Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the pancreas (HP:0001732)help
Grandparent Node:
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Neoplasm by anatomical site (HP:0011793)help
Parent Node:
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Neoplasm of the pancreas (HP:0002894)help
..Starting node
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Pancreatic adenocarcinoma (HP:0006725)help
Term ID: 6725
Name: Pancreatic adenocarcinoma
Synonym:
Definition: The presence of an adenocarcinoma of the pancreas.
Comments:
Reference: HP:0006725
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandPancreatic islet cell adenoma (HP:0008261) help
..expandPancreatic squamous cell carcinoma (HP:0012142) help
..expandPancreatoblastoma (HP:0100757) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0006725HP:0006725Pancreatic adenocarcinoma0BRCA1 CL E G H6721333Chromosome 19, ringCN036553ORPHA1125861100113705
HP:0006725HP:0006725Pancreatic adenocarcinoma0BRCA1 CL E G H6721333Chromosome 19, ringCN036553ORPHA1122071100113705
HP:0006725HP:0006725Pancreatic adenocarcinoma0BRCA2 CL E G H6751333Chromosome 19, ringCN036553ORPHA1147421101600185
HP:0006725HP:0006725Pancreatic adenocarcinoma0BRCA2 CL E G H6751333Chromosome 19, ringCN036553ORPHA1139121101600185
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDC73 CL E G H79577145001Hyperparathyroidism 2145001C1704981OMIM182816783607393
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDC73 CL E G H79577145001Hyperparathyroidism 2145001C1704981OMIM170416783607393
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDKN2A CL E G H10291333Chromosome 19, ringCN036553ORPHA110621787600160
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDKN2A CL E G H10291333Chromosome 19, ringCN036553ORPHA19711787600160
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDKN2A CL E G H1029606719Melanoma-pancreatic cancer syndrome606719C1838547OMIM110621787600160
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDKN2A CL E G H1029606719Melanoma-pancreatic cancer syndrome606719C1838547OMIM19711787600160
HP:0006725HP:0006725Pancreatic adenocarcinoma0KRAS CL E G H38451333Chromosome 19, ringCN036553ORPHA13416407190070
HP:0006725HP:0006725Pancreatic adenocarcinoma0KRAS CL E G H38451333Chromosome 19, ringCN036553ORPHA13316407190070
HP:0006725HP:0006725Pancreatic adenocarcinoma0PALB2 CL E G H797281333Chromosome 19, ringCN036553ORPHA1424526144610355
HP:0006725HP:0006725Pancreatic adenocarcinoma0PALB2 CL E G H797281333Chromosome 19, ringCN036553ORPHA1392526144610355
HP:0006725HP:0006725Pancreatic adenocarcinoma0PALLD CL E G H230221333Chromosome 19, ringCN036553ORPHA161417068608092
HP:0006725HP:0006725Pancreatic adenocarcinoma0PALLD CL E G H230221333Chromosome 19, ringCN036553ORPHA154617068608092
HP:0006725HP:0006725Pancreatic adenocarcinoma0SMAD4 CL E G H40891333Chromosome 19, ringCN036553ORPHA114956770600993
HP:0006725HP:0006725Pancreatic adenocarcinoma0SMAD4 CL E G H40891333Chromosome 19, ringCN036553ORPHA113596770600993
HP:0006725HP:0006725Pancreatic adenocarcinoma0TP53 CL E G H71571333Chromosome 19, ringCN036553ORPHA1246411998191170
HP:0006725HP:0006725Pancreatic adenocarcinoma0TP53 CL E G H71571333Chromosome 19, ringCN036553ORPHA1228011998191170
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDC73 CL E G H7957799880ORPHA082816783607393
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDC73 CL E G H7957799880ORPHA070416783607393
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDC73 CL E G H79577143ORPHA082816783607393
HP:0006725HP:0006725Pancreatic adenocarcinoma0CDC73 CL E G H79577143ORPHA070416783607393
HP:0006725HP:0006725Pancreatic adenocarcinoma0EPCAM CL E G H4072144ORPHA037411529185535
HP:0006725HP:0006725Pancreatic adenocarcinoma0EPCAM CL E G H4072144ORPHA036011529185535
HP:0006725HP:0006725Pancreatic adenocarcinoma0FAN1 CL E G H22909144ORPHA036129170613534
HP:0006725HP:0006725Pancreatic adenocarcinoma0FAN1 CL E G H22909144ORPHA035129170613534
HP:0006725HP:0006725Pancreatic adenocarcinoma0KRAS CL E G H3845144ORPHA03416407190070
HP:0006725HP:0006725Pancreatic adenocarcinoma0KRAS CL E G H3845144ORPHA03316407190070
HP:0006725HP:0006725Pancreatic adenocarcinoma0MLH1 CL E G H4292144ORPHA037637127120436
HP:0006725HP:0006725Pancreatic adenocarcinoma0MLH1 CL E G H4292144ORPHA035407127120436
HP:0006725HP:0006725Pancreatic adenocarcinoma0MLH3 CL E G H27030144ORPHA07637128604395
HP:0006725HP:0006725Pancreatic adenocarcinoma0MLH3 CL E G H27030144ORPHA06347128604395
HP:0006725HP:0006725Pancreatic adenocarcinoma0MSH2 CL E G H4436144ORPHA049647325609309
HP:0006725HP:0006725Pancreatic adenocarcinoma0MSH2 CL E G H4436144ORPHA046077325609309
HP:0006725HP:0006725Pancreatic adenocarcinoma0MSH6 CL E G H2956144ORPHA062197329600678
HP:0006725HP:0006725Pancreatic adenocarcinoma0MSH6 CL E G H2956144ORPHA057177329600678
HP:0006725HP:0006725Pancreatic adenocarcinoma0NTHL1 CL E G H4913454840ORPHA09028028602656
HP:0006725HP:0006725Pancreatic adenocarcinoma0NTHL1 CL E G H4913454840ORPHA07558028602656
HP:0006725HP:0006725Pancreatic adenocarcinoma0PIK3CA CL E G H5290144ORPHA06138975171834
HP:0006725HP:0006725Pancreatic adenocarcinoma0PIK3CA CL E G H5290144ORPHA05448975171834
HP:0006725HP:0006725Pancreatic adenocarcinoma0PMS1 CL E G H5378144ORPHA0929121600258
HP:0006725HP:0006725Pancreatic adenocarcinoma0PMS1 CL E G H5378144ORPHA0859121600258
HP:0006725HP:0006725Pancreatic adenocarcinoma0PMS2 CL E G H5395144ORPHA034219122600259
HP:0006725HP:0006725Pancreatic adenocarcinoma0PMS2 CL E G H5395144ORPHA031549122600259
HP:0006725HP:0006725Pancreatic adenocarcinoma0RNF43 CL E G H54894157798ORPHA032218505612482
HP:0006725HP:0006725Pancreatic adenocarcinoma0RNF43 CL E G H54894157798ORPHA022118505612482
HP:0006725HP:0006725Pancreatic adenocarcinoma0STK11 CL E G H67942869Hypertrophic osteoarthropathy, primary or idiopathicORPHA0194511389602216
HP:0006725HP:0006725Pancreatic adenocarcinoma0STK11 CL E G H67942869Hypertrophic osteoarthropathy, primary or idiopathicORPHA0182011389602216
HP:0006725HP:0006725Pancreatic adenocarcinoma0TGFBR2 CL E G H7048144ORPHA075011773190182
HP:0006725HP:0006725Pancreatic adenocarcinoma0TGFBR2 CL E G H7048144ORPHA069411773190182


Genes (22) :BRCA1 BRCA2 CDC73 CDKN2A EPCAM FAN1 KRAS MLH1 MLH3 MSH2 MSH6 NTHL1 PALB2 PALLD PIK3CA PMS1 PMS2 RNF43 SMAD4 STK11 TGFBR2 TP53

Diseases (9) :1333 99880 143 145001 606719 144 454840 157798 2869
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.