Human Phenotype Ontology 
Grandparent Node:
expandAbnormal nervous system physiology (HP:0012638)help
Parent Node:
expandBehavioral abnormality (HP:0000708)help
..Starting node
..expandLack of spontaneous play (HP:0000721)help
Term ID: 721
Name: Lack of spontaneous play
Synonym: Lack of spontaneous play
Definition:
Comments:
Reference: HP:0000721
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal consumption behavior (HP:0040202) help
..expandAbnormal emotion/affect behavior (HP:0100851) help
..expandAbnormal social behavior (HP:0012433) help
..expandAbnormal temper tantrums (HP:0025160) help
..expandAddictive behavior (HP:0030858) help
..expandAutistic behavior (HP:0000729) help
..expandDelusions (HP:0000746) help
..expandDrooling (HP:0002307) help
..expandEcholalia (HP:0010529) help
..expandHallucinations (HP:0000738) help
..expandHyperorality (HP:0000710) help
..expandImpairment in personality functioning (HP:0031466) help
..expandInflexible adherence to routines or rituals (HP:0000732) help
..expandLack of insight (HP:0000757) help
..expandLow frustration tolerance (HP:0000744) help
..expandMania (HP:0100754) help
..expandMutism (HP:0002300) help
..expandObsessive-compulsive behavior (HP:0000722) help
..expandobsolete Psychomotor retardation (HP:0025356) help
..expandOppositional defiant disorder (HP:0010865) help
..expandPerseveration (HP:0030223) help
..expandPersonality changes (HP:0000751) help
..expandPhotophobia (HP:0000613) help
..expandPseudobulbar behavioral symptoms (HP:0002193) help
..expandPsychosis (HP:0000709) help
..expandRestlessness (HP:0000711) help
..expandSchizophrenia (HP:0100753) help
..expandSelf-neglect (HP:0025479) help
..expandShort attention span (HP:0000736) help
..expandSleep disturbance (HP:0002360) help
..expandSound sensitivity (HP:0025112) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000721HP:0000721Lack of spontaneous play0MECP2 CL E G H42046990OMIM:300496Autism susceptibility, X-linked 3.950
HP:0000721HP:0000721Lack of spontaneous play0NLGN3 CL E G H5441314289OMIM:300494Asperger syndrome, X-linked, susceptibility to, 1.24
HP:0000721HP:0000721Lack of spontaneous play0NLGN3 CL E G H5441314289OMIM:300425Autism susceptibility, X-linked 1.24
HP:0000721HP:0000721Lack of spontaneous play0NLGN4X CL E G H5750214287OMIM:300497Asperger syndrome susceptibility, X-linked 2.57
HP:0000721HP:0000721Lack of spontaneous play0NLGN4X CL E G H5750214287OMIM:300495Autism, susceptibility to, X-linked 2.57
HP:0000721HP:0000721Lack of spontaneous play0SNRPN CL E G H663811164OMIM:209850Autism susceptibility 1.37


Genes (4) :MECP2 NLGN3 NLGN4X SNRPN

Diseases (6) :OMIM:300496 OMIM:300494 OMIM:300425 OMIM:300497 OMIM:300495 OMIM:209850
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.