Human Phenotype Ontology 
Grandparent Node:
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Abnormal anterior eye segment morphology (HP:0004328)help
Parent Node:
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Abnormal anterior chamber morphology (HP:0000593)help
..Starting node
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Anterior chamber synechiae (HP:0007833)help
Term ID: 7833
Name: Anterior chamber synechiae
Synonym:
Definition:
Comments:
Reference: HP:0007833
Genes and Diseases:
 
       Child Nodes:
........expandAnterior synechiae of the anterior chamber (HP:0011483) help
........expandPosterior synechiae of the anterior chamber (HP:0011484) help

 Sister Nodes: 
..expandAbnormal trabecular meshwork morphology (HP:0012630) help
..expandAbsent anterior chamber of the eye (HP:0008037) help
..expandAnterior chamber cells (HP:0025560) help
..expandAnterior chamber cyst (HP:0025311) help
..expandAnterior chamber flare (HP:0031616) help
..expandAnterior chamber inflammatory cells (HP:0031701) help
..expandAnterior chamber red blood cells (HP:0031702) help
..expandCorneolenticular adhesion (HP:0011485) help
..expandDeep anterior chamber (HP:0007765) help
..expandHypopyon (HP:0031615) help
..expandOcular anterior segment dysgenesis (HP:0007700) help
..expandShallow anterior chamber (HP:0000594) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007833HP:0007833Anterior chamber synechiae0ANKRD55 CL E G H7972225681ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional
HP:0007833HP:0007833Anterior chamber synechiae0ASPH CL E G H444757OMIM:601552Facial dysmorphism, lens dislocation, anterior segment abnormalities, and spontaneous filtering blebs4
HP:0007833HP:0007833Anterior chamber synechiae0ATOH7 CL E G H22020213907OMIM:221900Persistent hyperplastic primary vitreous, autosomal recessive4
HP:0007833HP:0007833Anterior chamber synechiae0B3GLCT CL E G H14517320207ORPHA:709Peters plus syndromeHP:0040281 - Very frequent36
HP:0007833HP:0007833Anterior chamber synechiae0CD247 CL E G H9191677ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional8
HP:0007833HP:0007833Anterior chamber synechiae0COL18A1 CL E G H807812195OMIM:618880GLAUCOMA, PRIMARY CLOSED-ANGLE; GLCC177
HP:0007833HP:0007833Anterior chamber synechiae0COL8A2 CL E G H12962216ORPHA:98973Posterior polymorphous corneal dystrophy3
HP:0007833HP:0007833Anterior chamber synechiae0CYP1B1 CL E G H15452597OMIM:617315ANTERIOR SEGMENT DYSGENESIS 6; ASGD6101
HP:0007833HP:0007833Anterior chamber synechiae0CYP1B1 CL E G H15452597ORPHA:708Peters anomaly101
HP:0007833HP:0007833Anterior chamber synechiae0FOXC1 CL E G H22963800OMIM:602482Axenfeld-rieger syndrome, type 363
HP:0007833HP:0007833Anterior chamber synechiae0FOXC1 CL E G H22963800ORPHA:708Peters anomaly63
HP:0007833HP:0007833Anterior chamber synechiae0FOXE3 CL E G H23013808OMIM:610256Anterior segment dysgenesis 223
HP:0007833HP:0007833Anterior chamber synechiae0FOXE3 CL E G H23013808ORPHA:708Peters anomaly23
HP:0007833HP:0007833Anterior chamber synechiae0GRHL2 CL E G H799772799ORPHA:98973Posterior polymorphous corneal dystrophy33
HP:0007833HP:0007833Anterior chamber synechiae0HMX1 CL E G H31665017OMIM:612109Oculoauricular syndrome2
HP:0007833HP:0007833Anterior chamber synechiae0IL2RA CL E G H35596008ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional65
HP:0007833HP:0007833Anterior chamber synechiae0IL2RB CL E G H35606009ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional
HP:0007833HP:0007833Anterior chamber synechiae0LCA5 CL E G H16769131923ORPHA:364055Severe early-childhood-onset retinal dystrophy70
HP:0007833HP:0007833Anterior chamber synechiae0LRAT CL E G H92276685ORPHA:364055Severe early-childhood-onset retinal dystrophy62
HP:0007833HP:0007833Anterior chamber synechiae0MIR204 CL E G H40698731582OMIM:616722Retinal dystrophy and iris coloboma with or without congenital cataract1
HP:0007833HP:0007833Anterior chamber synechiae0NDP CL E G H46937678ORPHA:649Norrie diseaseHP:0040281 - Very frequent39
HP:0007833HP:0007833Anterior chamber synechiae0OVOL2 CL E G H5849515804OMIM:122000Corneal dystrophy, posterior polymorphous, 14
HP:0007833HP:0007833Anterior chamber synechiae0OVOL2 CL E G H5849515804ORPHA:98973Posterior polymorphous corneal dystrophy4
HP:0007833HP:0007833Anterior chamber synechiae0PAX6 CL E G H50808620OMIM:604229Anterior segment dysgenesis 5, multiple subtypes194
HP:0007833HP:0007833Anterior chamber synechiae0PAX6 CL E G H50808620ORPHA:708Peters anomaly194
HP:0007833HP:0007833Anterior chamber synechiae0PITX2 CL E G H53089005ORPHA:708Peters anomaly51
HP:0007833HP:0007833Anterior chamber synechiae0PTPN2 CL E G H57719650ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional
HP:0007833HP:0007833Anterior chamber synechiae0PTPN22 CL E G H261919652ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional3
HP:0007833HP:0007833Anterior chamber synechiae0PXDN CL E G H783714966OMIM:269400Corneal opacification with other ocular anomalies22
HP:0007833HP:0007833Anterior chamber synechiae0RPE65 CL E G H612110294ORPHA:364055Severe early-childhood-onset retinal dystrophy129
HP:0007833HP:0007833Anterior chamber synechiae0SPATA7 CL E G H5581220423ORPHA:364055Severe early-childhood-onset retinal dystrophy48
HP:0007833HP:0007833Anterior chamber synechiae0STAT4 CL E G H677511365ORPHA:85410Oligoarticular juvenile idiopathic arthritisHP:0040283 - Occasional2
HP:0007833HP:0007833Anterior chamber synechiae0VSX1 CL E G H3081312723OMIM:614195Craniofacial anomalies and anterior segment dysgenesis syndrome47
HP:0007833HP:0007833Anterior chamber synechiae0VSX1 CL E G H3081312723ORPHA:98973Posterior polymorphous corneal dystrophy47
HP:0007833HP:0007833Anterior chamber synechiae0ZEB1 CL E G H693511642ORPHA:98973Posterior polymorphous corneal dystrophy8
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1ASPH CL E G H444757OMIM:601552Facial dysmorphism, lens dislocation, anterior segment abnormalities, and spontaneous filtering blebs4
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1ATOH7 CL E G H22020213907OMIM:221900Persistent hyperplastic primary vitreous, autosomal recessive.4
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1COL18A1 CL E G H807812195OMIM:618880GLAUCOMA, PRIMARY CLOSED-ANGLE; GLCC177
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1COL8A2 CL E G H12962216ORPHA:98973Posterior polymorphous corneal dystrophyHP:0040283 - Occasional3
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1CYP1B1 CL E G H15452597OMIM:617315ANTERIOR SEGMENT DYSGENESIS 6; ASGD6101
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1CYP1B1 CL E G H15452597ORPHA:708Peters anomalyHP:0040281 - Very frequent101
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1FOXC1 CL E G H22963800OMIM:602482Axenfeld-rieger syndrome, type 363
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1FOXC1 CL E G H22963800ORPHA:708Peters anomalyHP:0040281 - Very frequent63
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1FOXE3 CL E G H23013808OMIM:610256Anterior segment dysgenesis 2.23
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1FOXE3 CL E G H23013808ORPHA:708Peters anomalyHP:0040281 - Very frequent23
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1GRHL2 CL E G H799772799ORPHA:98973Posterior polymorphous corneal dystrophyHP:0040283 - Occasional33
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1HMX1 CL E G H31665017OMIM:612109Oculoauricular syndrome2
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1LCA5 CL E G H16769131923ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040283 - Occasional70
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1LRAT CL E G H92276685ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040283 - Occasional62
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1MIR204 CL E G H40698731582OMIM:616722Retinal dystrophy and iris coloboma with or without congenital cataract.1
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1OVOL2 CL E G H5849515804OMIM:122000Corneal dystrophy, posterior polymorphous, 14
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1OVOL2 CL E G H5849515804ORPHA:98973Posterior polymorphous corneal dystrophyHP:0040283 - Occasional4
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1PAX6 CL E G H50808620OMIM:604229Anterior segment dysgenesis 5, multiple subtypes.194
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1PAX6 CL E G H50808620ORPHA:708Peters anomalyHP:0040281 - Very frequent194
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1PITX2 CL E G H53089005ORPHA:708Peters anomalyHP:0040281 - Very frequent51
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1PXDN CL E G H783714966OMIM:269400Corneal opacification with other ocular anomalies22
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1RPE65 CL E G H612110294ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040283 - Occasional129
HP:0007833HP:0011484Posterior synechiae of the anterior chamber1SPATA7 CL E G H5581220423ORPHA:364055Severe early-childhood-onset retinal dystrophyHP:0040283 - Occasional48
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1VSX1 CL E G H3081312723OMIM:614195Craniofacial anomalies and anterior segment dysgenesis syndrome47
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1VSX1 CL E G H3081312723ORPHA:98973Posterior polymorphous corneal dystrophyHP:0040283 - Occasional47
HP:0007833HP:0011483Anterior synechiae of the anterior chamber1ZEB1 CL E G H693511642ORPHA:98973Posterior polymorphous corneal dystrophyHP:0040283 - Occasional8


Genes (29) :ANKRD55 ASPH ATOH7 B3GLCT CD247 COL18A1 COL8A2 CYP1B1 FOXC1 FOXE3 GRHL2 HMX1 IL2RA IL2RB LCA5 LRAT MIR204 NDP OVOL2 PAX6 PITX2 PTPN2 PTPN22 PXDN RPE65 SPATA7 STAT4 VSX1 ZEB1

Diseases (18) :ORPHA:85410 OMIM:601552 OMIM:221900 ORPHA:709 OMIM:618880 ORPHA:98973 OMIM:617315 ORPHA:708 OMIM:602482 OMIM:610256 OMIM:612109 ORPHA:364055 OMIM:616722 ORPHA:649 OMIM:122000 OMIM:604229 OMIM:269400 OMIM:614195
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.