Human Phenotype Ontology 
Grandparent Node:
Palmar hyperkeratosis (HP:0010765)help
Grandparent Node:
Plantar hyperkeratosis (HP:0007556)help
Parent Node:
Palmoplantar hyperkeratosis (HP:0000972)help
..Starting node
Focal friction-related palmoplantar hyperkeratosis (HP:0007497)help
Term ID: 7497
Name: Focal friction-related palmoplantar hyperkeratosis
Synonym: Hyperkeratosis, palmoplantar, focal friction-related
Definition: Hyperkeratosis affecting the palm of the hand and the sole of the foot in areas exposed to friction.
Reference: HP:0007497
Genes and Diseases:
       Child Nodes:

 Sister Nodes: 
..expandCongenital palmoplantar hyperkeratosis (HP:0007545) help
..expandCongenital symmetrical palmoplantar keratosis (HP:0007553) help
..expandDiffuse palmoplantar hyperkeratosis (HP:0007447) help
..expandobsolete Palmoplantar keratosis with erythema and scale (HP:0007548) help
..expandPunctate palmoplantar hyperkeratosis (HP:0007530) help
..expandSpinous keratoses of palms and soles (HP:0007613) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007497HP:0007497Focal friction-related palmoplantar hyperkeratosis0KRT14 CL E G H38616416ORPHA:79400Localized epidermolysis bullosa simplexHP:0040281 - Very frequent110
HP:0007497HP:0007497Focal friction-related palmoplantar hyperkeratosis0KRT5 CL E G H38526442ORPHA:79400Localized epidermolysis bullosa simplexHP:0040281 - Very frequent173

Genes (2) :KRT14 KRT5

Diseases (1) :ORPHA:79400

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.