:0040282 - Frequent14
HP:0007917HP:0007643Peripheral tractional retinal detachment1VCAN CL E G H14622464OMIM:143200Wagner vitreoretinopathy.180


Genes (8) :ATOH7 CTNNB1 FZD4 LRP5 NDP TSPAN12 VCAN ZNF408

Diseases (6) :ORPHA:91495 ORPHA:891 ORPHA:90050 OMIM:601813 OMIM:613310 OMIM:143200
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.