Human Phenotype Ontology 
Grandparent Node:
Epidermal thickening (HP:0011368)help
Parent Node:
Abnormal perifollicular morphology (HP:0031285)help
Parent Node:
Hyperkeratosis (HP:0000962)help
..Starting node
Perifollicular hyperkeratosis (HP:0007468)help
Term ID: 7468
Name: Perifollicular hyperkeratosis
Definition: Increased amount of keratin (visible as white scales) surrounding hair follicles.
Reference: HP:0007468
Genes and Diseases:
       Child Nodes:

 Sister Nodes: 
..expandCircumungual hyperkeratosis (HP:0008399) help
..expandCobblestone-like hyperkeratosis (HP:0031288) help
..expandEpidermal hyperkeratosis (HP:0007543) help
..expandFollicular hyperkeratosis (HP:0007502) help
..expandGeneralized hyperkeratosis (HP:0005595) help
..expandGingival hyperkeratosis (HP:0000222) help
..expandHyperkeratosis lenticularis perstans (HP:0007570) help
..expandHyperkeratosis over edematous areas (HP:0007448) help
..expandHyperkeratosis with erythema (HP:0007390) help
..expandHyperkeratotic papule (HP:0045059) help
..expandHyperparakeratosis (HP:0040009) help
..expandLinear arrays of macular hyperkeratoses in flexural areas (HP:0007490) help
..expandobsolete Hyperkeratosis pilaris (HP:0040180) help
..expandOrthokeratotic hyperkeratosis (HP:0025080) help
..expandPalmar hyperkeratosis (HP:0010765) help
..expandPalmoplantar keratoderma (HP:0000982) help
..expandPlantar hyperkeratosis (HP:0007556) help
..expandStreaks of hyperkeratosis along each finger onto the palm (HP:0007501) help
..expandSubungual hyperkeratosis (HP:0008392) help
..expandSubungual hyperkeratotic fragments (HP:0008410) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007468HP:0007468Perifollicular hyperkeratosis0HLA-DRA CL E G H31224947ORPHA:505Graham Little-Piccardi-Lassueur syndromeHP:0040281 - Very frequent
HP:0007468HP:0007468Perifollicular hyperkeratosis0KRT81 CL E G H38876458OMIM:158000MONILETHRIX.3
HP:0007468HP:0007468Perifollicular hyperkeratosis0KRT83 CL E G H38896460OMIM:158000MONILETHRIX.65
HP:0007468HP:0007468Perifollicular hyperkeratosis0KRT86 CL E G H38926463OMIM:158000MONILETHRIX.10

Genes (4) :HLA-DRA KRT81 KRT83 KRT86

Diseases (2) :ORPHA:505 OMIM:158000

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.