Human Phenotype Ontology 
Grandparent Node:
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Neoplasm (HP:0002664)help
Parent Node:
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Abnormality of the genitourinary system (HP:0000119)help
Parent Node:
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Neoplasm by anatomical site (HP:0011793)help
..Starting node
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Neoplasm of the genitourinary tract (HP:0007379)help
Term ID: 7379
Name: Neoplasm of the genitourinary tract
Synonym: Genitourinary tract neoplasia; Genitourinary tract neoplasm; Genitourinary tract tumors; Genitourinary tract tumours; Neoplasm of the GU tract
Definition: A tumor (abnormal growth of tissue) of the genitourinary system.
Comments:
Reference: HP:0007379
Genes and Diseases:
 
       Child Nodes:
........expandMalignant genitourinary tract tumor (HP:0006758) help
........expandBenign genitourinary tract neoplasm (HP:0006778) help
........expandUrinary tract neoplasm (HP:0010786) help
................... HP:0009725 Bladder neoplasm
................... HP:0009726 Renal neoplasm
................... HP:0100516 Neoplasm of the ureter
................... HP:0100517 Neoplasm of the urethra
........expandGenital neoplasm (HP:0010787) help
................... HP:0010784 Uterine neoplasm
................... HP:0010785 Gonadal neoplasm
................... HP:0030394 Fallopian tube carcinoma
................... HP:0030416 Vulvar neoplasm
................... HP:0100650 Vaginal neoplasm
................... HP:0100848 Neoplasm of the male external genitalia

 Sister Nodes: 
..expandHematological neoplasm (HP:0004377) help
..expandMalignant mesothelioma (HP:0100001) help
..expandNeoplasm of fatty tissue (HP:0200013) help
..expandNeoplasm of head and neck (HP:0012288) help
..expandNeoplasm of striated muscle (HP:0009728) help
..expandNeoplasm of the breast (HP:0100013) help
..expandNeoplasm of the ear (HP:0012780) help
..expandNeoplasm of the endocrine system (HP:0100568) help
..expandNeoplasm of the eye (HP:0100012) help
..expandNeoplasm of the gastrointestinal tract (HP:0007378) help
..expandNeoplasm of the heart (HP:0100544) help
..expandNeoplasm of the lip (HP:0100604) help
..expandNeoplasm of the nail (HP:0100826) help
..expandNeoplasm of the nervous system (HP:0004375) help
..expandNeoplasm of the oral cavity (HP:0100649) help
..expandNeoplasm of the pancreas (HP:0002894) help
..expandNeoplasm of the respiratory system (HP:0100606) help
..expandNeoplasm of the skeletal system (HP:0010622) help
..expandNeoplasm of the skin (HP:0008069) help
..expandNeoplasm of the thymus (HP:0100521) help
..expandRetroperitoneal chemodectomas (HP:0006729) help
..expandSoft tissue neoplasm (HP:0031459) help
..expandVascular neoplasm (HP:0100742) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007379HP:0007379Neoplasm of the genitourinary tract0 CL E G H
HP:0007379HP:0006778Benign genitourinary tract neoplasm1 CL E G H
HP:0007379HP:0010786Urinary tract neoplasm1 CL E G H
HP:0007379HP:0010787Genital neoplasm1 CL E G H
HP:0007379HP:0006758Malignant genitourinary tract tumor1 CL E G H
HP:0007379HP:0100517Neoplasm of the urethra2 CL E G H
HP:0007379HP:0010785Gonadal neoplasm2 CL E G H
HP:0007379HP:0009725Bladder neoplasm2 CL E G H
HP:0007379HP:0033020Female reproductive system neoplasm2 CL E G H
HP:0007379HP:0009726Renal neoplasm2 CL E G H
HP:0007379HP:0033019Male reproductive system neoplasm2 CL E G H
HP:0007379HP:0100516Neoplasm of the ureter2 CL E G H
HP:0007379HP:0030421Epididymal neoplasm3 CL E G H
HP:0007379HP:0002862Bladder carcinoma3 CL E G H
HP:0007379HP:0008696Renal hamartoma3 CL E G H
HP:0007379HP:0030394Fallopian tube carcinoma3 CL E G H
HP:0007379HP:0008663Renal sarcoma3 CL E G H
HP:0007379HP:0011794Embryonal renal neoplasm3 CL E G H
HP:0007379HP:0100615Ovarian neoplasm3 CL E G H
HP:0007379HP:0006735Renal cortical adenoma3 CL E G H
HP:0007379HP:0006762Renal pelvic carcinoma3 CL E G H
HP:0007379HP:0025635Ureteral polyp3 CL E G H
HP:0007379HP:0100650Vaginal neoplasm3 CL E G H
HP:0007379HP:0010784Uterine neoplasm3 CL E G H
HP:0007379HP:0005584Renal cell carcinoma3 CL E G H
HP:0007379HP:0100787Prostate neoplasm3 CL E G H
HP:0007379HP:0011798Renal oncocytoma3 CL E G H
HP:0007379HP:0010788Testicular neoplasm3 CL E G H
HP:0007379HP:0100728Germ cell neoplasia3 CL E G H
HP:0007379HP:0030416Vulvar neoplasm3 CL E G H
HP:0007379HP:0030409Renal transitional cell carcinoma3 CL E G H
HP:0007379HP:0100848Neoplasm of the male external genitalia3 CL E G H
HP:0007379HP:0031521Vaginal clear cell adenocarcinoma4 CL E G H
HP:0007379HP:0000131Uterine leiomyoma4 CL E G H
HP:0007379HP:0009792Teratoma4 CL E G H
HP:0007379HP:0100621Dysgerminoma4 CL E G H
HP:0007379HP:0006766Papillary renal cell carcinoma4 CL E G H
HP:0007379HP:0009715Papillary cystadenoma of the epididymis4 CL E G H
HP:0007379HP:0010618Ovarian fibroma4 CL E G H
HP:0007379HP:0031918Ovarian sex cord-stromal tumor4 CL E G H
HP:0007379HP:0030420Vulvar adenocarcinoma4 CL E G H
HP:0007379HP:0100618Leydig cell neoplasia4 CL E G H
HP:0007379HP:0031522Cervical clear cell adenocarcinoma4 CL E G H
HP:0007379HP:0008643Nephroblastomatosis4 CL E G H
HP:0007379HP:0030079Cervix cancer4 CL E G H
HP:0007379HP:0100619Sertoli cell neoplasm4 CL E G H
HP:0007379HP:0006770Clear cell renal cell carcinoma4 CL E G H
HP:0007379HP:0012125Prostate cancer4 CL E G H
HP:0007379HP:0000030Testicular gonadoblastoma4 CL E G H
HP:0007379HP:0025318Ovarian carcinoma4 CL E G H
HP:0007379HP:0100617Testicular seminoma4 CL E G H
HP:0007379HP:0006774Ovarian papillary adenocarcinoma4 CL E G H
HP:0007379HP:0030417Squamous cell carcinoma of the vulva4 CL E G H
HP:0007379HP:0100849Neoplasm of the scrotum4 CL E G H
HP:0007379HP:0012226Ovarian teratoma4 CL E G H
HP:0007379HP:0002667Nephroblastoma4 CL E G H
HP:0007379HP:0010788Testicular neoplasm4 CL E G H
HP:0007379HP:0100620Germinoma4 CL E G H
HP:0007379HP:0031920Malignant ovarian granulosa cell tumor4 CL E G H
HP:0007379HP:0030419Bartholin gland carcinoma4 CL E G H
HP:0007379HP:0100850Neoplasm of the penis4 CL E G H
HP:0007379HP:0030418Vulvar melanoma4 CL E G H
HP:0007379HP:0012114Endometrial carcinoma4 CL E G H
HP:0007379HP:0002891Uterine leiomyosarcoma4 CL E G H
HP:0007379HP:0006740Transitional cell carcinoma of the bladder4 CL E G H
HP:0007379HP:0025451Testicular adrenal rest tumor4 CL E G H
HP:0007379HP:0000150Gonadoblastoma4 CL E G H
HP:0007379HP:0100005Testicular mesothelioma4 CL E G H
HP:0007379HP:0000149Ovarian gonadoblastoma4 CL E G H
HP:0007379HP:0006772Renal angiomyolipoma4 CL E G H
HP:0007379HP:0100616Testicular teratoma4 CL E G H
HP:0007379HP:0031502Trophoblastic tumor4 CL E G H
HP:0007379HP:0032202Vulvar intraepithelial neoplasia4 CL E G H
HP:0007379HP:0100881Congenital mesoblastic nephroma4 CL E G H
HP:0007379HP:0100618Leydig cell neoplasia5 CL E G H
HP:0007379HP:0011795Intralobar nephroblastomatosis5 CL E G H
HP:0007379HP:0100619Sertoli cell neoplasm5 CL E G H
HP:0007379HP:0000030Testicular gonadoblastoma5 CL E G H
HP:0007379HP:0030736Sacrococcygeal teratoma5 CL E G H
HP:0007379HP:0100617Testicular seminoma5 CL E G H
HP:0007379HP:0008204Precocious puberty with Sertoli cell tumor5 CL E G H
HP:0007379HP:0012226Ovarian teratoma5 CL E G H
HP:0007379HP:0100312Cerebral germinoma5 CL E G H
HP:0007379HP:0031227Nasopharyngeal teratoma5 CL E G H
HP:0007379HP:0011674Cardiac teratoma5 CL E G H
HP:0007379HP:0025451Testicular adrenal rest tumor5 CL E G H
HP:0007379HP:0030741Mediastinal teratoma5 CL E G H
HP:0007379HP:0006732Papillary renal cell carcinoma type 25 CL E G H
HP:0007379HP:0100005Testicular mesothelioma5 CL E G H
HP:0007379HP:0000149Ovarian gonadoblastoma5 CL E G H
HP:0007379HP:0100768Choriocarcinoma5 CL E G H
HP:0007379HP:0100616Testicular teratoma5 CL E G H
HP:0007379HP:0030983Ovarian thecoma5 CL E G H
HP:0007379HP:0025274Ovarian dermoid cyst5 CL E G H
HP:0007379HP:0011796Perilobar nephroblastomatosis5 CL E G H
HP:0007379HP:0030755Craniofacial teratoma5 CL E G H
HP:0007379HP:0100621Dysgerminoma5 CL E G H
HP:0007379HP:0011797Papillary renal cell carcinoma type 15 CL E G H
HP:0007379HP:0030767Epignathus5 CL E G H
HP:0007379HP:0031919Juvenile type ovarian granulosa cell tumor5 CL E G H
HP:0007379HP:0009793Presacral teratoma6 CL E G H
HP:0007379HP:0030739Altman type III sacrococcygeal teratoma6 CL E G H
HP:0007379HP:0025274Ovarian dermoid cyst6 CL E G H
HP:0007379HP:0030738Altman type II sacrococcygeal teratoma6 CL E G H
HP:0007379HP:0030737Altman type I sacrococcygeal teratoma6 CL E G H
HP:0007379HP:0008204Precocious puberty with Sertoli cell tumor6 CL E G H


Genes (160) :AAGAB AKT1 ALX4 APC APC2 AR ATP7A AXIN2 BAP1 BARD1 BMPER BRCA1 BRCA2 BRIP1 BUB1 BUB1B BUB3 C11ORF95 CDC73 CDH1 CDKN1B CDKN1C CDKN2A CEP57 CHEK2 COL14A1 CREBBP CTNNB1 DCC DHH DICER1 DIS3L2 DLC1 DMRT3 DOCK8 EP300 EPCAM EWSR1 EXT2 FAN1 FERMT1 FGFR2 FGFR3 FH FIBP FLCN FLI1 FN1 FOXE1 GATA4 GNAS GPC3 GPC4 H19 H19-ICR HABP2 HDAC4 HMGA2 HNF1A HNF1B HNF4A HRAS IDH1 IDH2 IGF2 INHBA KCNQ1 KCNQ1OT1 KEAP1 KIF1B KIT KLF6 KLLN KRAS LMNA MAD1L1 MAP3K1 MAX MDH2 MET MINPP1 MLH1 MLH3 MNX1 MRE11 MSH2 MSH3 MSH6 MXI1 NBN NOD2 NR0B1 NR5A1 NRAS NSD1 NTHL1 OGG1 OPCML PALB2 PALLD PAX6 PHF21A PIK3CA PMS1 PMS2 POLD1 POLE POU6F2 PRCC PRKAR1A PRKN PTCH1 PTCH2 PTEN RAD50 RAD51 RAD51C RAD51D RB1 RELA REST RET RNASEL RNF139 RNF43 SDHA SDHAF2 SDHB SDHC SDHD SEC23B SETBP1 SETD2 SLC49A4 SMAD4 SOX9 SRC SRY STAG3 STK11 STS SUFU TBX18 TFE3 TGFBR2 TMEM127 TP53 TRIM28 TRIM37 TRIP13 TSC1 TSC2 VAMP7 VHL WNT10A WRN WT1 WWOX ZFHX3 ZFPM2

Diseases (124) :144 587 158320 90797 2908 135150 615107 79474 454840 616415 902 79501 201 744 114500 304150 614327 145 617883 1052 251636 143 99880 145001 276152 276399 267000 83469 87 29072 523 150800 122 144700 370348 601894 562 93111 218040 163634 614337 1359 137608 65285 109 157798 115310 615723 2869 175200 143400 300854 191100 613254 892 193300 50944 615109 167000 52022 79665 99429 608022 1333 654 194070 257300 608089 610755 130650 180849 168563 233420 180295 2849 251510 217390 123500 109800 273300 617107 319487 373 312870 2128 180860 194071 1001 150699 213504 176807 363618 613762 605074 480536 614350 90340 117550 610832 194072 276280 615108 602501 447877 77301 109400 158350 601518 798 269150 1772 281090 151623 253250 538 805 256370 194080 136680 220 347 821 1552 176450
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.