Human Phenotype Ontology 
Grandparent Node:
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Palmar hyperkeratosis (HP:0010765)help
Grandparent Node:
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Plantar hyperkeratosis (HP:0007556)help
Parent Node:
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Palmoplantar hyperkeratosis (HP:0000972)help
..Starting node
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Diffuse palmoplantar hyperkeratosis (HP:0007447)help
Term ID: 7447
Name: Diffuse palmoplantar hyperkeratosis
Synonym: Diffuse palmoplantar keratoderma; Hyperkeratosis, diffuse palmoplantar
Definition: Diffuse abnormal thickening of the skin on the palms and soles.
Comments:
Reference: HP:0007447
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandCongenital palmoplantar hyperkeratosis (HP:0007545) help
..expandCongenital symmetrical palmoplantar keratosis (HP:0007553) help
..expandFocal friction-related palmoplantar hyperkeratosis (HP:0007497) help
..expandPalmoplantar keratosis with erythema and scale (HP:0007548) help
..expandPunctate palmoplantar hyperkeratosis (HP:0007530) help
..expandSpinous keratoses of palms and soles (HP:0007613) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0007447HP:0007447Diffuse palmoplantar hyperkeratosis0RHBDF2 CL E G H79651148500Howel-Evans syndrome148500C1835664OMIM117620788614404
 
HPO disease - gene - phenotype less frequent non-typical associations:


Genes (1) :RHBDF2

Diseases (1) :148500
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.