Human Phenotype Ontology

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	DiseaseId	DiseaseName	DiseaseMIM	ConceptID	Source	Typical association	ClinVar variants	HGNC ID	GeneMIM
HPO disease - gene - phenotype typical associations:
HP:0000632	HP:0000632	Lacrimation abnormality	0	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0000632	Lacrimation abnormality	0	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0000632	Lacrimation abnormality	0	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0000632	Lacrimation abnormality	0	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0000632	Lacrimation abnormality	0	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0000632	Lacrimation abnormality	0	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0000632	Lacrimation abnormality	0	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0100274	Gustatory lacrimation	1	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0000633	Decreased lacrimation	1	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0009926	Epiphora	1	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0100274	Gustatory lacrimation	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0000633	Decreased lacrimation	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0009926	Epiphora	1	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0100274	Gustatory lacrimation	1	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0000633	Decreased lacrimation	1	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0009926	Epiphora	1	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0100274	Gustatory lacrimation	1	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0000633	Decreased lacrimation	1	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0009926	Epiphora	1	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0009926	Epiphora	1	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0000633	Decreased lacrimation	1	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0100274	Gustatory lacrimation	1	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0000633	Decreased lacrimation	1	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0100274	Gustatory lacrimation	1	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0009926	Epiphora	1	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0009926	Epiphora	1	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0000633	Decreased lacrimation	1	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0100274	Gustatory lacrimation	1	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0000522	Alacrima	2	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0031731	Increased tear production	2	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0031734	Lacrimal pump failure	2	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0031881	Decreased tear drainage	2	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0000522	Alacrima	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0031731	Increased tear production	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0031734	Lacrimal pump failure	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0031881	Decreased tear drainage	2	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0000522	Alacrima	2	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0031731	Increased tear production	2	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0031881	Decreased tear drainage	2	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0031734	Lacrimal pump failure	2	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0000522	Alacrima	2	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0031731	Increased tear production	2	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0031734	Lacrimal pump failure	2	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0031881	Decreased tear drainage	2	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0031881	Decreased tear drainage	2	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0031734	Lacrimal pump failure	2	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0000522	Alacrima	2	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0031731	Increased tear production	2	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0000522	Alacrima	2	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0031731	Increased tear production	2	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0031881	Decreased tear drainage	2	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0031734	Lacrimal pump failure	2	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0031881	Decreased tear drainage	2	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0031734	Lacrimal pump failure	2	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0000522	Alacrima	2	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0031731	Increased tear production	2	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0031732	Increased basal tear production	3	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0031733	Reflex tearing	3	EYA1 CL E G H	2138	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	434	3519	601653
HP:0000632	HP:0031732	Increased basal tear production	3	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0031733	Reflex tearing	3	LIFR CL E G H	3977	3206				ORPHA	1	721	6597	151443
HP:0000632	HP:0031732	Increased basal tear production	3	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0031733	Reflex tearing	3	PAX3 CL E G H	5077	894				ORPHA	1	295	8617	606597
HP:0000632	HP:0031732	Increased basal tear production	3	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0031733	Reflex tearing	3	SCN9A CL E G H	6335	167400	Paroxysmal extreme pain disorder	167400	C1833661	OMIM	1	1907	10597	603415
HP:0000632	HP:0031733	Reflex tearing	3	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0031732	Increased basal tear production	3	SIX1 CL E G H	6495	113650	Melnick-Fraser syndrome	113650	C0265234	OMIM	1	157	10887	601205
HP:0000632	HP:0031732	Increased basal tear production	3	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0031733	Reflex tearing	3	TP63 CL E G H	8626	1896	Dominant cleft palate			ORPHA	1	508	15979	603273
HP:0000632	HP:0031733	Reflex tearing	3	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HP:0000632	HP:0031732	Increased basal tear production	3	UBR1 CL E G H	197131	2315	Fetal warfarin syndrome			ORPHA	1	236	16808	605981
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000632	HP:0000632	Lacrimation abnormality	0	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0000632	Lacrimation abnormality	0	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0000632	Lacrimation abnormality	0	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0000632	Lacrimation abnormality	0	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0000632	Lacrimation abnormality	0	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0000632	Lacrimation abnormality	0	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0000632	Lacrimation abnormality	0	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0000632	Lacrimation abnormality	0	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0000632	Lacrimation abnormality	0	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0000632	Lacrimation abnormality	0	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0000632	Lacrimation abnormality	0	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0000632	Lacrimation abnormality	0	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0000632	Lacrimation abnormality	0	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0000632	Lacrimation abnormality	0	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0000632	Lacrimation abnormality	0	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0000632	Lacrimation abnormality	0	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0000632	Lacrimation abnormality	0	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0000632	Lacrimation abnormality	0	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0000632	Lacrimation abnormality	0	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0000632	Lacrimation abnormality	0	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0009926	Epiphora	1	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0100274	Gustatory lacrimation	1	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0000633	Decreased lacrimation	1	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0000633	Decreased lacrimation	1	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0100274	Gustatory lacrimation	1	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0009926	Epiphora	1	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0009926	Epiphora	1	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0100274	Gustatory lacrimation	1	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0000633	Decreased lacrimation	1	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0009926	Epiphora	1	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0000633	Decreased lacrimation	1	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0100274	Gustatory lacrimation	1	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0009926	Epiphora	1	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0000633	Decreased lacrimation	1	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0100274	Gustatory lacrimation	1	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0100274	Gustatory lacrimation	1	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0000633	Decreased lacrimation	1	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0009926	Epiphora	1	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0000633	Decreased lacrimation	1	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0100274	Gustatory lacrimation	1	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0009926	Epiphora	1	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0009926	Epiphora	1	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0000633	Decreased lacrimation	1	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0100274	Gustatory lacrimation	1	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0000633	Decreased lacrimation	1	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0100274	Gustatory lacrimation	1	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0009926	Epiphora	1	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0009926	Epiphora	1	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0100274	Gustatory lacrimation	1	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0000633	Decreased lacrimation	1	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0000633	Decreased lacrimation	1	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0100274	Gustatory lacrimation	1	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0009926	Epiphora	1	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0009926	Epiphora	1	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0000633	Decreased lacrimation	1	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0100274	Gustatory lacrimation	1	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0009926	Epiphora	1	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0100274	Gustatory lacrimation	1	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0000633	Decreased lacrimation	1	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0100274	Gustatory lacrimation	1	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0000633	Decreased lacrimation	1	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0009926	Epiphora	1	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0009926	Epiphora	1	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0100274	Gustatory lacrimation	1	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0000633	Decreased lacrimation	1	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0000633	Decreased lacrimation	1	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0100274	Gustatory lacrimation	1	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0009926	Epiphora	1	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0009926	Epiphora	1	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0100274	Gustatory lacrimation	1	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0000633	Decreased lacrimation	1	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0000633	Decreased lacrimation	1	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0100274	Gustatory lacrimation	1	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0009926	Epiphora	1	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0000633	Decreased lacrimation	1	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0100274	Gustatory lacrimation	1	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0009926	Epiphora	1	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0009926	Epiphora	1	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0000633	Decreased lacrimation	1	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0100274	Gustatory lacrimation	1	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0031734	Lacrimal pump failure	2	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0031881	Decreased tear drainage	2	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0000522	Alacrima	2	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0031731	Increased tear production	2	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0000522	Alacrima	2	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0031731	Increased tear production	2	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0031881	Decreased tear drainage	2	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0031734	Lacrimal pump failure	2	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0031734	Lacrimal pump failure	2	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0031881	Decreased tear drainage	2	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0000522	Alacrima	2	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0031731	Increased tear production	2	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0031881	Decreased tear drainage	2	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0031734	Lacrimal pump failure	2	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0000522	Alacrima	2	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0031731	Increased tear production	2	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0031881	Decreased tear drainage	2	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0031734	Lacrimal pump failure	2	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0000522	Alacrima	2	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0031731	Increased tear production	2	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0000522	Alacrima	2	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0031731	Increased tear production	2	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0031881	Decreased tear drainage	2	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0031734	Lacrimal pump failure	2	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0000522	Alacrima	2	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0031731	Increased tear production	2	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0031881	Decreased tear drainage	2	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0031734	Lacrimal pump failure	2	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0031881	Decreased tear drainage	2	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0031734	Lacrimal pump failure	2	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0000522	Alacrima	2	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0031731	Increased tear production	2	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0000522	Alacrima	2	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0031731	Increased tear production	2	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0031881	Decreased tear drainage	2	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0031734	Lacrimal pump failure	2	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0031881	Decreased tear drainage	2	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0031734	Lacrimal pump failure	2	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0000522	Alacrima	2	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0031731	Increased tear production	2	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0000522	Alacrima	2	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0031731	Increased tear production	2	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0031881	Decreased tear drainage	2	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0031734	Lacrimal pump failure	2	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0031881	Decreased tear drainage	2	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0031734	Lacrimal pump failure	2	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0000522	Alacrima	2	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0031731	Increased tear production	2	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0031734	Lacrimal pump failure	2	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0031881	Decreased tear drainage	2	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0000522	Alacrima	2	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0031731	Increased tear production	2	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0000522	Alacrima	2	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0031731	Increased tear production	2	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0031734	Lacrimal pump failure	2	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0031881	Decreased tear drainage	2	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0031881	Decreased tear drainage	2	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0031734	Lacrimal pump failure	2	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0000522	Alacrima	2	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0031731	Increased tear production	2	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0000522	Alacrima	2	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0031731	Increased tear production	2	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0031881	Decreased tear drainage	2	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0031734	Lacrimal pump failure	2	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0031881	Decreased tear drainage	2	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0031734	Lacrimal pump failure	2	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0000522	Alacrima	2	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0031731	Increased tear production	2	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0000522	Alacrima	2	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0031731	Increased tear production	2	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0031881	Decreased tear drainage	2	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0031734	Lacrimal pump failure	2	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0000522	Alacrima	2	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0031731	Increased tear production	2	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0031881	Decreased tear drainage	2	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0031734	Lacrimal pump failure	2	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0031881	Decreased tear drainage	2	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0031734	Lacrimal pump failure	2	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0000522	Alacrima	2	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0031731	Increased tear production	2	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0031733	Reflex tearing	3	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0031732	Increased basal tear production	3	ARID1A CL E G H	8289	1465				ORPHA	0	545	11110	603024
HP:0000632	HP:0031732	Increased basal tear production	3	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0031733	Reflex tearing	3	ARID1B CL E G H	57492	1465				ORPHA	0	1206	18040	614556
HP:0000632	HP:0031733	Reflex tearing	3	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0031732	Increased basal tear production	3	ARID2 CL E G H	196528	1465				ORPHA	0	227	18037	609539
HP:0000632	HP:0031733	Reflex tearing	3	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0031732	Increased basal tear production	3	BAZ1B CL E G H	9031	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	196	961	605681
HP:0000632	HP:0031733	Reflex tearing	3	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0031732	Increased basal tear production	3	CHD7 CL E G H	55636	138				ORPHA	0	2318	20626	608892
HP:0000632	HP:0031732	Increased basal tear production	3	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0031733	Reflex tearing	3	CLIP2 CL E G H	7461	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	181	2586	603432
HP:0000632	HP:0031732	Increased basal tear production	3	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0031733	Reflex tearing	3	DPF2 CL E G H	5977	1465				ORPHA	0	73	9964	601671
HP:0000632	HP:0031733	Reflex tearing	3	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0031732	Increased basal tear production	3	ELN CL E G H	2006	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	763	3327	130160
HP:0000632	HP:0031732	Increased basal tear production	3	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0031733	Reflex tearing	3	GTF2I CL E G H	2969	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	163	4659	601679
HP:0000632	HP:0031733	Reflex tearing	3	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0031732	Increased basal tear production	3	GTF2IRD1 CL E G H	9569	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	218	4661	604318
HP:0000632	HP:0031732	Increased basal tear production	3	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0031733	Reflex tearing	3	LIMK1 CL E G H	3984	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	201	6613	601329
HP:0000632	HP:0031733	Reflex tearing	3	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0031732	Increased basal tear production	3	OCRL CL E G H	4952	534	Acute myeloblastic leukemia without maturation			ORPHA	0	508	8108	300535
HP:0000632	HP:0031733	Reflex tearing	3	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0031732	Increased basal tear production	3	RFC2 CL E G H	5982	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	180	9970	600404
HP:0000632	HP:0031732	Increased basal tear production	3	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0031733	Reflex tearing	3	SEMA3E CL E G H	9723	138				ORPHA	0	451	10727	608166
HP:0000632	HP:0031733	Reflex tearing	3	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0031732	Increased basal tear production	3	SMARCA4 CL E G H	6597	1465				ORPHA	0	4367	11100	603254
HP:0000632	HP:0031732	Increased basal tear production	3	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0031733	Reflex tearing	3	SMARCB1 CL E G H	6598	1465				ORPHA	0	901	11103	601607
HP:0000632	HP:0031733	Reflex tearing	3	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0031732	Increased basal tear production	3	SMARCE1 CL E G H	6605	1465				ORPHA	0	660	11109	603111
HP:0000632	HP:0031732	Increased basal tear production	3	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0031733	Reflex tearing	3	SOX11 CL E G H	6664	1465				ORPHA	0	130	11191	600898
HP:0000632	HP:0031732	Increased basal tear production	3	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0031733	Reflex tearing	3	TBL2 CL E G H	26608	904	Blepharophimosis nasal groove growth retardation			ORPHA	0	166	11586	605842
HP:0000632	HP:0031733	Reflex tearing	3	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556
HP:0000632	HP:0031732	Increased basal tear production	3	TWIST2 CL E G H	117581	1807				ORPHA	0	98	20670	607556