Human Phenotype Ontology 
Grandparent Node:
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Abnormality of blood and blood-forming tissues (HP:0001871)help
Grandparent Node:
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Neoplasm by anatomical site (HP:0011793)help
Parent Node:
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Hematological neoplasm (HP:0004377)help
..Starting node
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Multiple myeloma (HP:0006775)help
Term ID: 6775
Name: Multiple myeloma
Synonym: Kahler's disease; Plasmocytoma
Definition: A malignant plasma cell tumor growing within soft tissue or within the skeleton.
Comments:
Reference: HP:0006775
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandLeukemia (HP:0001909) help
..expandLymphoma (HP:0002665) help
..expandLymphoproliferative disorder (HP:0005523) help
..expandMalignant eosinophil proliferation (HP:0006782) help
..expandMyelodysplasia (HP:0002863) help
..expandPlasmacytoma (HP:0011857) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0006775HP:0006775Multiple myeloma0ASXL1 CL E G H17102318318ORPHA:98849Systemic mastocytosis with associated hematologic neoplasmHP:0040284 - Very rare145
HP:0006775HP:0006775Multiple myeloma0CCND1 CL E G H5951582OMIM:254500Multiple myeloma.1
HP:0006775HP:0006775Multiple myeloma0GBA1 CL E G H26294177OMIM:230800Gaucher disease, type I.
HP:0006775HP:0006775Multiple myeloma0KIT CL E G H38156342ORPHA:98849Systemic mastocytosis with associated hematologic neoplasmHP:0040284 - Very rare327
HP:0006775HP:0006775Multiple myeloma0LIG4 CL E G H39816601OMIM:254500Multiple myeloma.88
HP:0006775HP:0006775Multiple myeloma0SRSF2 CL E G H642710783ORPHA:98849Systemic mastocytosis with associated hematologic neoplasmHP:0040284 - Very rare1
HP:0006775HP:0006775Multiple myeloma0TET2 CL E G H5479025941ORPHA:98849Systemic mastocytosis with associated hematologic neoplasmHP:0040284 - Very rare3


Genes (7) :ASXL1 CCND1 GBA1 KIT LIG4 SRSF2 TET2

Diseases (3) :ORPHA:98849 OMIM:254500 OMIM:230800
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.