Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of the dentition (HP:0000164)

Parent Node:
Abnormality of dental eruption (HP:0006292)

..Starting node
..Delayed eruption of teeth (HP:0000684)

Term ID:

684

Name:

Delayed eruption of teeth

Synonym:

Delayed dental development; Delayed dental eruption; Delayed eruption; Delayed eruption of teeth; Delayed teeth eruption; Delayed tooth eruption; Eruption, delayed; Late eruption of teeth; Late tooth eruption

Definition:

Delayed tooth eruption, which can be defined as tooth eruption more than 2 SD beyond the mean eruption age.

Comments:

Reference:

HP:0000684

Genes and Diseases:

Child Nodes:

........

Delayed eruption of primary teeth (HP:0000680)

........

Delayed eruption of permanent teeth (HP:0000696)

................... HP:0006291 Marked delay in eruption of permanent teeth
................... HP:0006321 Multiple non-erupting secondary teeth
................... HP:0008498 No permanent dentition

Sister Nodes:

Advanced eruption of teeth (HP:0006288)

Eruption failure (HP:0000706)

Persistence of primary teeth (HP:0006335)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ABCA5 CL E G H	23461	35	ORPHA:2026	Gingival fibromatosis-hypertrichosis syndrome	HP:0040282 - Frequent	1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ACP5 CL E G H	54	124	ORPHA:1855	Spondyloenchondrodysplasia	HP:0040283 - Occasional	16
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ADAMTS3 CL E G H	9508	219	ORPHA:2136	Hennekam syndrome	HP:0040281 - Very frequent	1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ADAMTSL1 CL E G H	92949	14632	ORPHA:521445	Microcephaly-facial dysmorphism-ocular anomalies-multiple congenital anomalies syndrome
HP:0000684	HP:0000684	Delayed eruption of teeth	0	AMER1 CL E G H	139285	26837	ORPHA:2780	Osteopathia striata-cranial sclerosis syndrome	HP:0040282 - Frequent	34
HP:0000684	HP:0000684	Delayed eruption of teeth	0	AMMECR1 CL E G H	9949	467	OMIM:300990	Midface hypoplasia, hearing impairment, elliptocytosis, and nephrocalcinosis	.	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ANAPC1 CL E G H	64682	19988	ORPHA:221008	Rothmund-Thomson syndrome type 1	HP:0040283 - Occasional	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ANTXR1 CL E G H	84168	21014	ORPHA:2067	GAPO syndrome	HP:0040281 - Very frequent	8
HP:0000684	HP:0000684	Delayed eruption of teeth	0	APC2 CL E G H	10297	24036	ORPHA:821	Sotos syndrome		1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ARID1A CL E G H	8289	11110	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	88
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ARID1A CL E G H	8289	11110	OMIM:614607	Coffin-Siris syndrome 2		88
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ARID1B CL E G H	57492	18040	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	219
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ARID1B CL E G H	57492	18040	OMIM:135900	Coffin-Siris syndrome 1	.	219
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ARID2 CL E G H	196528	18037	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	25
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ARSB CL E G H	411	714	OMIM:253200	Mucopolysaccharidosis, type VI		120
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ATP6V0A2 CL E G H	23545	18481	ORPHA:2834	Wrinkly skin syndrome	HP:0040281 - Very frequent	140
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ATP6V0A2 CL E G H	23545	18481	OMIM:278250	Wrinkly skin syndrome	.	140
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ATP6V1B2 CL E G H	526	854	ORPHA:79500	DOORS syndrome		5
HP:0000684	HP:0000684	Delayed eruption of teeth	0	AXIN2 CL E G H	8313	904	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	435
HP:0000684	HP:0000684	Delayed eruption of teeth	0	BCOR CL E G H	54880	20893	ORPHA:568	Microphthalmia, Lenz type	HP:0040283 - Occasional	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	BCOR CL E G H	54880	20893	OMIM:300166	Microphthalmia, syndromic 2		101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	BCOR CL E G H	54880	20893	ORPHA:2712	Oculofaciocardiodental syndrome	HP:0040281 - Very frequent	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	BRD4 CL E G H	23476	13575	ORPHA:199	Cornelia de Lange syndrome	HP:0040281 - Very frequent
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CAMK2B CL E G H	816	1461	OMIM:617799	Mental retardation, autosomal dominant 54
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CCBE1 CL E G H	147372	29426	OMIM:235510	Hennekam lymphangiectasia-lymphedema syndrome	.	147
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CCBE1 CL E G H	147372	29426	ORPHA:2136	Hennekam syndrome	HP:0040281 - Very frequent	147
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CCDC8 CL E G H	83987	25367	ORPHA:2616	3M syndrome	HP:0040282 - Frequent	5
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CDH11 CL E G H	1009	1750	OMIM:211380	Elsahy-Waters syndrome	.	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CDH11 CL E G H	1009	1750	OMIM:619736	TEEBI HYPERTELORISM SYNDROME 2; TBHS2		2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CHD7 CL E G H	55636	20626	ORPHA:138	CHARGE syndrome	HP:0040282 - Frequent	515
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CHST3 CL E G H	9469	1971	ORPHA:263463	CHST3-related skeletal dysplasia	HP:0040282 - Frequent	165
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CHST3 CL E G H	9469	1971	OMIM:143095	Spondyloepiphyseal dysplasia with congenital joint dislocations	.	165
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CLCN7 CL E G H	1186	2025	ORPHA:667	Autosomal recessive malignant osteopetrosis	HP:0040281 - Very frequent	102
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CTSK CL E G H	1513	2536	ORPHA:763	Pycnodysostosis	HP:0040281 - Very frequent	39
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CTSK CL E G H	1513	2536	OMIM:265800	PYCNODYSOSTOSIS		39
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CUL7 CL E G H	9820	21024	ORPHA:2616	3M syndrome	HP:0040282 - Frequent	127
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CYP27B1 CL E G H	1594	2606	ORPHA:289157	Hypocalcemic vitamin D-dependent rickets	HP:0040283 - Occasional	41
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CYP27B1 CL E G H	1594	2606	OMIM:264700	Vitamin D hydroxylation-deficient rickets, type 1A	.	41
HP:0000684	HP:0000684	Delayed eruption of teeth	0	CYP2R1 CL E G H	120227	20580	ORPHA:289157	Hypocalcemic vitamin D-dependent rickets	HP:0040283 - Occasional	5
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DEAF1 CL E G H	10522	14677	ORPHA:819	Smith-Magenis syndrome		33
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DMP1 CL E G H	1758	2932	ORPHA:289176	Autosomal recessive hypophosphatemic rickets	HP:0040281 - Very frequent	48
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DNAJC21 CL E G H	134218	27030	ORPHA:811	Shwachman-Diamond syndrome	HP:0040284 - Very rare	5
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DPF2 CL E G H	5977	9964	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DPYD CL E G H	1806	3012	ORPHA:1675	Dihydropyrimidine dehydrogenase deficiency	HP:0040283 - Occasional	144
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DVL1 CL E G H	1855	3084	OMIM:180700	Robinow syndrome, autosomal dominant 1	.	14
HP:0000684	HP:0000684	Delayed eruption of teeth	0	DYNC2LI1 CL E G H	51626	24595	ORPHA:289	Ellis Van Creveld syndrome	HP:0040283 - Occasional	7
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EDA CL E G H	1896	3157	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	115
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EDA CL E G H	1896	3157	ORPHA:181	X-linked hypohidrotic ectodermal dysplasia	HP:0040281 - Very frequent	115
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EDA2R CL E G H	60401	17756	ORPHA:181	X-linked hypohidrotic ectodermal dysplasia	HP:0040281 - Very frequent	11
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EDARADD CL E G H	128178	14341	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	56
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EDNRA CL E G H	1909	3179	OMIM:616367	Mandibulofacial dysostosis with alopecia		3
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EFL1 CL E G H	79631	25789	ORPHA:811	Shwachman-Diamond syndrome	HP:0040284 - Very rare	1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ELMO2 CL E G H	63916	17233	ORPHA:3019	Ramon syndrome	HP:0040282 - Frequent	3
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ENPP1 CL E G H	5167	3356	ORPHA:289176	Autosomal recessive hypophosphatemic rickets	HP:0040281 - Very frequent	151
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC1 CL E G H	2067	3433	ORPHA:90322	Cockayne syndrome type 2		20
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC4 CL E G H	2072	3436	ORPHA:90321	Cockayne syndrome type 1		158
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC6 CL E G H	2074	3438	OMIM:214150	Cerebrooculofacioskeletal syndrome 1		199
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC6 CL E G H	2074	3438	ORPHA:90321	Cockayne syndrome type 1		199
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC6 CL E G H	2074	3438	ORPHA:90322	Cockayne syndrome type 2		199
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC6 CL E G H	2074	3438	OMIM:133540	Cockayne syndrome, type B		199
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC8 CL E G H	1161	3439	OMIM:216400	Cockayne syndrome A		55
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC8 CL E G H	1161	3439	ORPHA:90321	Cockayne syndrome type 1		55
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ERCC8 CL E G H	1161	3439	ORPHA:90322	Cockayne syndrome type 2		55
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EVC CL E G H	2121	3497	ORPHA:289	Ellis Van Creveld syndrome	HP:0040283 - Occasional	209
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EVC CL E G H	2121	3497	OMIM:225500	Ellis-Van creveld syndrome	.	209
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EVC2 CL E G H	132884	19747	ORPHA:289	Ellis Van Creveld syndrome	HP:0040283 - Occasional	137
HP:0000684	HP:0000684	Delayed eruption of teeth	0	EVC2 CL E G H	132884	19747	OMIM:225500	Ellis-Van creveld syndrome	.	137
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FAM20A CL E G H	54757	23015	ORPHA:1031	Enamel-renal syndrome	HP:0040281 - Very frequent	16
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FAM20A CL E G H	54757	23015	OMIM:204690	Enamel-Renal syndrome		16
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FAT4 CL E G H	79633	23109	ORPHA:2136	Hennekam syndrome	HP:0040281 - Very frequent	114
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGD1 CL E G H	2245	3663	ORPHA:915	Aarskog-Scott syndrome	HP:0040283 - Occasional	62
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGF10 CL E G H	2255	3666	OMIM:149730	Lacrimoauriculodentodigital syndrome		17
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGF3 CL E G H	2248	3681	ORPHA:2791	Otodental syndrome	HP:0040282 - Frequent	18
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGFR1 CL E G H	2260	3688	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	172
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGFR2 CL E G H	2263	3689	OMIM:101200	Apert syndrome	.	175
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGFR2 CL E G H	2263	3689	ORPHA:87	Apert syndrome	HP:0040282 - Frequent	175
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGFR2 CL E G H	2263	3689	OMIM:149730	Lacrimoauriculodentodigital syndrome		175
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FGFR3 CL E G H	2261	3690	OMIM:149730	Lacrimoauriculodentodigital syndrome		145
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FLII CL E G H	2314	3750	ORPHA:819	Smith-Magenis syndrome
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FLNA CL E G H	2316	3754	OMIM:305620	Frontometaphyseal dysplasia	.	493
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FLNA CL E G H	2316	3754	ORPHA:2484	Melnick-Needles syndrome	HP:0040282 - Frequent	493
HP:0000684	HP:0000684	Delayed eruption of teeth	0	FLNA CL E G H	2316	3754	OMIM:309350	Melnick-Needles syndrome	.	493
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GDF5 CL E G H	8200	4220	ORPHA:63442	Angel-shaped phalango-epiphyseal dysplasia	HP:0040282 - Frequent	52
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GHR CL E G H	2690	4263	ORPHA:633	Laron syndrome	HP:0040281 - Very frequent	98
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GJA1 CL E G H	2697	4274	OMIM:218400	Craniometaphyseal dysplasia, autosomal recessive		68
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GJA1 CL E G H	2697	4274	OMIM:257850	Oculodentodigital dysplasia, autosomal recessive	.	68
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GLI1 CL E G H	2735	4317	ORPHA:289	Ellis Van Creveld syndrome	HP:0040283 - Occasional	1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNAS CL E G H	2778	4392	ORPHA:79443	Pseudohypoparathyroidism type 1A	HP:0040282 - Frequent	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNAS CL E G H	2778	4392	ORPHA:94089	Pseudohypoparathyroidism type 1B	HP:0040282 - Frequent	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNAS CL E G H	2778	4392	ORPHA:79444	Pseudohypoparathyroidism type 1C	HP:0040282 - Frequent	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNAS CL E G H	2778	4392	OMIM:103580	Pseudohypoparathyroidism, type IA	.	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNAS CL E G H	2778	4392	OMIM:612462	Pseudohypoparathyroidism, type IC	.	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNAS CL E G H	2778	4392	OMIM:612463	PSEUDOPSEUDOHYPOPARATHYROIDISM	.	101
HP:0000684	HP:0000684	Delayed eruption of teeth	0	GNB2 CL E G H	2783	4398	OMIM:619503	NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND DYSMORPHIC FACIES; NEDHYDF
HP:0000684	HP:0000684	Delayed eruption of teeth	0	HDAC4 CL E G H	9759	14063	OMIM:619797	NEURODEVELOPMENTAL DISORDER WITH CENTRAL HYPOTONIA AND DYSMORPHIC FACIES; NEDCHF		33
HP:0000684	HP:0000684	Delayed eruption of teeth	0	HDAC8 CL E G H	55869	13315	ORPHA:199	Cornelia de Lange syndrome	HP:0040281 - Very frequent	37
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IDS CL E G H	3423	5389	OMIM:309900	Mucopolysaccharidosis, type II	.	86
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IGF1 CL E G H	3479	5464	ORPHA:73272	Growth delay due to insulin-like growth factor type 1 deficiency	HP:0040282 - Frequent	91
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IKBKG CL E G H	8517	5961	OMIM:308300	Incontinentia pigmenti	.	52
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IKBKG CL E G H	8517	5961	ORPHA:464	Incontinentia pigmenti	HP:0040282 - Frequent	52
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IL11RA CL E G H	3590	5967	OMIM:614188	Craniosynostosis and dental anomalies	.	8
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IQSEC2 CL E G H	23096	29059	ORPHA:819	Smith-Magenis syndrome		119
HP:0000684	HP:0000684	Delayed eruption of teeth	0	IRF6 CL E G H	3664	6121	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	99
HP:0000684	HP:0000684	Delayed eruption of teeth	0	KAT6B CL E G H	23522	17582	ORPHA:85201	Genitopatellar syndrome	HP:0040282 - Frequent	141
HP:0000684	HP:0000684	Delayed eruption of teeth	0	KAT6B CL E G H	23522	17582	OMIM:606170	Genitopatellar syndrome	.	141
HP:0000684	HP:0000684	Delayed eruption of teeth	0	KCNH1 CL E G H	3756	6250	ORPHA:420561	Temple-Baraitser syndrome	HP:0040282 - Frequent	13
HP:0000684	HP:0000684	Delayed eruption of teeth	0	KCNH1 CL E G H	3756	6250	OMIM:135500	Zimmermann-Laband syndrome 1	.	13
HP:0000684	HP:0000684	Delayed eruption of teeth	0	KCNJ2 CL E G H	3759	6263	OMIM:170390	Andersen cardiodysrhythmic periodic paralysis		193
HP:0000684	HP:0000684	Delayed eruption of teeth	0	KCTD1 CL E G H	284252	18249	ORPHA:2036	Scalp-ear-nipple syndrome	HP:0040282 - Frequent	11
HP:0000684	HP:0000684	Delayed eruption of teeth	0	LEMD2 CL E G H	221496	21244	OMIM:619322	MARBACH-RUSTAD PROGEROID SYNDROME; MARUPS		1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	LIG4 CL E G H	3981	6601	ORPHA:235	Dubowitz syndrome	HP:0040283 - Occasional	88
HP:0000684	HP:0000684	Delayed eruption of teeth	0	LMNA CL E G H	4000	6636	ORPHA:740	Hutchinson-Gilford progeria syndrome	HP:0040283 - Occasional	645
HP:0000684	HP:0000684	Delayed eruption of teeth	0	LONP1 CL E G H	9361	9479	ORPHA:1458	CODAS syndrome	HP:0040281 - Very frequent	8
HP:0000684	HP:0000684	Delayed eruption of teeth	0	LONP1 CL E G H	9361	9479	OMIM:600373	CODAS syndrome		8
HP:0000684	HP:0000684	Delayed eruption of teeth	0	LRP6 CL E G H	4040	6698	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	26
HP:0000684	HP:0000684	Delayed eruption of teeth	0	MIA3 CL E G H	375056	24008	OMIM:619269	ODONTOCHONDRODYSPLASIA 2 WITH HEARING LOSS AND DIABETES; ODCD2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	MMP2 CL E G H	4313	7166	OMIM:259600	Multicentric osteolysis, nodulosis, and arthropathy	.	64
HP:0000684	HP:0000684	Delayed eruption of teeth	0	MSX1 CL E G H	4487	7391	ORPHA:2228	Hypodontia-dysplasia of nails syndrome	HP:0040281 - Very frequent	12
HP:0000684	HP:0000684	Delayed eruption of teeth	0	MSX1 CL E G H	4487	7391	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	12
HP:0000684	HP:0000684	Delayed eruption of teeth	0	MYSM1 CL E G H	114803	29401	ORPHA:508542	Congenital progressive bone marrow failure-B-cell immunodeficiency-skeletal dysplasia syndrome	HP:0040283 - Occasional
HP:0000684	HP:0000684	Delayed eruption of teeth	0	NAA10 CL E G H	8260	18704	ORPHA:568	Microphthalmia, Lenz type	HP:0040283 - Occasional	23
HP:0000684	HP:0000684	Delayed eruption of teeth	0	NIPBL CL E G H	25836	28862	ORPHA:199	Cornelia de Lange syndrome	HP:0040281 - Very frequent	494
HP:0000684	HP:0000684	Delayed eruption of teeth	0	NIPBL CL E G H	25836	28862	OMIM:122470	Cornelia de Lange syndrome 1	.	494
HP:0000684	HP:0000684	Delayed eruption of teeth	0	NPHS1 CL E G H	4868	7908	ORPHA:839	Congenital nephrotic syndrome, Finnish type		241
HP:0000684	HP:0000684	Delayed eruption of teeth	0	NSD1 CL E G H	64324	14234	ORPHA:821	Sotos syndrome		544
HP:0000684	HP:0000684	Delayed eruption of teeth	0	NSUN2 CL E G H	54888	25994	ORPHA:235	Dubowitz syndrome	HP:0040283 - Occasional	84
HP:0000684	HP:0000684	Delayed eruption of teeth	0	OBSL1 CL E G H	23363	29092	OMIM:612921	3-M syndrome 2	.	143
HP:0000684	HP:0000684	Delayed eruption of teeth	0	OBSL1 CL E G H	23363	29092	ORPHA:2616	3M syndrome	HP:0040282 - Frequent	143
HP:0000684	HP:0000684	Delayed eruption of teeth	0	OCRL CL E G H	4952	8108	ORPHA:534	Oculocerebrorenal syndrome of Lowe	HP:0040283 - Occasional	88
HP:0000684	HP:0000684	Delayed eruption of teeth	0	P4HB CL E G H	5034	8548	ORPHA:2050	Cole-Carpenter syndrome	HP:0040281 - Very frequent	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PAPPA2 CL E G H	60676	14615	OMIM:619489	SHORT STATURE, DAUBER-ARGENTE TYPE; SSDA		2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PAX9 CL E G H	5083	8623	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	58
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PDE4D CL E G H	5144	8783	ORPHA:950	Acrodysostosis	HP:0040282 - Frequent	113
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PDGFRB CL E G H	5159	8804	OMIM:601812	Premature aging syndrome, Penttinen type	.	28
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PIGA CL E G H	5277	8957	OMIM:301072	NEURODEVELOPMENTAL DISORDER WITH EPILEPSY AND HEMOCHROMATOSIS; NEDEPH		46
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PIGF CL E G H	5281	8962	OMIM:619356	ONYCHODYSTROPHY, OSTEODYSTROPHY, IMPAIRED INTELLECTUAL DEVELOPMENT, AND SEIZURES SYNDROME; OORS
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PIK3R1 CL E G H	5295	8979	OMIM:269880	Short syndrome	.	43
HP:0000684	HP:0000684	Delayed eruption of teeth	0	POLR3A CL E G H	11128	30074	ORPHA:447896	Tremor-ataxia-central hypomyelination syndrome	HP:0040282 - Frequent	138
HP:0000684	HP:0000684	Delayed eruption of teeth	0	POLR3A CL E G H	11128	30074	OMIM:264090	Wiedemann-Rautenstrauch syndrome	.	138
HP:0000684	HP:0000684	Delayed eruption of teeth	0	POLR3B CL E G H	55703	30348	OMIM:614381	Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism	.	67
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PORCN CL E G H	64840	17652	OMIM:305600	Focal dermal hypoplasia	.	20
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PRKACA CL E G H	5566	9380	ORPHA:289	Ellis Van Creveld syndrome	HP:0040283 - Occasional	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PRKACB CL E G H	5567	9381	ORPHA:289	Ellis Van Creveld syndrome	HP:0040283 - Occasional	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PRKAR1A CL E G H	5573	9388	ORPHA:950	Acrodysostosis	HP:0040282 - Frequent	134
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PRKAR1A CL E G H	5573	9388	OMIM:101800	Acrodysostosis 1, with or without hormone resistance	.	134
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PTCH1 CL E G H	5727	9585	ORPHA:77301	Monosomy 9q22.3	HP:0040282 - Frequent	665
HP:0000684	HP:0000684	Delayed eruption of teeth	0	PTHLH CL E G H	5744	9607	OMIM:613382	Brachydactyly, type E2	HP:0040283 - Occasional	6
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RAD21 CL E G H	5885	9811	ORPHA:199	Cornelia de Lange syndrome	HP:0040281 - Very frequent	25
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RAI1 CL E G H	10743	9834	ORPHA:819	Smith-Magenis syndrome		150
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RECQL4 CL E G H	9401	9949	ORPHA:221016	Rothmund-Thomson syndrome type 2	HP:0040283 - Occasional	445
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RECQL4 CL E G H	9401	9949	OMIM:268400	ROTHMUND-THOMSON SYNDROME; RTS		445
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RIC1 CL E G H	57589	17686	OMIM:618761	CATIFA SYNDROME; CATIFA
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ROR2 CL E G H	4920	10257	OMIM:113000	Brachydactyly, type B1		120
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ROR2 CL E G H	4920	10257	OMIM:268310	Robinow syndrome, autosomal recessive		120
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RPS6KA3 CL E G H	6197	10432	ORPHA:192	Coffin-Lowry syndrome	HP:0040283 - Occasional	65
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RUNX2 CL E G H	860	10472	OMIM:119600	Cleidocranial dysplasia		90
HP:0000684	HP:0000684	Delayed eruption of teeth	0	RUNX2 CL E G H	860	10472	ORPHA:1452	Cleidocranial dysplasia	HP:0040282 - Frequent	90
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SATB1 CL E G H	6304	10541	OMIM:619229	KOHLSCHUTTER-TONZ SYNDROME-LIKE; KTZSL
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SBDS CL E G H	51119	19440	ORPHA:811	Shwachman-Diamond syndrome	HP:0040284 - Very rare	26
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SEC23A CL E G H	10484	10701	OMIM:607812	Craniolenticulosutural dysplasia	.	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SEC23A CL E G H	10484	10701	ORPHA:50814	Craniolenticulosutural dysplasia	HP:0040281 - Very frequent	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SEC24D CL E G H	9871	10706	ORPHA:2050	Cole-Carpenter syndrome	HP:0040281 - Very frequent	5
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SEMA3E CL E G H	9723	10727	ORPHA:138	CHARGE syndrome	HP:0040282 - Frequent	16
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SETBP1 CL E G H	26040	15573	ORPHA:798	Schinzel-Giedion syndrome	HP:0040283 - Occasional	143
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SETD2 CL E G H	29072	18420	ORPHA:821	Sotos syndrome		60
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SFRP4 CL E G H	6424	10778	OMIM:265900	Pyle disease	HP:0040283 - Occasional	3
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SH3PXD2B CL E G H	285590	29242	ORPHA:137834	Frank-Ter Haar syndrome	HP:0040282 - Frequent	134
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SLC13A5 CL E G H	284111	23089	OMIM:615905	Epileptic encephalopathy, early infantile, 25, with amelogenesis imperfecta	.	73
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SLC1A2 CL E G H	6506	10940	OMIM:617105	Epileptic encephalopathy, early infantile, 41		3
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SLC29A3 CL E G H	55315	23096	ORPHA:1782	Dysosteosclerosis	HP:0040281 - Very frequent	68
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SLC37A4 CL E G H	2542	4061	ORPHA:79259	Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib		110
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SLC39A13 CL E G H	91252	20859	OMIM:612350	Ehlers-Danlos syndrome, spondylodysplastic type, 3	.	24
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMARCA4 CL E G H	6597	11100	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	617
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMARCB1 CL E G H	6598	11103	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	87
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMARCB1 CL E G H	6598	11103	OMIM:614608	Coffin-Siris syndrome 3		87
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMARCC2 CL E G H	6601	11105	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	1
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMARCD1 CL E G H	6602	11106	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMARCE1 CL E G H	6605	11109	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	47
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMC1A CL E G H	8243	11111	ORPHA:199	Cornelia de Lange syndrome	HP:0040281 - Very frequent	135
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SMC3 CL E G H	9126	2468	ORPHA:199	Cornelia de Lange syndrome	HP:0040281 - Very frequent	91
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SNX10 CL E G H	29887	14974	ORPHA:667	Autosomal recessive malignant osteopetrosis	HP:0040281 - Very frequent	2
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SNX14 CL E G H	57231	14977	OMIM:616354	Spinocerebellar ataxia, autosomal recessive 20	.	14
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SOX11 CL E G H	6664	11191	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent	14
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SOX11 CL E G H	6664	11191	OMIM:615866	Mental retardation, autosomal dominant 27		14
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SOX4 CL E G H	6659	11200	ORPHA:1465	Coffin-Siris syndrome	HP:0040282 - Frequent
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SP7 CL E G H	121340	17321	OMIM:613849	Osteogenesis imperfecta, type XII	.	34
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SRP54 CL E G H	6729	11301	ORPHA:811	Shwachman-Diamond syndrome	HP:0040284 - Very rare
HP:0000684	HP:0000684	Delayed eruption of teeth	0	STAT3 CL E G H	6774	11364	ORPHA:2314	Autosomal dominant hyper-IgE syndrome	HP:0040282 - Frequent	110
HP:0000684	HP:0000684	Delayed eruption of teeth	0	STX16 CL E G H	8675	11431	ORPHA:94089	Pseudohypoparathyroidism type 1B	HP:0040282 - Frequent	86
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SUMO1 CL E G H	7341	12502	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	8
HP:0000684	HP:0000684	Delayed eruption of teeth	0	SUOX CL E G H	6821	11460	OMIM:272300	SULFOCYSTEINURIA	.	40
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TBC1D24 CL E G H	57465	29203	ORPHA:79500	DOORS syndrome		271
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TCIRG1 CL E G H	10312	11647	ORPHA:667	Autosomal recessive malignant osteopetrosis	HP:0040281 - Very frequent	82
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TCIRG1 CL E G H	10312	11647	ORPHA:1782	Dysosteosclerosis	HP:0040281 - Very frequent	82
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TFAP2B CL E G H	7021	11743	ORPHA:46627	Char syndrome		104
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TGFA CL E G H	7039	11765	ORPHA:99798	Oligodontia	HP:0040282 - Frequent
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TGFB1 CL E G H	7040	11766	ORPHA:1328	Camurati-Engelmann disease	HP:0040283 - Occasional	13
HP:0000684	HP:0000684	Delayed eruption of teeth	0	THRA CL E G H	7067	11796	OMIM:614450	Hypothyroidism, congenital, nongoitrous, 6	.	9
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TNFRSF11A CL E G H	8792	11908	ORPHA:1782	Dysosteosclerosis	HP:0040281 - Very frequent	72
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TNFSF11 CL E G H	8600	11926	ORPHA:667	Autosomal recessive malignant osteopetrosis	HP:0040281 - Very frequent	44
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TONSL CL E G H	4796	7801	ORPHA:93357	SPONASTRIME dysplasia
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TRIP11 CL E G H	9321	12305	ORPHA:166272	Odontochondrodysplasia	HP:0040282 - Frequent	133
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TRIP11 CL E G H	9321	12305	OMIM:184260	Osteochondrodysplasia	.	133
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TRPS1 CL E G H	7227	12340	OMIM:190350	Trichorhinophalangeal syndrome, type I	.	171
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TWIST2 CL E G H	117581	20670	OMIM:209885	Barber-Say syndrome	HP:0040283 - Occasional	7
HP:0000684	HP:0000684	Delayed eruption of teeth	0	TWIST2 CL E G H	117581	20670	ORPHA:1231	Barber-Say syndrome	HP:0040281 - Very frequent	7
HP:0000684	HP:0000684	Delayed eruption of teeth	0	UBR1 CL E G H	197131	16808	ORPHA:2315	Johanson-Blizzard syndrome	HP:0040282 - Frequent	25
HP:0000684	HP:0000684	Delayed eruption of teeth	0	VDR CL E G H	7421	12679	OMIM:277440	Vitamin d-dependent rickets, type 2A	.	104
HP:0000684	HP:0000684	Delayed eruption of teeth	0	WNT10A CL E G H	80326	13829	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	71
HP:0000684	HP:0000684	Delayed eruption of teeth	0	WNT10B CL E G H	7480	12775	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	4
HP:0000684	HP:0000684	Delayed eruption of teeth	0	WNT5A CL E G H	7474	12784	OMIM:180700	Robinow syndrome, autosomal dominant 1	.	98
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ZEB2 CL E G H	9839	14881	OMIM:235730	Mowat-Wilson syndrome		362
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ZEB2 CL E G H	9839	14881	ORPHA:261552	Mowat-Wilson syndrome due to a ZEB2 point mutation	HP:0040283 - Occasional	362
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ZEB2 CL E G H	9839	14881	ORPHA:261537	Mowat-Wilson syndrome due to monosomy 2q22	HP:0040283 - Occasional	362
HP:0000684	HP:0000684	Delayed eruption of teeth	0	ZMPSTE24 CL E G H	10269	12877	ORPHA:740	Hutchinson-Gilford progeria syndrome	HP:0040283 - Occasional	83
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	ADAMTSL1 CL E G H	92949	14632	ORPHA:521445	Microcephaly-facial dysmorphism-ocular anomalies-multiple congenital anomalies syndrome	HP:0040282 - Frequent
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	APC2 CL E G H	10297	24036	ORPHA:821	Sotos syndrome	HP:0040284 - Very rare	1
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	ATP6V1B2 CL E G H	526	854	ORPHA:79500	DOORS syndrome	HP:0040283 - Occasional	5
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	AXIN2 CL E G H	8313	904	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	435
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	CAMK2B CL E G H	816	1461	OMIM:617799	Mental retardation, autosomal dominant 54
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	CTSK CL E G H	1513	2536	ORPHA:763	Pycnodysostosis		39
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	CTSK CL E G H	1513	2536	ORPHA:763	Pycnodysostosis		39
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	CTSK CL E G H	1513	2536	OMIM:265800	PYCNODYSOSTOSIS	.	39
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	CTSK CL E G H	1513	2536	OMIM:265800	PYCNODYSOSTOSIS	.	39
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	DEAF1 CL E G H	10522	14677	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	33
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	EDA CL E G H	1896	3157	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	115
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	EDARADD CL E G H	128178	14341	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	56
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	EDNRA CL E G H	1909	3179	OMIM:616367	Mandibulofacial dysostosis with alopecia	.	3
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC1 CL E G H	2067	3433	ORPHA:90322	Cockayne syndrome type 2	HP:0040283 - Occasional	20
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC4 CL E G H	2072	3436	ORPHA:90321	Cockayne syndrome type 1	HP:0040283 - Occasional	158
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC6 CL E G H	2074	3438	ORPHA:90321	Cockayne syndrome type 1	HP:0040283 - Occasional	199
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC6 CL E G H	2074	3438	ORPHA:90322	Cockayne syndrome type 2	HP:0040283 - Occasional	199
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC6 CL E G H	2074	3438	OMIM:133540	Cockayne syndrome, type B	.	199
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC8 CL E G H	1161	3439	OMIM:216400	Cockayne syndrome A	.	55
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC8 CL E G H	1161	3439	ORPHA:90321	Cockayne syndrome type 1	HP:0040283 - Occasional	55
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	ERCC8 CL E G H	1161	3439	ORPHA:90322	Cockayne syndrome type 2	HP:0040283 - Occasional	55
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	FAM20A CL E G H	54757	23015	OMIM:204690	Enamel-Renal syndrome	.	16
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	FGF10 CL E G H	2255	3666	OMIM:149730	Lacrimoauriculodentodigital syndrome	.	17
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	FGFR1 CL E G H	2260	3688	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	172
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	FGFR2 CL E G H	2263	3689	OMIM:149730	Lacrimoauriculodentodigital syndrome	.	175
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	FGFR3 CL E G H	2261	3690	OMIM:149730	Lacrimoauriculodentodigital syndrome	.	145
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	FLII CL E G H	2314	3750	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	GJA1 CL E G H	2697	4274	OMIM:218400	Craniometaphyseal dysplasia, autosomal recessive	.	68
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	IQSEC2 CL E G H	23096	29059	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	119
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	IRF6 CL E G H	3664	6121	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	99
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	KCNJ2 CL E G H	3759	6263	OMIM:170390	Andersen cardiodysrhythmic periodic paralysis	.	193
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	LEMD2 CL E G H	221496	21244	OMIM:619322	MARBACH-RUSTAD PROGEROID SYNDROME; MARUPS		1
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	LRP6 CL E G H	4040	6698	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	26
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	MIA3 CL E G H	375056	24008	OMIM:619269	ODONTOCHONDRODYSPLASIA 2 WITH HEARING LOSS AND DIABETES; ODCD2
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	MSX1 CL E G H	4487	7391	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	12
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	NPHS1 CL E G H	4868	7908	ORPHA:839	Congenital nephrotic syndrome, Finnish type	HP:0040281 - Very frequent	241
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	NSD1 CL E G H	64324	14234	ORPHA:821	Sotos syndrome	HP:0040284 - Very rare	544
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	PAX9 CL E G H	5083	8623	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	58
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	PIGF CL E G H	5281	8962	OMIM:619356	ONYCHODYSTROPHY, OSTEODYSTROPHY, IMPAIRED INTELLECTUAL DEVELOPMENT, AND SEIZURES SYNDROME; OORS
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	RAI1 CL E G H	10743	9834	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	150
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	ROR2 CL E G H	4920	10257	OMIM:113000	Brachydactyly, type B1	.	120
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	ROR2 CL E G H	4920	10257	OMIM:268310	Robinow syndrome, autosomal recessive	.	120
HP:0000684	HP:0000680	Delayed eruption of primary teeth	1	RUNX2 CL E G H	860	10472	OMIM:119600	Cleidocranial dysplasia	.	90
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	RUNX2 CL E G H	860	10472	OMIM:119600	Cleidocranial dysplasia	.	90
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	SETD2 CL E G H	29072	18420	ORPHA:821	Sotos syndrome	HP:0040284 - Very rare	60
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	SLC37A4 CL E G H	2542	4061	ORPHA:79259	Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib	HP:0040283 - Occasional	110
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	SMARCB1 CL E G H	6598	11103	OMIM:614608	Coffin-Siris syndrome 3	.	87
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	SUMO1 CL E G H	7341	12502	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	8
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	TBC1D24 CL E G H	57465	29203	ORPHA:79500	DOORS syndrome	HP:0040283 - Occasional	271
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	TFAP2B CL E G H	7021	11743	ORPHA:46627	Char syndrome		104
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	TGFA CL E G H	7039	11765	ORPHA:99798	Oligodontia	HP:0040282 - Frequent
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	TONSL CL E G H	4796	7801	ORPHA:93357	SPONASTRIME dysplasia	HP:0040283 - Occasional
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	WNT10A CL E G H	80326	13829	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	71
HP:0000684	HP:0000696	Delayed eruption of permanent teeth	1	WNT10B CL E G H	7480	12775	ORPHA:99798	Oligodontia	HP:0040282 - Frequent	4
HP:0000684	HP:0006321	Multiple non-erupting secondary teeth	2	CL E G H
HP:0000684	HP:0006291	Marked delay in eruption of permanent teeth	2	CL E G H
HP:0000684	HP:0008498	No permanent dentition	2	APC2 CL E G H	10297	24036	ORPHA:821	Sotos syndrome	HP:0040284 - Very rare	1
HP:0000684	HP:0008498	No permanent dentition	2	NSD1 CL E G H	64324	14234	ORPHA:821	Sotos syndrome	HP:0040284 - Very rare	544
HP:0000684	HP:0008498	No permanent dentition	2	SETD2 CL E G H	29072	18420	ORPHA:821	Sotos syndrome	HP:0040284 - Very rare	60
HP:0000684	HP:0008498	No permanent dentition	2	TFAP2B CL E G H	7021	11743	ORPHA:46627	Char syndrome	HP:0040283 - Occasional	104

Genes (166) :ABCA5 ACP5 ADAMTS3 ADAMTSL1 AMER1 AMMECR1 ANAPC1 ANTXR1 APC2 ARID1A ARID1B ARID2 ARSB ATP6V0A2 ATP6V1B2 AXIN2 BCOR BRD4 CAMK2B CCBE1 CCDC8 CDH11 CHD7 CHST3 CLCN7 CTSK CUL7 CYP27B1 CYP2R1 DEAF1 DMP1 DNAJC21 DPF2 DPYD DVL1 DYNC2LI1 EDA EDA2R EDARADD EDNRA EFL1 ELMO2 ENPP1 ERCC1 ERCC4 ERCC6 ERCC8 EVC EVC2 FAM20A FAT4 FGD1 FGF10 FGF3 FGFR1 FGFR2 FGFR3 FLII FLNA GDF5 GHR GJA1 GLI1 GNAS GNB2 HDAC4 HDAC8 IDS IGF1 IKBKG IL11RA IQSEC2 IRF6 KAT6B KCNH1 KCNJ2 KCTD1 LEMD2 LIG4 LMNA LONP1 LRP6 MIA3 MMP2 MSX1 MYSM1 NAA10 NIPBL NPHS1 NSD1 NSUN2 OBSL1 OCRL P4HB PAPPA2 PAX9 PDE4D PDGFRB PIGA PIGF PIK3R1 POLR3A POLR3B PORCN PRKACA PRKACB PRKAR1A PTCH1 PTHLH RAD21 RAI1 RECQL4 RIC1 ROR2 RPS6KA3 RUNX2 SATB1 SBDS SEC23A SEC24D SEMA3E SETBP1 SETD2 SFRP4 SH3PXD2B SLC13A5 SLC1A2 SLC29A3 SLC37A4 SLC39A13 SMARCA4 SMARCB1 SMARCC2 SMARCD1 SMARCE1 SMC1A SMC3 SNX10 SNX14 SOX11 SOX4 SP7 SRP54 STAT3 STX16 SUMO1 SUOX TBC1D24 TCIRG1 TFAP2B TGFA TGFB1 THRA TNFRSF11A TNFSF11 TONSL TRIP11 TRPS1 TWIST2 UBR1 VDR WNT10A WNT10B WNT5A ZEB2 ZMPSTE24

Diseases (148) :ORPHA:2026 ORPHA:1855 ORPHA:2136 ORPHA:521445 ORPHA:2780 OMIM:300990 ORPHA:221008 ORPHA:2067 ORPHA:821 ORPHA:1465 OMIM:614607 OMIM:135900 OMIM:253200 ORPHA:2834 OMIM:278250 ORPHA:79500 ORPHA:99798 ORPHA:568 OMIM:300166 ORPHA:2712 ORPHA:199 OMIM:617799 OMIM:235510 ORPHA:2616 OMIM:211380 OMIM:619736 ORPHA:138 ORPHA:263463 OMIM:143095 ORPHA:667 ORPHA:763 OMIM:265800 ORPHA:289157 OMIM:264700 ORPHA:819 ORPHA:289176 ORPHA:811 ORPHA:1675 OMIM:180700 ORPHA:289 ORPHA:181 OMIM:616367 ORPHA:3019 ORPHA:90322 ORPHA:90321 OMIM:214150 OMIM:133540 OMIM:216400 OMIM:225500 ORPHA:1031 OMIM:204690 ORPHA:915 OMIM:149730 ORPHA:2791 OMIM:101200 ORPHA:87 OMIM:305620 ORPHA:2484 OMIM:309350 ORPHA:63442 ORPHA:633 OMIM:218400 OMIM:257850 ORPHA:79443 ORPHA:94089 ORPHA:79444 OMIM:103580 OMIM:612462 OMIM:612463 OMIM:619503 OMIM:619797 OMIM:309900 ORPHA:73272 OMIM:308300 ORPHA:464 OMIM:614188 ORPHA:85201 OMIM:606170 ORPHA:420561 OMIM:135500 OMIM:170390 ORPHA:2036 OMIM:619322 ORPHA:235 ORPHA:740 ORPHA:1458 OMIM:600373 OMIM:619269 OMIM:259600 ORPHA:2228 ORPHA:508542 OMIM:122470 ORPHA:839 OMIM:612921 ORPHA:534 ORPHA:2050 OMIM:619489 ORPHA:950 OMIM:601812 OMIM:301072 OMIM:619356 OMIM:269880 ORPHA:447896 OMIM:264090 OMIM:614381 OMIM:305600 OMIM:101800 ORPHA:77301 OMIM:613382 ORPHA:221016 OMIM:268400 OMIM:618761 OMIM:113000 OMIM:268310 ORPHA:192 OMIM:119600 ORPHA:1452 OMIM:619229 OMIM:607812 ORPHA:50814 ORPHA:798 OMIM:265900 ORPHA:137834 OMIM:615905 OMIM:617105 ORPHA:1782 ORPHA:79259 OMIM:612350 OMIM:614608 OMIM:616354 OMIM:615866 OMIM:613849 ORPHA:2314 OMIM:272300 ORPHA:46627 ORPHA:1328 OMIM:614450 ORPHA:93357 ORPHA:166272 OMIM:184260 OMIM:190350 OMIM:209885 ORPHA:1231 ORPHA:2315 OMIM:277440 OMIM:235730 ORPHA:261552 ORPHA:261537

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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