Human Phenotype Ontology 
Grandparent Node:
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Abnormal fear/anxiety-related behavior (HP:0100852)help
Parent Node:
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Anxiety (HP:0000739)help
..Starting node
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Episodic paroxysmal anxiety (HP:0000740)help
Term ID: 740
Name: Episodic paroxysmal anxiety
Synonym:
Definition: Recurrent attacks of severe anxiety, whose occurence is not restricted to any particular situation or set of circumstances and is therefore unpredictable.
Comments:
Reference: HP:0000740
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000740HP:0000740Episodic paroxysmal anxiety0DLST CL E G H17432911ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent
HP:0000740HP:0000740Episodic paroxysmal anxiety0DNMT3A CL E G H17882978ORPHA:276621Sporadic pheochromocytoma/secreting paragangliomaHP:0040282 - Frequent44
HP:0000740HP:0000740Episodic paroxysmal anxiety0EPAS1 CL E G H20343374ORPHA:276621Sporadic pheochromocytoma/secreting paragangliomaHP:0040282 - Frequent112
HP:0000740HP:0000740Episodic paroxysmal anxiety0FH CL E G H22713700ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent301
HP:0000740HP:0000740Episodic paroxysmal anxiety0KIF1B CL E G H2309516636ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent202
HP:0000740HP:0000740Episodic paroxysmal anxiety0MAX CL E G H41496913ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent84
HP:0000740HP:0000740Episodic paroxysmal anxiety0MDH2 CL E G H41916971ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent4
HP:0000740HP:0000740Episodic paroxysmal anxiety0NF1 CL E G H47637765ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent1952
HP:0000740HP:0000740Episodic paroxysmal anxiety0RET CL E G H59799967ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent572
HP:0000740HP:0000740Episodic paroxysmal anxiety0RET CL E G H59799967ORPHA:276621Sporadic pheochromocytoma/secreting paragangliomaHP:0040282 - Frequent572
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHA CL E G H638910680ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent304
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHAF2 CL E G H5494926034ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent55
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHB CL E G H639010681ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent237
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHB CL E G H639010681OMIM:115310Paragangliomas 4.237
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHB CL E G H639010681ORPHA:276621Sporadic pheochromocytoma/secreting paragangliomaHP:0040282 - Frequent237
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHC CL E G H639110682ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent147
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHC CL E G H639110682OMIM:605373Paragangliomas 3.147
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHD CL E G H639210683ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent129
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHD CL E G H639210683OMIM:168000Paragangliomas 1.129
HP:0000740HP:0000740Episodic paroxysmal anxiety0SDHD CL E G H639210683ORPHA:276621Sporadic pheochromocytoma/secreting paragangliomaHP:0040282 - Frequent129
HP:0000740HP:0000740Episodic paroxysmal anxiety0SLC25A11 CL E G H840210981ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent
HP:0000740HP:0000740Episodic paroxysmal anxiety0TMEM127 CL E G H5565426038ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent131
HP:0000740HP:0000740Episodic paroxysmal anxiety0VHL CL E G H742812687ORPHA:29072Hereditary pheochromocytoma-paragangliomaHP:0040282 - Frequent490
HP:0000740HP:0000740Episodic paroxysmal anxiety0VHL CL E G H742812687ORPHA:276621Sporadic pheochromocytoma/secreting paragangliomaHP:0040282 - Frequent490


Genes (17) :DLST DNMT3A EPAS1 FH KIF1B MAX MDH2 NF1 RET SDHA SDHAF2 SDHB SDHC SDHD SLC25A11 TMEM127 VHL

Diseases (5) :ORPHA:29072 ORPHA:276621 OMIM:115310 OMIM:605373 OMIM:168000
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.